Tman003870.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Trabutina mannipara
Gene Symbol
BCL11A
Assembly
GCA_900080175.1
Location
FKYK01009068.1:389-3067[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 5 2.9e-08 2.4e-06 27.7 2.8 1 23 375 397 375 397 0.99
2 5 3.9e-06 0.00032 21.0 5.6 1 23 403 425 403 425 0.99
3 5 1.2e-07 9.6e-06 25.8 2.9 2 23 780 801 779 801 0.97
4 5 8.3e-06 0.00069 20.0 3.3 1 23 807 829 807 829 0.99
5 5 5.3e-05 0.0044 17.4 0.4 1 22 837 858 837 858 0.97

Sequence Information

Coding Sequence
AtggtgttgtttttgttttttctgttcacAGAACCAAGTTACTACATATGTTCAACGTGCAAACAGAGACTGCATTCGGCGTGGCGGCTAGTCCAGCATTGCCAGAACAGTCACGGTATAAAAATCTATTTGGAATCGTCATCGTCGACGAGTTCCAGTCCATCGGCGACGAATTGCGCGCCGCCTCCTAAAAGCGCGAGTAATAATAATcattcttcgtcgtcgtcatcgtgtTCGAGATTTTCAGCTTCTTCGTCGTCGAACTGTTCGGGAAATTCTTCGAGCGGCGCGGGCGGCGTACCGGGAAACGGCGGCGGCGCCGGTAACAGCGTCGGTTCATTGGCAGCATCTTCGTTACCATTACCTTCGGCTTCAATATCGTCGCGATTACCTTTACTGCCGCCTACCTCGACGTCGATGGTCGATCCGCGTAATCCGTTCGGCGTCGGAGGCCTGCTGCGATTACCTCTGAATGATCCAACGCGCCATCATCAGTTTCCCACCACGCTGGGTGGACTTCACGGCGGCGGTACCGGAGCTAATTCGCCGGTATTCGCCAGGCCTTCTTCTAGTCATCAGGATAATCATTTCCGTATGGAGCAGATCGTGTCCGAgcaatttcgtttaaattcgCATCACAGCATGGGCCTGGCTGCTGCGGCCGCCGCTGTCGCGGCCAGCGCCGCAGCCGGAATACCGCCTCCGCATTCGCCTTACCCGCCGGTCGATCGGCCGCCCAGCAATAGCATGCATACGAACGGGCCGCGATCGATGATTCCACCGCCACCTTCATTGTCACTACCGTTAGAACCGCAGTTGGATTTTTACTCGCAACGGTTACGCCAGTTGGCCGGCACCACTAGTCCGGGGGTAGCGAACGGGCCTAATTCGCTGTCGCCCAGAAAGCTCACGCCGCCCTTTACCAGCCCCGGTAACTCGCAGCCGTTACCTCCGAGTCGATCCTCGTCTACAGATAATTCGGCCAACGATTCGCTAGATTTGTCGTCCAACGCCGCCAAATCCGATCACGCGTCCAACGACGAAAAACCCGCCGACTTCTCCGTCAGCGCGGAGAAGCACGCGAACGCCTCGATGGCGGTCGCCGATCAGCACGAATTGAAATACAAATGTGAATATTGCggcaaaaagttcaaattccaGAGTAACCTGGTCGTGCACAGGCGTACGCATACGCGCGAAAAACCATACAAATGCACGATATGCGATCACGCGTGCACGCAGAGTTCCAAACTCAAGCGACATATGAAAGTACACAAGAATTCGGCCCGGGGAAACGGGCTGACCGGTGGCGAAGCTGGAGTCACGTCGACCAACGGAGATGGCAGTACAACTTCGACACCGGAGCAAATATCTAATGACGGATCGGACGACGAGAGAATAGACGACGACGAGGAAGCGGCCGAAGAAGAGGAAGAGGAGATGGACGACGAGGaggacgacgaagacgaagaggacgaagaagaagaagatatGGAACTGGACGAGGAAGGcgacgaggacgacgacggcgacgcgCCCGAGGATTTGACCACCAAGTCGACCTCGTCGACGCCTCCCAACAACGCCGAAGAGAACAGTAAATCGATGCAGTCGCCTAGACCAACGCCTTCTCAGACGCCGCTGGACAAGACGCCTTCGGATAAAGTTTCCTCGTCCGGATCGCTGGTCAGCGAACTAATGGATAAGTTCGGATTAAGTAGTAATCAGTTGTACAGCGAAGCGTACAAGCAGGCTCTCCAAGAGTCCAGCCATAACCCGCATATCAGAAAGAAGGACGACGCAATGCTCGAGCCGGTCGCTCCCGACAACAATAACGTCAATAAAATCCCGCCtcctattttagaaaatggcaTGAAGATGAAATCTTCGGCGGCCATCAAACTGAAAGAAGATTTCGCCGCCAATCTGATGGCTAGTCAACCTCCTCTAGATATACTAGGTGCTTCTCACGGTTTCTTCGGCGCCGGCTTGCCGTTCGAGAATCTACTCGACGTGGCTACCAGCAAACGAATGAAACTCGACATGGACGGTCGGCATAATCCTTTGCTGGGCCGCGCCAATCTGCCGCCAGACGCCGACGGCATTTACCCGGGCCTCTGGCTACCCGGCCTGGCGGCCGCCCACCAACGTGACATCTTCGGCCGCAACGACGTACCCCTCGATATGTACAAGCCGCGCTCCAAGTCAAACTCGGAGAACCATCGCCACCACGGTAACCATAAATCGCATAATTCGTCGTTGGCCGCGGCCGCGGCAGCCGCCATGAACCTCAGACTACCGAATCAGCATCTGAAGAAGGAGAGTCGACGTAACGACACGTGCGAGTACTGCggaaaagtattcaaaaactgTAGCAACCTAACGGTGCACAGACGATCTCATACCGGCGAGAAGCCCTACAAGTGCGAATTATGTTCCTACGCGTGCGCCCAAAGCTCGAAGCTCACCAGGCATATGAAAACCCACGGCCGAATGGGCAAAGACGTCTACCGCTGCAGGTTCTGCGAAATGCCCTTCTCCGTGCCGTCCACCTTGGAGAAGCACATGCGCAAATGCGTCGTCAGCCAGAATATCAAGGATAACGGAACCCTTATGCCATCCATGCTGATCAAGTGCGACGACGACTCCAGCATATCGTCGTCCAAAGATAACACTTGA
Protein Sequence
MVLFLFFLFTEPSYYICSTCKQRLHSAWRLVQHCQNSHGIKIYLESSSSTSSSPSATNCAPPPKSASNNNHSSSSSSCSRFSASSSSNCSGNSSSGAGGVPGNGGGAGNSVGSLAASSLPLPSASISSRLPLLPPTSTSMVDPRNPFGVGGLLRLPLNDPTRHHQFPTTLGGLHGGGTGANSPVFARPSSSHQDNHFRMEQIVSEQFRLNSHHSMGLAAAAAAVAASAAAGIPPPHSPYPPVDRPPSNSMHTNGPRSMIPPPPSLSLPLEPQLDFYSQRLRQLAGTTSPGVANGPNSLSPRKLTPPFTSPGNSQPLPPSRSSSTDNSANDSLDLSSNAAKSDHASNDEKPADFSVSAEKHANASMAVADQHELKYKCEYCGKKFKFQSNLVVHRRTHTREKPYKCTICDHACTQSSKLKRHMKVHKNSARGNGLTGGEAGVTSTNGDGSTTSTPEQISNDGSDDERIDDDEEAAEEEEEEMDDEEDDEDEEDEEEEDMELDEEGDEDDDGDAPEDLTTKSTSSTPPNNAEENSKSMQSPRPTPSQTPLDKTPSDKVSSSGSLVSELMDKFGLSSNQLYSEAYKQALQESSHNPHIRKKDDAMLEPVAPDNNNVNKIPPPILENGMKMKSSAAIKLKEDFAANLMASQPPLDILGASHGFFGAGLPFENLLDVATSKRMKLDMDGRHNPLLGRANLPPDADGIYPGLWLPGLAAAHQRDIFGRNDVPLDMYKPRSKSNSENHRHHGNHKSHNSSLAAAAAAAMNLRLPNQHLKKESRRNDTCEYCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRMGKDVYRCRFCEMPFSVPSTLEKHMRKCVVSQNIKDNGTLMPSMLIKCDDDSSISSSKDNT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00194706; iTF_00725818; iTF_01491354; iTF_01263892; iTF_01150738; iTF_01262902;
90% Identity
iTF_01491354;
80% Identity
-