Basic Information

Insect: Toxorhynchites rutilus
Gene Symbol: -
Assembly: GCA_029784135.1
Location: CM056649.1:37740322-37746250[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 8.1 9.2e+02 2.3 0.2 2 16 170 184 169 186 0.90

2 18 2.6 2.9e+02 3.8 1.7 2 23 262 284 262 284 0.91

3 18 0.12 14 8.0 2.2 1 21 293 313 293 314 0.96

4 18 1.5 1.7e+02 4.6 2.9 1 23 358 383 358 383 0.89

5 18 0.022 2.6 10.3 0.7 2 19 393 410 393 412 0.94

6 18 0.00025 0.029 16.5 2.2 1 21 514 534 514 535 0.95

7 18 0.0051 0.58 12.3 1.7 2 23 586 608 585 608 0.94

8 18 0.00052 0.059 15.5 0.0 2 21 618 637 618 638 0.94

9 18 7.2 8.2e+02 2.4 2.5 1 20 645 667 645 672 0.93

10 18 0.35 40 6.6 0.1 3 22 733 752 732 752 0.97

11 18 5.3 6e+02 2.8 1.1 2 23 786 810 785 810 0.88

12 18 0.34 39 6.6 0.2 3 21 829 847 828 848 0.96

13 18 0.9 1e+02 5.3 0.2 2 16 853 866 852 871 0.73

14 18 9.4e-06 0.0011 20.9 0.2 2 23 914 935 913 935 0.96

15 18 0.043 4.9 9.4 0.5 1 23 941 963 941 963 0.96

16 18 1.4 1.6e+02 4.7 3.2 1 23 969 993 969 993 0.95

17 18 0.00042 0.048 15.7 0.6 3 23 1001 1021 999 1021 0.98

18 18 0.035 4 9.7 0.1 1 20 1027 1046 1027 1048 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	8.1	9.2e+02	2.3	0.2	2	16	170	184	169	186	0.90
2	18	2.6	2.9e+02	3.8	1.7	2	23	262	284	262	284	0.91
3	18	0.12	14	8.0	2.2	1	21	293	313	293	314	0.96
4	18	1.5	1.7e+02	4.6	2.9	1	23	358	383	358	383	0.89
5	18	0.022	2.6	10.3	0.7	2	19	393	410	393	412	0.94
6	18	0.00025	0.029	16.5	2.2	1	21	514	534	514	535	0.95
7	18	0.0051	0.58	12.3	1.7	2	23	586	608	585	608	0.94
8	18	0.00052	0.059	15.5	0.0	2	21	618	637	618	638	0.94
9	18	7.2	8.2e+02	2.4	2.5	1	20	645	667	645	672	0.93
10	18	0.35	40	6.6	0.1	3	22	733	752	732	752	0.97
11	18	5.3	6e+02	2.8	1.1	2	23	786	810	785	810	0.88
12	18	0.34	39	6.6	0.2	3	21	829	847	828	848	0.96
13	18	0.9	1e+02	5.3	0.2	2	16	853	866	852	871	0.73
14	18	9.4e-06	0.0011	20.9	0.2	2	23	914	935	913	935	0.96
15	18	0.043	4.9	9.4	0.5	1	23	941	963	941	963	0.96
16	18	1.4	1.6e+02	4.7	3.2	1	23	969	993	969	993	0.95
17	18	0.00042	0.048	15.7	0.6	3	23	1001	1021	999	1021	0.98
18	18	0.035	4	9.7	0.1	1	20	1027	1046	1027	1048	0.94

