Basic Information

Gene Symbol
-
Assembly
GCA_900080175.1
Location
FKYK01018712.1:26512-28785[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.026 2.2 9.0 3.5 2 23 8 30 7 30 0.93
2 15 9.6e-05 0.008 16.6 5.3 3 23 37 58 36 58 0.97
3 15 0.00085 0.071 13.6 5.4 2 23 125 146 124 146 0.96
4 15 7e-07 5.8e-05 23.3 0.6 2 23 154 176 153 176 0.96
5 15 0.0013 0.11 13.1 3.7 1 23 182 204 182 204 0.98
6 15 2.7e-05 0.0022 18.4 2.3 1 23 210 233 210 233 0.91
7 15 0.0036 0.3 11.7 1.3 1 19 312 330 312 335 0.94
8 15 0.044 3.7 8.2 0.2 3 23 344 365 342 365 0.95
9 15 1.6e-05 0.0013 19.1 1.2 1 23 370 392 370 392 0.96
10 15 4.2e-06 0.00035 20.9 2.5 1 23 396 418 396 418 0.97
11 15 2e-07 1.7e-05 25.0 1.6 1 23 424 446 424 446 0.97
12 15 0.05 4.2 8.1 1.3 1 23 452 475 452 475 0.93
13 15 0.00018 0.015 15.8 0.9 3 23 483 504 481 504 0.96
14 15 2.1e-05 0.0018 18.7 2.1 1 23 510 532 510 532 0.97
15 15 9.5e-07 7.9e-05 22.9 0.8 1 23 538 560 538 561 0.95

Sequence Information

Coding Sequence
ATGCCAGAATCTGAACCTTTGGTTTGTAACGATTGTCAGAAACCTTTCTGGTCGCGAAATTGTCTCAAGCAACATATTCATCTAAGACATGTGCAGGAACCATCGCTTTGCAATACCTGCaataaaacgttcaaaaataaattctgtcTTAGGATCCACATTAGAAATAATCATGacgcgattttgaaaaatatacttgcGAGATATAAAAGCTTTCGGTTAAAAGTAAATCTGAGAGAGCGTATTATTAAAATCCATACTTACAAATACAACTGCGAGAAATGTTGTAAACGTTTTCATACCGAGGTAGAATTTTATTCGCACGATAACACTCATACAGCTGACGGTAAGTTGGTTCTACCAAAGAAGTGCGTTTGTGAATTTTGTGGGAGAGCCTGTCGTACTGAATTCCACTTAGTTTCTCATCAACGTATTCACACGGAACCGCCTGAAAAGCTTCCTTGCGGAATATGCGACAAGACTTTCTCTTACAAGTTTGCATTGAAATCACATCAGAGGAGGGTccacgaagaaaagaaattattcacATGTGAAATTTGCGACTACAGGTGTAAAACATTGCAATTATTGACCGATCATTTCAACAAGCATACTGGCGAAAAACCGTATTGTTGTGAGAAGTGCGATGTTAGCTTTTCTACTAAAACTGCTTTGAAGAGGCACACAGCTGCTTATCATTCAACTACTCAGGAGAGCGAACCGCCGCCAATTGAAAGTTGTAGCAGTCCCTACTTCGAAACTATTTACGTTTTAAGTAGTCCTTGCTCAAAAGACGATGAAACCGACTCGCATGACGTAATCGCAACAAACACAACcgctaacttgaaaaaagtctcAATTAAATGTGATCCAGTCCTAGCTGAACAGTTACCAAAGAAGAAACCATTTAGTACATATTATAGACCGCAACATTTTCCATGCGGTAtttgccataaaatttttactcgagttTGCGATCTCCTAAATCACGACAATGCCGATCACCAAAACATACCTCGTGTCGTGAACTGTGACATTTGCGGTAAACTAGTCATATCAGAAGACAGACTTACGCTTCATAAACAGAAATTTCACGGTGAGAAAATCTATCCTTGCAACATTTGTCAGAAGAAGTTCGTCTCTTATAAATCACTAGAAAAGCATTACGATTTACACTTTCAATTGTTTATTTGCGATCACTGCCAGAAAAGTTTTCGATCGAAAAACACTTTGGCGACGCATATTGCCAAACATACGTTAAAAGAGACGTTTGATTGCAAGGATTGCGGTAAAAGTTTCTCTACTAAGGCTGGATTGCATATTCACGAAAGAACTCATTCTACAGTGAAGCTGTTCAAATGTGATAAATGCGGGTTCGCTGCCAAACACCAAAGTGGCATTTATATACATACGTTAAATCGACACACAACAGAAGAAGCCGTTATCTGCGAACTGTGCGgtatatctttcaaaaataagatgCGTTTAAATGAGCACCGTAAACGAAAACACGGTACGCCGAAAAGATTCGCATGCGATAAATGCGATCGTATGTTTAAAATGATGTATCAGCTAAGACTTCATTACAGAACGCATACCGGAGAGAAACCGTTTATTTGTGAGGTTTGTGGCAGAGGATTTACTCGAAGCGATGGATTAAAAGAACACAAACGTATTCATCACGAATTTATACCACTAAAGTTGTAA
Protein Sequence
MPESEPLVCNDCQKPFWSRNCLKQHIHLRHVQEPSLCNTCNKTFKNKFCLRIHIRNNHDAILKNILARYKSFRLKVNLRERIIKIHTYKYNCEKCCKRFHTEVEFYSHDNTHTADGKLVLPKKCVCEFCGRACRTEFHLVSHQRIHTEPPEKLPCGICDKTFSYKFALKSHQRRVHEEKKLFTCEICDYRCKTLQLLTDHFNKHTGEKPYCCEKCDVSFSTKTALKRHTAAYHSTTQESEPPPIESCSSPYFETIYVLSSPCSKDDETDSHDVIATNTTANLKKVSIKCDPVLAEQLPKKKPFSTYYRPQHFPCGICHKIFTRVCDLLNHDNADHQNIPRVVNCDICGKLVISEDRLTLHKQKFHGEKIYPCNICQKKFVSYKSLEKHYDLHFQLFICDHCQKSFRSKNTLATHIAKHTLKETFDCKDCGKSFSTKAGLHIHERTHSTVKLFKCDKCGFAAKHQSGIYIHTLNRHTTEEAVICELCGISFKNKMRLNEHRKRKHGTPKRFACDKCDRMFKMMYQLRLHYRTHTGEKPFICEVCGRGFTRSDGLKEHKRIHHEFIPLKL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-