Basic Information

Insect: Tribolium castaneum
Gene Symbol: -
Assembly: GCA_000002335.3
Location: NC:19275925-19277717[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0086 0.5 10.4 1.7 1 23 157 178 157 178 0.96

2 10 0.016 0.93 9.6 0.4 1 23 220 241 220 241 0.90

3 10 2.4e-05 0.0014 18.5 4.3 1 23 247 269 247 269 0.97

4 10 0.00064 0.038 14.0 1.8 1 23 275 297 275 297 0.98

5 10 8.7e-06 0.00051 19.9 3.8 1 23 304 326 304 326 0.97

6 10 0.0013 0.078 13.0 7.5 1 20 339 358 339 360 0.92

7 10 4.1e-05 0.0024 17.7 3.4 1 23 370 393 370 393 0.96

8 10 1.7e-05 0.00097 19.0 0.5 1 23 425 447 425 447 0.98

9 10 3.7e-06 0.00022 21.0 0.1 1 23 453 475 453 475 0.98

10 10 7.5e-05 0.0044 16.9 1.2 1 23 481 503 481 503 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0086	0.5	10.4	1.7	1	23	157	178	157	178	0.96
2	10	0.016	0.93	9.6	0.4	1	23	220	241	220	241	0.90
3	10	2.4e-05	0.0014	18.5	4.3	1	23	247	269	247	269	0.97
4	10	0.00064	0.038	14.0	1.8	1	23	275	297	275	297	0.98
5	10	8.7e-06	0.00051	19.9	3.8	1	23	304	326	304	326	0.97
6	10	0.0013	0.078	13.0	7.5	1	20	339	358	339	360	0.92
7	10	4.1e-05	0.0024	17.7	3.4	1	23	370	393	370	393	0.96
8	10	1.7e-05	0.00097	19.0	0.5	1	23	425	447	425	447	0.98
9	10	3.7e-06	0.00022	21.0	0.1	1	23	453	475	453	475	0.98
10	10	7.5e-05	0.0044	16.9	1.2	1	23	481	503	481	503	0.97

Sequence Information

Coding Sequence: ATGACGCTCACGAAAGGCATTGTCACGGAGGAGAATTTCCAAAAAATTTGCAAATTTTGCTTGGAAGAAAAAAATTTCATTTTGGCCCTCAACTCAATCATTGAATTCAAAGATATAGACCTGTCTCCTATTAGTATTGCCGATATTTTATCACGAGTGACCTCACAGGGCACAAACAATAGTTTTGAGCCCCTAATCATCTGTCACGACTGTCTCAACGAGTTGAAAATCGCCTATCTCTTCATTCTCAAGTATGAAGAAGCCTACAAGTTGCTACACGCCTTTGTTTCAAATTACGTGAAGAAAGAAGAAGGTGAAAGTGATTGTGGAAATGACAATAATAGTGAGACTGAAGTTCATTACGAGACTCGAAACGTTAGTAAAAGACGCGCGAATTTGAAAAAACGCGGCCGAAAGAAAAAAACTGAATCAAATGAAGCCCCAATTCCTGACGCGTCCAAAGTTTTACACTCTTGCCCCATTTGTACGAAAGACTTCACCGCTTTGGAGCTCCGCGACCACGCACATACTCACAAAGGGCTGAAAAAATACCTCAGTATCCCCCCTGACAAAAAAGTAACCCCGACGACGAAATTTTCGACAAGACGCCATCTTGATAACCCCAATGAGACAATTTTTAAACGCCCTGTAAAGCTCCACAAATGCCCTTATTGTAATGAGGAGTTCCCAGTTAACGAATTTCGCGTCCATATCGACATCCACCGCAAACAAAGTGAATACAAATGCGATAAGTGCGAGCGCGTTTTCAAAAGACTAAACCATTTGAACACACATCGGGTCAAACATTTGAAAGAGTATCCTTACAAGTGTGACCAATGCGGTAAAGGCTTTGTGATCAAAACCAACTACGAGTGTCACATCTTAACCCACACCAACAACGAGCTGCCCCACGAGTGTCGCTACTGTCTTAAAAGATTCTCAAATCCGGAGCATTTAAACCGCCACCAAATCATCCACACCGAAAATGTCACATATTCGGTGAAGTACCGCGTTTGTAAGTGCCACCACTGTCTCAAAACGTTCAAAGACAAAGACGAGTTGAAAAGCCACGCTTGCGTCCCGGTCGAGCAAGCGGTAAACACGCGCTTTCCGTGCAAGACGTGTAAAAAGGTTTTCAAGCACTCGAGCGGTCTCTACAATCATAATCGAAACATACATAAACTGAAAGGTGCCAAAACGCTGTGTTCGGTCTGTGGTCACTACGTGTCGAATATTTACAATCATATGATGCGGCATACGGGGGAGAAGCCCTACCAGTGCAACCAGTGCGAGAAGAGGTTCATTGCGAAGCCACAACTGAGGCAACACCTGCTGGTGCATTCGGGGGTCAAGCCCTACGTGTGTAGTGTGTGCGCGAAGGCGTTTAATAATTTGTACAATTTACAAGTGCATGAGAGGATACATAAGGGCGATAGGTGCCACATTTGCCCCGTTTGCAGCAAGGGCTTTCTCGAGAAGTCCTACTTGAAGAAGCACATGAACGTACATTCGAAAGTTTAG
Protein Sequence: MTLTKGIVTEENFQKICKFCLEEKNFILALNSIIEFKDIDLSPISIADILSRVTSQGTNNSFEPLIICHDCLNELKIAYLFILKYEEAYKLLHAFVSNYVKKEEGESDCGNDNNSETEVHYETRNVSKRRANLKKRGRKKKTESNEAPIPDASKVLHSCPICTKDFTALELRDHAHTHKGLKKYLSIPPDKKVTPTTKFSTRRHLDNPNETIFKRPVKLHKCPYCNEEFPVNEFRVHIDIHRKQSEYKCDKCERVFKRLNHLNTHRVKHLKEYPYKCDQCGKGFVIKTNYECHILTHTNNELPHECRYCLKRFSNPEHLNRHQIIHTENVTYSVKYRVCKCHHCLKTFKDKDELKSHACVPVEQAVNTRFPCKTCKKVFKHSSGLYNHNRNIHKLKGAKTLCSVCGHYVSNIYNHMMRHTGEKPYQCNQCEKRFIAKPQLRQHLLVHSGVKPYVCSVCAKAFNNLYNLQVHERIHKGDRCHICPVCSKGFLEKSYLKKHMNVHSKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01481180;
90% Identity: iTF_01481180;
80% Identity: -