Basic Information

Gene Symbol
-
Assembly
GCA_011764245.1
Location
HIC:3019908-3059771[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 30 0.047 3.2 8.4 0.2 3 23 331 351 329 351 0.96
2 30 8.8e-07 6e-05 23.3 4.2 1 23 357 379 357 379 0.99
3 30 0.00062 0.042 14.3 0.4 3 23 387 407 385 407 0.98
4 30 0.0026 0.18 12.4 1.2 1 23 421 443 421 443 0.98
5 30 0.00011 0.0077 16.7 0.7 3 23 451 471 449 471 0.98
6 30 0.0076 0.52 10.9 2.4 1 23 477 500 477 500 0.97
7 30 0.00011 0.0078 16.6 1.8 1 23 506 528 506 528 0.98
8 30 5.2e-05 0.0035 17.7 1.1 1 23 534 556 534 556 0.98
9 30 0.53 36 5.1 4.0 3 17 564 578 562 587 0.85
10 30 0.0019 0.13 12.8 0.2 3 23 882 902 880 902 0.97
11 30 0.23 15 6.3 1.5 1 13 908 920 908 922 0.91
12 30 0.00027 0.018 15.5 3.7 1 23 924 947 924 947 0.97
13 30 2.2e-05 0.0015 18.9 2.3 1 23 953 975 953 975 0.99
14 30 5.2e-05 0.0035 17.7 1.1 1 23 981 1003 981 1003 0.98
15 30 0.0031 0.21 12.1 1.4 3 23 1011 1031 1009 1031 0.97
16 30 0.0017 0.12 12.9 3.7 3 23 1036 1056 1034 1056 0.98
17 30 0.0052 0.35 11.4 1.9 1 22 1062 1083 1062 1083 0.96
18 30 0.00022 0.015 15.7 0.5 1 23 1109 1131 1109 1131 0.98
19 30 0.23 16 6.2 0.7 1 18 1336 1353 1336 1353 0.92
20 30 3.2e-06 0.00022 21.5 2.2 1 23 1414 1436 1414 1436 0.99
21 30 5.6e-05 0.0038 17.6 2.1 3 23 1444 1464 1442 1464 0.98
22 30 0.0011 0.072 13.6 2.4 1 23 1470 1493 1470 1493 0.97
23 30 0.017 1.1 9.9 7.9 1 23 1499 1521 1499 1521 0.99
24 30 1.1e-05 0.00078 19.8 1.7 1 23 1527 1549 1527 1549 0.98
25 30 0.0031 0.21 12.1 1.4 3 23 1557 1577 1555 1577 0.97
26 30 0.0017 0.12 12.9 3.7 3 23 1582 1602 1580 1602 0.98
27 30 0.0052 0.35 11.4 1.9 1 22 1608 1629 1608 1629 0.96
28 30 0.45 31 5.3 0.1 5 20 1640 1655 1639 1656 0.93
29 30 0.062 4.2 8.1 0.1 1 21 1660 1680 1660 1681 0.94
30 30 9.2 6.2e+02 1.2 0.1 2 16 1689 1703 1688 1704 0.88

Sequence Information

Coding Sequence
ATGCCTCTGCAAGATTCTCGAGGGTGCGTCTCCGCCATGAAACTCGACCTCCTCCCAAAACTTTACGAACAGTTAAAGTTAAAAGTGTCTAGAAGGATGGATATAAAATACCTGACTCAAAACGTGAATGAAGCGCATGACGTGGAAGCGTGGTTTGGGAAGAAGTTAAAAGTCATTCTGAAAAGGGTGGATGAAGTAAAGCAGGAAAATTCAGAAGCAGAAAAGCACCAACAAGGTGAATCGCCTGAGTCAGCTGCTGCTGGATCCTTGCACTTTCCAAGTGTTCAAACTAATCGTATTCCTCAAGATTTAAGGAATATTCAGGATGTCGGAACTGTGACTAAACATGAAATTCTTGAAGGTTTCTCAGTGGTACCCATTAAATCAGAGCCCAGCCATACAGGTGTGGATATCATCAAAGATCGAATTAAATTCAAGGAACAACTTCAGCGTCAAGCAGCAAACAACGATGATGAAATGCAAGATGTAGAAACTGCGGCTAAACATGAAATTCTTGAAGGTTTCTCAGTCATACCTATTAAATCAGAGCCAAGCCTCATTCTTGTCGGTGACATGAAAGATCCAAATGAACTCAAGGAAGAACTTGTGCATGAAACAACAAAGGAGTTAAATGAAGATGATGAGTTGTGTGCCCCCTTGGTGATGACTGCGAACCTTGGGACCAGTCAGAGCTCAGAGTGTCACAAGATGGTGGACTGTACGGAAAAATTGGAGAACCCCTTTTCCTGTGCACACTCCTTCATTCCAGAGAATACTTGGAATAATCATGACAATCATTTTACTCATGAAAGACTTTATGCATGTATTCGCTGCAATGCCAATTTTCCTGATGAAAGAAAGCCTAGCAAACAGTTCAGAATATACGGTGGTGCAGAAACGTTTCCAATTAATGAATGCAGTTCATCATTTGCTAATGGATACAATATGGAAAGAAAAGCGAAAGAAATTTGCAGCAAAACCCTCTTTGGGTGCGCTCGCTGTAATGCAACATTTTCTGTAAAAGCGGATCTGGATCGGCACAAAGCATCGCATGCTGGAGACAAAGCCTATTCATGCACACACTGCAATGCAACATTCTCTCAAAAAAGTAGTTTGAATAAACATGTAAGAACACACACGACAGAAAAACCGTTTGGATGTGCACAGTGTAATACAAAATATACTCTGAAAGGCAATTTAATTGCACATTTGAGAACACATACTGGACAGCATATCAAAATACATACCGGAGAAAAACCATTCGAATGTGCGTTCTGCGATGCAACATTTTTGAAAAAAAATTACTTGACTCAGCATATAAGAACTCATACTGGAGAAAAACCGTTTGGATGTACACAGTGCAATAAAAAATTTGCTACAAGACCGGGTCTCAATCAACATATGATAAGACATACTGGAGAAAAACACTTTGAATGCACACATTGCAAAGCAACTTTTTTCGGGAAAAGTATTTTGAATACACATATGAGAAATATACATACTGGCGAAAGATCCTTCGCATGCTCACACTGCAATGCAAAATTTTATGGAAAAACGAATCTGATTCTGCACATCAGAACGCATACTGGAGAAAAACCCTTTGAATGCGCTCACTGCAATGCAAAATTTGCTGTAAAAAGTACTTTGACTGAACATATAAAAACACATATGAGAACAAAAACCTTCGGATGCACACACTGCAATGTAAAATTTTCTAATAAAGAACAGCTAAGAAATTTGAATCGACATGAAAAAATGCACGTGGGAAAAAATCCTTTGAGATGCTCAGACTGCAATGCCAAACTTATTAATAAAAAATCACTCTGCTCGTGCGCAGCAGCAGGACTAGCCAAAGGGCCAGGGCAGAGGGTGCACCGCACACGAGCGCCAAATAATGAAAAGAGGAGAAAGAAGGGAGGAAAGCTAAAGGACGAGAAGAAAATGAAAGAAATGAAGACAAAGAAATTAATACGAAAGGATGTCGGAACTGTGACTAAACATGAAATTCTTGAAGGTTTCTCAGTGGTACCCATTAAATCAGAGCCCAGCCATACATGTGTGGATATCATTAAAGATCGAAATAAATTCAAGGAACAACTTCAGCGTCAAGCAGCACACAACGATGATGAAATGCAAGTTGTAGAAACTGCGGCTAAACATGAAATTCTTAAAGGTTTCTCAGTCATACCTATTAAATCAGAGCCTAGCCTCAATCTTGTCGGCGACATGAAAGATCCAAATGAACTCAAAGAAGAACTTGTGCATGAAATAACAAACGAGTTAAATGAAGATGATGAGTTGTGTGCCCCCTTGGTGATGACTGCGAACCTTGGGACCAGTCAGAGCTCAGAGTGTCACAAGATGGTGGACTGTACGGAAAAATTGGAGAACCCCTTTTCCTGTGCACACTCCTTCATTCCAGAGAATACTTGGAATAATCATGACAATCATTTTACTCATGAAAGACTTTATGCATGTATTCGCTGCAATGCCAATATTCCTGATGAAAGAAAACCTAGCAAACACTTCAGAATATACGGTGGTGCAGAAACGTTTCCAATTAATGAATGCAGTTCATCATTTGCTAATGGATACAATATGGAAAGAAAAGCAAAAGAAATTTGCAGCAAAACCCTCTTTGGGTGCGCTCGCTGTAATGCAACATTTTCTGTAAAAGGGGATCTGGATCGGCACATGGCAACGCATGCTGGAGACAAAGCCTATTCATGCACACACTGCAATGCAACATTCTCTCAAAAACAAAAACGCTTTGAATGCACACATTGCAATGCAAAATTTTTTGATAAATTTACTTTGAATAGTCATATGAGAAATGTACACACTGGCGAAAGACGCTTTGAATGCTCACACTGCAATGCAAAATTTTATGGAAAATCGAGTCTGATTCAGCATATCAGAACCCATACTGGAGAAAAACCCTTTGAATGCGCTCACTGCAATGCAAAATTTGCTGTAAAAAGTACTTTGACTGAACATATAAAAACACATCTGAGAACAAAAACCTTTGGATGCACATACTGCAATGTAAAATTTCCTAATAAACAGCAACTAAGTCAACATAAAAAAGAACACAAGCCCTTTGGATGTACGCTATGCCATGCAAATTTTTCTCTAAGAAGTCATTTGATCGATCATATGAAAACACATACTGGAGAAAACCCCTTTCAATGTGCGCACTGCAATAAAAAAAATTCTAAAAAAGGTAATTTGAAGGAACATATAAGAAGAGAGACTGGCGAGAAACCGTTTGAATGCACACACTATCTGGAGTGTCATATCAGAACGCATACTGGAGAGAAACCCTTTGAATGTGTACAATGCGATGCAAAATTTTCTTTAAGAGGAAATTTGAATCGACATGAAAAAATGCACGCAAATTCAGAATCAGAAAAGCAACAACAAGGTGAATTGCCTGAGTCAGCTGCTGATGGATCCTTGCACTTTCCAAGTGTTCAAACTAATCGTATTCCTCAAGATTTAAGGAATATTCAGGATGTCGGAACTGTGACTAAACATGAAATTCTTGAAGGTTTCTCAGTGGTACCCATTAAATCAGAGCCCAGCCATACATGTGTGGTTATCATGAAAGATCGAAATAAATTCAAGGAACAACTTCAGCGTCAAGCAGCAAACAACGATGATGAAATGCAAATTGTAGAAACTGCGACTAAACATGAAATTCTTGAAGGTTTCTCAGTCATACATATTAAATCAGAGCCTAGCCTCAATCTTGTCGGCGATATGAAAGATCCAAATGAACTCAAGGAAGAACTTGTGCATGAAACAACAAACGAGTTAAATGAAGTTGCTGAGTTGTGTGCCCCCTTGATGATAACTGCGAACCTTGGGACTAGTCAGAGCCCAGAGCGTCACAAAATGGCGAACTGTAGGGAAAGATTGGACAACCCCTTTTCCTGTGCACTCTCCTTCATTCCAGAGGATACTTGGAATAATCATGACAATCATTCTACACACGAAAGACCACATGCATGTTTTTACTGCAATGTCAATTTTCCTGATAAACGCAATCTTAGGAAATACTTCAGAATATACCGTGGTGAAGGAACGTTTCCATGCAATGGTTGCGTTTTATCATTTGCTGCTGAAAACAATATAAACAGAAAAATGAAAGATATTTGCAGCAAAAACACCTTTGGATGCGCTCGCTGTAATGCAACATTTTCTCAGCATATCAAAATACATACCGGAGAAAAACCATTTGAATGTACAATCTGCGATGCAACATTTTTTACAAAATTTTACTTGACTCAGCATATGAGAACTCATACTGGAGAAAAACCGTTTGGATGTACACAATGCAGTAAAAAATTTACTACAAGACAGGGTCTCAATCGACATATGATAAGACATACTGGAGAAAAACGCTTTGAATGCACACATTGCAATGCAAAATTTTTTGATAAACTTACTTTGAATAGTCATATAAGAAATGTACACACTGGCGAAAGGCGCTTTGAATGCTCACACTGCAATGCAAAATTTTATTGTAAATCGAGTCTGATTCATCATATCAGAACGCATACTGGAGAAAAACCCTTTGAATGCGCTCACTGCAATGCAAAATTTGCTCAAAAAAGTACTTTGACTGAACATATAAAAACACATCTGAGAACAAAAACCTTTGGATGCACATACTGCAATGTAAAATTTCCTAATAAACAGCAACTAAGTCAACATAAAAAAGAACACAAGCCCTTTGGATGTACGCTATGCCATGCAAATTTTTCTCTAAGAAGTCATTTGATCGATCATATGAAAACACATACTGGAGAAAACCCCTTTCAATGTGCGCACTGCAATAAAAAAAATTCTAAAAAAGGTAATTTGAAGGAACATATAAGAAGAGAGACTGGCGAGAAACCCTTTGAATTCACACACTGCAATGCAAAGTTTTCTGGAAAAGCGAATCTGGAAACGCATACTGGAGAAAAACCCTTTGAATGTGCACAATGCGATGCAAAAATTTCTTTTAGAGGAAATTTGAATCGACATGAAAAAATGCTCGTGGGAAAAAATCCTTTGAGATGCTCAGACTGCAATGCCAAACTTATTAATAAAAAATCACTGGCAGGACTGGCCAAAGGGCCAGGACAGAGGGCGCACCGCACACGAGCGCCAAATAAT
Protein Sequence
MPLQDSRGCVSAMKLDLLPKLYEQLKLKVSRRMDIKYLTQNVNEAHDVEAWFGKKLKVILKRVDEVKQENSEAEKHQQGESPESAAAGSLHFPSVQTNRIPQDLRNIQDVGTVTKHEILEGFSVVPIKSEPSHTGVDIIKDRIKFKEQLQRQAANNDDEMQDVETAAKHEILEGFSVIPIKSEPSLILVGDMKDPNELKEELVHETTKELNEDDELCAPLVMTANLGTSQSSECHKMVDCTEKLENPFSCAHSFIPENTWNNHDNHFTHERLYACIRCNANFPDERKPSKQFRIYGGAETFPINECSSSFANGYNMERKAKEICSKTLFGCARCNATFSVKADLDRHKASHAGDKAYSCTHCNATFSQKSSLNKHVRTHTTEKPFGCAQCNTKYTLKGNLIAHLRTHTGQHIKIHTGEKPFECAFCDATFLKKNYLTQHIRTHTGEKPFGCTQCNKKFATRPGLNQHMIRHTGEKHFECTHCKATFFGKSILNTHMRNIHTGERSFACSHCNAKFYGKTNLILHIRTHTGEKPFECAHCNAKFAVKSTLTEHIKTHMRTKTFGCTHCNVKFSNKEQLRNLNRHEKMHVGKNPLRCSDCNAKLINKKSLCSCAAAGLAKGPGQRVHRTRAPNNEKRRKKGGKLKDEKKMKEMKTKKLIRKDVGTVTKHEILEGFSVVPIKSEPSHTCVDIIKDRNKFKEQLQRQAAHNDDEMQVVETAAKHEILKGFSVIPIKSEPSLNLVGDMKDPNELKEELVHEITNELNEDDELCAPLVMTANLGTSQSSECHKMVDCTEKLENPFSCAHSFIPENTWNNHDNHFTHERLYACIRCNANIPDERKPSKHFRIYGGAETFPINECSSSFANGYNMERKAKEICSKTLFGCARCNATFSVKGDLDRHMATHAGDKAYSCTHCNATFSQKQKRFECTHCNAKFFDKFTLNSHMRNVHTGERRFECSHCNAKFYGKSSLIQHIRTHTGEKPFECAHCNAKFAVKSTLTEHIKTHLRTKTFGCTYCNVKFPNKQQLSQHKKEHKPFGCTLCHANFSLRSHLIDHMKTHTGENPFQCAHCNKKNSKKGNLKEHIRRETGEKPFECTHYLECHIRTHTGEKPFECVQCDAKFSLRGNLNRHEKMHANSESEKQQQGELPESAADGSLHFPSVQTNRIPQDLRNIQDVGTVTKHEILEGFSVVPIKSEPSHTCVVIMKDRNKFKEQLQRQAANNDDEMQIVETATKHEILEGFSVIHIKSEPSLNLVGDMKDPNELKEELVHETTNELNEVAELCAPLMITANLGTSQSPERHKMANCRERLDNPFSCALSFIPEDTWNNHDNHSTHERPHACFYCNVNFPDKRNLRKYFRIYRGEGTFPCNGCVLSFAAENNINRKMKDICSKNTFGCARCNATFSQHIKIHTGEKPFECTICDATFFTKFYLTQHMRTHTGEKPFGCTQCSKKFTTRQGLNRHMIRHTGEKRFECTHCNAKFFDKLTLNSHIRNVHTGERRFECSHCNAKFYCKSSLIHHIRTHTGEKPFECAHCNAKFAQKSTLTEHIKTHLRTKTFGCTYCNVKFPNKQQLSQHKKEHKPFGCTLCHANFSLRSHLIDHMKTHTGENPFQCAHCNKKNSKKGNLKEHIRRETGEKPFEFTHCNAKFSGKANLETHTGEKPFECAQCDAKISFRGNLNRHEKMLVGKNPLRCSDCNAKLINKKSLAGLAKGPGQRAHRTRAPNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-