Basic Information

Insect: Tribolium madens
Gene Symbol: ZFX
Assembly: GCA_015345945.1
Location: JADDYM010000011.1:3395495-3397625[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 4.7e-07 3.2e-05 24.1 0.4 1 21 8 28 8 28 0.97

2 21 0.00018 0.012 16.0 0.9 1 23 47 69 47 69 0.98

3 21 2e-05 0.0013 19.0 0.3 1 23 74 97 74 97 0.96

4 21 0.016 1.1 9.9 1.4 3 23 105 125 104 126 0.95

5 21 0.00055 0.037 14.5 0.1 1 23 132 155 132 155 0.95

6 21 0.00012 0.0078 16.6 1.5 2 23 161 182 160 182 0.96

7 21 0.01 0.68 10.5 6.6 1 23 191 213 191 213 0.99

8 21 0.00033 0.022 15.2 1.6 1 23 220 242 220 242 0.99

9 21 1.8e-05 0.0012 19.1 0.7 1 23 248 270 248 270 0.97

10 21 2.7e-07 1.8e-05 24.9 1.6 1 23 276 298 276 298 0.99

11 21 4.2 2.8e+02 2.2 1.1 1 8 304 311 304 312 0.93

12 21 1.9e-07 1.3e-05 25.3 1.0 2 23 321 342 320 342 0.96

13 21 0.0015 0.1 13.1 5.9 1 23 347 370 347 370 0.94

14 21 0.0003 0.02 15.3 0.7 3 23 378 398 377 399 0.95

15 21 0.097 6.5 7.4 0.3 1 23 405 428 405 428 0.96

16 21 0.0016 0.1 13.0 0.4 2 23 434 455 433 455 0.96

17 21 0.00011 0.0073 16.7 0.4 1 23 464 486 464 486 0.98

18 21 0.00073 0.049 14.1 0.3 1 23 492 514 492 514 0.98

19 21 3.3e-07 2.2e-05 24.6 0.4 1 23 520 542 520 542 0.98

20 21 1.8e-08 1.2e-06 28.5 0.6 1 23 548 570 548 570 0.99

21 21 0.0091 0.61 10.6 3.2 1 21 576 596 576 597 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	4.7e-07	3.2e-05	24.1	0.4	1	21	8	28	8	28	0.97
2	21	0.00018	0.012	16.0	0.9	1	23	47	69	47	69	0.98
3	21	2e-05	0.0013	19.0	0.3	1	23	74	97	74	97	0.96
4	21	0.016	1.1	9.9	1.4	3	23	105	125	104	126	0.95
5	21	0.00055	0.037	14.5	0.1	1	23	132	155	132	155	0.95
6	21	0.00012	0.0078	16.6	1.5	2	23	161	182	160	182	0.96
7	21	0.01	0.68	10.5	6.6	1	23	191	213	191	213	0.99
8	21	0.00033	0.022	15.2	1.6	1	23	220	242	220	242	0.99
9	21	1.8e-05	0.0012	19.1	0.7	1	23	248	270	248	270	0.97
10	21	2.7e-07	1.8e-05	24.9	1.6	1	23	276	298	276	298	0.99
11	21	4.2	2.8e+02	2.2	1.1	1	8	304	311	304	312	0.93
12	21	1.9e-07	1.3e-05	25.3	1.0	2	23	321	342	320	342	0.96
13	21	0.0015	0.1	13.1	5.9	1	23	347	370	347	370	0.94
14	21	0.0003	0.02	15.3	0.7	3	23	378	398	377	399	0.95
15	21	0.097	6.5	7.4	0.3	1	23	405	428	405	428	0.96
16	21	0.0016	0.1	13.0	0.4	2	23	434	455	433	455	0.96
17	21	0.00011	0.0073	16.7	0.4	1	23	464	486	464	486	0.98
18	21	0.00073	0.049	14.1	0.3	1	23	492	514	492	514	0.98
19	21	3.3e-07	2.2e-05	24.6	0.4	1	23	520	542	520	542	0.98
20	21	1.8e-08	1.2e-06	28.5	0.6	1	23	548	570	548	570	0.99
21	21	0.0091	0.61	10.6	3.2	1	21	576	596	576	597	0.94

Sequence Information

Coding Sequence: ATGCATACGAAGGAGAAACTCTATAAATGTACAGAGTGTGATAAGTCATTTTCGCAAAGTGGCAGCTTGAAAATCCACGTCCGGTGTCGTTCTGGAGAAAGACCAATCCTATACATCTTTGCTGCTCCTCGAAGTTCGTATCAGTGCGAAGTCTGTTTCAAAATCTACCCTTCTAATAATTTGCTACGCAGACATAGTCTGCGCCATAGAGAGAAAAAATTCAAGTGTCCTCAATGCGATTTGATGTTTATTTTACCATCGGAACTAAACAAGCATGTGCAATACCAGCATGACAAAATCTTACGTGCCTTTTGCGATCTTTGCGACTACGCAACGCAGGATAAAACCCGACTTCAGATTCACATGATTCGCCACCACACGAGAGATTTTCCCTTTAAATGCGATGTTTGCGGACAGGGTTTTATGAGTCGAGGAGATGTGATTAGGCACAAAGAGATCCAACACGAAGGTGTTGTATTAGTGTGTCAGTTTTGTCAGAAAACTTTCAAAGATCGAGATTATTTTCGTCTGCATGTGATACGACACGATCCTGAATACGTCGCTACTGCGTATACGTGTCAGGAGTGTTTCAAAGTGATGCACACGAAGCAGAGTTTTAAAAGACATATGAAGAAGCATGCATTTCCAATGGAGAGTTATGTGTGCGATYTTTGTGGTAAAAGTCTAATGACGATGCAAACTTTAAAGAATCATAAGAAGACACATTCAGGGGAAAAGAAACATATTTGTGAAGTGTGTGGCAAASGGTTTACTTTGAGAAAAATGCTAGTGGAACATATAAGAGTGCATACGAAGGAAAAACCATATGTTTGTGTTCACTGTCAGAAGGGGTTTTCTCAGAAAGGCAGTCTTAATATTCACATGCGGTCGCACACTGGTGAAAGGCCCTACAAGTGTGAAGTGTGCAATAAGCAATGGTTTTTGGACGAAAATCAGCTCGAATGCAAAATTTGCGATAAAACATTTTCAACTAAAGACAAACTCACCAGACATGTCGCTAGACACAAAGATAAAAAACACAAGTGTCTCAAATGCGACAAAAAATTTCACACAAAAGCTGAATTAAAAATCCACACAAGCAACCGGCATGAAAGTCTGGGAGAACGAATATGTTCCATTTGCAATTACCAAACAATCACAAAAGTGGATCTTAAAAGACACATAATTGTTCATCACACTAGAGACTTTCCGTTCAGATGTGATTTGTGTCTTAAAGGTTTTATGGCTAAGGGACCTTTGGCTCATCATAAGAATGTCGTTCATGAAGGAATGCGCTTGGTTTGTCCGGTTTGCTCCCAAATACTCAGAGACCCTTTCAACTTTCGGCACCACCTGGCTCGGCATGACCCCAACCACATTGAGGAAAAATTTACCTGCAAGGAGTGTTTTAAAGTGTTGGGGAGTGCCAACGGGTTGAGGAATCACATGAAAGTGCACAGTGAAGGTGCAGGTTATGTTTGTGATGTGTGTGGAAAGACTCTCTCGGCTTTACAGACTTTCAAAGATCATAGAAAAATACATACAGGTGAAAAGAATTTTGTGTGTGAAGTGTGCGGGAAGGCTTTTAATAAGAGACAATTACTCAAGACTCATATCAGAGTGCATACGAAAGAGAAGCCTTATAAGTGTGTCGAATGTGGCAAAGCGTTTACGCAGAAAGGGTCTCTTACTATCCATATGCGGTACCATACGGATGAAAGACCCTACAAGTGTGATCTGTGCTCGAAACAATTCATTACGAAAACTGTCCTTAACAGTCATAAATGTAAAGGCGCTGTATAA
Protein Sequence: MHTKEKLYKCTECDKSFSQSGSLKIHVRCRSGERPILYIFAAPRSSYQCEVCFKIYPSNNLLRRHSLRHREKKFKCPQCDLMFILPSELNKHVQYQHDKILRAFCDLCDYATQDKTRLQIHMIRHHTRDFPFKCDVCGQGFMSRGDVIRHKEIQHEGVVLVCQFCQKTFKDRDYFRLHVIRHDPEYVATAYTCQECFKVMHTKQSFKRHMKKHAFPMESYVCDXCGKSLMTMQTLKNHKKTHSGEKKHICEVCGKXFTLRKMLVEHIRVHTKEKPYVCVHCQKGFSQKGSLNIHMRSHTGERPYKCEVCNKQWFLDENQLECKICDKTFSTKDKLTRHVARHKDKKHKCLKCDKKFHTKAELKIHTSNRHESLGERICSICNYQTITKVDLKRHIIVHHTRDFPFRCDLCLKGFMAKGPLAHHKNVVHEGMRLVCPVCSQILRDPFNFRHHLARHDPNHIEEKFTCKECFKVLGSANGLRNHMKVHSEGAGYVCDVCGKTLSALQTFKDHRKIHTGEKNFVCEVCGKAFNKRQLLKTHIRVHTKEKPYKCVECGKAFTQKGSLTIHMRYHTDERPYKCDLCSKQFITKTVLNSHKCKGAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -