Trub011283.1
Basic Information
- Insect
- Triatoma rubrofasciata
- Gene Symbol
- lola
- Assembly
- None
- Location
- chr10:25261753-25297992[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 1.5e-05 0.00089 19.1 0.9 1 21 11 31 11 32 0.95 2 16 0.89 54 4.1 1.5 1 16 40 55 40 57 0.87 3 16 0.0059 0.36 10.9 1.0 1 20 106 125 106 127 0.95 4 16 1.4e-05 0.00085 19.2 1.6 1 23 135 158 135 158 0.96 5 16 0.17 10 6.3 2.6 1 21 177 197 177 198 0.93 6 16 0.0012 0.072 13.1 0.4 1 23 206 229 206 229 0.93 7 16 0.063 3.8 7.7 0.7 6 21 266 281 264 282 0.93 8 16 0.0005 0.03 14.3 2.1 1 23 290 313 290 313 0.94 9 16 0.00045 0.027 14.4 1.9 1 21 538 558 538 559 0.93 10 16 3.2 2e+02 2.3 0.4 1 13 567 579 567 582 0.82 11 16 0.029 1.8 8.7 5.4 5 20 591 606 587 608 0.89 12 16 0.00016 0.0095 15.9 1.9 1 23 616 639 616 639 0.96 13 16 0.00055 0.033 14.1 2.5 1 21 648 668 648 669 0.95 14 16 0.0011 0.07 13.1 3.2 1 21 683 703 683 704 0.95 15 16 2.9e-05 0.0018 18.2 3.7 1 21 714 734 714 735 0.96 16 16 0.00086 0.052 13.5 0.6 1 23 743 766 743 766 0.93
Sequence Information
- Coding Sequence
- ATGAGCATAGGAAAAGTTGTAATGGCCAGACATCGTTGTCCAACTTGCGGCAAATCATTCAAGTATAAAGCCGGATTATATCAGCATAGAAAACATGATTGCGGCAAGGACTATCATTTTTATTGTCCATATTGTGCTTACAGATGTCGTCGAAGTGAATTTTTAGCTCTTGAAGGTGATTGGCGTGAAAAGGAGTATCCGGGAGTCATCGGCACCACGAGCAATGTTAATCGAAAACGTAAAACAGTCCAAAATAATGCTATTAGTGGAAGTCTTCTAACCAATGTTCCTGTAACCAAAGATGGGCCAGTTAAATATACATGTACAGCATGTGGCAAAGTGTATCAACATCGACAGAGTTTATATAATCATGTATCATATCAATGTGGACGTGAACCACAGTTTGCCTGTCCATATTGTCAGTACAGATCTAGACATAAAGTTAATTTAAAACGCCATATTGCTACGATTCATATGGTAGGTTTACGTGAACAGTTAGGAAGCAATTCAGTATTATCAAATGAAAAATTCGCTTGCAATCAATGCTTCAGATCATATGTGCATATACAAAGTCTATACAAACATAAGAAATTTGAATGCGGTAAAGAACCACAATTTCATTGCCCAGATTGTCCATATAAAGCTAAACAGAAGATAACGTTAAAGGCCCATATTGCAGCTAAACATATGACCCTAGGTCATTGCGCATTAAGCCATTCATTGGTCCATATTATTCGTTTAACTCTTATGTTGATCGTAGCTTATGATTCCTTTGTAAATCGATATGCATGTTTATGTGGACGAACTTATAAATATAAAGAAGGGCTTTATAAGCATAAAAGATTTGAATGTGGTAAAGAGCCACAGTTTTCTTGCACTAAATGCCCATATAAATCATTTCATAAGGGAAATCTCAAAGCGCATATTATTGTCAAACATTCTAAATGTTTTAAGAAAATCAAATTGTCTTCAGTAATGAAACCCTCTGATGGTGTTTCAAATCAGATTCGTACGCCAAATACTAGATTTATATTACCAAAACCAGTGGAAGAACGGAATGTAATGACTAGCGAAAAAATCGCCACTCATTCAAGATTAGAAGTGAATAAAATGCCAGTTCGTGATGATAATTCTTTGCCACCTCAAAATGATTCGACGATTGTGGCAGCAAGCAGTCATATCATGGTGGCCAGCAGAGGATGTGAGAAAAAAATATCTTTTCTTCCTGAAGGCCAATTTTTAGCAATTCAGAGTCCCATGCCAGTTTTTATAAAGGGCAACGATTGGACGGAACAAAAGCAGAGACTCATTAATCCAGTAAACATACCAAGAATGCCGATGAATTATACAAGCACCTTCAAGAGAATATTACCAAAACCTCCACCTTGTGAGATGGTTGACGTACGTGGATTCGGTCCCGTTGAAGAACCACCACCGCCACAACAATCACGTCACAAGACCACTCCAGCGGTCAAAAAAACGGATAAAATGGTTGTGCCACAAAAACTCATTCATGTGTTACCAGAAAATGAGGAAAATATTGAATCTAAAGAACAGTTCATTTTACCAGATATGCCTGAGTCTGGACATATTCAGACAGTTCCTGTAAAACATATTTGCGACACTTGTGGCAGGGCTTACAAAAATAAAGGCCACCTTTCAAGTCATAAAAAATATGAATGCGGTGTTGAACCAAAATTTCATTGCCCACATTGCTCCTATAGAGCCAAACAGAAAGTTATGAATATTGCCAAGAGACATTTGTGTATTAAATGCTATAAAACGTACAAGAATAAACATCATTTGAAAAGGCACCAAACATATGAATGCGGCAAAGAGCCACAGTTTCATTGCCCTCATTGCCCATACAAGGCAAAACAGAAAGACTCCTTAAAGGCACATATTGCTGTTAAACATAAGCCTATTGTTGAATCTGGTAGATATGTTTGCAGCGCATGTAATAAATCTTACAAACATAAAAGCTTGTGGAAAAGGCATAGAAACTTTGAATGTGATGATGACGATGACGATGACGATATTACTAGATATACTTGTATGGCTTGTAATAAATCTTACAAACGTAGAACCCATTGGAAAAGACATCAAAATTATGAATGTGAAGTATTAGCACTTCCAAGATTTGTTTGTGATAATTGTCAAAGATCTTACAAAAATAAACGTCATCTGCAACGCCATCAAAAATACGAATGTGGAAAAGAGCCAAGTTTCAAATGTCCATATTGTCCATATAAAGCAAGACGAAAGGGAACTCTTGATACACATATTACGGCTAAACATGAATCTTCTTATTTGTAA
- Protein Sequence
- MSIGKVVMARHRCPTCGKSFKYKAGLYQHRKHDCGKDYHFYCPYCAYRCRRSEFLALEGDWREKEYPGVIGTTSNVNRKRKTVQNNAISGSLLTNVPVTKDGPVKYTCTACGKVYQHRQSLYNHVSYQCGREPQFACPYCQYRSRHKVNLKRHIATIHMVGLREQLGSNSVLSNEKFACNQCFRSYVHIQSLYKHKKFECGKEPQFHCPDCPYKAKQKITLKAHIAAKHMTLGHCALSHSLVHIIRLTLMLIVAYDSFVNRYACLCGRTYKYKEGLYKHKRFECGKEPQFSCTKCPYKSFHKGNLKAHIIVKHSKCFKKIKLSSVMKPSDGVSNQIRTPNTRFILPKPVEERNVMTSEKIATHSRLEVNKMPVRDDNSLPPQNDSTIVAASSHIMVASRGCEKKISFLPEGQFLAIQSPMPVFIKGNDWTEQKQRLINPVNIPRMPMNYTSTFKRILPKPPPCEMVDVRGFGPVEEPPPPQQSRHKTTPAVKKTDKMVVPQKLIHVLPENEENIESKEQFILPDMPESGHIQTVPVKHICDTCGRAYKNKGHLSSHKKYECGVEPKFHCPHCSYRAKQKVMNIAKRHLCIKCYKTYKNKHHLKRHQTYECGKEPQFHCPHCPYKAKQKDSLKAHIAVKHKPIVESGRYVCSACNKSYKHKSLWKRHRNFECDDDDDDDDITRYTCMACNKSYKRRTHWKRHQNYECEVLALPRFVCDNCQRSYKNKRHLQRHQKYECGKEPSFKCPYCPYKARRKGTLDTHITAKHESSYL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -