Tmad000419.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tribolium madens
Gene Symbol
-
Assembly
GCA_015345945.1
Location
JADDYM010000096.1:4145122-4148245[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.093 6.3 7.4 3.6 1 23 301 323 301 323 0.96
2 13 0.1 7 7.3 0.5 1 22 327 350 327 353 0.90
3 13 0.053 3.5 8.2 5.8 1 23 394 417 394 417 0.93
4 13 3.3e-05 0.0022 18.3 0.6 1 23 423 445 423 445 0.96
5 13 2.9e-06 0.0002 21.6 2.0 1 23 459 482 459 482 0.96
6 13 1.5e-06 9.9e-05 22.6 2.9 1 23 488 510 488 510 0.98
7 13 0.00012 0.0079 16.6 4.4 1 23 516 539 516 539 0.98
8 13 4.6e-05 0.0031 17.9 1.9 3 23 547 567 547 567 0.99
9 13 2.4e-07 1.6e-05 25.0 1.4 1 23 573 595 573 595 0.99
10 13 2e-06 0.00013 22.1 4.7 1 23 601 623 601 623 0.99
11 13 0.23 15 6.2 9.8 1 23 629 651 629 651 0.98
12 13 1.8e-05 0.0012 19.1 0.3 1 23 657 679 657 679 0.98
13 13 6.3e-08 4.3e-06 26.9 0.8 1 23 685 707 685 707 0.99

Sequence Information

Coding Sequence
ATGGAGTTGACAGGCTTGATATGTGAAATGTCTCTTTGTCGATTGTGCGGTGAGGAAAATGTGAACGGAACTGAATTGTTTCCTACAAGAGAAAACGAACCAGATTTAAGTCAACTCGTTAACAGATACTTACCATTAAAGATCGAGAATGACCGAAAGTTTCCAACTAAAATTTGCCCAGGTTGTAACATCCAATTGGAAGCGACGAAATCGTTCATGGACTTGATAGTCCAAGGCCAAATAAAACTGAGACAATTGTATAAATTGCAACAAGACAAATTGTATCGACAAGAAAAGCAGAGACTACAACTTGAGGAAGCTTTGAAGAGTGTTAATCCCAGTTCAAGCGTGGATACTTACACCATACAGTCTGATGAGACTGGAGAGAAATTTTTAATACAAATTTTTTCACAAGGACCCTTATTTCCTCCTGAACATGAATTGTCATTAAAGGCTGAGGGTCTTACTAGACCTAGAAGGAAACGTGGTAGACCGCCAAAACCTCCACAACCGCCCAATACAGAAGACCAACTTTTAAAAGCAAATGAAAAAGATAATACTAAAGTTGATGAGAAAATAGACCAATTTGAAGAAACTACAGAAGACGGTAAAAGAAAACGAAGAATTAAAGTCCCAACGAGATACTCTGAGGCAATTCAAGGGAAAGAATTAGATAAAGTTTTTAAACAGGAAGGCGTAATAGATGAAGAATCTGTATCAGATGAAGATGGTACAATTTTAGAAGAAGGGGAAAACTCAAATAAAGTTGAAGAAGTAATTGGACGTCTTGAGACCGAAAACGGTGAAGATTTGGGCCAACCAGTTATCATAAATAAAACTTTGAATAAAACGCGCCCTAGAAATAAAAGTATAGCGGGACAATCAAAAAGACGACGAAAATACCAGTGTGATATTTGTGGTCGCGAATTTTTACACCATGGGAGATACGAATTACACAAAAAAATGCACGACGTGGAATACAACTGCACTCAAGATGGCTGTAGTTTTACAACGGATAAAAAGTCGCTTTTGGAGCAACACCAGCAGGAAAGTGTCCACTCTGGTCACACAGTGTCGGAAAAAGTTGATAAATATGGGACTATCCAGCTGCCTACAGACCTCAAGCCCAGCCAAGCGTCAAAGCTCGAGCAGCCTCCTCCCCCCGCCCCCAAAAAGGAGTTCACTTGCGAAAACTGCCACAAGTCCTTTTCCTGCAAACAGAATTACGAGGTCCACTTCAAGGCCGTCCATGCCGGTGAGCGCCCCTTCGCTTGCGAACTATGCAACAAGCGCTTTTCGTACGCCAACAGCCTCAAAGTCCACCTTCTGCAACACTTCCCTAAAACAGGTCCCGACGACGACTCCAGTGCCCAGTACAAGTGCCCCTCGTGTCCCAAGAGCTTTCGGCATCCCAGCAGTCTGCAGTACCACCGCGACTCGGAGCATACCAACGGCCGACGCTTCGTCTGCAACAAATGCGACAAGCCGTTCAAGCACCGCCAGCTGCTCCAACGCCACCAACTTGTGCATTCCGACGAGAGGCCTCATCGGTGCTCTCAGTGCAACTCCGCGTTCAAAACGCGGGCTAACCTCATTCACCACACCAGGACGGTGCATTCCGGGCAACGCAGCCATTGGTGCTCGCAGTGCGATAAGGCCTTCGCACATAAAACCGCCCTCAAGCTGCATCAGAGGTGGCATTCGGGGGTGAGGCCCTACCAGTGCGAGTTTTGCAAGAAGTCGTTCTCGCAGAAGGGGAATTTGGCGGAACATAGGAGGATACATACGGGGGAAAAACCCTACCAGTGTGATCACTGTGGAAGGGCTTTCACGACTTCGTCGCAGTTTAGACTTCACAAGAAACGACATTTGGATGAAAGGCCCCACAGGTGCGAGTATTGTCAAAAAAGTTTTCTACATAAGGTCACTTTGAGGTGTCATATGAGACGGCATTTTGACGAGAGGCCATTCAAGTGTCAACAGTGTCCCAAGACGTTCCCTGAAGCTTGGGCTTTGAAAAAACATGAGAGGTTACACACGGGGGAAAAGCCCTATAAGTGTGACTTGTGTTCTAAAGCCTTCGCGGATAGTTCGAATTTGGCCAAGCATCGACGAACTCACAGGAATTTGAAAGACAAACAAATGCTTTTTGTCACGTATGAAAAAGACGGTGGTGATGCTATTGTTACGTATATAGAACCACAAGATACAGTGGTCGAAACAAACGAAATAATTAACGTCGCTGAAGAAATAGACGGTGTCAAAACGATACAATTGCAACAACTTGTCGATCAGGAAGGTAACCCTATTAGTTTTATTACCCAAGATGGGCAACAAGTTAAGGTTGTTACAAGTAACGAGGATGGGCAAGAAAACATCCAAGGGTTACTCCCTGATGGCACGTTGGTACCAATTAGTTTGACAACGGTACCGGAGAAAAATAAACCAATACTGACTCAAATCGAGGATACTCAGAAAACTATTGACGTCCCAATTGAAGGTCAGTTATTATCAAGCAGCATACAATTCCTCTCTGATGACGATCCAAAAGTGGACAATAACATTCAATTCGTAGCTGAAGATAATCAAAATATGTGTTTAGTAACAACGTACAACATTGAAGATTCTATAAATCCGCAATATCTTAGTATGCCCTAA
Protein Sequence
MELTGLICEMSLCRLCGEENVNGTELFPTRENEPDLSQLVNRYLPLKIENDRKFPTKICPGCNIQLEATKSFMDLIVQGQIKLRQLYKLQQDKLYRQEKQRLQLEEALKSVNPSSSVDTYTIQSDETGEKFLIQIFSQGPLFPPEHELSLKAEGLTRPRRKRGRPPKPPQPPNTEDQLLKANEKDNTKVDEKIDQFEETTEDGKRKRRIKVPTRYSEAIQGKELDKVFKQEGVIDEESVSDEDGTILEEGENSNKVEEVIGRLETENGEDLGQPVIINKTLNKTRPRNKSIAGQSKRRRKYQCDICGREFLHHGRYELHKKMHDVEYNCTQDGCSFTTDKKSLLEQHQQESVHSGHTVSEKVDKYGTIQLPTDLKPSQASKLEQPPPPAPKKEFTCENCHKSFSCKQNYEVHFKAVHAGERPFACELCNKRFSYANSLKVHLLQHFPKTGPDDDSSAQYKCPSCPKSFRHPSSLQYHRDSEHTNGRRFVCNKCDKPFKHRQLLQRHQLVHSDERPHRCSQCNSAFKTRANLIHHTRTVHSGQRSHWCSQCDKAFAHKTALKLHQRWHSGVRPYQCEFCKKSFSQKGNLAEHRRIHTGEKPYQCDHCGRAFTTSSQFRLHKKRHLDERPHRCEYCQKSFLHKVTLRCHMRRHFDERPFKCQQCPKTFPEAWALKKHERLHTGEKPYKCDLCSKAFADSSNLAKHRRTHRNLKDKQMLFVTYEKDGGDAIVTYIEPQDTVVETNEIINVAEEIDGVKTIQLQQLVDQEGNPISFITQDGQQVKVVTSNEDGQENIQGLLPDGTLVPISLTTVPEKNKPILTQIEDTQKTIDVPIEGQLLSSSIQFLSDDDPKVDNNIQFVAEDNQNMCLVTTYNIEDSINPQYLSMP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01480318;
90% Identity
iTF_01480318;
80% Identity
-