Trut034490.1
Basic Information
- Insect
- Toxorhynchites rutilus
- Gene Symbol
- -
- Assembly
- GCA_029784135.1
- Location
- CM056649.1:37607441-37609759[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.0003 0.034 16.2 0.6 2 20 314 332 313 334 0.94 2 11 0.44 51 6.2 0.3 1 19 341 359 341 361 0.94 3 11 0.03 3.4 9.9 0.1 2 23 392 414 391 414 0.94 4 11 0.025 2.8 10.2 0.1 1 20 424 443 424 445 0.95 5 11 0.00094 0.11 14.6 1.3 2 23 538 559 537 559 0.97 6 11 2.1e-05 0.0024 19.9 0.8 1 23 564 586 564 586 0.97 7 11 0.0055 0.63 12.2 0.3 1 23 593 616 593 616 0.96 8 11 0.0033 0.37 12.9 0.5 3 23 624 645 623 645 0.91 9 11 3.8e-05 0.0044 19.0 0.6 1 23 651 673 651 673 0.99 10 11 0.58 66 5.9 6.5 1 23 679 702 679 702 0.97 11 11 0.00024 0.027 16.5 0.4 1 23 708 730 708 730 0.98
Sequence Information
- Coding Sequence
- ATGTTCGCGAACCATGGATTTAATTTAAACAATTGTTCCATCACAGGGTACGGGGCGAATGAATCTGAGATGGAGGAGGACCTTTGCTGCAGGCTTTGCTTGGAGACGGAGGTGGATGAATTAATATCCTTGTACTGTAGGTGCGACTCACAGAATCAATTGGTGTCGGAGATGGTCACCGATTTGATAAGGCTGGGTTCTCCTCGGGAAAACGATCGCTTGCCCCAGTTTGTGTGCGGAGGATGTCTCGAGCGTTTGGATAAAGCTTGCACCTTCCGCAAGTTATGCATCAACACCAATCGCCATTTGCGAAGGAAATTGCTGCAGAGGGAATCAGCTGCCGACAACGACGAACATTGTCGCATTTGCAACGTAAATGATTTAGATGAACTGATTTCTGTGTTCTGTATTTGTGCTGGGGAAGAAGAGAAACTCGTTGCGGATATGATGATGGAAATCACCGGCACAATACGTCCGTCGAGCGAAGATGGATTATCGCAGAATATTTGCGCGAAATGCTTCGAACAGCTGTCGGAAACTGTTGCTTTCATAGCTATGATATGCAATTCGGACGTGAAGCTGCGTAAAAGCCTAGCTTCACAAGGAGTTACTGAGAAATGCCTGATAACGAATAGAGATAATCAAGAAGATGAAGATTCCAGAGCGATTCCAGAGCGAAAGAAAAGGAAAACGATATCACAGAGGGATACTTCTCGGAAAGTAGATGAAGCGGATCCCTTCATTTACCTCGATGCACATGACGTTGATGCGGAGCAGCTGAGATCCTTGTTTGTTTCCATCGACGACGCTGAGTTTGACGAGCGACTGAGATACTTTGGAACTATTTGTTGCTGCGGAAAGTTATTGGAGGACGAAGAGAAATGGAAAGAGCACATCAAAGTTGATCATACGGCGAGAGAAAAAGCGTGGAGTAACATCAAGTGTAACGATTGTAACAAACGTTTTCAATACAGCAGTGGACTGACGCAGCATAGGGAAAACCGAGAGAGAAAGGAATACTACCGATGCAAAATATGCAACATTTTGACTAAAGAGAGACGTTCGCTGCAATTGCATTTCGAGTTCACCCGGTTTCATCCTATTCTCGAGACATCAGAAGAAGAACGATTgagatttgatgaaaaaattatgacAATTGAAGAACCGGACACTCGATGTTGTGGCTGTGACGAAGTTTTTCCCGACGGGGCATCGTTAGTCGAACACACCAAAGAAGTTCACTTCAAGGAAAATGACGGGATTCCCTCGTTTATGTGTATGATTTGCTACGGCAGCTTTTCCGAGAAACGAATGTTAACGCGTCATCAAATAGCTTATGCTGGAAGAAGATATTATGTTTGCCTCGAAGAAGGATGCCAATTTAGAAGCGACGAACGTTTAATCATCAAAAAACACGTGGATTCGGGTTTGCACTGTAACACAAGTATGCTCCCAGAACCCGAGCCGGAACCGGAAATAACGGAGTTTTTCTGCTGCTTCCAGATGTGTTATGAAACTTTCGGCACTATGGAGGAGCTCGAAAATCATTGTTACGTGCATCACGGCGAGCAACGTGCTTTCAACAGTCATTTCAGCAAAGATTCCGAAAGTGTTTGTCCGTTGTGCAAACGGCACTTCGCCAAGAGAAGCGTTTTTCAGGCCCACATTCAGTCACATACAAATAGAAAATTCGCTTGTGCCACATGTGGCACGAAGTTCGCAACACGCGATACTTTAAAGAAACACGAGAGGAGTCATTCGCGTATAAGCAATGCATATTTCTGTCAACAATGTACTGCAGTTTACGCCACCCAGCAGGCTCTCAGCCGACATGTGCTTAAGGTTCACGAGAAAATTTTCACCGAACTCTGCAACATCTGTGGTAAAGGATTCGTTGCCAAACATGAGCTGAAGTTGCACGAAGCGAACAATCACATGAAAGAACGCCCTTTCAAATGTACGGAATGTCCCATGACGTTCGGGATAAAACAACTGCTGCAAAAACATATGATAACCCATAGCACGGAACGGCCGTACAAATGTTCCTTCTGTTCCAATACCTATCGGCATCCCAGCGACTGTAAGCGACACGAAAAGTCAGTTCACCTGAACGAGAAGCCTTTCCAATGTGAAGTTTGCGAAGCTAGCTTTATCCGAGATCGGGACTTGCGCCTACATATGACCAAGCACACCAAGGTTAAGCTGTACTGTTGTCCGGTAGCGGATTGTGCGTTTTCTACGAATGTGTCCAAAAAGGTGAACATACATTACAATGAAAAGCACACGAAAGAGGAGGAGGAGCAATCGGATTACAACTGA
- Protein Sequence
- MFANHGFNLNNCSITGYGANESEMEEDLCCRLCLETEVDELISLYCRCDSQNQLVSEMVTDLIRLGSPRENDRLPQFVCGGCLERLDKACTFRKLCINTNRHLRRKLLQRESAADNDEHCRICNVNDLDELISVFCICAGEEEKLVADMMMEITGTIRPSSEDGLSQNICAKCFEQLSETVAFIAMICNSDVKLRKSLASQGVTEKCLITNRDNQEDEDSRAIPERKKRKTISQRDTSRKVDEADPFIYLDAHDVDAEQLRSLFVSIDDAEFDERLRYFGTICCCGKLLEDEEKWKEHIKVDHTAREKAWSNIKCNDCNKRFQYSSGLTQHRENRERKEYYRCKICNILTKERRSLQLHFEFTRFHPILETSEEERLRFDEKIMTIEEPDTRCCGCDEVFPDGASLVEHTKEVHFKENDGIPSFMCMICYGSFSEKRMLTRHQIAYAGRRYYVCLEEGCQFRSDERLIIKKHVDSGLHCNTSMLPEPEPEPEITEFFCCFQMCYETFGTMEELENHCYVHHGEQRAFNSHFSKDSESVCPLCKRHFAKRSVFQAHIQSHTNRKFACATCGTKFATRDTLKKHERSHSRISNAYFCQQCTAVYATQQALSRHVLKVHEKIFTELCNICGKGFVAKHELKLHEANNHMKERPFKCTECPMTFGIKQLLQKHMITHSTERPYKCSFCSNTYRHPSDCKRHEKSVHLNEKPFQCEVCEASFIRDRDLRLHMTKHTKVKLYCCPVADCAFSTNVSKKVNIHYNEKHTKEEEEQSDYN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -