Tcas008984.1
Basic Information
- Insect
- Tribolium castaneum
- Gene Symbol
- HIVEP3
- Assembly
- GCA_000002335.3
- Location
- NC:2224432-2238260[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 1.4e-05 0.0008 19.2 0.5 1 23 134 156 134 156 0.98 2 8 0.0016 0.097 12.7 5.2 1 21 162 182 162 186 0.89 3 8 0.054 3.2 7.9 0.3 2 20 340 358 339 360 0.92 4 8 2.4e-06 0.00014 21.6 2.1 1 23 876 898 876 898 0.99 5 8 1.2e-06 7.2e-05 22.5 4.7 1 23 904 928 904 928 0.92 6 8 0.00015 0.0087 16.0 2.1 2 23 1332 1353 1331 1353 0.97 7 8 0.00027 0.016 15.2 4.6 1 23 1359 1383 1359 1383 0.92 8 8 0.0012 0.07 13.1 2.2 1 23 1401 1425 1401 1425 0.93
Sequence Information
- Coding Sequence
- ATGGAAAACAGCGCCGCCAGTTATTTGCACAAGAAGTTCAAGAAGCAGCTGAGCATCGATCCGTCGAAACAACACCACCACCAGAATGAGAGCAAGGGAGTCGTGGACACGCGTCAAGAAAAAACCCCCGAACCTAATCAAACTTGCAAAGACAATAACGAAAGTGTGCCAAACCAGAGTACAAATCAAAGCAGTTCTCTCTCAAAGTCTTCCATATCAGTAGAGCAGTGTTGTAGCGTGATTTTACAATCTTCGAACTCGTGCATATCGAAAACCTGGACCGAACCAGTCAGCACGTCTTCTATTTTAGATAACTTATACAAAGTCAAGCCCGAAGATGTAGCTTCGAAGGACCACGAAGAAGCCGAGAAAACCCCCGACAAGTCCTCGGCCGGCAAATATGTGTGCCCCTACTGCAACCTGGTGTGCTCCAAGCCCAGTGTGTTGCAGAAACACATCAGGGCGCACACCAACGAACGCCCGTTCCCGTGCAACAGTTGCGGGTTCAGCTTCAAGACACGCTCGAATCTCTACAAACATTGCCGGTCGAGGACGCACGCTAACCGCGTCATGGGCAACAAGGCGCAAGAGATGGGAGAGGCGGACGAAGGGCCCAAAAGCCCCCAGTGCAGTGACGGCACCATCGAGGACAGAGCGCAAGACCTCAAGACCAAACCCTACAAACCACGCTTCCACACCAAGCACATCTTCAAAGAGAACGAAGAAAACAAAGACGAACCCAAACACAACTCCAACATCCTCTCGGACCACATCAACGAAATCATCAACAAGAACAACTCGATTGTCAACTCGCACGATCCCTACTTGCTGAAGAAGAGGCCAGAGGTGGAGGACCACCACCAGAGACACATCACCGACTTGATTTATTTGAACAACAACGACGAACCCTTAAACCTTACGAAAAACCGCAAGCGGTGCATGAGCGAAGTTGTGGAACCCGGAACTCAGAAGAGTTTGATCAAAGAGTTGCTCCTCAAAAATCTAAATTCGGATATGCAATGCCCACATTGCAAAATGATTTTTCAAACTGTCACTGAGTTGGAGTTGCACAAGCTGAGGAGTTGCAAAGGTTTCGTCAAACCTGGTGCCAAATACAGTCGGAGTAGTTCAGTCAATGTTGCGTCGATTCTTACGCAGAACAAGAACGCCTTTGACAATATACCGCACCTACAGAACGCGGTGTTTCCCCTAAAATCACCGGGTCCCTTCTTGGGCAAGACCCGATTGGTCGAAAGTGACAAAAACAAATCGTTTTCATTCGACGATGGCCTTCCGACAGCTTTCCCACCTTCGACACCCACTGAACGCTATTTACTCTCGCCCTTGACTTTACCGAGCGAACGCGAAAAAAAGACTCCAGTGAAGTTGTTCGGTGGTGAAGTCAAAATCACGCACACGTCCGGCGAAACGAAGAGTTTCAAAATTGATAACAAGGACGATAAGTTTGACAGTGGCTTTGTGGAGTACAGTGGCAAAGTGAGTGAGAATCGGGTGGTGAAGTCCGGGTTACAGTCAGGTGGTACCGTTCTAACCAACAAAGCTAACTACCCCAAGGAGGATTCTTTACGGACAAATCCCGACGTTATTAGGGTGTACGACAACACTCCAGCCTCGCCTAACATCGGAGTCAACCTAACCAAACCCCAAATCACCTACAGGGGAAGTACCGACCCAATAATAGAGTACGCCGTCCCGCCCTATAGCAAATACACAAACATCGTGGATTTTAGCCAAAAAGCCGTAAAACTCCTAACACCGAATTTAAAACAACCCAATCTCGCGGTCCCCGGCGTGCCAACCCCCAACCATTTCACTTTCCCAAGTTTCACTGAAGAGAAAATAATCGATTTGGAAAAACCCGAGCCGCAACAAAAAGTCTTCCAACCCAAAATCATAACTCCACAACCGGTCTGTAACCCCGTCAAACTCCTAGTCAATGGAAAAGTCGTCCGTCATGTCCCTGGGATTCCCGGCCCGGTCGTACCCGAAGACCAACCCCCACCCCGGCTCAAGCCCGAGCCGAAACCGCTCGAAGTGAAAATCGACCATCCGGCCGATAAATCCCCGGTTAAAATAACCGAAACGAAAAAATTCGCAAGGCCTAATAGTCTCGCCTTGAAACCGACAACGGCCTCTTTGAAACAACACCACGGTCTAACACCGACGCTATTTAACCAGATTTTGATCAGTCCTGACACACCTCGTGTGGCGAAGAAATACGTCCATCAGTTTTTGCACGGGAATTATTTCAGTTATTTGGGTTTGAAGTGTTCGACACGGACGGTGTATTGTACGCTGAATAAGACTCAGCCGTTTTATGTGCAACATTTTAAAAAATTGAGCATGTACTCCGAGTGGCGGCAGCAGGACACCAAGACGGAGAAGTTGTACGTGAGTGCGTACGATTCGAGGCAGAGGCATCAGAGGTACACCACGGCGGGGAAGACCACAGCGGATTTGGTGCATTCGAGTTATAAGTTTGTCGTTTCGGAGTCTTCGAGTGGCGGTGATAAGTCCGAAGAGGCGCACAAATCGGCCACAATTCTGGGCGGTTACGAATGCAATGAAGACTACACTTATATCCGAGGCAGAGGCCGAGGGCGTTACGTTTGTGACCAGTGCGGGATCAGGTGCAAAAAACCGTCAATGTTGAAGAAACATATCAGGACGCATTCGAATGACAGGCCGTATACTTGTAATCATTGTAATTTTAGTTTCAAGACAAAGGGGAATTTGACGAAACATATGAAGAGTAAAGCACACACAAAGAATTATGCGGCTAGTGGATCAGGATCGTCGACACAACAGAGTGGTACACAAAGTTCTGAGTCGGATACGGAGGACAGCGGGATGGATAGTAGTGATGAATCAACACGTCGAGAGGAGCATGAAGCGGCCTACGGCCTCCTTTCCCTCTCGCAGAAAACCTCGCAGAGCCTTCGTCGGGAGTCCACAAGTCCAATGTCCACATCGGGCTCCGACCCCCAAGTTTTAAACACGGAAGAAATAGCTCACGCTTCCAAGACCAACTACGCGAAAAACAAATTTCTCGATGATAAAACACCGCTCAATTTCAGCGTCCCTAAAGTCACCACTACCACCATCAGTAGCACCACCACATCATCGGACGAAGAAGTCCAAAACTTGACCCAGTTCCTAGGCAAGACGACAATCAATCGACCACTGACTTACCCCTACACTTCGATTTTACCCCCGGAGTGTACCAGTCAAGAGGTGGCGGAAAATCCGGAAACGAAAAGTATCAAACAGTTCCACGTGATACAAAAGTACGCCTCGAGGGAATCCCCGACTGTGGACAGTAGTGCCAATTGTTTGACTAGTAGTAAAAGTGCAAAGGATAGGACACGAGTGCCAAGTGATCATAAAGTGAACAATGTACCGGTTCTAAAAGTCAACGATGCTGTGGTGCTCGGTGATAGTGTGACTGATTTGAGGAAACGAAAATTGAGTTATGCGGAAAGCGAGTTCGAGAGAGTGAAACAACACAAAACGGACGAAGTGATGGACTTGTCAATGCCAGTCGAGAAAAACCCCGAATTGAGGTACAATGGATCGCCTCAACCGTACCACCATAACCTGATTAAAAAAAACGAAGATCTCTACCCGTCATCGAAGTTCGTCGACGAGAAATTGCCGGTGAAAAACAACGGTTTCGTGAGTGTGAACATCAACTACGTGATACCGGACAGTCAACCGATAAACTGTGAATCCCCCAAAATAGTGTACAAAACGGTCGATTATGATAACAGTGCAATGGAAACGTTGGCTGACATTGCCACCAAACAAGTGAAACTCGAGAAAAATACTCTTGCGAAAAGTGTGGCGACGGAGTTTTTGAAAATTGCAACGAAAAATGAATTTCCATCAGGCGATGCGACGCGAGAAGCGAACACTTTCGGACCGGTGACCAAAGAAGTCAACGATCTGATCGTCAAGCCTGAAGGGAACAAAAGCTGCCACATCTGTGCCAAAAGTTTCAGCAAAACGCCACAGTTGAGGCTGCATATGAACATCCACTACCTGGAGCGTCCGTTTCGTTGCCACTCGTGTTCGGTCAGTTTTCGCACCAAGGGCCACTTGCAGAAGCATGAGCGAAGTGCTAGTCATCACAACAAACTGTCGTCATCGCCTGCTTTGTCCTCGTCGGAGCCTCGGCCGTTTAAATGCGTCGATTGTAATATAGCGTTTCGAATTCACGGCCACCTAGCGAAACATTTGCGCTCGAAAATGCACATCATGAAATTGGAGTGTCTCGCGAAAATACCGTTTGGTTTGTACGCAGAGTTGGAAAGGTCTAACAGTCTGTTGACGGAAATTAACACTGCTGATGGGGACCAATGTTTAGAGAGCTTAAAGACTTTAGCCAAGAAAGTTTTTATCAACGATCCAAATAAATTAAATCAATTGAATTCAGCGGAGAGTATAGATGCCGATAGCTAG
- Protein Sequence
- MENSAASYLHKKFKKQLSIDPSKQHHHQNESKGVVDTRQEKTPEPNQTCKDNNESVPNQSTNQSSSLSKSSISVEQCCSVILQSSNSCISKTWTEPVSTSSILDNLYKVKPEDVASKDHEEAEKTPDKSSAGKYVCPYCNLVCSKPSVLQKHIRAHTNERPFPCNSCGFSFKTRSNLYKHCRSRTHANRVMGNKAQEMGEADEGPKSPQCSDGTIEDRAQDLKTKPYKPRFHTKHIFKENEENKDEPKHNSNILSDHINEIINKNNSIVNSHDPYLLKKRPEVEDHHQRHITDLIYLNNNDEPLNLTKNRKRCMSEVVEPGTQKSLIKELLLKNLNSDMQCPHCKMIFQTVTELELHKLRSCKGFVKPGAKYSRSSSVNVASILTQNKNAFDNIPHLQNAVFPLKSPGPFLGKTRLVESDKNKSFSFDDGLPTAFPPSTPTERYLLSPLTLPSEREKKTPVKLFGGEVKITHTSGETKSFKIDNKDDKFDSGFVEYSGKVSENRVVKSGLQSGGTVLTNKANYPKEDSLRTNPDVIRVYDNTPASPNIGVNLTKPQITYRGSTDPIIEYAVPPYSKYTNIVDFSQKAVKLLTPNLKQPNLAVPGVPTPNHFTFPSFTEEKIIDLEKPEPQQKVFQPKIITPQPVCNPVKLLVNGKVVRHVPGIPGPVVPEDQPPPRLKPEPKPLEVKIDHPADKSPVKITETKKFARPNSLALKPTTASLKQHHGLTPTLFNQILISPDTPRVAKKYVHQFLHGNYFSYLGLKCSTRTVYCTLNKTQPFYVQHFKKLSMYSEWRQQDTKTEKLYVSAYDSRQRHQRYTTAGKTTADLVHSSYKFVVSESSSGGDKSEEAHKSATILGGYECNEDYTYIRGRGRGRYVCDQCGIRCKKPSMLKKHIRTHSNDRPYTCNHCNFSFKTKGNLTKHMKSKAHTKNYAASGSGSSTQQSGTQSSESDTEDSGMDSSDESTRREEHEAAYGLLSLSQKTSQSLRRESTSPMSTSGSDPQVLNTEEIAHASKTNYAKNKFLDDKTPLNFSVPKVTTTTISSTTTSSDEEVQNLTQFLGKTTINRPLTYPYTSILPPECTSQEVAENPETKSIKQFHVIQKYASRESPTVDSSANCLTSSKSAKDRTRVPSDHKVNNVPVLKVNDAVVLGDSVTDLRKRKLSYAESEFERVKQHKTDEVMDLSMPVEKNPELRYNGSPQPYHHNLIKKNEDLYPSSKFVDEKLPVKNNGFVSVNINYVIPDSQPINCESPKIVYKTVDYDNSAMETLADIATKQVKLEKNTLAKSVATEFLKIATKNEFPSGDATREANTFGPVTKEVNDLIVKPEGNKSCHICAKSFSKTPQLRLHMNIHYLERPFRCHSCSVSFRTKGHLQKHERSASHHNKLSSSPALSSSEPRPFKCVDCNIAFRIHGHLAKHLRSKMHIMKLECLAKIPFGLYAELERSNSLLTEINTADGDQCLESLKTLAKKVFINDPNKLNQLNSAESIDADS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01481188;
- 90% Identity
- iTF_01481188;
- 80% Identity
- -