Tmad003756.1
Basic Information
- Insect
- Tribolium madens
- Gene Symbol
- -
- Assembly
- GCA_015345945.1
- Location
- JADDYM010000002.1:1049854-1052904[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00038 0.026 14.9 0.1 2 23 85 107 84 107 0.92 2 11 0.0099 0.67 10.5 4.6 2 23 187 209 187 209 0.91 3 11 5.6 3.7e+02 1.9 7.6 3 23 371 392 370 392 0.95 4 11 0.38 25 5.5 0.1 2 15 444 457 443 466 0.78 5 11 0.00042 0.028 14.8 1.8 2 23 528 550 527 550 0.96 6 11 0.15 10 6.8 0.2 2 23 575 597 574 597 0.92 7 11 0.0076 0.51 10.9 3.7 2 23 644 666 643 666 0.96 8 11 0.11 7.1 7.3 3.7 3 23 681 702 679 702 0.92 9 11 0.00023 0.016 15.6 0.6 2 23 751 773 751 773 0.95 10 11 0.27 18 6.0 0.2 1 23 841 863 841 863 0.98 11 11 0.011 0.75 10.3 0.3 2 23 873 895 872 895 0.91
Sequence Information
- Coding Sequence
- ATGATGACATCCGTCACGTTACCCTCAACTTCTGGTCCCTTACACGGCGGATACTCCTCAGTAGCCGAGGAAACAACAAGCAGCGAGCCCGAGTTCGAAACACCTCGTCCAGTGAAACGTTGTTTAGTAACACCACTAACCGATTCATGCAAGAAGCGGCGAAAACAATCGACACCAGTCCGAATTTCAGCAGCCGAATCCGACGTTCATATAGAAGGTAAGCCAAGTTCGACCTCTCCCGAGCCCGAGCTGCAGTGCCCTGTGTGCCAATTATACTTCACGAGTCCTGAGCAACTTCAAACTCATGTCGTATCTGAGCATTCTGCGCTCGAATGCAAGAAAGAACCGGAAGAATTCGCGCTGAATCCGTCAGAAAACAACGCAGCGGCGCACCAGGAGGTGCCATGGATGAACGAGCTGCAGGGCAAAGAGTGGATCAATCCGAGTTTGCACGGCTTGCCCTTCAACCCCACGAATCCGATGTTCATGACCTTACCTCAATTCGCGCAACCCGAGAACATGCCCAGACAACCGATTCGAATTTTCAATCCGGATGCGTATTGTGACTTGTGTAACAAGGAGTTTTGTAACAAGTATTTTTTGAAGACTCACAAAGCCAATAAGCATGGCATTTATTCCGATCCTCCCTCATCAGAGCCTCTAGTGAATAATGTAAATATTGCTTCGTATGCTGGAACAATTAAACTCCCAACTTCCGTGCCAAGTGTAGAAATATCAACTGTTAAAAGCGAAAAACCCGCCAATATTATCAATCCATTCAACAACTTGTTCCCCAATCCTTTCTCAAATAAATCCTTTCCGCAGAAAATCAAACCGAATCTCCCCAACTTATACGAAAGTGAATCAAATGAAAATGTTCCTAATTCAAATGGTTTCTCATCAAACTGTGAAAGTGATAAAGTATCGCCAGATGACCAACCAACTGAAGAATCTTCTAGTCCTAGAAATATACAAACCGAATCTACCTCATTTCAAAAAGATTCTGAAGGAGGAATCTACTACATTTCCCAAAGCAAAATGTCTCCAGGCAACGATATCGAAATATCCAATCGCCTCAAAAGAATCGGTGTTATGAATCCTAAAGCATTTTGTGAGATTTGTTGCAAGGAATATTGTAATAAATATTTCTTAAGAACCCATAAAATGAAACGTCACGGTATCTACATACCTGACGATAAAGATAGAGACACTAAACTCGAAGGAAGTGGCAATTTCCCATGGCAAAACAACATGCAAACAAGTCCTCTAAACTTAATAATGACAGAACAATCAAACCAAGATCGTAAAACTACCTCACCATCTGACATCAGTTGTGACATATGTGGAATCAAATTCCAAAACGCGAGTCTATCCCAACTACACAACGTGAGTGTTCATTCGAAAATGTACCCCAAAGAAGAGGAACACCAAGACCAACAACAAATCGGCGAAGAATCAAAAAAAGAAACGGCGACAACCCAAGAAAAACCAATAAACGCGGAAGCCATTAGCGAAGATTTGCAAAAACTACAAACAATGATTTTACAATTGAATGAACTCGACGTCAGTAAAGTATGCACGACTTGCAACGCTTGTAACAAAGAGTTTGAAAATCGTTATTTTTTACACGCCCACATGATGACAGAACATGGAATATTACTCGAAGACGTTACAGACGCTGATAAACCTGTTGAGTCAGAAAATAGCTCTAATAACAATACCATGTGTGATTTGTGTGGGAAAGACGTTCAAAATGTTGAAGAAATGAAAAAGCACTTGCTTGAATTCCATCCTAATCAACAAACCAGCACCGATAACAGCGTCAAAGACGAGTTTAACGGATTTAGCACTCCGGAAAAAAGCGTCAACAGGATACCTGTATCAAGTGCTGAGCGTCGAATTAGCATGAACGTGACACCGACTAGTAGTTATTGCGACATTTGCAATAAAGAGTTGTGTAATAAATATTTCATGAAGACGCACATGCAAAGAATGCATGGAATCGAGATCGAAAACGGCGCGCAAATTGGCGGTGTTATTTGCGATATATGCAATAAGGAGTTGTGCAGTAAATATTTCCTCAGAGTTCACAAGCACAATACTCATGGGATTGTCGAATACGGAACGAGTCTCCTCCAACCGAGGAAGAGCGAAGGCGAGACTGCTCACATGCCACCTGAACCGGATCCAGCACTAAAACCTGCAGATTTAGCCGATTTGAGTCATCGCTACTTCACTCATTTCACGGAAGTTTGCTCGATTTGTAGCCGACGTTTTCGCAGTACGAAATGGTTGAAGGCTCATTTATTGAGCGACCATGGCCAAGCCGGTGCCGAAAAATGGGCCGAATTAGAACAACAACTCCAACAGAGCATCGGTCAGCATTCGAAAACTGGGATTAAAAGTGAACGTAGCAGTCCCACATTGAAAATCCCAAACGGTGGCCAAGAACGTAAAGAAGTCGGGATTCAAAATGTCCTATCGAGTTTGTTCGGGGTTGACGAATCCAGTACAAAAACTTATTCATGTTCCTTTTGCCCTTTTACGACTCCTCTCCTTCCGCTACTATTCGTGCATGAAAGATCTCACACGATGTCATCGGATGGCGCACCTCTAAAATGCCCCGTGTGTGCCCAAAGCTTCCTGCAGCCAGAACTGTTGCAGCATCATATGTTTGCTCAACATCCGTTTCTTCCCTTACCGCCGTTCTTTAACGGAAACGAGAATCCTGGCGAGACGTCCAAGGAGCCGTCCGAGGGTGTCGCCGATGACGACGGTGACGCCGCCAAGAGTAAGAAGAAGGGAAAGGGGAAGAGGGCCGAGCTGTCGCCGGAAATCGGTCAAAGTCTGAAAGATGTTGCGAAAAGGGCGCAAGTTCCTGCTGCATACGCGTTGCCTCAGGGGGGCGAGGATGCGGGGTATGTGATGCAAGCGTTCCTGCTAGAGGAGGCTGCTCCCGAGAGGAGGCTCGTACCGGCCGTGGTGTTCCTGCCGGTGTTCCAAAAACAGCCCGCACCTCTCACCGTTACATTCACTCTCACCCCGGCCTAA
- Protein Sequence
- MMTSVTLPSTSGPLHGGYSSVAEETTSSEPEFETPRPVKRCLVTPLTDSCKKRRKQSTPVRISAAESDVHIEGKPSSTSPEPELQCPVCQLYFTSPEQLQTHVVSEHSALECKKEPEEFALNPSENNAAAHQEVPWMNELQGKEWINPSLHGLPFNPTNPMFMTLPQFAQPENMPRQPIRIFNPDAYCDLCNKEFCNKYFLKTHKANKHGIYSDPPSSEPLVNNVNIASYAGTIKLPTSVPSVEISTVKSEKPANIINPFNNLFPNPFSNKSFPQKIKPNLPNLYESESNENVPNSNGFSSNCESDKVSPDDQPTEESSSPRNIQTESTSFQKDSEGGIYYISQSKMSPGNDIEISNRLKRIGVMNPKAFCEICCKEYCNKYFLRTHKMKRHGIYIPDDKDRDTKLEGSGNFPWQNNMQTSPLNLIMTEQSNQDRKTTSPSDISCDICGIKFQNASLSQLHNVSVHSKMYPKEEEHQDQQQIGEESKKETATTQEKPINAEAISEDLQKLQTMILQLNELDVSKVCTTCNACNKEFENRYFLHAHMMTEHGILLEDVTDADKPVESENSSNNNTMCDLCGKDVQNVEEMKKHLLEFHPNQQTSTDNSVKDEFNGFSTPEKSVNRIPVSSAERRISMNVTPTSSYCDICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVICDICNKELCSKYFLRVHKHNTHGIVEYGTSLLQPRKSEGETAHMPPEPDPALKPADLADLSHRYFTHFTEVCSICSRRFRSTKWLKAHLLSDHGQAGAEKWAELEQQLQQSIGQHSKTGIKSERSSPTLKIPNGGQERKEVGIQNVLSSLFGVDESSTKTYSCSFCPFTTPLLPLLFVHERSHTMSSDGAPLKCPVCAQSFLQPELLQHHMFAQHPFLPLPPFFNGNENPGETSKEPSEGVADDDGDAAKSKKKGKGKRAELSPEIGQSLKDVAKRAQVPAAYALPQGGEDAGYVMQAFLLEEAAPERRLVPAVVFLPVFQKQPAPLTVTFTLTPA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00167920;
- 90% Identity
- iTF_00167920;
- 80% Identity
- -