Basic Information

Insect: Tribolium castaneum
Gene Symbol: -
Assembly: GCA_000002335.3
Location: NC:1742155-1747564[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.016 0.93 9.6 1.5 1 23 565 587 565 587 0.98

2 7 0.00014 0.0082 16.1 4.6 1 23 607 629 607 629 0.98

3 7 0.0015 0.088 12.8 1.7 1 23 632 655 632 655 0.96

4 7 0.00013 0.0076 16.2 6.3 1 23 662 684 662 684 0.97

5 7 4.8e-06 0.00028 20.7 0.7 2 23 691 713 690 713 0.97

6 7 4.2e-06 0.00025 20.8 0.5 2 23 720 742 719 742 0.96

7 7 2.3e-06 0.00014 21.7 0.3 3 23 749 770 747 770 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.016	0.93	9.6	1.5	1	23	565	587	565	587	0.98
2	7	0.00014	0.0082	16.1	4.6	1	23	607	629	607	629	0.98
3	7	0.0015	0.088	12.8	1.7	1	23	632	655	632	655	0.96
4	7	0.00013	0.0076	16.2	6.3	1	23	662	684	662	684	0.97
5	7	4.8e-06	0.00028	20.7	0.7	2	23	691	713	690	713	0.97
6	7	4.2e-06	0.00025	20.8	0.5	2	23	720	742	719	742	0.96
7	7	2.3e-06	0.00014	21.7	0.3	3	23	749	770	747	770	0.95

