Basic Information

Insect: Tribolium madens
Gene Symbol: -
Assembly: GCA_015345945.1
Location: JADDYM010000097.1:13958286-13960022[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.0028 0.19 12.2 2.2 1 23 46 69 46 69 0.97

2 16 0.36 24 5.6 0.5 1 23 116 139 116 139 0.95

3 16 5.1e-05 0.0034 17.7 1.1 1 23 148 171 148 171 0.94

4 16 1.2 80 4.0 5.9 1 23 179 202 179 202 0.94

5 16 0.034 2.3 8.8 3.8 1 23 211 234 211 234 0.97

6 16 0.0061 0.41 11.2 6.1 1 23 243 265 243 266 0.95

7 16 0.00012 0.0079 16.6 5.2 1 23 275 298 275 298 0.97

8 16 0.00048 0.032 14.7 2.6 1 23 309 332 309 332 0.97

9 16 0.22 15 6.3 3.0 2 23 341 362 340 362 0.97

10 16 1.4 97 3.7 7.7 1 23 367 390 367 390 0.94

11 16 0.88 59 4.4 0.5 1 21 398 418 398 421 0.84

12 16 0.031 2.1 9.0 4.1 1 23 429 452 429 452 0.96

13 16 0.036 2.4 8.7 4.4 1 23 461 483 461 484 0.95

14 16 0.0091 0.61 10.6 2.2 3 23 493 514 491 514 0.94

15 16 0.37 25 5.6 1.4 2 23 524 546 523 546 0.94

16 16 0.0024 0.16 12.4 2.3 1 23 555 578 555 578 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.0028	0.19	12.2	2.2	1	23	46	69	46	69	0.97
2	16	0.36	24	5.6	0.5	1	23	116	139	116	139	0.95
3	16	5.1e-05	0.0034	17.7	1.1	1	23	148	171	148	171	0.94
4	16	1.2	80	4.0	5.9	1	23	179	202	179	202	0.94
5	16	0.034	2.3	8.8	3.8	1	23	211	234	211	234	0.97
6	16	0.0061	0.41	11.2	6.1	1	23	243	265	243	266	0.95
7	16	0.00012	0.0079	16.6	5.2	1	23	275	298	275	298	0.97
8	16	0.00048	0.032	14.7	2.6	1	23	309	332	309	332	0.97
9	16	0.22	15	6.3	3.0	2	23	341	362	340	362	0.97
10	16	1.4	97	3.7	7.7	1	23	367	390	367	390	0.94
11	16	0.88	59	4.4	0.5	1	21	398	418	398	421	0.84
12	16	0.031	2.1	9.0	4.1	1	23	429	452	429	452	0.96
13	16	0.036	2.4	8.7	4.4	1	23	461	483	461	484	0.95
14	16	0.0091	0.61	10.6	2.2	3	23	493	514	491	514	0.94
15	16	0.37	25	5.6	1.4	2	23	524	546	523	546	0.94
16	16	0.0024	0.16	12.4	2.3	1	23	555	578	555	578	0.93

