Basic Information

Gene Symbol
RREB1
Assembly
GCA_036026315.1
Location
JAYRCB010000379.1:626295-633250[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00062 0.06 14.4 0.0 1 23 63 85 63 85 0.98
2 15 0.0002 0.019 16.0 0.3 1 23 99 121 99 121 0.98
3 15 2.6e-07 2.5e-05 25.0 1.3 1 23 127 150 127 150 0.98
4 15 0.12 11 7.2 0.2 1 23 243 267 243 267 0.92
5 15 0.08 7.7 7.7 5.4 2 23 273 295 273 295 0.95
6 15 1.1 1.1e+02 4.2 0.3 1 19 351 369 351 371 0.94
7 15 0.22 21 6.4 0.1 1 23 485 507 485 507 0.96
8 15 1.9e-05 0.0018 19.2 0.3 1 23 516 538 516 538 0.98
9 15 0.0014 0.14 13.2 2.8 1 23 544 567 544 567 0.97
10 15 0.00052 0.051 14.6 3.0 1 23 953 976 953 976 0.97
11 15 0.00075 0.073 14.1 0.1 3 23 1248 1268 1246 1268 0.97
12 15 0.0047 0.46 11.6 2.2 1 23 1335 1359 1335 1359 0.97
13 15 6.2 6.1e+02 1.8 2.5 1 23 1445 1468 1445 1468 0.86
14 15 0.013 1.2 10.2 0.4 2 23 1519 1540 1518 1540 0.94
15 15 1.5 1.5e+02 3.7 8.2 1 23 1546 1568 1546 1568 0.98

Sequence Information

Coding Sequence
ATGCGGTCAGAACGACGCTCGAGGTCCTTGATAAATGTTATTGTCCCGGCTTCTACATCCCTGGTCAGTACAATGTGCGGTTTTGTGATTACAGTGACCGCTGACAGTGGACCGGATCAGCGACAGACCAGCGAGACTCAGACGGATGCTGGATCTTCGCCATTGGTCGAGCATCCGGAAGGAACGTATCCTTGTCCTGCATGCCCTACAGTACTCTCAACCTCCAGGGAACTAACGAATCATCTTCGTGGTCACAATTCACCACGCAGTACGGATTGCAGCGGCGAGGAGGACTATTCCTGCGGGGTCTGTCACAAGGTTCTTAGCTCTGCCAGTTCTCTCGATCGGCACGTGCTCGTTCACTCGGGCGAAAGGCCGTTCAAGTGTAAATACTGCGACATGGCCTTCACCACCAATGGAAATATGAACAGACACCTCAGGACGGCACATCGTGCGCTTTCGCCTCATAGTTGCACGGATTCCGAAGGGAGTAGCGATTCGGAAAAGCCTGTTAAGAGACGTCGCATCGAAGAGTACAATAATAACGAGATTGCCAAACGCAATTCTCCGGATCTCATTGAGAAACATAAATCTCCCAGCATGACCATTAACAAGAGGAAGTCGCTGGATTCTACGGACGAGGTTGAGTCACTGCGCAGGCACAAGATACTCCTGAACAGTTCCAGAACTGAGACTAAGAGCAACGTCTACGAGGACATGGCTGTTCATAATTGTCAAGTGTGCGGAAAACAGGATTTCGCGACTGCTGGTCTTCTGGAGGCTCATCTCGAGCGTAACCATCCTGAGGTGTTGGCGAAATGCGATATGTGCGATCTCTCGTTCAAGAATCATCGCGTGCTCAATCATCATCGGTTCATGAcacattttaatgaaaattcgattAACAATAGTTCACGGAACCTCAGGAACTCTGTGGTAGGTTTCGATGATTTGACATTCGTCGATTTCTCAGCTGACAAATTCCCGGCCATCGCCAGGGCCGTTTGCGAACAGTCTGTTCATAGACCAGCTTCCGGGGAAGTTACTAGGTTCCAATGCGCCAAGTGTCTCAGGGCGTTCCCTTGCAGATCGGCCCTGGAGGCGCACGAGTCTGACTGTGGGATACCCAATTCTCAGAGCAGAACCCATGGCGAGGATCAGTCTAGGAGGGACAACTTCTTTGCTGGTCTTGATCTTCAAAACAAGGCTGCTCTCGCTGAGGCCAAGGAAGGCAAGGATCTGGCTGACATACAGAGCATCATTTCCATGACCTCTGGACCCATTCTACAGAACTTTCCTAGGTCCGATGCCAGCACACCGGATAACAGTATCAAAATCAATCCCAACCTTGGATCCTCCGGTTCATCCGGCACACCCTCCTCAGAGTACCACGAAGAAGAAGCACAGGACGCCTTCGCGGCTGAGTTCAGGAAGATGAAACTCAAAGGAGAATTTCCATGCAGACTTTGCACCGCAATATTTCCCAATCTTCGAGCTCTCAAGGGTCATAACCGGGCGCATATGAATGTCGGTCCAGGTATGCCCTATCCATGTAATATGTGCCCATACACGAGCACCGATAAAGCTACCCTTATCAGACATTTAAGGTCGCACAATGGTGATAGACCTTACGAATGCTCTCTGTGTAATTATGCTTTCACGACCAAGGCCAACTGTGAAAGACACGTTCGCAATCGTCATGGTAAGCTCACCCGTGAGGACATTAAGAGCGTTCTGATATATCATCCCAACGAAGACTCCACAAACGACACCGTCGATCGCACATCTCCCAGGGCCATCTCTAGGGAGGATGCTCGTAAAACTCTAGTCTATCACAGCGAACGCGACGAAGGCAtccatcagcatcatcattactCTACGTTATCTATGTCCACTGAGCCTAAGTCTGAAATCCGAGTTATCGAGGAGGCCAAGCTTCGTCAGCCGGGAATACCCTCACTCTTCGCGGTGAATCACTACGAAAATTCGGAATTCTTCTCTAGGCCAACGAGTATCCAATCCATAGAACTCGGAAGGCATTCCGAGGAGCCGGAGAAGGGTCAGGAACTGTTAGGAAAGCACAGTTACTCGAAGGACGATGAAGACGATCAAGACACCAGGTCGTCGGATGAAAGCGTGTCTCTAGTCAGCGAAACCAAATCCGAGGTGCACCAAAGAAATCAGGATGGTCCTATCGACTTGAAAAAGACTATCGGAGACTCTGGAAACGTGGTCGATTCCGGAGTTGAAGAAGCTCCCCTTGATCTCTCCATGGATGCCCTTGATCTCAGAAAAAGGTCCAGGAGCAACGAAGCCGATCAGCCTAGTTCGTCCGAAGACTACTCCAGGAATCCTAAGGACTTCTATAACGCTACGAATCAACTTTTATTGACCCAAGCTCTTCTCAAGGCCGGACAGGCTGGTAATCAGCCTAACTCCTTGGAAGCTCTATATGCAAACGCTCATCTgatttatcgaaattttgGCACCTTCCCACCAGGTACTGGCCTGATACCGCCTTATCTCCTTAACCCGCATTTATTTGGCCATGATTTTGCCATGAAGGACAGAATCCAGAAGGAACTGGTACGAGGCCTGCAGCTCACCAGTGGTGGAACTCTCGTGGAACCATCCGGATTTGTGTCAAACTTTCCTCAAGGACGGGAATTATCAGCGCATACAGCTACTGACCAAACTGATTACTCCAAACTGATTTCATCCCAACTTAATAACAAGGTCTCGGTGCCACGTGAGAAGTTAGAAAACTCTCCCAGCTCGAATTCTGTCAAGATGGTCATAAAGAATGGGGTCCTCATGCcaaaacaaaagcaaaggCGATACAGAACCGAGCGACCGTTCACCTGCGAACACTGTTCGGCCAGGTTCACCCTCAGGAGTAACATGGAAAGACATATTAAGCAACAGCATCCTCAGCACTGGAGCCAAAGACCACGAGGTGGTCATTCCACAAGAGGTCGACCTCCAGCGAATCCTCCGACCTTGTTACAAAATCTTGGACAATCCAGCTTGTCCCAGCAGGTACAGCAGCAATATCAAAACATATTACCAAAGATGGGACAGAATGTGAGTTCGGAGTACGGAAAGCACGCTATTTCCGATCAAGTGAAGTACGCTATACTGGCACAGCAGTTGAAAGGTAACAGAGTAGAGGAAAATGACACCGACGAGGAGCTGATAATCGACGAAGGTCCAACCGGAAGAGAAACACCGGATAACCATCGTGAGAACGAACAGCAGCCTACCAGTCTACTCAGAGATCAGTCACAGAACAACGAAGAAGACGACGAGCACGATGCCAAGGGCAAAATAAAGTCTGAAATAAACGAGTCCAAGCCGGAAGTTGAGACTAACGTGGATGACGATGATCTAATATCCGAGAACAGTCTGGTCAAGTCAGAAATGCCAGATGAGATGGGAAAGAGAAGCGAATCGTCACGAGAGGACGAAAACGAAAGAACCGAAGATGGCACTGTTGATCTTGCTAGTGTTTCCAAGCTGCTGGACAATGCTTCCCAACAGTATCAACAGTTTCAACCTCAGTATCTTAGCGACGAGGAAGGTCTCGTCGCTTCTACTAGCGACTGTAACAATTCGGGTAGCGACGAGAAATCCGATTCTGGAAATTCAGTTAATTCCGGGACATCGACCTCatccaagaagaagaagaaaaagaagaagaagaaaaaatctgCATACTCGATGGCGCCGAACAGAGTGATCTGTCCTTATTGCGAGAGGCCTTTCCCATGGACGTCCTCCCTGAGGAGACACATTCTCACTCACACTGGACAGAAGCCTTATCAGTGTATACACTGCTCCCTTCTATTTACGACAAAGTCAAACTGCGATCGTCATCTTTTACGAAAGCACAAGACCAATCCCCACAAGATTCGTCGAGCAAGAAACTCATCGTCCCCGGAAGCGTCAAATATTCCAGCAAACAGCAATAGCTTCTCAATGAGAAACGTCCCGGAGAGACCCTACAAGTGCAACCAATGTCCAAGCTCTACCTTCTCCACTCTGGGAAACTTGAAGAAGCACCGATCAACGAAGcacatagataaaaaaaacaaatccagATGCAACACCCCCTTGAGCGAATCCCAAAACAGTCCGCAGAGTTCAGGGAAGCATAACGATCAGAGTGGATACGAGAGTCAGTCTTCAAGTATTTCTGAAAACATGCAAAATTCGCCACAGAACGTCCCCGTTATCAAATTGACAACCAGTACGACCTCCTCCTCGATCAACGACGCGTCTCGTTCACGAAAAACATCTCCAAGATCCTCACCAGGACCCGCCGAAGCGCCTTTCAAGTGTCACCTGTGCGACAGCGGCTTCGCAGAGCGTCAAGATTGTCTTGAGCACATAAAGGACAATCACAAAAGGTCCTACGAGATGCTGGTGGCCAAGGGTGCGCTGGACATGGATATAGAAGCAGCAGAGGATCAGCAGCAACCTCTGGTACATCAGCAGGCGAGCGACGGTGAAGAGAAACGTGGAAAATTTCCTGACTACAGTAATAGAAAGGTAGTTTGTGCGTTCTGCATGCGCAGATTTTGGTCTGCAGAGGATCTTCGTCGTCACATGAGAACTCACACCGGGGAGAGGCCATTTTCCTGTGACATTTGCTGTCGCCGATTCACTCTGAAACACAGCATGCTGAGACACAGGAAGAAGCACGAATCCGTCGACTCTCCTATGTACGTGGGTACGAGTGGAGATGAAGAATCCGTAGCGAGTCAACCACCCACGATCACACCGAGAAGTCAGCAGCATCCAGCACTCGTAATGTCGTCCACCAGTGATAACAGATTGCGAGAGCGCGTATCTCTGCCCACTGTGGAGGCTGTAGCTACAGCGGATGCTGCTCCCAGTGGTCTCATGAGGTACAACGCATACGAGAACCTCACTACTCTGACTGGGCAGCTGACTACTGTTCAGCAAAGTGGAAATCTGGATGTTCCTGAAAATTCAGAGAACGATCTTATCTCGAATCTCCTTGGCATTCGCGATAAGAGCATTATAGACAGAGTGCTTCAGGCATCGGCTGACGACGCGGCCAAATTGCTCGGAGTCAAAAGAAACTAA
