Basic Information

Insect: Tribolium castaneum
Gene Symbol: -
Assembly: GCA_000002335.3
Location: NC:13796940-13798911[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00023 0.013 15.4 1.0 1 23 78 100 78 100 0.98

2 16 0.0032 0.19 11.8 4.0 2 23 106 127 106 127 0.98

3 16 0.003 0.18 11.9 4.4 1 21 133 153 133 155 0.94

4 16 4.9e-06 0.00029 20.6 1.3 1 23 161 183 161 183 0.98

5 16 0.2 12 6.1 2.9 1 23 189 211 189 211 0.96

6 16 4.6e-05 0.0027 17.6 0.6 2 23 218 239 217 239 0.97

7 16 5.3e-06 0.00031 20.5 0.3 1 23 244 267 244 267 0.98

8 16 0.00034 0.02 14.8 0.5 2 23 271 292 271 292 0.96

9 16 2e-05 0.0012 18.8 0.5 2 23 299 321 298 321 0.95

10 16 8e-07 4.7e-05 23.1 1.2 1 23 328 350 328 350 0.98

11 16 8.2e-05 0.0048 16.8 1.1 1 23 354 376 354 376 0.98

12 16 1.4e-05 0.00082 19.2 2.2 1 23 382 404 382 404 0.98

13 16 0.0041 0.24 11.5 3.2 1 23 410 432 410 432 0.96

14 16 8.9e-05 0.0052 16.7 1.0 1 23 438 460 438 460 0.98

15 16 0.0033 0.2 11.7 6.1 1 19 466 484 466 490 0.92

16 16 0.046 2.7 8.1 4.0 3 23 501 522 499 522 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00023	0.013	15.4	1.0	1	23	78	100	78	100	0.98
2	16	0.0032	0.19	11.8	4.0	2	23	106	127	106	127	0.98
3	16	0.003	0.18	11.9	4.4	1	21	133	153	133	155	0.94
4	16	4.9e-06	0.00029	20.6	1.3	1	23	161	183	161	183	0.98
5	16	0.2	12	6.1	2.9	1	23	189	211	189	211	0.96
6	16	4.6e-05	0.0027	17.6	0.6	2	23	218	239	217	239	0.97
7	16	5.3e-06	0.00031	20.5	0.3	1	23	244	267	244	267	0.98
8	16	0.00034	0.02	14.8	0.5	2	23	271	292	271	292	0.96
9	16	2e-05	0.0012	18.8	0.5	2	23	299	321	298	321	0.95
10	16	8e-07	4.7e-05	23.1	1.2	1	23	328	350	328	350	0.98
11	16	8.2e-05	0.0048	16.8	1.1	1	23	354	376	354	376	0.98
12	16	1.4e-05	0.00082	19.2	2.2	1	23	382	404	382	404	0.98
13	16	0.0041	0.24	11.5	3.2	1	23	410	432	410	432	0.96
14	16	8.9e-05	0.0052	16.7	1.0	1	23	438	460	438	460	0.98
15	16	0.0033	0.2	11.7	6.1	1	19	466	484	466	490	0.92
16	16	0.046	2.7	8.1	4.0	3	23	501	522	499	522	0.94