Sequence Information

Coding Sequence: ATGCAGAAAATGAATAGTGGACATGTATGTTCGGTACCGGGATGTACCAACAAACAGAAGCCCATGTTTCGTTTTCCTAACCCCAAAAGAGGGTTAGACTTATGCTATCGGTGGAGACAGGCAATCAACAACCCCAAATGGGAAAATGTGACAAACGAGCATCTCAACAGAACTGCGCGTGTTTGTTCCAAACATTTCTTAGATTCTGAACTTGATTCCACCACAAGACTATGTTTAATTAACCGTCTTTTGGTTCCATCTGTCAACTTGCCAACAGCAGATCGTTCATTGGAGTTGGAGCAGTCACCTCCATCCGAAGTGGGCCAGAAAAGGGTGACACATGTAATCAAAGGTGCACCTTTATTTTCTTTGGATAGAGAAGTTAAACGAGTTGTATATGCGTGTAAATTTCCGTTGTGTAAAAGTGCCGCTTATCGTAATTATCGCTTTAATAAGAGATTCTTCAAATTTCCCAGAGATCAAGAAAGACAACAGGTTTGGAGAACAATTTGTAACATTGAGCCTCACGTTCGATGCGAAGATTTTCGCGTTTGTGAAGATCATTTTGAAGCATCTGATTTTTTGGGAAGTCGATTGCTTTTGCCCTTTGCTGTTCCTAAAGCTGTTGTCTTGAATGACAACGGGGAACAAGTAAAAATGTCTGTTGGTCCTTCATACAACAGAGAGAATCAAAGAATCCAAATAGACCTACCAATAATACGAGCCGATAAGGTAAATCGTCAAAAATTCAACTTTGAAAATTTAGTTCAAAATGTTAATCCAATAAAAACCTCATTAAAAGAAGCCTTGGGCGTTTTAACCGATCCAAACGTAGAACCTAATATTTTTCACGAAGAAATACAACAATATGAGACTTTTGATAATGAGAGTGAAGAATGTGCTCCATCATGTCCCTCACCACTTCCACCTATGGTTCCGACAAACGTGCCCCCACCTCTTATTATTCCGTCATATAGTTCGATGTATCAAGATATTAATCATGGAATAATCGAAATTGGCTGTCCCACACGCGATAAAGTTGTTGAAATAACAAAACCCTACTTCAAAGCACTGAAAAGTTTTTCTTTAGAAAGTAATTCAGTCCACGAGGTATGTCGGATTTGTTTCCGCTTATTAAAAGAAGAAGAAATTGTCAAACTGTACGATGAGGGGCCTCCTTCCCAAGAGACAAAAGAATTGCGCGATATGTTAGAATTTATTTTGCCCGAATTGGACCTCGAATTATATACAAATGTTGTTGTTTGTACGAAATGTAGAGACCTTTTGGCCTTCAGTTACGAGTTACAACATGCCTGGATGTGTACGGAGAAGAAATTGCAAAAAGTAGTTGAAGAAAAGAAAAGCTTAACAAATTTAAGCTCCGATTTAGTTATTGTAACGGAATCATCTGTTGGCGACGTAATGAGAGAACACCATCAAGATGTAATTAATGTTGATCATGATTACGAAAAGAATGTTGAAAATGCACCAGTTTTGAAAAGAGATGAAGTCCAATATGTGGCGCGCAGAATTCTTGATAATATTCCGGAAGACCCTATAAATGTAAATGAGGATTTTCTAACAAAGAAGAAGCTGAAATTCTTTTACAGAGGAGTTAATTTGAGTTCGTATAATCTGATTGGGTTCAGAACCAAAAGAAAAGAAGTCGGGACCAAATGGGGTGAGGGACCTTATATTTGCGAAATGTGTGCGTTTTTCACCAAAAGTTTGATTTCCTTCCAACGACATTTGCGCAAACATGCGACCAATAAACTGTCTGGTGATATTCCAAAGAAGAAAAAACCAAGGATTAAATCGTTCAAATGCGATAAATGTGATCAGTTGTTTACTAGTCAACAGCATCTCGAACGGCATTTCTTAAAGCATCAGACTTATAAATGCGGAATATGTGAGAAAGAGTTTAAACTGAATAGTATACTACGAAAGCATGTTAAACATGTGCATTTGAAAGATTACAACTATTACCAGTGCCATTTGTGCGGGAAACAATTTTGTTACAAGGATTCTTTGAGGTTGCACTTCGTGACACATAATTCTGTTAAAACAGTAAAGTGTGATTTATGTCCGAAAAAGTTTGCAACGAGGGTTAAATTAACTAAACATCTTCGATCCGTACATAGCGATGCTCCTCCATTAACTTGCAGTTATTGTGGCAAGTCTATAAAGAATGAAAAGAATTTGGAGAAACATATTCAGGTGTATCATTTTCATCAAGGGGATATTTGTGATATTTGCGGGAAACCATTTTCGAAAAAAGATTATTTGATAAAACATAAAATGCGGGTTCATGGTGTTGGAACATTGTGA
Protein Sequence: MQKMNSGHVCSVPGCTNKQKPMFRFPNPKRGLDLCYRWRQAINNPKWENVTNEHLNRTARVCSKHFLDSELDSTTRLCLINRLLVPSVNLPTADRSLELEQSPPSEVGQKRVTHVIKGAPLFSLDREVKRVVYACKFPLCKSAAYRNYRFNKRFFKFPRDQERQQVWRTICNIEPHVRCEDFRVCEDHFEASDFLGSRLLLPFAVPKAVVLNDNGEQVKMSVGPSYNRENQRIQIDLPIIRADKVNRQKFNFENLVQNVNPIKTSLKEALGVLTDPNVEPNIFHEEIQQYETFDNESEECAPSCPSPLPPMVPTNVPPPLIIPSYSSMYQDINHGIIEIGCPTRDKVVEITKPYFKALKSFSLESNSVHEVCRICFRLLKEEEIVKLYDEGPPSQETKELRDMLEFILPELDLELYTNVVVCTKCRDLLAFSYELQHAWMCTEKKLQKVVEEKKSLTNLSSDLVIVTESSVGDVMREHHQDVINVDHDYEKNVENAPVLKRDEVQYVARRILDNIPEDPINVNEDFLTKKKLKFFYRGVNLSSYNLIGFRTKRKEVGTKWGEGPYICEMCAFFTKSLISFQRHLRKHATNKLSGDIPKKKKPRIKSFKCDKCDQLFTSQQHLERHFLKHQTYKCGICEKEFKLNSILRKHVKHVHLKDYNYYQCHLCGKQFCYKDSLRLHFVTHNSVKTVKCDLCPKKFATRVKLTKHLRSVHSDAPPLTCSYCGKSIKNEKNLEKHIQVYHFHQGDICDICGKPFSKKDYLIKHKMRVHGVGTL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01480163;
90% Identity: iTF_01480163;
80% Identity: iTF_01480163;