Basic Information

Insect: Tribolium castaneum
Gene Symbol: ECU03_0790
Assembly: GCA_000002335.3
Location: NC:2964336-2969302[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.23 14 5.9 2.7 1 23 73 95 73 95 0.98

2 15 0.013 0.76 9.9 0.3 2 20 101 119 100 120 0.93

3 15 2.7e-05 0.0016 18.3 0.4 1 23 133 155 133 155 0.98

4 15 8.6e-05 0.005 16.7 0.5 3 23 160 181 159 181 0.93

5 15 0.014 0.84 9.8 8.1 1 23 190 212 190 212 0.98

6 15 0.046 2.7 8.2 0.1 1 23 217 239 217 239 0.95

7 15 0.067 3.9 7.6 3.2 1 23 245 267 245 267 0.97

8 15 0.012 0.72 10.0 0.9 1 23 270 293 270 293 0.95

9 15 0.0039 0.23 11.5 5.1 1 23 302 324 302 324 0.98

10 15 0.0022 0.13 12.3 1.9 3 19 333 349 331 355 0.91

11 15 1.9e-05 0.0011 18.8 1.3 3 23 367 388 365 388 0.95

12 15 0.18 11 6.3 3.6 2 23 396 417 395 417 0.94

13 15 5.4e-06 0.00032 20.5 0.4 1 23 424 447 424 447 0.95

14 15 2.9e-08 1.7e-06 27.7 1.9 1 23 453 475 453 475 0.98

15 15 7.9e-05 0.0046 16.8 6.5 1 23 481 504 481 505 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.23	14	5.9	2.7	1	23	73	95	73	95	0.98
2	15	0.013	0.76	9.9	0.3	2	20	101	119	100	120	0.93
3	15	2.7e-05	0.0016	18.3	0.4	1	23	133	155	133	155	0.98
4	15	8.6e-05	0.005	16.7	0.5	3	23	160	181	159	181	0.93
5	15	0.014	0.84	9.8	8.1	1	23	190	212	190	212	0.98
6	15	0.046	2.7	8.2	0.1	1	23	217	239	217	239	0.95
7	15	0.067	3.9	7.6	3.2	1	23	245	267	245	267	0.97
8	15	0.012	0.72	10.0	0.9	1	23	270	293	270	293	0.95
9	15	0.0039	0.23	11.5	5.1	1	23	302	324	302	324	0.98
10	15	0.0022	0.13	12.3	1.9	3	19	333	349	331	355	0.91
11	15	1.9e-05	0.0011	18.8	1.3	3	23	367	388	365	388	0.95
12	15	0.18	11	6.3	3.6	2	23	396	417	395	417	0.94
13	15	5.4e-06	0.00032	20.5	0.4	1	23	424	447	424	447	0.95
14	15	2.9e-08	1.7e-06	27.7	1.9	1	23	453	475	453	475	0.98
15	15	7.9e-05	0.0046	16.8	6.5	1	23	481	504	481	505	0.94