Sequence Information

Coding Sequence: ATGGAAGGAGTACAACAGCCCCCTTGTACGTGTCAATGGTGCGATTTTGTGACACTTCCAAGTTTGCTGAATCACCATTATGAGAAATGCCACGGTTCGCGTGAATTCAAGTGTGACCACAACCCCCCTGAAGCCTACTTCTGTAACTATTGCAATTACACCACCCAGTTTAAAGTAGCCTTAAACCAGCATGTGAAGACAACACACACCACTAACCCCCCACTTGATTACAATATAAAAAGCCACATTTGTAGTGTCTGCAATTTTGAAACATCCTCGATTTTATTATGGGTAAAACATGGCCTAGCCCCCACCGAATGTGGAAAAGAAATCACCAAGTCATGGTTCCAATGCGACTTCTGCGCCATCATCAAGAACCGTAAAGTGAACCTCGAGTACCACATCCTCAAGAACCACACCGATTCTGCGTGCATAAATTGGTTCAAATGCGAACAATGCGACTACAAGTCATTCCGTAAAGCGACTTTGAAACGTCACATGGCCATAATCCACGCCACTGAAGACACCCGTGTGCACCCATGCGGGTTTTGCCCCTATCGGGCACACACCAAACACACCCTCAAAGACCACATCAAATTCAAACACACGCCCCCTGAAGACATCCAATGGTACAAGTGCGACTATTGTTTGCACCAATCAAAAAGCAATCGTGAGTTGCGCGCGCACTTTCTCACCAAACACGCCCCTCCTGATGAAGTCACGTGGTATCAATGCACCCAATGCGACTACAAGACGAAACAAAAGCAACTCTTGCGCACGCACACTTATTATCATCATACTTCAAGTGATGAGATTAAGTGGTTTAAGTGCGAGGAGTGTGATTACAAGACTAAATACAAGCATAATTTGCGATTACACATGTCGAGGAGGCATTCAGCCGCGTTGTATGACACCGAACAGTGGTTTAAATGCCCTCAATGTGAGTTTAAAACACGCACAAATTTCCACTTGATGGATCATATTAATGTGCAACACTCGGGGGGCGAAGAAAAGTCACTCAAGTGTGATTTATGCCCGTTTCAAACCGACCATAAGTATTACATGGATCGGCATAGATCGACTCATGACATCAAGTGGCATCAGTGTCAAAAATGCAACTACAAAACTAAACTAAAAATGTGTCTCACTCAACACATCTATAATAAACACACCGAACTTGAAATCAAGTATTACAAATGCGAGTTTTGCTCGTATAAAACCCGAAATGGGGCGAAATTGCAGCCCCATATCGTGGAGAATCACTCCGATGCGAAGGAGGTGTATTTCAAATGCGAGCATTGTGATTATAAGACTAAATTGAAGGGGTTGATGAAGTCGCACACTATTCGAAAACATGCCCCACCTGAGGAAATCAAGTGGTTTAATTGCGATCAGTGTGATTATAAGGCCAGGATTAAGTTTAATTTGACCCAACATTTTAAGACTCATCATTCGAGTAATGAAAAGGAGTTTGGGTGTCCTTTGTGTGAGTTTAAGACGAATCGAAAGTATTATTTAAAAAGGCATCATTTGCTTATTCATGCCACTCCGGATGAGATAGAATGGGTCAAGTGTGAGTATTGTGATTATAGGTCGAAGGAAAGTCGCAGGATGAAGGGACATGTCAAGAGTAAACATTCGAATGTGGATGATGTGAAATTGTTCAAGTGTGAAAAGTGTGATTTTAGCACTAAGAGGCAGAGGGTTTTGGAAAGACATGAGAGTAATAAACATTGA
Protein Sequence: MEGVQQPPCTCQWCDFVTLPSLLNHHYEKCHGSREFKCDHNPPEAYFCNYCNYTTQFKVALNQHVKTTHTTNPPLDYNIKSHICSVCNFETSSILLWVKHGLAPTECGKEITKSWFQCDFCAIIKNRKVNLEYHILKNHTDSACINWFKCEQCDYKSFRKATLKRHMAIIHATEDTRVHPCGFCPYRAHTKHTLKDHIKFKHTPPEDIQWYKCDYCLHQSKSNRELRAHFLTKHAPPDEVTWYQCTQCDYKTKQKQLLRTHTYYHHTSSDEIKWFKCEECDYKTKYKHNLRLHMSRRHSAALYDTEQWFKCPQCEFKTRTNFHLMDHINVQHSGGEEKSLKCDLCPFQTDHKYYMDRHRSTHDIKWHQCQKCNYKTKLKMCLTQHIYNKHTELEIKYYKCEFCSYKTRNGAKLQPHIVENHSDAKEVYFKCEHCDYKTKLKGLMKSHTIRKHAPPEEIKWFNCDQCDYKARIKFNLTQHFKTHHSSNEKEFGCPLCEFKTNRKYYLKRHHLLIHATPDEIEWVKCEYCDYRSKESRRMKGHVKSKHSNVDDVKLFKCEKCDFSTKRQRVLERHESNKH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -