Tcas003606.1
Basic Information
- Insect
- Tribolium castaneum
- Gene Symbol
- Zbtb41
- Assembly
- GCA_000002335.3
- Location
- NW:88926-92876[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.021 1.3 9.2 3.0 1 23 202 223 202 223 0.98 2 12 2.8e-05 0.0016 18.3 0.3 1 23 227 249 227 249 0.97 3 12 6.2e-06 0.00036 20.3 4.7 1 23 255 277 255 277 0.97 4 12 2.3e-06 0.00013 21.7 0.7 2 23 284 305 283 305 0.96 5 12 0.00085 0.05 13.6 1.0 3 23 311 332 309 332 0.95 6 12 0.0051 0.3 11.1 5.1 1 23 338 360 338 360 0.98 7 12 0.0028 0.17 11.9 1.2 3 23 374 394 373 394 0.98 8 12 0.00092 0.054 13.5 1.0 1 23 399 421 399 421 0.98 9 12 0.00068 0.04 13.9 1.2 2 23 428 449 428 449 0.94 10 12 3.5e-06 0.00021 21.1 0.2 1 23 455 477 455 477 0.98 11 12 0.0046 0.27 11.3 4.8 1 23 483 505 483 505 0.98 12 12 8.1e-06 0.00047 20.0 2.6 1 23 511 534 511 534 0.97
Sequence Information
- Coding Sequence
- ATGCGTTGCCGAAGAAAATGTGTGAAGTCGTCCAGTTTTACATCTTCAAGTAGCGATTTCAACACTACAAAGTGTTTAACCGAAATggataataaaatagtttcatGCAACGAAGAATATGAATATTCAAGTGATGAAGAAAGTGAAGTTGAAGATGAACCTTTTGTGTTGAGTAGTGATAGTGAAGATGATGCAATTAGGGACATTTATGGGATTCCCAAAGACTTAAACATTGTGTTTGTCGATATTGAAACGGCAAAGAAAGAACTAAATAGCAAAGGATTCGTTTTAAAGCATTTGGAACAAGACGGAGAGGTCGAGAGAATTGTTTGCACTTGTGATGGAGCATCTCAGTGCTTATATCATATCAAAATAGAAGAGCcattaaacattaaagaaGAAGAGCCAGAAATTCCCAAAATAGAAGTTGAAACAACAAGCTTAAAtgaacttaaaactaaaatgaaacttaaacttaaaaatgaaccagaagaaaaaaaatttgaaacaattgccTCCACCTCTAGGATATCTtctccaaaattaaataattcaaatatcAAAGAtagagaacaaaaaaatccgaaaCCAAAGCGAAAACAATACAAGTGTAAGATTTGtgacaaaatattaaacttatCAGGAAAGTATCATCATCTTCGTACCCACAAAAAACCGTTTGTTTGTGAATTCTGTGGTTTGAGATTTTCACTAAAAGGTAGTCTAAAGGCACACCTTCTACAACatacaggagaaaaaccgcaCGTTTGTGAATTCTGTGGTCGCAGTTTTTCACGAAAAGACTATCTAACGGAACACCTACATCGCCATACAGGAAAAAAACCAATTGTGTGTGAACATTGTGGTAAAAGTTTCAGAACTAAGCcagttttaaaaacacatcTACTTGTACACAATATAGGGTACGGTTGTGAATTTTGTTCGAAAGTTTTCCGATATGAGAAATCACTTAATTCACACAAACAAAATATACATTCGGAGGAAAAACCGTTTGTTTGTACACATTGTAACCAAAGATATTGCACCTTATTGGCATTTACAAATCATCTGGAAACTCATGGTATTAAACGTAAAATCCACGAAAGTGGCCCATTGTTATGTCAAATTTGTGATaaagaatttttgacaaaaaacagATTAAAATCACACTTGTTGACACACGGAGACCAAAAGTTTTCCTGTAGCTTTTGCGCTAAGGCATTTAACACTAAAGCTCGACTTATGATGCACAACAGAGTCCATACAGgagaaaaacaaaacgttTGTAAGTCTTGTGGACGAACATTCAACTCTGTGCCGGGACTCCAACATCATATGTATTTCCACACTGGGGAAAAACCGTACGAATGTAAAATGTGCGATAAAGCTTATGTCCtggctgaaaatttaaaatatcatatGATGGTTCATACTGGTGAAAAACCATATTCGTGTCCacattgtgataaaaaatctaGGAGCAAATTTGACATGGAATGCCACATTAGGATTCATACGGGGGAAAAACCGTTCAAATGTGACACCTGTTCGAAAGCGTTCCGGAACCCGAGATATCTCAAAAGTCATAAAAAGAAGGCACATTAA
- Protein Sequence
- MRCRRKCVKSSSFTSSSSDFNTTKCLTEMDNKIVSCNEEYEYSSDEESEVEDEPFVLSSDSEDDAIRDIYGIPKDLNIVFVDIETAKKELNSKGFVLKHLEQDGEVERIVCTCDGASQCLYHIKIEEPLNIKEEEPEIPKIEVETTSLNELKTKMKLKLKNEPEEKKFETIASTSRISSPKLNNSNIKDREQKNPKPKRKQYKCKICDKILNLSGKYHHLRTHKKPFVCEFCGLRFSLKGSLKAHLLQHTGEKPHVCEFCGRSFSRKDYLTEHLHRHTGKKPIVCEHCGKSFRTKPVLKTHLLVHNIGYGCEFCSKVFRYEKSLNSHKQNIHSEEKPFVCTHCNQRYCTLLAFTNHLETHGIKRKIHESGPLLCQICDKEFLTKNRLKSHLLTHGDQKFSCSFCAKAFNTKARLMMHNRVHTGEKQNVCKSCGRTFNSVPGLQHHMYFHTGEKPYECKMCDKAYVLAENLKYHMMVHTGEKPYSCPHCDKKSRSKFDMECHIRIHTGEKPFKCDTCSKAFRNPRYLKSHKKKAH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -