Basic Information

Gene Symbol
ZNF275
Assembly
GCA_036026315.1
Location
JAYRCB010000363.1:3331951-3334533[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0041 0.4 11.8 0.7 1 23 168 191 168 191 0.94
2 10 0.54 53 5.1 1.7 1 23 217 240 217 240 0.94
3 10 0.12 12 7.2 0.2 2 19 309 328 308 330 0.93
4 10 4.2 4.1e+02 2.3 0.6 2 23 373 395 372 395 0.85
5 10 3.7e-08 3.6e-06 27.7 2.3 1 23 401 423 401 423 0.97
6 10 1.6e-05 0.0016 19.3 1.0 2 23 439 461 438 461 0.94
7 10 3.7e-05 0.0036 18.2 0.7 1 23 467 489 467 489 0.98
8 10 0.0043 0.42 11.7 2.1 1 23 495 517 495 517 0.98
9 10 0.0002 0.019 15.9 2.3 1 23 523 546 523 546 0.98
10 10 0.027 2.6 9.2 1.5 1 23 553 575 553 575 0.98

Sequence Information

Coding Sequence
ATGAATGAGCAAACAAATACAAGCAATTCTTCTTATCAGAGCTATGAGATAAACGGTACCCAGTTTATCTTACAGACTCTATCAGATTCAATGGATACTTTAGTAAAAGTAGCATCAACCTGTGATGAGGATGAGGCTAGTGTTAACTATGTCGAGGAAGCAACACAACTTGAGCACGAGGAAGAATCGATCCCTCTAGTTTGTTTAGATGGCCAGGTGTATGCATTTAGAAATGGTGAACTTCAAGAACTCGATCTCAGTCAGCTTGTAGATCGAAATGATTGTCAAGACGGCTCAATAGTAATATCAAGAAATGTGCATAATAACGATGATTCAGAATGTGCAGTCATTACAGAGTACATATCTGAGGATAATGTTCCAATTGAAAATACAGAGATTAGTCATGAAGAAGAATACGAAGTTGTATTAGACAGAAATGAGAAATTGATTGTTGGCAAGGAGAGTCTGAATGCGAATGATTTTGTCGAGGTTGTCACAGCTTTCAAGTGTAAAATCTGTCCTTACACAACGCAAGACAGAACGCAGTTATTGGAACATTTTGAAAGTGTACATGTTAATCCATTAACAGAATCACAGaaaaagaaagaggaagaagagctCAAATCTGGAAATGACGTTAAGCTGGTTTATATGTGTGGAGAATGCTCCAATTGTTTTCCAACGATCGAAGATTGTCGAGAACATATGATAAATGATCATCAGCTTACGGATCGTGGAACGGATAAAAACATCAAAGAAAATCCAGCGCATCGTGTCGAACAGTCGGAATCATTCGTATCACCTTCAAATGATCTCCTTGCCGATAGTGACGTATCGAAGGAACCACAACCAAAAGTGCAGAAAGAATCACATAATGGCTACGTAATTGATAAAAAGACCGTGGAAGTAAAGGAGCGAAATATTAAATGCAGCTTCCGGGGATGTCCGTACAAGTTTAGCACAGAAGAGAAGATGCAGCAGCACGCAGTGTGCCATGCGGAATCgcaaaatgcaaatttatacAAGTGCAATCTCTGTCGAGACATAAAATTCGCTAAGTGGAGACCGTGTAGTCTTCACTTATGGAAGAAACATCAAATTGATATTGATCTTCTATCTTGCAAGGTCTGCAACACCTACAAAAGTGCCACCATGGTGAAGATGCTGACGCACATGCGAGTGCACAGTGACAATCGCGAATACGAATGTCCAGAATGTGGAAAATGTTTCAAACAGTCAAGCCAATTGCGAAATCATCGCGTTATGCATTTGGATCGTAAAACTAGCGAGGTACCACGTTGGTATACCTCGAAGACTTGTGAAATTTGCGGAAAGACTTATGCAGATTCCAAGTGCCTCAAGAATCACATACAGGCAGTACATTCGAAGCTGCGTCCATACGTTTGCAACGTGTGTGGACACTCGAGCGCGCGTAAGGCTATGTTGCAGATGCACCTGCGACAACACACTGGTGACAAACCTTTCAACTGCGAACTTTGCGAATACAAAACTGGAGATCATAATTCACTTCGTCGACATATTATGAGACACACAGgcGTGAGGCCATACAAATGTCCGCACTGTCCCTATTCGGCTATACAGAGTAACAGTTATAAGAATCATTTGCGATCAAAGCATCCGTTGCTCTCAGGATTATACACGTGTGATTTGTGCCAATTCAAAacagttaaaaaagaaagttatatGCAGCACGTTCGCGACCACGAAAAAGGTCTAATCAAAGTGCCCACGCAGAAGAAagATGACGAGAACGTCGAGGTCTTCCCTGGAAATATAGCAGCTGCTCAATTGATCTACAGTTGCTTAGGCGCATTTTCCAAAGTTGGAAAAACAATAGAAGCGAATCTAATGTCTTCCTCGACTTCGGCCGACGGTACTTCGCAGACAATTACAATACAGATACCGTCCAAGGATCTAGAGGGATCCTTACCAACGAGCAATGAAAATCCGAAGAATAATGCGTTGATCGAGCAGGAGGATGAGGAGACGATGCATTGTTTTCTAAAGATTCCacgagaggaagaagaaaacattGATACCGGTGGTATCACGATACCAGCCGAGTCTGAAGATCCAACAGGATCTAATATGAATGTcgacaattga
Protein Sequence
MNEQTNTSNSSYQSYEINGTQFILQTLSDSMDTLVKVASTCDEDEASVNYVEEATQLEHEEESIPLVCLDGQVYAFRNGELQELDLSQLVDRNDCQDGSIVISRNVHNNDDSECAVITEYISEDNVPIENTEISHEEEYEVVLDRNEKLIVGKESLNANDFVEVVTAFKCKICPYTTQDRTQLLEHFESVHVNPLTESQKKKEEEELKSGNDVKLVYMCGECSNCFPTIEDCREHMINDHQLTDRGTDKNIKENPAHRVEQSESFVSPSNDLLADSDVSKEPQPKVQKESHNGYVIDKKTVEVKERNIKCSFRGCPYKFSTEEKMQQHAVCHAESQNANLYKCNLCRDIKFAKWRPCSLHLWKKHQIDIDLLSCKVCNTYKSATMVKMLTHMRVHSDNREYECPECGKCFKQSSQLRNHRVMHLDRKTSEVPRWYTSKTCEICGKTYADSKCLKNHIQAVHSKLRPYVCNVCGHSSARKAMLQMHLRQHTGDKPFNCELCEYKTGDHNSLRRHIMRHTGVRPYKCPHCPYSAIQSNSYKNHLRSKHPLLSGLYTCDLCQFKTVKKESYMQHVRDHEKGLIKVPTQKKDDENVEVFPGNIAAAQLIYSCLGAFSKVGKTIEANLMSSSTSADGTSQTITIQIPSKDLEGSLPTSNENPKNNALIEQEDEETMHCFLKIPREEEENIDTGGITIPAESEDPTGSNMNVDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01131102;
90% Identity
iTF_00254627;
80% Identity
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