Basic Information

Insect: Toxorhynchites rutilus
Gene Symbol: -
Assembly: GCA_029784135.1
Location: CM056647.1:28287562-28289966[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 6.6 7.5e+02 2.5 2.3 1 23 370 395 370 395 0.78

2 8 0.02 2.2 10.5 0.7 2 23 400 422 399 422 0.95

3 8 0.00012 0.013 17.5 1.2 3 23 433 453 431 453 0.96

4 8 0.0036 0.41 12.8 3.6 2 23 458 479 457 479 0.97

5 8 0.11 13 8.1 0.3 1 23 485 507 485 507 0.98

6 8 2e-05 0.0023 19.9 4.7 1 23 513 535 513 535 0.99

7 8 0.00025 0.029 16.4 4.5 1 23 588 610 588 610 0.98

8 8 3.1e-06 0.00035 22.5 1.7 2 23 617 639 617 639 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	6.6	7.5e+02	2.5	2.3	1	23	370	395	370	395	0.78
2	8	0.02	2.2	10.5	0.7	2	23	400	422	399	422	0.95
3	8	0.00012	0.013	17.5	1.2	3	23	433	453	431	453	0.96
4	8	0.0036	0.41	12.8	3.6	2	23	458	479	457	479	0.97
5	8	0.11	13	8.1	0.3	1	23	485	507	485	507	0.98
6	8	2e-05	0.0023	19.9	4.7	1	23	513	535	513	535	0.99
7	8	0.00025	0.029	16.4	4.5	1	23	588	610	588	610	0.98
8	8	3.1e-06	0.00035	22.5	1.7	2	23	617	639	617	639	0.95

Sequence Information

Coding Sequence: ATGGGCCATCGGAAGATTCGAATGTGCCGACTTTGCCTGTCCACGACAGCGGTACTAAGATCTATATTCACCATATTTCGGAACCACAACCTGGTGTTCATTATTCGGGATTACGTGAAACTAGAGGTGAAGGAAGACGACGGGCTACCGAAACTGGTGTGCAAGTCGTGTGCGGTCAAGTTGATACGGGTGCGGGAGAATGTCACACTGTTTCTCGATAGCGATCGGAAACTACGAGACAAATTGAAGTATGGATCCAGTTTGGATGTAGATAATGACATGGATGAGGAGGAATTAGACGAGAGCAATAATTATGAGCGGGTTAAACAAGAAATTCATGACCCTGAGCTTCCAACCGGTAGATTAGCATCAAGGGATGGACCAAATGGTGATCGGGAGCAAAATTTGTTTGAATTCAACGAGGTTAAAGAAGAAACTTTCGACAGTGACGCAGAGGAGGATTTACCGCTACTGGTGCTAAAGAACATCGCTAGCAATGGCGAAGTAGCACGGGCGCCGGTTTGTTCGACGAATAGCACAATTAGTTTAGAAAGCGAAAcgaaagcgtttgaaattgaatcCGAGAAATGTAAACCAGAATCAGTGAACGACAAGGTTGAAACTTTGAGCAGTGATAAACTATCCGACTGTGATGAGAACAAAAAAATGTGTCAACTTCCTTCTGATACTGATAGCTTTGACGAGATGTCGTTGgcaaagaaaagaaaattagCACGAATGAAAAGGAGAGAGGAGACTGTTGAACAGAAACTAGAGGGTTCAAACCGGAGGCGGACACGTGCATTTAGGGTTGAGGAAGACTCGAAAAATGAGGCTTCTGGTGATGATGAGGAAGATCGGTTTGAACAAAATAATTTCGACTCAAACTGTTCACAAGATGAGTTCGTATTCCAAAAAGACAAtgagaggaaaagaagaagtacGAAAGTACAAAAACGAAAACGTGGTCCCAGGAAAAAACttatggaaaaaatgaaatcaacTCCTACATTACACGACTACAGATGCTATATATGCAATAGTGATTCGTTGGGATCCAGAAAAGCAATGATTGAACACTTTTCGGTACACGTAGATAAAGTTCCCTACACATGCCGGGAATGTGTCATGGAAACGGTGGTTTTAACGAGGGTTCGAACGTTGAACACGCACATGAAGATGCATGCTCAACCAGTCAAGTGTGACTATTGCGATCGCCGATATAGCAATGCGGCGGGGAAGTATTATCACACGCAAACATTCCATCTGGGTGGTGGGGCTCCCTGTCTTGTGAACTGTGAGGTGTGTGGCAAGACATGTGGTTCCCAAATGGCGCTCAAACAGCATATGAAATATCATACGACCAAGCTTAAATGCAGTAAATGTGACATGGTTTTCAACCACCCGAACAAACGACGGAATCATGAGCGGACGCACGATGAAAATCGCGGATACGAATGTGTGGTGTGTAAAAAGGTTCTTCAGACAATCGAGTCCTATGACGTGCACTTGAAAAAGCACAGCCAAGAGCGCAGCTACCAATGTCATCTATGTCCGAAAAAGTTCAACACATCGTGTAACTTGATACTGCATCTGAAGGTCCATGCAAAAAATGACAACTATAAGCCGGCGAAATCGTGGATTGAGCACTACACCGTGCTTAGTCGAAATCCGATGCACTTCAAGTGCAAACACTGCGATCGCTACAACACCGACAAGGTGAACAATATGATATCACACCTGCAAGCCCATTTCAAGGAATACGAGTGCGACCAGTGTCACCATAAATTTGCAACCGCCAAGCAGCTCAGAGCACATTACACCACCCACACTGGGGAAAAGCCGGAAAAGTGTAAATACTGCGAGAAGGTTTTCTCAACGAAGAACAATTTGAGAATCCATCTGAAGGCAACCCATCCGGAATGGGCACCTCgaagacaacaacaacaaactccAACACAGCATGATGACGTGATTATACCCGGTTCAGTGCAAAGTTCAACGGCAGCTGGATCTCCACCGCAGCCAATAAACACTCCGAATGACGAAAGCTTCGAGAGCTCTACCGTCGGCAGTACGTATGGGATTATGCGGGATGCCCAAGTAACCGTTTTGCAACAGCCGCCGGCAGAACATCAGTTACACACGCTCGGTGTACTTAGGAGCTAA
Protein Sequence: MGHRKIRMCRLCLSTTAVLRSIFTIFRNHNLVFIIRDYVKLEVKEDDGLPKLVCKSCAVKLIRVRENVTLFLDSDRKLRDKLKYGSSLDVDNDMDEEELDESNNYERVKQEIHDPELPTGRLASRDGPNGDREQNLFEFNEVKEETFDSDAEEDLPLLVLKNIASNGEVARAPVCSTNSTISLESETKAFEIESEKCKPESVNDKVETLSSDKLSDCDENKKMCQLPSDTDSFDEMSLAKKRKLARMKRREETVEQKLEGSNRRRTRAFRVEEDSKNEASGDDEEDRFEQNNFDSNCSQDEFVFQKDNERKRRSTKVQKRKRGPRKKLMEKMKSTPTLHDYRCYICNSDSLGSRKAMIEHFSVHVDKVPYTCRECVMETVVLTRVRTLNTHMKMHAQPVKCDYCDRRYSNAAGKYYHTQTFHLGGGAPCLVNCEVCGKTCGSQMALKQHMKYHTTKLKCSKCDMVFNHPNKRRNHERTHDENRGYECVVCKKVLQTIESYDVHLKKHSQERSYQCHLCPKKFNTSCNLILHLKVHAKNDNYKPAKSWIEHYTVLSRNPMHFKCKHCDRYNTDKVNNMISHLQAHFKEYECDQCHHKFATAKQLRAHYTTHTGEKPEKCKYCEKVFSTKNNLRIHLKATHPEWAPRRQQQQTPTQHDDVIIPGSVQSSTAAGSPPQPINTPNDESFESSTVGSTYGIMRDAQVTVLQQPPAEHQLHTLGVLRS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -