Basic Information

Insect: Triatoma infestans
Gene Symbol: hb
Assembly: GCA_011037195.1
Location: JAAEAF010014910.1:17590-27378[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0035 1.3 11.5 1.0 2 23 213 234 212 234 0.96

2 8 0.014 5.3 9.7 1.7 2 23 237 259 236 259 0.97

3 8 0.033 13 8.5 1.0 1 23 287 309 287 309 0.98

4 8 0.0017 0.64 12.6 3.1 2 23 317 338 316 338 0.97

5 8 7.6e-05 0.029 16.8 4.5 1 23 344 366 344 366 0.99

6 8 0.02 7.9 9.1 6.0 1 23 372 396 372 396 0.93

7 8 0.0005 0.19 14.2 0.5 1 23 639 661 639 661 0.96

8 8 0.0033 1.3 11.6 0.4 1 22 667 688 667 691 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0035	1.3	11.5	1.0	2	23	213	234	212	234	0.96
2	8	0.014	5.3	9.7	1.7	2	23	237	259	236	259	0.97
3	8	0.033	13	8.5	1.0	1	23	287	309	287	309	0.98
4	8	0.0017	0.64	12.6	3.1	2	23	317	338	316	338	0.97
5	8	7.6e-05	0.029	16.8	4.5	1	23	344	366	344	366	0.99
6	8	0.02	7.9	9.1	6.0	1	23	372	396	372	396	0.93
7	8	0.0005	0.19	14.2	0.5	1	23	639	661	639	661	0.96
8	8	0.0033	1.3	11.6	0.4	1	22	667	688	667	691	0.90

Sequence Information

Coding Sequence: ATGATAGTTTCAGCCGATATTTTCAATACGACAACACAATCAAATACAAATATGAATTGTGGGCTACAATATGATTCTAGACACAATGTTTTCCCGGGGCTTAATATGGACACCCATTGGATGGCACATCACGCTTTAGCAAATGTGAAGCAAGAACCGCGAGACGATGCGGAATATGGTTATGGGAAAAGTGATAAAGCTAGTTTTTCGTCACCATTAACACCACCAGGTTTGAATGCAACCTACAGCTTCCCAACACCACAATCAGAATATACAGGCTCCAGTTCACCAGGACCAGATACATACAATACCAAACAAACGGCCACAAATACCACACAATGTAGTGGTGGTATTGTCAGCGATGGTAGTAGCGGTGAAACAGCGTCCATTGATCCAATACCAACACCAAAATCAGATGGTGGTAAAAGTTCACCACGTCTAACGCCGCCTGGTTCAATACCATCGCCGCCtttacatcatcatcatcttcatgTTGATCACGGTGAAAAACATGACAATCAAGATGGCGGTTCACAGAGTTCGAATTCGGAAAATGAATTCTATGAAAATGGTGATTCACTTAGACGTTTACAGATGGCACTGCAGAGGACTGGTATGATGCCTGAAGAGAAACTACAATGCCCAATGTGTGAATACTCATGTAATATcagATCTCAGTTTAATGAACACCTGATGGCGCATGAGACTAAATGCAACATGTGCGACTTTAATGGAGAATCTTGTGATAAATTACGTGAACACATGAAAGTAGTGCACGACTGCGATGAAGATATGTGGGCCGATGATGAACCAGGTTTGAATACGCCAAAAGTAAATAGCCAAGGAAAAGTAAAAACGTTTCGTTGTAAGCAATGCGAATTTTCCGCTGtaacaaaattggaattttgggAACATTCTAGGACGCATATAAAACAAGAACGCTTATTAACATGCCCAAAGTGTCCTTTTGTTACTGAATATAAACATCATTTGGAATATCATTTAAGAAATCATTTCGGTTCAAAACCGTTTAAATGTGACAAATGTTCATACTCTTGTGTTAATAAATCAATGTTAAATTCACATTTAAAAAGTCACAGTAATATATATCAATTTAGATGCTCCGATTGTACTTATGCTACAAAATATTGCCATAGTCTCAAATTACATTTACGTAAATATGGTCACAGTCCAGCTATGGTATTGAATCCAGATGGATCACCAAATCCGCTGCCAATTGTGGATGTTTACGGTACAAGACGTGGGCCAAAACAGAAATCCAAACATGACAAACAACGATCCAGTTCACCGCAACAATCTCAATCGCAGCAACGATCTCAACAAAGTTCACCTCAAccacagcaacaacaacaacaacaacaggctcaacaacaacaaccgcAACAGCAAGTTGCAGCAATGCCATTGTTCAATCCTTACAGTTTACTACCTACACAAATGCcttattacaatatattgaacGGTTTTAGTCCATTTCCATTTGCCCAAGATATGAGAGTTgatgagaaaaataataatatagaaaaagaaGCCAGCACGGATGCATCAGAGTTTGCTGCATCACCATCAAAAGAGGAAACTAAAACACCATTAGATTTGACGTGTACAGAACGTGTAGACGATACACCACCGGAAACGCCAGTATTGAAGAATCGACGTAAAGGTAAAGCATTTAAATTGGAACGTATAGCGATAAGATTACAACAACAAAGCGAAGACGAAGAACCGGAACAATTGATCACTAAACCGGATATCTATATGGATCAACAGCAATGCAAATCACCGGATATTAAATCTTGTGATACAGATAGTGAACAACAAGAACCACAACCGCAACAacaactacaacaacaacaacaacaaaaaccaGATTTTCAGCATAAAATTGATGATTATAATTGTAGTTATTGTGATATATCATTTAAAGATATTGTTATGTATACAATGCATATGGGATACCATGGGTATCAGGATCCGTTTACATGTAATATGTGCGGACAACAGACATCAGATAAAGTTGCATTTTTCTTGCATATCGCTAGAACATcacattcataa
Protein Sequence: MIVSADIFNTTTQSNTNMNCGLQYDSRHNVFPGLNMDTHWMAHHALANVKQEPRDDAEYGYGKSDKASFSSPLTPPGLNATYSFPTPQSEYTGSSSPGPDTYNTKQTATNTTQCSGGIVSDGSSGETASIDPIPTPKSDGGKSSPRLTPPGSIPSPPLHHHHLHVDHGEKHDNQDGGSQSSNSENEFYENGDSLRRLQMALQRTGMMPEEKLQCPMCEYSCNIRSQFNEHLMAHETKCNMCDFNGESCDKLREHMKVVHDCDEDMWADDEPGLNTPKVNSQGKVKTFRCKQCEFSAVTKLEFWEHSRTHIKQERLLTCPKCPFVTEYKHHLEYHLRNHFGSKPFKCDKCSYSCVNKSMLNSHLKSHSNIYQFRCSDCTYATKYCHSLKLHLRKYGHSPAMVLNPDGSPNPLPIVDVYGTRRGPKQKSKHDKQRSSSPQQSQSQQRSQQSSPQPQQQQQQQQAQQQQPQQQVAAMPLFNPYSLLPTQMPYYNILNGFSPFPFAQDMRVDEKNNNIEKEASTDASEFAASPSKEETKTPLDLTCTERVDDTPPETPVLKNRRKGKAFKLERIAIRLQQQSEDEEPEQLITKPDIYMDQQQCKSPDIKSCDTDSEQQEPQPQQQLQQQQQQKPDFQHKIDDYNCSYCDISFKDIVMYTMHMGYHGYQDPFTCNMCGQQTSDKVAFFLHIARTSHS*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01301894;
90% Identity: iTF_01301894;
80% Identity: -