Basic Information

Gene Symbol
-
Assembly
GCA_034770305.1
Location
JAPMIB010000004.1:2201812-2203023[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.00059 0.022 16.0 4.0 1 23 30 53 30 53 0.96
2 13 0.00031 0.011 16.9 2.3 1 23 59 82 59 82 0.96
3 13 0.0063 0.23 12.7 0.8 5 23 92 111 91 111 0.93
4 13 0.15 5.7 8.4 1.9 1 23 117 140 117 140 0.90
5 13 1.1e-05 0.00041 21.4 1.5 1 23 146 169 146 169 0.96
6 13 4e-06 0.00015 22.8 1.4 1 23 175 198 175 198 0.97
7 13 1.9e-05 0.00069 20.7 2.0 1 23 204 227 204 227 0.97
8 13 4.5e-05 0.0017 19.5 3.9 1 23 233 256 233 256 0.98
9 13 0.01 0.37 12.1 0.4 1 23 262 285 262 285 0.97
10 13 2.7e-06 0.0001 23.3 1.8 1 23 291 314 291 314 0.97
11 13 9e-06 0.00033 21.7 1.0 1 23 320 343 320 343 0.97
12 13 0.0021 0.078 14.2 1.3 1 23 349 372 349 372 0.98
13 13 1.8e-05 0.00066 20.7 1.1 1 23 378 401 378 401 0.97

Sequence Information

Coding Sequence
atggataaaattaAGGAGAAATCCGATGAAATCGTTTCAAAAGACAATTTAAGGGAACACGACAATGTTGTTtcagacgaaaaaaaacatacttgTGATATTTGCCACGAGACATTCACACTAAAATCAAGCATGATGAAACACCGAGACACCattcacaatgaacaaaaagttttcgcatgtgacaagtgcgaacagaaatttgagtttcgaagtcatttgagtagacaccaaatatcagttcATAAAAGCCGCAAAGATTATAAATTcgaccagtgcgagaagaaatttgtgaaaaaatcaagtttgtttacacaccaaaaatttgttcacaaaaaaCGCGAAGATTTCtcatgtaacaagtgcgagagaaaatttgaaaataaattaattttacttaagcataacaaaatattccacgaagtctccaaagattatttatgtgaaaagtgcgcgaaaagatttaatactaaaaataatctattgaagcacataaaaacagtacacgagggttgcaaagatttcgcatgtgacaaatgcgagaagaaatttggacaaaattcAGATTTGTTTaagcatcaaaagacagttcacgagggtcgcaaagattttgcatgtgacaaatgcgagaagaaattcggacaaaaaaaatatttgttgcggcaccaaaaaacagttcacgaaggtcgcaaagatttcacatgtgacaaatgcgagaagaaattcggacaaaaatgtaatttgctCACCCACCAAAGGATGgtccacgagggtcgtaaagattacccgtgcgacaagtgcgagaagaaattcggacaaagaTGGATTATGATtcagcaccaaaaaacagttcacgagggtcgaaaagattttgcatgcgacaagtgtaaAAAGAGattcggacaaaaatcggatttgttgaagcaccaaaaaacagtacatgaaggtcggaaagattacgcatgtgacaaatgtgagaaaaaatttggaagtaaatccGATTTGTataaacaccaaaaaataattcacgaaggtcgcaaagatttcgtatgCGATAAGTGTAGAAAAGAATTCGGATACAAACCAGCTTTGCTCTTACACCacaagacagttcacgaaggtcgcaaagatttcgcatgcgacaaatgcgagcagaaatttggacaaaattcAGATTTGTttaagcaccaaaagacagttcacgagggttga
Protein Sequence
MDKIKEKSDEIVSKDNLREHDNVVSDEKKHTCDICHETFTLKSSMMKHRDTIHNEQKVFACDKCEQKFEFRSHLSRHQISVHKSRKDYKFDQCEKKFVKKSSLFTHQKFVHKKREDFSCNKCERKFENKLILLKHNKIFHEVSKDYLCEKCAKRFNTKNNLLKHIKTVHEGCKDFACDKCEKKFGQNSDLFKHQKTVHEGRKDFACDKCEKKFGQKKYLLRHQKTVHEGRKDFTCDKCEKKFGQKCNLLTHQRMVHEGRKDYPCDKCEKKFGQRWIMIQHQKTVHEGRKDFACDKCKKRFGQKSDLLKHQKTVHEGRKDYACDKCEKKFGSKSDLYKHQKIIHEGRKDFVCDKCRKEFGYKPALLLHHKTVHEGRKDFACDKCEQKFGQNSDLFKHQKTVHEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-