Sequence Information

Coding Sequence: ATGTTGAGGGGGTGTTTTGAGCCCCCAACGCTCGTAAACGCGCAAATGGGCGAGTTCCAAGACACCCCCAAGACAGAACAACCCCCAGTTTTTGAAAACGTTCAAATTAAGACCGAAACCGAGCACAATTCTAGTCCTGAGGGCGAGTCCGACGAGGATTTCGAGCTGAAGCTCGTTAAAAGTGAAGATTTCGAGCGCAACAACGATGCACTGGATAACGAAACCACACGGTATAAGTGCAACATCTGTTCGCTGGCTTTCAAAGTTTTGGCGGACTATCGAACGCACCGGAAGCAACATTTTGTGGAAAAAAGGACATGTAAGGTGTGCCATACAGTGTGCCAAAGCATCAGTAAACTCGAGATACATATGAACACGCATTTGGGGCTCAAGCCGTACAAGTGCACAGTCTGCGCCAAAAATTTCGTCTCAAGTAATCATCTAAAACTGCACGGGAGGTGCCATTCGGATGAGAAACGATACTCTTGCCAGAAATGCAGCAAGGCGTTTCGGTACTTGGGGTCCCTGAGGAGTCACATGGTCACACACAACGACATCAAGGAGTTTGAGTGTAAGCACTGTGGCGCCAACTCTCGCAACGTTGAAGCGCACCGTAAACACCTCCAATCCCACGGCCAAAAAATCGAAATCAAGTGCGAGCTCTGCAACCGGAACTTTGCAACCGAACGCCTACTGCAAACCCACCTAAACTCGCACTCTGAGTTGCAATACCCTTGCGAATACTGCGGCCGCATCTACCCCTCGTTGTATCGCCTCAAACGCCACATAAAACGCGCACACATTCCCAACGTTTGCGACGAATGCAACGCTGTTTTCTACGATAGAGCTCTATTCACACGCCACAAGAAACAACACAACGAGGGCAAGCCCGTATCGTGTTCAGTTTGTGGCAAAAACTTCGACAAACAGAAGAACTTGAGCGAACATGTGCGCCTCCAACACAAGGAGGACGGTAATGTCCATAAATGTGACTTGTGCGAGAAAATTTTTATCAACGCATCGCTGCTTCGCAACCATATCAAGACGCATGATAAGTGCTTTAAATGCCCGTTTTGCGCTAAATTGTTCAGTTCGAGGTATAATCTCGACACGCATCTAGTGACACACACTGGGGAGAGGAACCACAAGTGCGACATCTGTGGGAATGTGTACTCGACGAAGACCAGCCTTAAGAACCACAAGGCGACTCATAGTGATGCCAGAAATTTCAAGTGTGACCAATGCCCCAAATTATTCAAAACTAATCGGAGATTATACGTTCATAAATTTTCGCATGCCACTGAAGAAAAGTTCGAGTGTGGGGTTTGTAATGCGAGGTTTAAAGTCAAACAGTACTTGAAATATCACATGATCAAGCATTCGAGCAATAAGCCGTTCGAATGCAAAGTCTGTCAAAAAAAATTCAAGCACAAGAAGTCGTGGGAGAAACATTCGAGTCACGACAAACACTTGCGAAACGTTAAAGAGGAGGCGCAAAATTGTGGCGTTTGTGGGCACGTGTGTGTCACTAAAACCGACCTGCTGGAACATAGTAGGCTATGTCATGAGCATGGTATTAAACAAGAGAGTTGTTAG
Protein Sequence: MLRGCFEPPTLVNAQMGEFQDTPKTEQPPVFENVQIKTETEHNSSPEGESDEDFELKLVKSEDFERNNDALDNETTRYKCNICSLAFKVLADYRTHRKQHFVEKRTCKVCHTVCQSISKLEIHMNTHLGLKPYKCTVCAKNFVSSNHLKLHGRCHSDEKRYSCQKCSKAFRYLGSLRSHMVTHNDIKEFECKHCGANSRNVEAHRKHLQSHGQKIEIKCELCNRNFATERLLQTHLNSHSELQYPCEYCGRIYPSLYRLKRHIKRAHIPNVCDECNAVFYDRALFTRHKKQHNEGKPVSCSVCGKNFDKQKNLSEHVRLQHKEDGNVHKCDLCEKIFINASLLRNHIKTHDKCFKCPFCAKLFSSRYNLDTHLVTHTGERNHKCDICGNVYSTKTSLKNHKATHSDARNFKCDQCPKLFKTNRRLYVHKFSHATEEKFECGVCNARFKVKQYLKYHMIKHSSNKPFECKVCQKKFKHKKSWEKHSSHDKHLRNVKEEAQNCGVCGHVCVTKTDLLEHSRLCHEHGIKQESC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01481104;
90% Identity: -
80% Identity: -