Basic Information

Insect: Tribolium castaneum
Gene Symbol: BCL11A
Assembly: GCA_000002335.3
Location: NC:9048758-9060714[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 3.1 1.8e+02 2.4 0.1 2 11 33 42 32 45 0.86

2 7 2.4 1.4e+02 2.7 1.8 1 23 192 215 192 215 0.94

3 7 1.2e-06 7.2e-05 22.5 2.8 1 23 483 505 483 505 0.96

4 7 8.1e-06 0.00048 20.0 4.4 1 23 511 533 511 533 0.99

5 7 5.7e-07 3.4e-05 23.6 3.2 2 23 725 746 724 746 0.97

6 7 7.5e-06 0.00044 20.1 3.3 1 23 752 774 752 774 0.99

7 7 4.8e-05 0.0028 17.5 0.4 1 22 782 803 782 803 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	3.1	1.8e+02	2.4	0.1	2	11	33	42	32	45	0.86
2	7	2.4	1.4e+02	2.7	1.8	1	23	192	215	192	215	0.94
3	7	1.2e-06	7.2e-05	22.5	2.8	1	23	483	505	483	505	0.96
4	7	8.1e-06	0.00048	20.0	4.4	1	23	511	533	511	533	0.99
5	7	5.7e-07	3.4e-05	23.6	3.2	2	23	725	746	724	746	0.97
6	7	7.5e-06	0.00044	20.1	3.3	1	23	752	774	752	774	0.99
7	7	4.8e-05	0.0028	17.5	0.4	1	22	782	803	782	803	0.97