Sequence Information

Coding Sequence: ATGCTAGAAATTGTGGGTGGAATAAAgTTAAATGATAGCGATCGTTTACCTGATCAAATATGCGATCAATGTTCGAAGATCCTCGATGATGGATATTCATTGTGGAAACGCTGTCGTGTCCATCATCTCATAAGCAAATGCATTGAAGGACAGGAAGATCAATACCTACGCTGCCGAATCTGCACCCAACAGGATGTGAGCGAATTAATTTCCCTTCATAGCGTGTGTGACACATGGAAAATGAAAGTCCATGAAATGGTTCGATACATAAGCGGTGTGGCCATTAACAAGAAAGCCATTGGGCTGCCGCCGTATGTTTGCGATGTCTGTCTAGATGTACTGGATAAGAGTGTGAGATTCAAAAAGCTTTGCCTTGAGACGAATGAAATTTTGCGCAGTGAAACTTCGTACGCTTGGGAGAAGATGGCATTCGAAACCAGCGATCGGGATAGCTTGGTAGTCGATCTGTTTGCAGAAATAGTCCACAATGTTGATACGGGAAAACTTAAGTGTTCGATATGCAAAAATGATGTAACTTCAAGTTCGCAACTTAGTAGTTGCGACGGGTGtttattgaaatttcaaaatataactgaaataaacaatattGAAAATGAGAAAGACAACATAATTCAAACGGAAGACGACGTAATTGAAACGGAAGGCAATGTCATTGAAACAGAAGACAACGAAGCAAACATAGATTCAAAGACGGCTCAATTTTTCGATCTTCTTGAGGATGCCTCTGATGGATTATTTCTCAAGATTCGACGCAAAGGTCCAGTCTGCTGCGGCTGCAACAAAATATTCTTATCGGAAAATGATTTACATGAACACAGATTGGAAGTGCATCCACCAATTGACGTTAAAAATCAGTATTATTGTGAATTTTGCCGACGTAATCTGGAATCTAAAACGCAGTTGGAGAATCACCACAGAAATATGAGGAGCGACATATTTATGTATTGCAAAATATGTCGAAAAATACAAACTGATCCAAAACGACATAAAAAACTATCTCATATTTCGGAGGAAACCTTAAAGAAGTTTAGAAAGCAAATCACCACGATCTACGAATGTTGTATTACGCATTGCGACTCGACCTACGACACCCAGAATCTGTTATTGAAGCATTTCGCTGAAACACATTCTAGAAACGATTTAGCAGAGAGCAATACCTGTGGATATTGTGACAGAAAGTTTTCCAGTAAGAACGCATTCCTAGAGCATAATACCCATGCAGTAATGAAGGAGAAATTTTTCTGCCAGATAGATGAATGCACCTACACAGATAATGACTTGCACGGTATTATTATGCATTGCTCCGATCAGCCTCACAACGCTATGCTCACTAGTACAAACAAACGTGTCAAACCAACACCCAATATGGAAAATTTGACCACGATTGGAGATATTGATGGCATAATTGATATTTTGGACAGTAAGGGCAATTTCTGCTGTGGTTgccttcatttttttaaaaccacTCCAGAATTCGTAGCACACTGCGAAGCAAACCATAGCACTGCTACAGGTGAATTTAGCTGTAAGACGTGTAAAAAAGCGTTTTCAACTAAAAATACGTTGCGTATGCATGAAAGAAAAGGagcagaaaatatgttttactaTTGCCGCCCATGTAAACTTTTCTTTTGGGATATTCTTGAAATGAATCGCCATAAAGCCTTCGTACACACAGATATTGAACCAGAAACGATGGATGATCGTTACGAACGGGTAGCGGAAAGCGCGTTAATATGCTGTGGTTGTGATAAGCATTTTAAGTACGAAGCGGAACTCATCGAGCATCGGCTAATTAAACATTCGAGGTTCATCACGAAATTTGCCAGACAGTGTCCCGTCTGTGTTAAAATTTTCGAGTCCCCAGAACTCCTGCAGCGACACATGGATATGGCCGATAGCAACATGGTTTATAAGTGCAAGGCAGCAGAGGATTGCACTTTCCGATGCAAGCAACTGTCCACCATCAAACTTCACGTTACATTCAAGTCACATCAAACTGTAAAAGGCTACGTATATCTTCGCGATGTGAAGATAACCCAGCACGGATGCTGCTTTATACATTGTGACTTTGTTGCTGACAGCTACGATGAAATCGTGACACACGCTAACACTAACCACAACGTAGAACGCGAGAAGAACAGGGCACTTCCAGATTgccttgaaaaaatattgtGCCCCGTTTGCTATAAAATAATGGGAAGTAAGATATCACTAATGCGGCATCAGCGGACTGGTTTGGATATAACTTGCAGATTTtgcatgaaaacattcaaacgAGAAGAGTATTTCACGCATGCTGAGGCGTGTCGGATAAAAACCCCGAAGCAACACATTTGCTGCATTTTACATTGTGACTTCGTTGCTGATACTTACGATGAACTCATCAAACATGCTGACATTGATCACGTAGCAGTGCGtgaaaaaaatacgatacttcCCAATCGTTATGAAACAATGTTGTGTCCCGTTTGCCATAAAGGAAAGCCAGATGAATATTCCCTGTTTCGTCATCAGCGTGCAAGACGGTTCACTCGCTGTAAAATTTGCggtaaaaaaattaaacgagAAGAGTATTCCGCTCATATTGAAGGATGTCAGACAACATCGAAAGCTAAGTGTGGGGAATGTACTTCAGATTCACCGTGTTCGATTCATTCCAAAACTCATAGAAAAACGAAGTATGAAAAACGACAACTTGTTAGTGGCGGTTCTACAGTTTGTAGTATTTGTGGTAAATTCTACAAAACTCAAGCCATGTTGCGTGACCACATGATAATTCACCAGAATAAACGAATCTACAGGTGTAATTTGTGTCCCCTCACTTTCAATAGCTATCTCATTCTAAAGAATCACGGTCGTGTCCATACGAAggagaaaaaatttaaatgccGCCAAGGCTGCGAAAAAATGTTCAAGTGCCCTAGTGATCGATCTCGTCACGAGAAGAGTGTACATTTAGGTATTAAACCATTTGGCTGCACCATCTGTTCGGCCTCATTTGTACGCGATCGCGATCTTCGACTGCATATGCGGAAACACACGGGACTAAAGCTCTTCCCTTGTGATAATTGTGGTGCAAGTTTCGACGTGATGAGTGAATTCAAGCAACACAAAGGAAAATGTGTGACCACTAAAGGGTCACAATCGATCGTAGTCGAGAATGCCAGTGAATAA
Protein Sequence: MLEIVGGIKLNDSDRLPDQICDQCSKILDDGYSLWKRCRVHHLISKCIEGQEDQYLRCRICTQQDVSELISLHSVCDTWKMKVHEMVRYISGVAINKKAIGLPPYVCDVCLDVLDKSVRFKKLCLETNEILRSETSYAWEKMAFETSDRDSLVVDLFAEIVHNVDTGKLKCSICKNDVTSSSQLSSCDGCLLKFQNITEINNIENEKDNIIQTEDDVIETEGNVIETEDNEANIDSKTAQFFDLLEDASDGLFLKIRRKGPVCCGCNKIFLSENDLHEHRLEVHPPIDVKNQYYCEFCRRNLESKTQLENHHRNMRSDIFMYCKICRKIQTDPKRHKKLSHISEETLKKFRKQITTIYECCITHCDSTYDTQNLLLKHFAETHSRNDLAESNTCGYCDRKFSSKNAFLEHNTHAVMKEKFFCQIDECTYTDNDLHGIIMHCSDQPHNAMLTSTNKRVKPTPNMENLTTIGDIDGIIDILDSKGNFCCGCLHFFKTTPEFVAHCEANHSTATGEFSCKTCKKAFSTKNTLRMHERKGAENMFYYCRPCKLFFWDILEMNRHKAFVHTDIEPETMDDRYERVAESALICCGCDKHFKYEAELIEHRLIKHSRFITKFARQCPVCVKIFESPELLQRHMDMADSNMVYKCKAAEDCTFRCKQLSTIKLHVTFKSHQTVKGYVYLRDVKITQHGCCFIHCDFVADSYDEIVTHANTNHNVEREKNRALPDCLEKILCPVCYKIMGSKISLMRHQRTGLDITCRFCMKTFKREEYFTHAEACRIKTPKQHICCILHCDFVADTYDELIKHADIDHVAVREKNTILPNRYETMLCPVCHKGKPDEYSLFRHQRARRFTRCKICGKKIKREEYSAHIEGCQTTSKAKCGECTSDSPCSIHSKTHRKTKYEKRQLVSGGSTVCSICGKFYKTQAMLRDHMIIHQNKRIYRCNLCPLTFNSYLILKNHGRVHTKEKKFKCRQGCEKMFKCPSDRSRHEKSVHLGIKPFGCTICSASFVRDRDLRLHMRKHTGLKLFPCDNCGASFDVMSEFKQHKGKCVTTKGSQSIVVENASE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -