Basic Information

Insect: Triatoma rubrofasciata
Gene Symbol: lola
Assembly: None
Location: chr10:25569964-25602441[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00025 0.015 15.2 1.4 1 21 243 263 243 264 0.96

2 8 0.008 0.49 10.5 2.2 1 17 272 288 272 289 0.93

3 8 0.00035 0.022 14.8 0.3 1 19 325 343 325 345 0.95

4 8 0.31 19 5.5 0.2 1 18 355 372 355 375 0.80

5 8 7e-06 0.00043 20.1 0.9 2 21 385 404 384 405 0.93

6 8 0.00012 0.0072 16.3 0.1 2 23 416 438 415 438 0.96

7 8 0.048 2.9 8.0 2.2 1 21 500 520 500 521 0.94

8 8 0.014 0.84 9.7 2.1 1 23 530 553 530 553 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00025	0.015	15.2	1.4	1	21	243	263	243	264	0.96
2	8	0.008	0.49	10.5	2.2	1	17	272	288	272	289	0.93
3	8	0.00035	0.022	14.8	0.3	1	19	325	343	325	345	0.95
4	8	0.31	19	5.5	0.2	1	18	355	372	355	375	0.80
5	8	7e-06	0.00043	20.1	0.9	2	21	385	404	384	405	0.93
6	8	0.00012	0.0072	16.3	0.1	2	23	416	438	415	438	0.96
7	8	0.048	2.9	8.0	2.2	1	21	500	520	500	521	0.94
8	8	0.014	0.84	9.7	2.1	1	23	530	553	530	553	0.95

Sequence Information

Coding Sequence: ATGTCGACAGATCAACATTTTTGTTTAAAGTGGAATAACCATCAAGATACATTAATTTCTTTATTTTCTTCTTTGTTGGACTCAAATACTTTTGTTGACTGCACGCTGGCTGCTGGTGGAAAACAGATAAAAGCTCACAAGATGATACTTTCAGCATGTAGTCCTTATTTTAAGGATATTTTGTTGGAATATGGAGACACACATCCCATCATTATTTTGAACAATGTTCAGTTTTCCGAGCTTGTAGCAATAGTTGAATTTATGTACAGAGGAGAGGTGAATGTAGCTCAAGAGCAACTACCTTTATTCCTTAAAGCAGCTACAGCTTTGCAAGTAAAAGGCCTAACGGACAATAAATCTGATGGTGGTACAAGCGAAGATGGTGGCCGAGATGATGATGACGATGATGAGGAAGGATATACCAGCGAAGTTTCGTCCACAGGTGCAACACCTCGTGGAGGAATTGTAAATGATAGGGCTGATCCGAATAGTTTGAAGATAGATTCTTCCTTGGGTCTACAAGATATTACCACAGGGACATCAGCTGATGATTCTCAAGGACCAGGTCCTTCTAATGGATTACTACAGCAACAGAATTTCTACAAGTTCGGTGAAGATAACCTTTCAACATTAAGTGGCTTACCAGTTGGTAATAGTGCTCTGGCTGCAGCATATGGGAAAATGATCCAGCTAAGACGCCCCAATGCAACTGAGAAAGACGCTTCATTTAGGTGCGAAGTTTGTTCAAAATTCTATCGAAGCAAGACCAGTCTGAATCTGCACAAACGATGGGAATGTGGAAAAGAGCCAAAGTTTGCCTGCCCTTATTGTGATAAGAGGTGCCATCAAAAGGGTAACCTTAAAAATTCTGATAAGATGGTATCTCATATACTCTCCATTCACATGTCTCATATGAAAGCATCCCAGACCAAGTATACTTGGAGTGGTGGTCGAAGATGTCTACCGCCATTATTCTCTTGTGGGGGATGTGGTAAATCTTATCGATGGAAAAGTACATTGCGAAGGCATGAAGAATTTGAATGTGGTGGTAAGCGTCCGTCACACCCATGCCCTTACTGTGATTACGCGGCCAAACAAAAAGTTAATGAACGAGTCCACCGAGACCATAGTTATGTACAAGAAGTTGCAGTAAGATGTGATACTTGTGGAAAGTCCTATCGTCGCAAAAGAACATTAAAACGACATGTATTGAAAGAGTGTGGCAGTATGAAAGAAGAGCTACTACAATGCCCAGTTTGTCCTTATCGTTCCATAAATCCAGACACACTGTCCAGGCATCTAAAAGTGAAACACAGTGTATTGAGAAAAAACACCAACTTTACTTTTCGAGTGGCATTACGTGGTGGAGCAACAATCACTCCTTTGGGCAATTCTAGAAATACTGACTGGTATGCGACCGAAGTGAAAAAAAAGCAAGCAGCAAGGCGTGTAATTAGAAAACGTATGGAGAAACATCGCAACACCACAAGCGGACTGTACGAATGTGATTGTTGCAACCAGACATATTCACGATTTATATCACTGTACAGACATATGGAATACGAGTGTACAGTGACCACTTCAAACCATGCTTGTCCTTACTGCCCATACACCAGTTTCTTCAAACGTAAATTTATTGCACATATGGCCAAAAAACATTACAAACATCTCAACGAAGATTCATAA
Protein Sequence: MSTDQHFCLKWNNHQDTLISLFSSLLDSNTFVDCTLAAGGKQIKAHKMILSACSPYFKDILLEYGDTHPIIILNNVQFSELVAIVEFMYRGEVNVAQEQLPLFLKAATALQVKGLTDNKSDGGTSEDGGRDDDDDDEEGYTSEVSSTGATPRGGIVNDRADPNSLKIDSSLGLQDITTGTSADDSQGPGPSNGLLQQQNFYKFGEDNLSTLSGLPVGNSALAAAYGKMIQLRRPNATEKDASFRCEVCSKFYRSKTSLNLHKRWECGKEPKFACPYCDKRCHQKGNLKNSDKMVSHILSIHMSHMKASQTKYTWSGGRRCLPPLFSCGGCGKSYRWKSTLRRHEEFECGGKRPSHPCPYCDYAAKQKVNERVHRDHSYVQEVAVRCDTCGKSYRRKRTLKRHVLKECGSMKEELLQCPVCPYRSINPDTLSRHLKVKHSVLRKNTNFTFRVALRGGATITPLGNSRNTDWYATEVKKKQAARRVIRKRMEKHRNTTSGLYECDCCNQTYSRFISLYRHMEYECTVTTSNHACPYCPYTSFFKRKFIAHMAKKHYKHLNEDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01479532;
90% Identity: iTF_01479532;
80% Identity: iTF_01479532;