Sequence Information

Coding Sequence: ATGACGGTTGAACTACTTTTAAAAATGAAACTCTTTTGGAAGTATTTCATAGCAGACGCAGACGGGGCGGGCACAGACACCCACCAGGACATCCTGACTTGCGGCGTGTGCCAGAAGCCTTTCGCCCTCTCCGACATCGTCCGCTTCATCCAGCACAAAGTAGCGTCTTGCAACAAAGAAAACTTCGGACAATGTTTCGCCGCCACCGACCGAGAACGAGACAACGACGACGGGGCACTGCCCCTTTCCACCATCAACACCCGCCGGCCGAGCATCTCGGCCCCCATCTCGGGGAAAAAGGCGTCTGGGAACAGGGTGCACACTCCGCCGCCAGCCTCCCCCAGACTGCCGGCACCTGGCGATCTGTGCGTCGACGGCGCCGCCTCCTCCACCCCCAAGCGGAGGGCCTCGGCGTCGCCGCTCACCTCCTCCAGCATGGAGGACGGCGAGGACATCAAGCCCGACATCAAGCAGGAGCGGATGGACACCACGGAGGAGAGCAGCCAGTGCAAGAAATCGCGAACGGAGTTCGCAGACGCCGAGTCCAACACTACTCATAGTGAACCGAGTAACTACGTTTGTTCAACGTGCAAAGCGAGGCTGCACTCGGCCTGGCGCCTAATCCAGCACGTCCAGCACTCCCATGGAATCAAAATCTACATCGAAAGCTCCCCCACCAGCAGCAAGAACAACAACCACAGTACGAGCAGTGCTAGTAGTAGCTCGTCGGGATGCTCCTCTGGCGGGCCTCCGCCGCCGCCCAGTATGCGCCACCACTTGCTGCCGCCCCCCGACTTGCACAACCCCTTTGGTGTTGGCGGTTTGCTGCGGTTACCGCTCCCGCCACTTAACCACGGTCCAGTTCCTCCAGCGCCGCTTTTTTCCCGCCCGGAACACCACTACCGCATCGATCAACTCGTTAGCGAACAGTTCCGACACCATGGCTTGAATCTGGCGGCGGCAGCGGCGGCGGTGGCCGCCCAAGGCGTCCCTCCCCCACATGCGAGTTTTCCATCACCTGCAGAACGGGCACCTTCTGCGTCTAGTGTTCCGTCAAGGGAACGCAGCACGCCCAACCAACCCCTTTCATTAGAACCACAACTGGATTTTTACTCGCAGCGGTTGAGGCAACTCGCTGGTACAACCAGTCCGGGAGCGGCTCAGGCGAGCTCGCCGTCTCCACGGAAGCACTCACCGCCATTCGCCAGTCCCTCGCCATCGCAGCTGCCACCCACGAGTATACCAAACAACATCAGCAGCAGTAGCAGCAGCAGCAATAACAACAACAACAATAACAATAGTAGCAATAGTGGCGGAAGTAGAGCCACGAGTACGTCACCTCCAGCCAAAGATGATAACACACAACTAACAGCAACTCCAAGGTCGGCTTCAACTCCACCAGGAAAACCCGGATCTCCTCGAAATTCAAACTCAGGAGAAGCAGTACATGCGTGCGAGTACTGTGGCAAGAAATTCAGGTACCAGAATAATTTAGACGCCCATCGAAGAACACATACAGGGGAATTACCGTACAAATGCACGGTTTGTGATCATGCATGTGCCCAAAGTTCAAAACTTAAACGCCACATGAAAATACATCGAACACCAGAAGATCGTACCAGCAATGCCGGTTCTGTGGAAACACTTGATGGTGATGAAAGTGAAGAAGATGACGAAGTGGATGAAGAAGAAGAGGAAGAAGACGAGTTGGAGGAGGAAGAAGCTGAAGATTTATCTGTTCCTACACAAATACCTCCAAAAAACGCCAACCAATCGGCTTCACTAGTCGGGGAACTGATGGATAAGTTCGGTTTGAGCAACATCGCGCAATACAGTGAAGCTTACAAGCAAGCGCTTCAAGAATCAAACTCGGCCCTTAAACTCCAACTCGCGAGTAAAGACCGCGATAACAACAACAGCACCAGCTTGACCAACCAACTGAAACTTCGCGACGAGTTCGCCAAAAGCCTCCTTCCCGGTCCTCCCCCTCAGCCATTGCCTCTGTTCCCGCCGTTCAACGATACGTACGAAGCCACCAAACGGCTGAAACTCGACTTGGAACGCAGCGACTGGTGGCTGCCGGGCTTGCCGCGCGAAAACAAGGGCCTCCCCGGCCCCAGTGCCCTCCTCCCTAACCCCCTAATCAAAAAAGATACGAACAGACGGAACGATACTTGTGAGTTCTGTGGCAAAGTGTTTAAGAACTGTTCGAATTTGACGGTGCACCGGCGCTCGCACACGGGCGAAAAGCCGTACAAGTGCGAGCTGTGTTCCTACGCTTGTGCGCAAAGTTCGAAATTGACGCGGCATATGAAAACGCACGGTCGGATCGGGAAGGACGTCTACCGGTGCAGGTTTTGCGAGATGCCGTTTTCGGTGCCGTCGACGCTAGAGAAACACATGCGGAAGTGTGTGGTGAACCAGGGGAAGGGTCACTTGCTGTCGACGATGCCCATGCTGAGCGGAGACGAGGACTCGTCAGCGAGCATCGCCTCCAAGGAGGCAACATGA
Protein Sequence: MTVELLLKMKLFWKYFIADADGAGTDTHQDILTCGVCQKPFALSDIVRFIQHKVASCNKENFGQCFAATDRERDNDDGALPLSTINTRRPSISAPISGKKASGNRVHTPPPASPRLPAPGDLCVDGAASSTPKRRASASPLTSSSMEDGEDIKPDIKQERMDTTEESSQCKKSRTEFADAESNTTHSEPSNYVCSTCKARLHSAWRLIQHVQHSHGIKIYIESSPTSSKNNNHSTSSASSSSSGCSSGGPPPPPSMRHHLLPPPDLHNPFGVGGLLRLPLPPLNHGPVPPAPLFSRPEHHYRIDQLVSEQFRHHGLNLAAAAAAVAAQGVPPPHASFPSPAERAPSASSVPSRERSTPNQPLSLEPQLDFYSQRLRQLAGTTSPGAAQASSPSPRKHSPPFASPSPSQLPPTSIPNNISSSSSSSNNNNNNNNSSNSGGSRATSTSPPAKDDNTQLTATPRSASTPPGKPGSPRNSNSGEAVHACEYCGKKFRYQNNLDAHRRTHTGELPYKCTVCDHACAQSSKLKRHMKIHRTPEDRTSNAGSVETLDGDESEEDDEVDEEEEEEDELEEEEAEDLSVPTQIPPKNANQSASLVGELMDKFGLSNIAQYSEAYKQALQESNSALKLQLASKDRDNNNSTSLTNQLKLRDEFAKSLLPGPPPQPLPLFPPFNDTYEATKRLKLDLERSDWWLPGLPRENKGLPGPSALLPNPLIKKDTNRRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRIGKDVYRCRFCEMPFSVPSTLEKHMRKCVVNQGKGHLLSTMPMLSGDEDSSASIASKEAT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01481208;
90% Identity: iTF_01481208;
80% Identity: -