Protein Sequence
MRSERRSRSLINVIVPASTSLVSTMCGFVITVTADSGPDQRQTSETQTDAGSSPLVEHPEGTYPCPACPTVLSTSRELTNHLRGHNSPRSTDCSGEEDYSCGVCHKVLSSASSLDRHVLVHSGERPFKCKYCDMAFTTNGNMNRHLRTAHRALSPHSCTDSEGSSDSEKPVKRRRIEEYNNNEIAKRNSPDLIEKHKSPSMTINKRKSLDSTDEVESLRRHKILLNSSRTETKSNVYEDMAVHNCQVCGKQDFATAGLLEAHLERNHPEVLAKCDMCDLSFKNHRVLNHHRFMTHFNENSINNSSRNLRNSVVGFDDLTFVDFSADKFPAIARAVCEQSVHRPASGEVTRFQCAKCLRAFPCRSALEAHESDCGIPNSQSRTHGEDQSRRDNFFAGLDLQNKAALAEAKEGKDLADIQSIISMTSGPILQNFPRSDASTPDNSIKINPNLGSSGSSGTPSSEYHEEEAQDAFAAEFRKMKLKGEFPCRLCTAIFPNLRALKGHNRAHMNVGPGMPYPCNMCPYTSTDKATLIRHLRSHNGDRPYECSLCNYAFTTKANCERHVRNRHGKLTREDIKSVLIYHPNEDSTNDTVDRTSPRAISREDARKTLVYHSERDEGIHQHHHYSTLSMSTEPKSEIRVIEEAKLRQPGIPSLFAVNHYENSEFFSRPTSIQSIELGRHSEEPEKGQELLGKHSYSKDDEDDQDTRSSDESVSLVSETKSEVHQRNQDGPIDLKKTIGDSGNVVDSGVEEAPLDLSMDALDLRKRSRSNEADQPSSSEDYSRNPKDFYNATNQLLLTQALLKAGQAGNQPNSLEALYANAHLIYRNFGTFPPGTGLIPPYLLNPHLFGHDFAMKDRIQKELVRGLQLTSGGTLVEPSGFVSNFPQGRELSAHTATDQTDYSKLISSQLNNKVSVPREKLENSPSSNSVKMVIKNGVLMPKQKQRRYRTERPFTCEHCSARFTLRSNMERHIKQQHPQHWSQRPRGGHSTRGRPPANPPTLLQNLGQSSLSQQVQQQYQNILPKMGQNVSSEYGKHAISDQVKYAILAQQLKGNRVEENDTDEELIIDEGPTGRETPDNHRENEQQPTSLLRDQSQNNEEDDEHDAKGKIKSEINESKPEVETNVDDDDLISENSLVKSEMPDEMGKRSESSREDENERTEDGTVDLASVSKLLDNASQQYQQFQPQYLSDEEGLVASTSDCNNSGSDEKSDSGNSVNSGTSTSSKKKKKKKKKKKSAYSMAPNRVICPYCERPFPWTSSLRRHILTHTGQKPYQCIHCSLLFTTKSNCDRHLLRKHKTNPHKIRRARNSSSPEASNIPANSNSFSMRNVPERPYKCNQCPSSTFSTLGNLKKHRSTKHIDKKNKSRCNTPLSESQNSPQSSGKHNDQSGYESQSSSISENMQNSPQNVPVIKLTTSTTSSSINDASRSRKTSPRSSPGPAEAPFKCHLCDSGFAERQDCLEHIKDNHKRSYEMLVAKGALDMDIEAAEDQQQPLVHQQASDGEEKRGKFPDYSNRKVVCAFCMRRFWSAEDLRRHMRTHTGERPFSCDICCRRFTLKHSMLRHRKKHESVDSPMYVGTSGDEESVASQPPTITPRSQQHPALVMSSTSDNRLRERVSLPTVEAVATADAAPSGLMRYNAYENLTTLTGQLTTVQQSGNLDVPENSENDLISNLLGIRDKSIIDRVLQASADDAAKLLGVKRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01474941;
90% Identity
iTF_01474941;
80% Identity
-