Sequence Information

Coding Sequence: ATGCGCCACGTGCGCCTCCCTGGCCAAAACATCAAAAAACTAACATTTCGTTCCCAGATTGGTGATATTTTGAAGGAATTGAACAAGACAGAGGGGCCACAAAATGACGATTCGAAGCCGAGCTGTTCGTTCGATGTTGCACAAAAACGTCGATACAATATCAGGGCTCGTAAAAAAATGTCATACATTGAGAATCTCTCCGTTAAAAAAACTACCTACAAGTGTAAAGTGTGCAGTTTTACTGAAAGGACGAAAAAAGTGATGTTGAAACATCTGCAGACACACGTCGGGGCCCCCTTGTCTTGTTTCAAGTGCAAAAAAACGTTCAATGGCAGTGTGGCGTACAAGTGGCATTTGGGGCACTACTGCACCCCCGTGTTTTACGACAAGTGGAAATATAAGTGTAGTTTATGCCCTCGAGAATTTGTTTCAAAAAGAACATTAGCCAGTCATTTACAAGGCCACAAAAGAAATAATTGTGCCTACTGTGATAAAGTGTTAACTCGAAGAGTGCACTTAATCCGACACTTGTTAGAAGTTCACTCGATTAAACTAGAAAGAGATACGTACAAGTGTGATCATTGTGAAAAAAGGTATATAAAAAAGTGTTCATTATATTATCACTTGAAACAACACCTTCCAGACAAATATATATGTCTGGAGTGTGGCAAAGTTAGCGAAACAGTTGAAGAAAATGAAGAACACAAAAAACAACACGATTTACAAAAACACTTCAAGTGTGCAAAATGTGGCGATCGCTTCTCCCGACGTCAACAATATTTATTTCATTTAAAAAGACATAATCAATACAAATGCGTGACTTGTGACGAATTTTATGCCTCAAGAACCAAAGTAATCAAGCACAAGCAACAAGGGCATGAAGTTGAAGGGCTAAACCCCCGTTTTATATGCCCTCACTGTCCGGTGGCATTTCACCGAGAAACCCGCTTTCACATCCACATGCGTAAACACTCAGAGGATAATCGCAGTATCAACTGCAAATATTGCAAGAAAACTTTTGTTTCGCCCTACGCCTACTACAAGCATTGTATTACGATAAATCACGAGAAGTTCAGTCCGGAAATTAACGACATAGCGTGCGAAAAGTGTGGCAAACATTTCGCCAAACGCTACGATTTGAGACAACACTTGTATCGAGTGCATAATACGTCGAAACAATTCGTTTCGTGTCAATATTGCAACTACAAAACTGTTCATAAGTGTAATATGGACCGACACGTGGCGTTACATTTTCGTAAAAGCAATCAATACACGTGCGAATATTGTGGGAAAAATTTCGACAGTATCGCCAACTTGAACGACCACATTACCTACAATCACATACAGACTAGGCAGTTCAAGTGCGATAAGTGTGATAAGTCGTTTAAAAGGAATTCCGAATTGGCGCGGCACCAAGACAGCCATTCGGATGAAAGGCCACATGTTTGCACGTTGTGTGGCAAGACGTATAAGAGGCTAAATCATTTAAAAAGGCATGAAAAGCAGGCACATCATATTGTTAAAGAAACCAGAAGGATTAAAAATGTGTCAGAAGAGCAAAAAAAATCCGAATCGAATTGTGAAAATTTGCCCGAATTGAATTATTGGATCGATAGTGAGGACCTATACAGGGTGTATAATGATGTGTCGTTAACTTATGGCATGTGTGAAGGGTTGGAGGGCGCAGACTTGGCGCAAAATGAAAACAACTCGTGTTAA
Protein Sequence: MRHVRLPGQNIKKLTFRSQIGDILKELNKTEGPQNDDSKPSCSFDVAQKRRYNIRARKKMSYIENLSVKKTTYKCKVCSFTERTKKVMLKHLQTHVGAPLSCFKCKKTFNGSVAYKWHLGHYCTPVFYDKWKYKCSLCPREFVSKRTLASHLQGHKRNNCAYCDKVLTRRVHLIRHLLEVHSIKLERDTYKCDHCEKRYIKKCSLYYHLKQHLPDKYICLECGKVSETVEENEEHKKQHDLQKHFKCAKCGDRFSRRQQYLFHLKRHNQYKCVTCDEFYASRTKVIKHKQQGHEVEGLNPRFICPHCPVAFHRETRFHIHMRKHSEDNRSINCKYCKKTFVSPYAYYKHCITINHEKFSPEINDIACEKCGKHFAKRYDLRQHLYRVHNTSKQFVSCQYCNYKTVHKCNMDRHVALHFRKSNQYTCEYCGKNFDSIANLNDHITYNHIQTRQFKCDKCDKSFKRNSELARHQDSHSDERPHVCTLCGKTYKRLNHLKRHEKQAHHIVKETRRIKNVSEEQKKSESNCENLPELNYWIDSEDLYRVYNDVSLTYGMCEGLEGADLAQNENNSC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01481144;
90% Identity: -
80% Identity: -