Basic Information

Insect: Tribolium castaneum
Gene Symbol: -
Assembly: GCA_000002335.3
Location: NC:9851948-9866712[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 8e-05 0.0047 16.8 1.6 2 23 1281 1302 1280 1302 0.97

2 16 0.0025 0.15 12.1 4.2 1 23 1307 1329 1307 1329 0.97

3 16 0.00056 0.033 14.2 5.2 1 23 1335 1357 1335 1357 0.97

4 16 0.00082 0.048 13.7 0.6 1 19 1363 1381 1363 1384 0.95

5 16 3.6e-05 0.0021 17.9 0.7 1 23 1391 1413 1391 1413 0.96

6 16 0.00057 0.034 14.1 0.1 1 23 1597 1619 1597 1619 0.98

7 16 7.1e-05 0.0042 17.0 7.5 1 23 1625 1647 1625 1647 0.97

8 16 1.7e-07 1e-05 25.2 2.5 1 23 1653 1675 1653 1675 0.98

9 16 0.00013 0.0079 16.1 0.7 1 23 1681 1704 1681 1704 0.93

10 16 0.041 2.4 8.3 2.2 1 23 1718 1740 1718 1740 0.94

11 16 0.00039 0.023 14.7 4.3 1 23 1746 1768 1746 1768 0.98

12 16 3.5e-06 0.00021 21.1 0.5 1 23 1775 1797 1775 1797 0.96

13 16 2.2e-05 0.0013 18.6 1.3 1 23 1803 1825 1803 1825 0.98

14 16 6.6e-07 3.9e-05 23.4 0.9 3 23 1833 1853 1831 1853 0.96

15 16 0.00016 0.0092 15.9 0.2 1 23 1859 1881 1859 1881 0.99

16 16 0.2 12 6.2 0.6 1 23 1886 1909 1886 1909 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	8e-05	0.0047	16.8	1.6	2	23	1281	1302	1280	1302	0.97
2	16	0.0025	0.15	12.1	4.2	1	23	1307	1329	1307	1329	0.97
3	16	0.00056	0.033	14.2	5.2	1	23	1335	1357	1335	1357	0.97
4	16	0.00082	0.048	13.7	0.6	1	19	1363	1381	1363	1384	0.95
5	16	3.6e-05	0.0021	17.9	0.7	1	23	1391	1413	1391	1413	0.96
6	16	0.00057	0.034	14.1	0.1	1	23	1597	1619	1597	1619	0.98
7	16	7.1e-05	0.0042	17.0	7.5	1	23	1625	1647	1625	1647	0.97
8	16	1.7e-07	1e-05	25.2	2.5	1	23	1653	1675	1653	1675	0.98
9	16	0.00013	0.0079	16.1	0.7	1	23	1681	1704	1681	1704	0.93
10	16	0.041	2.4	8.3	2.2	1	23	1718	1740	1718	1740	0.94
11	16	0.00039	0.023	14.7	4.3	1	23	1746	1768	1746	1768	0.98
12	16	3.5e-06	0.00021	21.1	0.5	1	23	1775	1797	1775	1797	0.96
13	16	2.2e-05	0.0013	18.6	1.3	1	23	1803	1825	1803	1825	0.98
14	16	6.6e-07	3.9e-05	23.4	0.9	3	23	1833	1853	1831	1853	0.96
15	16	0.00016	0.0092	15.9	0.2	1	23	1859	1881	1859	1881	0.99
16	16	0.2	12	6.2	0.6	1	23	1886	1909	1886	1909	0.96

