Basic Information

Insect: Tribolium castaneum
Gene Symbol: ZNF536
Assembly: GCA_000002335.3
Location: NC:10350280-10352111[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 5.6e-08 3.3e-06 26.8 0.8 1 23 206 228 206 228 0.99

2 12 5.9e-07 3.5e-05 23.5 7.4 1 23 234 256 234 256 0.98

3 12 1.6e-06 9.7e-05 22.1 0.5 1 23 262 284 262 284 0.99

4 12 0.00014 0.0081 16.1 1.6 1 23 290 312 290 312 0.96

5 12 0.00012 0.0071 16.3 1.4 1 23 318 340 318 340 0.97

6 12 3.7e-08 2.2e-06 27.3 3.2 2 23 347 368 346 368 0.97

7 12 2e-07 1.2e-05 25.0 2.0 1 23 373 395 373 395 0.98

8 12 4.3e-06 0.00025 20.8 2.3 1 23 401 423 401 423 0.99

9 12 2e-05 0.0012 18.7 1.3 1 23 428 450 428 450 0.96

10 12 3.1e-06 0.00018 21.3 1.4 1 23 456 478 456 478 0.98

11 12 3.2e-09 1.9e-07 30.6 0.8 1 23 484 506 484 506 0.98

12 12 8e-08 4.7e-06 26.3 1.3 1 23 512 534 512 534 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	5.6e-08	3.3e-06	26.8	0.8	1	23	206	228	206	228	0.99
2	12	5.9e-07	3.5e-05	23.5	7.4	1	23	234	256	234	256	0.98
3	12	1.6e-06	9.7e-05	22.1	0.5	1	23	262	284	262	284	0.99
4	12	0.00014	0.0081	16.1	1.6	1	23	290	312	290	312	0.96
5	12	0.00012	0.0071	16.3	1.4	1	23	318	340	318	340	0.97
6	12	3.7e-08	2.2e-06	27.3	3.2	2	23	347	368	346	368	0.97
7	12	2e-07	1.2e-05	25.0	2.0	1	23	373	395	373	395	0.98
8	12	4.3e-06	0.00025	20.8	2.3	1	23	401	423	401	423	0.99
9	12	2e-05	0.0012	18.7	1.3	1	23	428	450	428	450	0.96
10	12	3.1e-06	0.00018	21.3	1.4	1	23	456	478	456	478	0.98
11	12	3.2e-09	1.9e-07	30.6	0.8	1	23	484	506	484	506	0.98
12	12	8e-08	4.7e-06	26.3	1.3	1	23	512	534	512	534	0.99

Sequence Information

Coding Sequence: ATGAACAGTGTGTTCCAGCTAACGGACTGCTGTCGCACTTGTTTGCGCGTTGAAAGTGCTTTAACCCCGTTGGATTCGGTCGACTCCGACAATATAAAATTATGTGATAAACTTGTTGCTTGCATTTCGGATATTGCTTGGACGAAAAATGGATACTCCAACTTGTTGTGTTCGAATTGTATCGAAAAACTCCGGAGTGCGTACGAGTTCCGATTATTGTGTATCCAATCGGAGAACACTTATCAGCAGTATTTTTCCCAGGAAAAAGTCGCCTCTTACACAAATTTGGACGACTTTCAGCTGACTAACACAATTCAAATCCAAGGTGCTGTCATCGAAACTGTTAAAACCAATGATTTCCTAAACCTGAAGCATTTCCTTGACGATGACACAGGAAATAAGCCGCCGGAGAATTCGCGAAGTGCGTCCCCAGATTCAGTTGCCACTACTGGTTTTGCAAAATATGAAAAAATCGTGAAAAAAGCGGTGGTGCCAACCCGGTCTGTGAAAACCCAAACGCAGCCTTTGCCCCAATATCCAAGTCTGACTCCGGCGGCAGCACGGCTGGAGGCCCAACAAAGCAAAACCACGATTATCATAGAAGACCCCTACAAGTTCACGTGCGAGCTTTGCGGGAAAAAATACGCCAAAAACGCCAATCTCAAAATTCACATGAGGACTCACACCGGGGAAAAACCGTTCGAGTGCAAATACTGCGACAAGAAGTTCTATCACTCGTCGCATTTGCGGGAACACATCAGGCGACACACGGGGGAAAAACCGTTCCAGTGCAACGTGTGTCAAAAACGCTTCACGATCACTGCAGAGCTGACAGTCCACATGCGAATCCACACCGGGGAAAAACCGTACGCGTGTAATTGCTGCGAAAAGCGCTACATCAAAGCCAGCGATCTGCAGGTGCACATGCGGTCGCACACCGGGGAAAAACCCTTCGCATGTAATTATTGCGATAAAAAATTCACTTCGGGTTATATACTGAATTCGCACCTGAAAACGCATACCGGAGACCGGCCCTGGCAGTGCAACATTTGCTCAAAGTCGTTCACTCAATCGTCGCATTTAACAGTCCATATGAAGAAACACACTGGGGAGAAGTTCGTTTGTAAAGTGTGCAATGAAGAGTTCACCCATTCGTCCCAATTGACGGTGCATATGAGGCAACACACAGGCCGCCAACCTTACAAATGCACAATGTGCGATAAAATTTGCAATTACGCGTCTGAGTTGCAAACGCACATTATGAAACACACTGGGGAAAAATTCACGTGCATAACGTGCGATAAAAAATTCACAACGGCGGCGTATTTGCAGGAACATACGCGGACGCACACTGGCGAAAATTTGTTCAATTGTACGTTGTGTGAACGCGTTTTTACGAGAGCAACCTATCTTGATAAACATTTAAGGACGCATACTGGCGAAAGGCCTTTCGAGTGTGAAATTTGCGGGAAAAAATTCACACAGAGTAGTAGTCTCAATGTACATATCAGGAAACATACAGGGGAAAAACCCTACACTTGTAATATCTGTAATAGGAGTTTTGCAACGTCGTCTTACCTATCCGTTCATTTAAGGAAGCATAAAAAATATATTAACATGTAA
Protein Sequence: MNSVFQLTDCCRTCLRVESALTPLDSVDSDNIKLCDKLVACISDIAWTKNGYSNLLCSNCIEKLRSAYEFRLLCIQSENTYQQYFSQEKVASYTNLDDFQLTNTIQIQGAVIETVKTNDFLNLKHFLDDDTGNKPPENSRSASPDSVATTGFAKYEKIVKKAVVPTRSVKTQTQPLPQYPSLTPAAARLEAQQSKTTIIIEDPYKFTCELCGKKYAKNANLKIHMRTHTGEKPFECKYCDKKFYHSSHLREHIRRHTGEKPFQCNVCQKRFTITAELTVHMRIHTGEKPYACNCCEKRYIKASDLQVHMRSHTGEKPFACNYCDKKFTSGYILNSHLKTHTGDRPWQCNICSKSFTQSSHLTVHMKKHTGEKFVCKVCNEEFTHSSQLTVHMRQHTGRQPYKCTMCDKICNYASELQTHIMKHTGEKFTCITCDKKFTTAAYLQEHTRTHTGENLFNCTLCERVFTRATYLDKHLRTHTGERPFECEICGKKFTQSSSLNVHIRKHTGEKPYTCNICNRSFATSSYLSVHLRKHKKYINM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00639723;
90% Identity: iTF_01481085;
80% Identity: -