Basic Information

Gene Symbol
-
Assembly
GCA_034770305.1
Location
JAPMIB010000013.1:1266276-1267602[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.001 0.037 15.2 0.6 1 23 30 53 30 53 0.96
2 12 0.0004 0.015 16.5 1.9 1 23 59 82 59 82 0.94
3 12 2.4e-05 0.0009 20.3 2.4 1 23 88 111 88 111 0.96
4 12 0.00018 0.0065 17.6 2.5 1 23 117 140 117 140 0.95
5 12 0.00021 0.0078 17.4 0.4 1 23 146 169 146 169 0.94
6 12 0.43 16 7.0 0.2 8 23 180 196 173 196 0.88
7 12 8e-05 0.0029 18.7 0.6 1 23 202 225 202 225 0.95
8 12 0.0017 0.061 14.6 4.7 1 23 231 254 231 254 0.95
9 12 2.6e-05 0.00097 20.2 1.1 1 23 260 283 260 283 0.96
10 12 5.3e-05 0.0019 19.3 1.0 1 23 289 312 289 312 0.97
11 12 0.027 0.98 10.8 6.5 1 23 318 341 318 341 0.97
12 12 0.18 6.5 8.2 0.7 1 14 347 360 347 362 0.89

Sequence Information

Coding Sequence
ATGGATGTaagtgaaaagaaaatcgaGGAAGATGTCTCGGAAGATAATTTTAGTGAACATGACATTGTGGTTTCGAATGACACACAgcacgtttgtgatatttgtcaggagacaTTTAcgctagaatcaagcatgataactCACCGAGaaacaattcacaatgatcggaaaaatttcgcatgcgacaagtgcgaagagaaatttgagttccgaagtcatttgagtagacatcaaatatTACTACACAAgggccgcaaagattttacatgcgaccagtgcgagaaaaaatttgtgaaaaaatcaagtttgtttacacaccaaaaattagtacacaaagatcgcgaaaattttatatgcaacaagtgcgagaggaaatttgagaataaatcaactttacttaaACACAATAagatattccacgaagtttttaaagattacttatgcgaAAAGTGCGTGAAAagatttgtaaacaaaaagagTTTGCTCGTGCACATAAAAGCAGTCCATGAGGATCGTTTCTCCTGTGATGAgcgcgagaagaaatttgtaataaaatctGATTTGATAAAGCACAAAAATACAGTCCACGATGGTAgtaaagattacttatgtgacaattgcgggaagaaatttggaaataaacgatatttgctcttgcatataacaacagtccatgagggtcgtaaagatcatgcatgtgacaaatgtgagaagaaatttgtacaaaaaagtcACTTGTTCTTCCACCAAAGAATAGTACATGAAGGTTGTAGAGATTTCaaatgcgataaatgcgagaaaagatttggatataaatataatttacttttGCACATAAAAGCAgttcatgagggtcgcaaagattacgcatgtgacaaatgtgagaatAAATTTAGGGATCAAAGCTATCTGATAAAACACAAAATGACAGTCCACGgtggtcggaaagattatgcatgcgacaagtgcaagaaaaaatttgggcaaAAATGTCACTTGCTCTTtcatcaaaggacagtacacgacagtgtcaaagattttacatgtgaCAGGTGCGGAAAGATATTTGGAACTAAACGAGAAACTATTTATCGGATAAGTGCTAAGTCCTAA
Protein Sequence
MDVSEKKIEEDVSEDNFSEHDIVVSNDTQHVCDICQETFTLESSMITHRETIHNDRKNFACDKCEEKFEFRSHLSRHQILLHKGRKDFTCDQCEKKFVKKSSLFTHQKLVHKDRENFICNKCERKFENKSTLLKHNKIFHEVFKDYLCEKCVKRFVNKKSLLVHIKAVHEDRFSCDEREKKFVIKSDLIKHKNTVHDGSKDYLCDNCGKKFGNKRYLLLHITTVHEGRKDHACDKCEKKFVQKSHLFFHQRIVHEGCRDFKCDKCEKRFGYKYNLLLHIKAVHEGRKDYACDKCENKFRDQSYLIKHKMTVHGGRKDYACDKCKKKFGQKCHLLFHQRTVHDSVKDFTCDRCGKIFGTKRETIYRISAKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-