Sequence Information

Coding Sequence: ATGTGGACGTTTTTCGCGCTTAATCTCTTCGCGTGGTGTTGTATTGTTGATGCAGTGCCGACACAGAACGACATTGTCAAGAGCTTTGAGACGGCGGTGCAGCAGCAGGACCTTCAATCGATACTGATGTCGATTGAGGAACGATTGAGAAACTTGGACAACATCTACTCAATGCATTTGTCACCAACTCTCGAGGAGAAATTAGAACAATACCAAAGAAAACTCGAAGCAATCGACACGAAAATAATCCGATTGGAGACGTTAGTCATGCTGAATTTAGATAAAATATCGGAAAATATCAGCACGAAGAATTTTAAAGACGATATCGCCAAAACAAACCTACTGAAAAAAGTCGACGCTGTTTATGAGAGTCTCAGTCACAGGATGAGCTACGTTGAGAGAAAATTTGAAAATAGTGTAAATAAAATACAGAGTAAATTAGACACGACGTTAACACGTCTCGAACGAATGGAGGACGGTTTCACTCGCAGGAACGAAGACATCGACTTGGAGCTCTCCGACGCCATCGCCGCCATCGACGACCTAAAAATCAGCTTCAAGGCGGCAGAAGAAGGCATCGTCAACAACACCAACGAAAACTTTGAAATTTCGCTCAAAGAGCACATGTTACTAATGAAAAGCTTCAACGACAAGTCCAACACGGCAATACAAACTTTGTACGAAAACGTGACAAGGGACTTTGACAGGTTAGAACAGAGGATCCAAATGGGATCGCAGGCCATTAACGAAACGGATCGATTTTTAAAAAGCCTCAAGCTCGAACTGAAACGCGAACTTAATGAATACGCCGTTAAAGTAGCCGAAATGAATTCAGAAAACTGGAAAACCGGGGGTATTTTACGAAACAAGCAGGAATCGCTAGAAACCGTAATAAATTCTACAAAAACGGAAGTACAAAACGGGATAAGGACCCTCATGATTCTTATCGGAAAAATTTCGCCGAAAGATAATAGTCCTCAATCAGATCAAGGCCAAATCGAGAAACTCAAAAACGAGATAGATTCCAATTTCAAAAAAGTTTTCTCCGCTCAAGATTTATTCATGGACAATTGTTATCGGCTGCAAATGGACGAGTCTCAAATCGAATCGAAGATCAGCGACATTTTAGAGAAACTGATCGAGACTTTTGATAAAAAAACAACTATCGAAATAAAAGACTTGCAAAATGTGGAGAAACTCATTAAAAACCACGATGCTCACATTTCGCGAAATTTATATCAAGCTGGGACCAATATCGTAACAACTTATGAGAAAATGACCAAAGAGCATCGTCAATTCTCATCGGATTTAAAACAGGTCAGCGACCACCTCAGTGCCCTTTCCGCGCTAATCCGGGACACTCTCGCTGATGAAAACCGTTCTTTATCGTCGAAGAACGTCTCCCTATTACTGAACGAAATGGAAACGAAAATTACGTCTCTCAATAAACAAGGCGATCTCCTCTCGAATTCCACCCGAGAAATAAAGGAGATAGTCGAAAAGCTCCGTCATAAAAATTCCACTGGAGTCATCGATGAATATTTTAGAAATATGTCGGGGATAATTAAAGGGATGGAAGCTAAAGTAAACAGCGCCTATCTTTATTATTACTACAACAGGAGCAAAATTGATGCGATTAATCAGAACCTAAGCCGGCAACTGCAAGAAGTAATTGACGTCATTACGAATAAAACCGAGAGGAATTTAACCGAAACTAAAGACGAAAGAATCAGGAGAATCATCGACGATATTTTCGGAGCGAAACCCGAGGCGAATGAAACACAAGAAACCTCTCCAAATTTGAGTAAAGTAACTGATACGATCGGGGCCAATGAAACACTAGAAATTGCCCCAAATAATTGCACATCAAACGATTTAGACCTCATCGACATGCGGAGCGTATTTGGTTGCGAAAACGCTAAACTTCAAGACATCCCATATATAAATTATCATACAACACCGCCACCTGGAAGTGACGAATACGAAGAGACCGAGAACTATCAACAAGTTTTACGTGGCACTAAGGCCCGGATCTTCCTGTACATATGTGGCGTCTTAATAATAACCGGAATCATTGCGTGTTACAATAACACCTTGTATCAGCTCGAAGATGCAAAGCAGGCAAACGAAATCTGCCACCAGCAGGAAGAGAACTTGTCGACGCAGCTTCAAAGTTTGGCCTTCAAGCATTATAAACAGCGGCTGGAAAAGTCATTAAAGACTGAGAAAGCCGAACATCAAAAAGTTAAAAGTGAGTTAGAGAATAAACTCAATGAAGAGAAAACCAAGAATGAGAAAGGGACGAATGAAGCGAACGTGAGGTTTAATTCGTTGCAACAACACTTCAACTTGTTGCAAACACAATATGAGGACTTGCAAGCGAAGCTGAAGGAGGTTGAACAGGAGTTGAAGGACGTTAAATCTTCAAAGGAGGGTTTAAAGACGAAATATTTGGAAGTGCAAAGCAAAAATGAACGCTTAGAGACTTCTACTCAAGATTTAGAAAAGCAACTGCAAGAAAATGTGAAAGAAAGTACCAATAAAATTAATCATTTGACAAAGGTCAACCACGAGCTGCAGAGGGATTTGACTGACTTGAAGAGCAAATGTCCAACGTACGAGTCTATCCAGCCTCCACAGGTGGCCCCCAACGCCGCCCCCGACTCCTCGCCGAGTTCTCAGAATTTCAGTCGCCAGGTTCAAATCAACGCTAACGAATATCAAATAAAACCTGACGAAAACAATCCAAAGGAAAAGAAGGAAGTAATCCAAAGCCCCCCGAACCAGAACTTTATAAAAACGCCTACAAAATCGACGACTTCGTCGAGTTTGAGAGTCTCTCAGGGGAGTCTGAATGGGGCGAGGCCTCTGCTTATTCCCACTGTGACACCAAAGACCAAAAACGTGCCTCTGCCATACGTGAAGAAACTGCCAGATGGGGTCGTGCCGATTCCCGAAAAGCGTGAAATTGAGAAGAAGACTGAAGATGAAGAGAAGAATGAGTTGCCCGATGAGACTGTAAATAATCGGTACAGAAATAAAATAAGTGATATAGCGATGAAGGAAGATGCGAAGAGGATTGAAGAGGCGGATAAGGAGAATGGGGCCCATGAGGTGTTTGATCAGCATGTGGGAGGGGCGTATGACAATTTTGGGTTCGGGGAGTTGAACGAACATATTAAAAATGCAGAGAAACAGAGTTTTAATAAACAACATATTGACAAATTAGCGATTGAAGGTAACAAAGTTTACGAAAATGAGGAAAATCATCCGATGGAGGAAAACGAACCGGAAGACGATGATCCTGAATATCCCGATCATTTAGGGCGAATGAAAGACGCGAAATACGATGTTTGGAATATAAAATCTCGCAAAAAGTGCCCCAAAACCGCGTTCAGGATGGAGGAAGTCGAATACGACCTTAATCGTATTTGTCGCGCGTGCAAAAACGAGTCCTCGGACATGAGATCGGTGTTTGATGGATGCGAATTGTTGCCCGAATGTCCCCGTATTGACGAGATGCTAATGGCTTGTACCTCGGTGCAGGTGAAAACCGAGGATAAACTCCCCAAATTGATCTGCGCCACTTGCACCGAACAACTTAAAGGGGCCTATATTTTCAAGCAACAATGCCAGGAGACCGACGTCAGTCTCAGGGAGTACGTCAAGAATTTCAAATCGGACGACGATGTCAAGACGGAAGTGGAGGCCACGGGCGGCACTGGCGAAGTTTTGGAGAATTTGGCCGACGAGCTGTCGGAAGACGACCCTTTGAAAGACCTCACCACAAGCCAACGCTCCGACTTCATCGAATTCATAGAAGACAACCAAATGATTCTGACTTGTCGCGAATGTCGCAAAAGCTTCACTCGACTCGAAGGTTTGCGAAGCCACAAGCGTATCCACTTGGGTACGTTATTCAAATGTCGTTTTTGCGGTAAAGGTTACACAAGACAAACTCACGTCTACCGACACGAATTATCTCACGGCAAACACAAACTCCACGTTTGTCGAATATGCAACAAGACTCTGACGAGAATGGAGCACTTGAAACGTCACTTAACGACACATTTAAAGGAAAAACCGTTCTCGTGTAAATCGTGCAATAGAGGATTTAACAGATCGGATCATCTCGAAGTGCACGCTGTGAGGTGCAAGGGAGAGAGGGTACACATTTGTGACATTTGCAATCGAGGATTTTCGCGAGAGGATAGTCTTGAAGTGCACAAGAGGCTGCACGAGAATCAAAAACCAGCACTGCCAACTTTAGAGAACATAGATAATATCGAGGAACATTACTACGAGATTGATTACGATCCTAACATGGATTACTCGGCCGGGTCTGATGTTGATGACTATTTGGAGCCGCATGTGGAAGTTACCGAAAATTTGGATGAGGACAGGATCAAGGAAGTGGAAAGTTTGCAAAACGAGGACAATAGGGAATCGGGGGAGTCGGAAGAGCAAATGGATATTAAAGACATGTTGGAATCTCAGATCGCTCTTGAAATCAACGAAAATGATATCAATATCGACGAAGATAAAAAAATTATTAGCAGGGCGTTGGACAATGACGAGTATGTGCCTGATGACGATGTTGGGCATGACGTTGCAGACAATGACTCCGACAGTGTGGATTCTGAATACCTCCCCACTAAAGTAACGTCTAAAAGACGTCGCGGTCGCGCCCGAAAGAACACCGGTTACAAGAGTACAGGTCGGCCCAGAGGCCGACCTCCAGGTATCAAGCGCGAACGTAAAGACACCGCAAACGACGAGGAAGGCGAATTTCCGTGTCCCAGCTGTAACGAAATCTTCCCTCGTATGAGTCTCTTAGACAAACATGCAAAAACGCACGAAGCCGCCAAAATCCACACTTGCAAAGTCTGCAACAAGGAGTTCTCGAGGTTCAATCATCTGAAACGGCATATGACGTCGCATTCGGTCGTCCGACCCTTCTCGTGCGAGATTTGCGGAAAGCGGTTTTCCCGAAGGGACCACCTGCAGCAACACGTGAGATTGCACGACAAGAAGCAGGAATACAAGTGCGATGTTTGCTTGAAGATGTTCAATAGGGCCGATCAGTTGGCCAAACACAAAGTCTCGAAGCACGAACTGGGCGAAAAGATACAGATGATGGGCGAGAAGAAATTCGAGTGTCACGTGTGTTTAAAAACCTTCACGACTGAAAAATACCGCGACGTGCACGTGAAAGGCCACATGGGCGAGAAGCGTTTCCAATGCAAGACGTGCGAGAAGGCTTTCCTGTCCAAGTCCCACCTAACCGAGCACATGAAATTCCACAACGAACATTCAAAGAAGTTCCTTTGCTCGGAATGTGGCCAGAGGTTCATCAGGAACGATTATCTCGTCATTCACATGAGGCGACATCGGGGCGAGAAACCCTTCAAATGCAAGTTCTGCGGCAAGGGTTTTCCCCGAACCACCGACTTGACAGTGCACGAACGTTACCACACGGGCGAAAAGACCCATCTGTGTACGATATGTGGGCGTGGATTCGGAAGGGCGTACAATTTGACGGTTCATATGAGGACGCATACGGGCGAAAAACCGTACAGGTGCACGTATTGCGAGGCGGCGTTTGCTCAAGGAAACGATCTCAAAGCGCACGTGAGGAGGCATACGGGAGAGCGGTTTCAGTGCGAGTTGTGCACGGAGAGTTTCCTTATGGGGTATTTGCTCACACAACACAAGAGGAGTGTTCACGGTTTGAACGTAGTCAGTAACATAAGACGACTTCACCCCATAAACAAGATAAAACAGGACGCGGACGAGCCGCCTCCGATCACAATTCCATTGCCTAAACCGGTAGTACCTGAAATCCTGATTACCAATATCCAAGCCCACTTGACTCAAATCCAGCATCATCAGATCGCTAGAGAATAA
Protein Sequence: MWTFFALNLFAWCCIVDAVPTQNDIVKSFETAVQQQDLQSILMSIEERLRNLDNIYSMHLSPTLEEKLEQYQRKLEAIDTKIIRLETLVMLNLDKISENISTKNFKDDIAKTNLLKKVDAVYESLSHRMSYVERKFENSVNKIQSKLDTTLTRLERMEDGFTRRNEDIDLELSDAIAAIDDLKISFKAAEEGIVNNTNENFEISLKEHMLLMKSFNDKSNTAIQTLYENVTRDFDRLEQRIQMGSQAINETDRFLKSLKLELKRELNEYAVKVAEMNSENWKTGGILRNKQESLETVINSTKTEVQNGIRTLMILIGKISPKDNSPQSDQGQIEKLKNEIDSNFKKVFSAQDLFMDNCYRLQMDESQIESKISDILEKLIETFDKKTTIEIKDLQNVEKLIKNHDAHISRNLYQAGTNIVTTYEKMTKEHRQFSSDLKQVSDHLSALSALIRDTLADENRSLSSKNVSLLLNEMETKITSLNKQGDLLSNSTREIKEIVEKLRHKNSTGVIDEYFRNMSGIIKGMEAKVNSAYLYYYYNRSKIDAINQNLSRQLQEVIDVITNKTERNLTETKDERIRRIIDDIFGAKPEANETQETSPNLSKVTDTIGANETLEIAPNNCTSNDLDLIDMRSVFGCENAKLQDIPYINYHTTPPPGSDEYEETENYQQVLRGTKARIFLYICGVLIITGIIACYNNTLYQLEDAKQANEICHQQEENLSTQLQSLAFKHYKQRLEKSLKTEKAEHQKVKSELENKLNEEKTKNEKGTNEANVRFNSLQQHFNLLQTQYEDLQAKLKEVEQELKDVKSSKEGLKTKYLEVQSKNERLETSTQDLEKQLQENVKESTNKINHLTKVNHELQRDLTDLKSKCPTYESIQPPQVAPNAAPDSSPSSQNFSRQVQINANEYQIKPDENNPKEKKEVIQSPPNQNFIKTPTKSTTSSSLRVSQGSLNGARPLLIPTVTPKTKNVPLPYVKKLPDGVVPIPEKREIEKKTEDEEKNELPDETVNNRYRNKISDIAMKEDAKRIEEADKENGAHEVFDQHVGGAYDNFGFGELNEHIKNAEKQSFNKQHIDKLAIEGNKVYENEENHPMEENEPEDDDPEYPDHLGRMKDAKYDVWNIKSRKKCPKTAFRMEEVEYDLNRICRACKNESSDMRSVFDGCELLPECPRIDEMLMACTSVQVKTEDKLPKLICATCTEQLKGAYIFKQQCQETDVSLREYVKNFKSDDDVKTEVEATGGTGEVLENLADELSEDDPLKDLTTSQRSDFIEFIEDNQMILTCRECRKSFTRLEGLRSHKRIHLGTLFKCRFCGKGYTRQTHVYRHELSHGKHKLHVCRICNKTLTRMEHLKRHLTTHLKEKPFSCKSCNRGFNRSDHLEVHAVRCKGERVHICDICNRGFSREDSLEVHKRLHENQKPALPTLENIDNIEEHYYEIDYDPNMDYSAGSDVDDYLEPHVEVTENLDEDRIKEVESLQNEDNRESGESEEQMDIKDMLESQIALEINENDINIDEDKKIISRALDNDEYVPDDDVGHDVADNDSDSVDSEYLPTKVTSKRRRGRARKNTGYKSTGRPRGRPPGIKRERKDTANDEEGEFPCPSCNEIFPRMSLLDKHAKTHEAAKIHTCKVCNKEFSRFNHLKRHMTSHSVVRPFSCEICGKRFSRRDHLQQHVRLHDKKQEYKCDVCLKMFNRADQLAKHKVSKHELGEKIQMMGEKKFECHVCLKTFTTEKYRDVHVKGHMGEKRFQCKTCEKAFLSKSHLTEHMKFHNEHSKKFLCSECGQRFIRNDYLVIHMRRHRGEKPFKCKFCGKGFPRTTDLTVHERYHTGEKTHLCTICGRGFGRAYNLTVHMRTHTGEKPYRCTYCEAAFAQGNDLKAHVRRHTGERFQCELCTESFLMGYLLTQHKRSVHGLNVVSNIRRLHPINKIKQDADEPPPITIPLPKPVVPEILITNIQAHLTQIQHHQIARE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -