Basic Information

Insect: Tribolium castaneum
Gene Symbol: ZFY
Assembly: GCA_000002335.3
Location: NC:4119126-4138310[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.86 51 4.1 4.3 1 22 531 552 531 555 0.90

2 13 4 2.4e+02 2.0 0.5 2 19 612 629 611 635 0.83

3 13 0.00011 0.0067 16.3 1.4 1 23 647 670 647 670 0.96

4 13 8.1e-05 0.0048 16.8 1.2 1 23 675 699 675 699 0.93

5 13 0.0033 0.19 11.7 0.3 2 21 713 732 713 735 0.90

6 13 0.00056 0.033 14.2 0.1 2 22 741 761 741 761 0.96

7 13 0.027 1.6 8.9 0.2 1 23 816 837 816 837 0.93

8 13 4.3e-05 0.0025 17.7 0.4 1 23 843 865 843 865 0.98

9 13 0.00031 0.018 15.0 1.2 1 23 887 909 887 909 0.95

10 13 5.2 3.1e+02 1.7 0.9 2 23 915 938 914 938 0.80

11 13 0.0008 0.047 13.7 3.0 1 23 944 966 944 966 0.97

12 13 0.0023 0.14 12.2 2.8 1 23 972 994 972 994 0.97

13 13 0.0026 0.15 12.1 1.7 1 20 1000 1019 1000 1021 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.86	51	4.1	4.3	1	22	531	552	531	555	0.90
2	13	4	2.4e+02	2.0	0.5	2	19	612	629	611	635	0.83
3	13	0.00011	0.0067	16.3	1.4	1	23	647	670	647	670	0.96
4	13	8.1e-05	0.0048	16.8	1.2	1	23	675	699	675	699	0.93
5	13	0.0033	0.19	11.7	0.3	2	21	713	732	713	735	0.90
6	13	0.00056	0.033	14.2	0.1	2	22	741	761	741	761	0.96
7	13	0.027	1.6	8.9	0.2	1	23	816	837	816	837	0.93
8	13	4.3e-05	0.0025	17.7	0.4	1	23	843	865	843	865	0.98
9	13	0.00031	0.018	15.0	1.2	1	23	887	909	887	909	0.95
10	13	5.2	3.1e+02	1.7	0.9	2	23	915	938	914	938	0.80
11	13	0.0008	0.047	13.7	3.0	1	23	944	966	944	966	0.97
12	13	0.0023	0.14	12.2	2.8	1	23	972	994	972	994	0.97
13	13	0.0026	0.15	12.1	1.7	1	20	1000	1019	1000	1021	0.95

Sequence Information

Coding Sequence: ATGTGTGCGGGAATTTGCTTAGAAGCGAGGGTGCGGAATTTTGCCGACGATACTTTTGAAAAGTTTCAGCGTCATGTAGACATGATTAAAAATTATTATTTAGGGTCAGCGTGGAATCCACCACCGTTCTATCAAGTTTCAAGTCGGCACTGCACTGCAGAAATGATCGGCGATTTCGACGACGACACGCACTTCTGCCTAAAATGCCACTCCACCATCATAGGACTCGACAATTACGTCAACCATCGAAAAACAGGATGTCCCAAAAACGTCGTAGACCTACCAAAATCACCACTACCCAGCCAACTCCTACCACCCGACGATTCCTTCAATTTAAAAGCGGACGATTTTTTTTCGTCCCTAGAGCTGCAAAGTAGCACCAAAAAACTAACACCGTCAAGCACCGGCAAAAACTTTAGTGGGATTTTAACCCGAAGTAAAACCACAGCAGTAATACAAGCATCGACTTCGCAAAAGGAAACCCAAGAGATTCCCCAATCCAAGTCGGGCAAAAATGTCTGGATTGGGGGACACCAACTGAAACTGGGTTACGGCGACAACCAATCAAAATTGATCAAAGCTGTCGATAACCTAGAAAGACGTAAGGAAGACCCCCCGAAAATAAGCGTCTACGAAGACAGTGACGTCGAATCTGAAGATTATGACTACGATGTTGACGAATCTTCAGACGAAGATAATCATGATGCGCCCCCTAGAAACCACACCGGGGGCAAATGGAAACCTTCGTCCCCAATTCAGTGGCAGAGGCCTCAAGAATGGAGCGTCCCCCCTCCCACTTACACGGGGGGCAAGTGGAAACCGCCACTAAAACGAAACTCGCCACCCCCTTCGCACACCAAGGGCAAATGGAAGCCGTCATACCCCCTCTCACCGAAGGAAACTTACGATTTTCCTCCCCCAAGCTTCACTGGGAGTAAATGGAGCCAGTCTAAGGCCAGGCAAGACTTTACTGCACCTCCTTCAAACCACACGAAGGGAAAGTGGAAACCTGACGATGAGCCCAAAATTGAGACTCTCAAAACTAAGGGCAAGGCCAAGAAAGAGACTGAGATTCTTCCGCCCACTTACACCAGCGGCAAATGGAAGCCGTCAACTATCACAGATCCTTCCCCCAGCTATACTAAGGGGAAGTGGATCCCTCCTGACGAAACTAAGAAAAGTCCGACTAAAATAACCGATGATTCGCCTTTTCGCAAGTCGAGTGGCACGGTACAGTACTGGTGCCGGCCTTGCAATCGCAGATTGGCGTCAAAAATTGTGTACGAGAGGCACTTAAAATCGGAATTGCACTTTAAAAGGACTCTCCACGATAAGGATTTTGACGATAACGTCGGGATGATTGAAAAACGCGTCAAAAAGAAAACAGGAACTGAGCCAAACCCTGCTGCCAAAAAACGCAAACGCAAGAAAATTTTCATCAAGTGCGAGGTGTGTAACTCCAAAGTTAACACACTCCTGATGGGGAAACACCTGATTTCGCACTACCACTGCCGCAAAGGTGATATTACAACTCCGGTGGCGCAAGCCATGATTCTTGACAACATCTCCGCCATAATCCTCCAAAGTCCCTACCAGTGTGGCCTTTGCAAATTTTACTTCAACCACCATAAGGATTTCCTGGAGCACTGGCTCTCGGAGTATCACTGGGTGAGGGCCGACTCTGGCAGCGGCTATTTCTGGTGTTCGTTTTGCAAATTCAAGGATGCAAATAGTGCGACAATGTATGCGCACCTCATCTCAGAGGAGCACGAGGTTGTGGTGTCGGTCATAAACAGATCAGTGCCCATAATTGTGAAAAAGGTCAATCCGGTGAAATGTGAGGAGTGCAACGAGGAGTTTTTACTAAACGTTGCTTTAATGAAACATTGCCAGAGAGAGGGACACACTTCGCAAAATCTGACCCAAGTCATGAATAATTTTAACTGTTTGAAGTGCCAACAAGTGTTCCGGTCGAATATTTTGTTGAAAAGGCACAAACGGATTGTGCACGGCGACCATGTTTTTGTCTGTACGATTTGCAACAAGAACTTTACCAGGAAAGAAGATGCAAAAATGCACAGGAATACGAGTGAACATAGATATAAAGTTTTAAATAGGAAAAAGGGCCAACAACGGAAATGTGACTACTGTAACGAAATTTTTGCCAGTTTGGGCGACTTCAAGCAACATCTCGGTGACAAGCATAAGGAATTTAGCCCCAGATGTAGCCAGTGTGGGGCCACTTTCACTTTACCTCAAGAACTTACTGTTCATTTACGGACCAAATCATGCGCTTATAAGGAAAATTTTGACAGTGCTAACTCTTGTGATAAGTGCACTTTTTCGTCAAGTTCCACGTCCGAGCTGCTTTTCCACAAGGTTCTTCACAGCGAGCCGGCTTTAATGGTGATGGCATCGGACCCAAAAAAGAAGCCTTTGGCACAGTACAAGTGCCCACTTTGTGACAGATTGTTCGTAAAAGCTTCGCTACAGCCCCACTTAAGACTACATACGAAGGAACGGCCCTTTGTATGCTCGATTTGTTCGAAAGGGTTCGTCAGGAAGAACAATTGGATGCTGCATGTGAGAAATCACGAAAGGAAGGGCGTAAAGAAGTTGCAGGAGGAGAAGAAGCGGGAAGTGTCAGGCGATCGCCCTTTTTTGTGCTCGACCTGTGGAGCCAGCTTCAGGAAAAAATCGATCCTGCAACAGCACATGACCACACATTCGGGCAAATTATGCAAATGCCCGAAATCGGGCTGTATTTTCGCCGCCCGCAGCATGGGCGAGTTGAAGCAGCATTTCCGGACGCATTCCGACGTGAAAAGCTTCTCTTGCAGCATTTGCGACTACCGCGGAAAGACCAAACAGCAGTTAAAACACCACTTGACCGTCCACAGTGGGACGAAGAAGTATGCTTGCACCAAGTGCTTGTTCTCGGCGAGGACGATGTCTCATTTGAAGAGACATATCCGCCTACACACCGGCTCCAAGCCCTACAGTTGCCCCCACTGCGCCTACAAATGCAACACTTTGGAAAATCTGAGAAAACATGTACTGTTGACCAATAAACACCGAGGGAAGTGTATTTACGAATGCAAGTTCTGTGCAGAGTCGCCCTTCCAAAGCAACTTTGCCAAAGAATTTAAGGTTCATCTTGTTACCGAGCATTCAGCAATGTTTAAAAGTGGACGGGAAGCTGCTACTTTTGTTGCAGGAATTTATGACGAGCAGAACGATTGCACCGAATTTAATCCTGCAAGCTCCGAGGACGACGAATCGAAGCCTACAAATGCAAAAGACCGGTCGGCTCCGCCGAAGGTGATAATCCTGCAGCACTTGAAGAGCGAGGTGGACAAAGATCCCGTGGTGGCTTCGAGCAGTAAAGACACGGGTGAAGAAGGCAATCCTGACGAGATGTTGCCGATGTTTATTGTGTCTCGCGATGAGACAGTTTCAGTAGATAATCTCACGGAGACTTGGAATGTGGTCGGTAGCTACGACGTTGAAGAGTCCGGAGCGTTAGTTCCTTTCAATAGCGATAACGTTCTCTTCCAGGGACATTTCTGA
Protein Sequence: MCAGICLEARVRNFADDTFEKFQRHVDMIKNYYLGSAWNPPPFYQVSSRHCTAEMIGDFDDDTHFCLKCHSTIIGLDNYVNHRKTGCPKNVVDLPKSPLPSQLLPPDDSFNLKADDFFSSLELQSSTKKLTPSSTGKNFSGILTRSKTTAVIQASTSQKETQEIPQSKSGKNVWIGGHQLKLGYGDNQSKLIKAVDNLERRKEDPPKISVYEDSDVESEDYDYDVDESSDEDNHDAPPRNHTGGKWKPSSPIQWQRPQEWSVPPPTYTGGKWKPPLKRNSPPPSHTKGKWKPSYPLSPKETYDFPPPSFTGSKWSQSKARQDFTAPPSNHTKGKWKPDDEPKIETLKTKGKAKKETEILPPTYTSGKWKPSTITDPSPSYTKGKWIPPDETKKSPTKITDDSPFRKSSGTVQYWCRPCNRRLASKIVYERHLKSELHFKRTLHDKDFDDNVGMIEKRVKKKTGTEPNPAAKKRKRKKIFIKCEVCNSKVNTLLMGKHLISHYHCRKGDITTPVAQAMILDNISAIILQSPYQCGLCKFYFNHHKDFLEHWLSEYHWVRADSGSGYFWCSFCKFKDANSATMYAHLISEEHEVVVSVINRSVPIIVKKVNPVKCEECNEEFLLNVALMKHCQREGHTSQNLTQVMNNFNCLKCQQVFRSNILLKRHKRIVHGDHVFVCTICNKNFTRKEDAKMHRNTSEHRYKVLNRKKGQQRKCDYCNEIFASLGDFKQHLGDKHKEFSPRCSQCGATFTLPQELTVHLRTKSCAYKENFDSANSCDKCTFSSSSTSELLFHKVLHSEPALMVMASDPKKKPLAQYKCPLCDRLFVKASLQPHLRLHTKERPFVCSICSKGFVRKNNWMLHVRNHERKGVKKLQEEKKREVSGDRPFLCSTCGASFRKKSILQQHMTTHSGKLCKCPKSGCIFAARSMGELKQHFRTHSDVKSFSCSICDYRGKTKQQLKHHLTVHSGTKKYACTKCLFSARTMSHLKRHIRLHTGSKPYSCPHCAYKCNTLENLRKHVLLTNKHRGKCIYECKFCAESPFQSNFAKEFKVHLVTEHSAMFKSGREAATFVAGIYDEQNDCTEFNPASSEDDESKPTNAKDRSAPPKVIILQHLKSEVDKDPVVASSSKDTGEEGNPDEMLPMFIVSRDETVSVDNLTETWNVVGSYDVEESGALVPFNSDNVLFQGHF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -