Basic Information

Gene Symbol
-
Assembly
GCA_034770305.1
Location
JAPMIB010000003.1:102254-103962[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 5.2e-05 0.0019 19.3 5.8 1 23 133 156 133 157 0.95
2 13 4.5 1.6e+02 3.8 1.9 11 23 171 184 168 184 0.89
3 13 3.4e-07 1.2e-05 26.2 1.5 1 23 189 212 189 212 0.94
4 13 7e-05 0.0026 18.9 3.3 1 23 217 240 217 240 0.95
5 13 1.9e-06 7.1e-05 23.8 1.7 1 23 245 268 245 268 0.97
6 13 2e-06 7.4e-05 23.8 2.6 1 23 273 296 273 296 0.93
7 13 3.8e-07 1.4e-05 26.0 3.9 1 23 301 324 301 324 0.97
8 13 3.3e-07 1.2e-05 26.2 0.9 1 23 329 352 329 352 0.93
9 13 3.8e-07 1.4e-05 26.0 3.9 1 23 357 380 357 380 0.97
10 13 1.8e-07 6.7e-06 27.0 2.0 1 23 386 409 386 409 0.97
11 13 3.3e-06 0.00012 23.1 1.0 1 23 414 437 414 437 0.92
12 13 4.7e-06 0.00017 22.6 2.3 1 23 442 465 442 465 0.95
13 13 1.1e-05 0.00039 21.5 1.4 1 23 470 493 470 493 0.95

Sequence Information

Coding Sequence
ATGGAATTGACTGAAGAATTAAACGGTGCTGtcagGGTAAAAGTGGAACCTGAAGATGAGttaaattctgaaaataattttaatataatcaaTCTTAATACCAAAAATGTTCAGTCCGAAATCTTTCTGCGAAAGAATTCAGAAACAattcaTGTGCTTCAAAAATCTGACAAAACTTATGAAAGTGAGCTTGCTgatataaaaatcgaattcgAATGTAAAGACGAGAAGCTCAGTATAAATTCATTAGTAGacaataaaattgaagattattcacaaaaatgcttacagaatataaaatataacactGATTACAAACCTCTGACCACAGTTAAAATAGAAGCTATGGacgaagtgaaaaaagaattggACTTGAATTTCAACAATGAATGTATCTACGCATGTAAGACTTGTGAAAAAACATTTACCCGTAAAATTCATCTAAAGAGACACGTCAAATTATCGCATCATAGTATCAGCTATGCGTGTGatatatttgcaaaaaaacactcAAGGAACGTTAATCTTAAGAGACATATGGATTCGATGCATAAGGGTATTACCTACACCTGTGATACATGTGGGAAAACATTCTCACAAAAAGGTCATCTCAAAACCCACATCGAGGCTTTACATAATGGCATCACTCACGCCTGTAAAacatgtgagaagaaattctcAACAAAGAATTATCTTAAAATCCACATTGAGACGACGCACAATGGTATCCCCCACACCTGTGAAACATGTGGGAAGAACTTTGCAACgaaaagctctctctcacttcacATCAAGACTgtgcataatggtatcaccCACACCTGTACTACATGTGGgaagacattttcacaaaaaggtcatctcaaaatccacatcgaagCTTTGCATAATGGTATCCCCCACACCTGTGAAACATGTGGgaagacattttcacaaaaaggTCATCTCCAAATCCACATTAAGACTATGCATAAGGGTATCACCCACACATGTGGTACATGTGGgaagacattttcacaaaagagtaatctcaaaatccacattgAGGGTATACATAAAGGTATCACCCACACCTGTGAAACATGTGGgaagacattttcacaaaaaggTCATCTCCAAATCCACATTAAGACTATGCATAAGGGTATTATCACCCACACATGTGGTACATGTGGgaagacattttcacaaaagagtaatctcaaaattcacatcgaTACTATGCATAAAGGTATCACCCACACCTGTGAAACATGTGGgaagacattttcacaaaaaggttatctcaaaatccacatcgacgctttgcataatggtatcaccCACACCTGTAGTACATGTGGGAAAACATTTTCCCAAAAGGGTAAACTTAGAATCCACATCCAGGCTAAGCATGATGATATTACACATAAGTGCGatatatgtgaaaaaatattttcaaagcgATCTAACCTCATCCAACACGTCAAAGCGTCGCATATTGATGTAAAACTTGAATGTGATTATGTGGAAAATCGTCCGCATACAAGATTAGTCTCAAAACCCATATAA
Protein Sequence
MELTEELNGAVRVKVEPEDELNSENNFNIINLNTKNVQSEIFLRKNSETIHVLQKSDKTYESELADIKIEFECKDEKLSINSLVDNKIEDYSQKCLQNIKYNTDYKPLTTVKIEAMDEVKKELDLNFNNECIYACKTCEKTFTRKIHLKRHVKLSHHSISYACDIFAKKHSRNVNLKRHMDSMHKGITYTCDTCGKTFSQKGHLKTHIEALHNGITHACKTCEKKFSTKNYLKIHIETTHNGIPHTCETCGKNFATKSSLSLHIKTVHNGITHTCTTCGKTFSQKGHLKIHIEALHNGIPHTCETCGKTFSQKGHLQIHIKTMHKGITHTCGTCGKTFSQKSNLKIHIEGIHKGITHTCETCGKTFSQKGHLQIHIKTMHKGIITHTCGTCGKTFSQKSNLKIHIDTMHKGITHTCETCGKTFSQKGYLKIHIDALHNGITHTCSTCGKTFSQKGKLRIHIQAKHDDITHKCDICEKIFSKRSNLIQHVKASHIDVKLECDYVENRPHTRLVSKPI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-