Basic Information

Insect: Triatoma rubrofasciata
Gene Symbol: lola
Assembly: None
Location: chr10:25503634-25517160[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.011 0.66 10.1 0.1 2 22 247 267 246 267 0.93

2 5 0.00054 0.033 14.2 0.6 2 20 279 297 278 299 0.94

3 5 0.0033 0.2 11.7 0.8 2 21 308 327 307 328 0.94

4 5 1.5e-05 0.00093 19.0 1.5 2 22 337 357 336 357 0.95

5 5 0.077 4.7 7.4 0.1 6 21 446 461 446 462 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.011	0.66	10.1	0.1	2	22	247	267	246	267	0.93
2	5	0.00054	0.033	14.2	0.6	2	20	279	297	278	299	0.94
3	5	0.0033	0.2	11.7	0.8	2	21	308	327	307	328	0.94
4	5	1.5e-05	0.00093	19.0	1.5	2	22	337	357	336	357	0.95
5	5	0.077	4.7	7.4	0.1	6	21	446	461	446	462	0.94

Sequence Information

Coding Sequence: ATGGAAGAAGATGATTATTATTTGAAATGGGAGAAGCACCACAGTGCTTTTGTTTCTATGTTTGATTATCTCTATAAACATGACATATTAGTTGATTGCACTCTTGCAGCTGAAGAGAAATGTATTAAAGCACATAGGATTGTTCTAATGGCCTGCAGCTCCTATTTACAAAAAATTTTTCGTGATCATTCAGAAAATTATCCGATTGTCTTTTTTGATATAAAGTATTCTGTTTTGGAAGCAATTGTAAACTTTTGTTACCGTGGTGAAGTGAAAATTTCGGTTGATCAACTTGAAGGATTTATTGAAGCGGCTACAATGTTGCAGATTAAGGGTTTATGTGAAAGTGGTGATAGTGATGTAGTGAGTGATAACAGTGAAACAAATAAGAGACGCTTGTCGTTAACAGACTCTAGTAAAAGTCCTTGTAAAAAAACGAGAACAGTATCAAATAGTAATGAAAGTGACAATGTTATAATTTGTGACGACGATTTGGCTGTAGAACCGGAAGGTGGAGGTGCAGTTAGAGCTGATAGAAATGGATTTCCACATCCCTTAGCTATGGTGAGCGTAAAGCCCGATCGAGAGGACTTGCTTAACCTGGCGAGGGATATGCAAGGTTCAGATAACTCAGATGTGGATTCTGATGATACCGGTGGTAGTAGCGGACCAGAGGGGGAGGATATTAGCCATATTAATGACTTTCTTAAATCAAGCAGTACATTACTCTTTCCTTGGACATGTAACAGATGTGGTGAAGCATTTGCGACTAGGATGCCATACGAGGAACATAGAAGAAAGTGTGTTAAAATTGATCCAGCAAATCATCCTTGGAAATGCCATAAATGTCCTAATGCTTATAAAAATAAAAAGGATCTCGTCCGACATTTAATATATTGTGGCAATGATTTGCCACGGCTCTATTGTAATCGTTGTGGCAACAGTTACAAATACGAACGTGGACTTAGACGACATCAGAAATATTGTGGCACAGATGTAAAACCATTGAAGTGCCCCCAATGCGAAAAAACATATAAATACAAACGTGGTTTACGCAGACATCAACGAAGATGTGGTATTGCTGAAGCATTGCAATTTTTGGCTGGCAAAGGTGTAACACCTGTTGTAGTAACCAAAAGGTCCTTTCATGTGCCAGGCATAGGTGACCTTGCCAAAGCTGCTTTGCCATTAATCAGTGCAACCTCTCAGTTGTCCCAATTAACACAATTATCCACTTTAGAAAAGTCATTAAATTCAACCGAAAATTCTGAAACTAAAGGACAAACTCTTGACATGTTAGGTAATCCATTACTTCCAGATGCCTCAATTTGCCCTTGTGGTAAAGTGTACAAATATAAGAAATCATACGACAAACATATTGCTACTTGTGCATGTGGCAGTATGCAGGACAACACAGCTAATAGAAACCAGCAACAAGAAAACAATGATAATGCTTTCAGTAGTGCTGAACAACTATCAGAATCTGAAGGTGATAATGGGGAAGAAGATGATGTAGAAGATGCTGAGGTAGAAGAAGCTGACGTAGAAGTAGCTGAAGATGACGATAATAAGAGTGAGGAGAGGAATCGAGAAGACTTGGATGAAGAAGATAGTGATATTACAGATTGTGAGGATCAAGCAGTGGATGAAGGCAATAAAGGAAATAAAGAAATTGAAGAAAATATTAATGAAAATCAAGAAATGAGGGAAGAGAATCATGTGAATGAAGAACATTGTGAAGAAGATCATGCAAATAAACATATAGATGAGTCAAAAGGAGATGAACAAATTCCTGAAGTATATAATGTTACTTTGGAAAACTTTGTAGAAGAAGATCAAGAAGTAAGGAGTGAGAAAGAAGGCAATCAGATTGATAGTAATGAAGGTCAAGCAGATGAAAAGAGTGATAACCCAAATGAAGATAATGACAAACCAAAAAAAGAATTGCCAAAGAATGCAGAGGGATGA
Protein Sequence: MEEDDYYLKWEKHHSAFVSMFDYLYKHDILVDCTLAAEEKCIKAHRIVLMACSSYLQKIFRDHSENYPIVFFDIKYSVLEAIVNFCYRGEVKISVDQLEGFIEAATMLQIKGLCESGDSDVVSDNSETNKRRLSLTDSSKSPCKKTRTVSNSNESDNVIICDDDLAVEPEGGGAVRADRNGFPHPLAMVSVKPDREDLLNLARDMQGSDNSDVDSDDTGGSSGPEGEDISHINDFLKSSSTLLFPWTCNRCGEAFATRMPYEEHRRKCVKIDPANHPWKCHKCPNAYKNKKDLVRHLIYCGNDLPRLYCNRCGNSYKYERGLRRHQKYCGTDVKPLKCPQCEKTYKYKRGLRRHQRRCGIAEALQFLAGKGVTPVVVTKRSFHVPGIGDLAKAALPLISATSQLSQLTQLSTLEKSLNSTENSETKGQTLDMLGNPLLPDASICPCGKVYKYKKSYDKHIATCACGSMQDNTANRNQQQENNDNAFSSAEQLSESEGDNGEEDDVEDAEVEEADVEVAEDDDNKSEERNREDLDEEDSDITDCEDQAVDEGNKGNKEIEENINENQEMREENHVNEEHCEEDHANKHIDESKGDEQIPEVYNVTLENFVEEDQEVRSEKEGNQIDSNEGQADEKSDNPNEDNDKPKKELPKNAEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01479540;
90% Identity: iTF_01479540;
80% Identity: iTF_01479540;