Basic Information

Insect: Toxorhynchites rutilus
Gene Symbol: -
Assembly: GCA_029784135.1
Location: CM056649.1:13467493-13488221[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.024 2.8 10.2 0.2 2 20 454 472 453 475 0.92

2 11 0.09 10 8.4 0.1 2 23 514 536 513 536 0.93

3 11 7.7 8.8e+02 2.3 2.0 1 21 544 564 544 566 0.78

4 11 8.4e-06 0.00095 21.1 1.4 1 23 574 596 574 596 0.99

5 11 5.1e-06 0.00059 21.8 4.4 1 23 602 624 602 624 0.99

6 11 0.00012 0.013 17.5 0.8 1 23 630 653 630 653 0.94

7 11 1.2 1.4e+02 4.9 1.5 2 23 669 692 668 692 0.91

8 11 0.013 1.5 11.0 5.8 1 23 696 718 696 718 0.93

9 11 0.0018 0.21 13.7 5.7 1 23 724 746 724 746 0.97

10 11 5e-06 0.00057 21.8 0.5 1 23 752 774 752 774 0.98

11 11 0.00049 0.056 15.5 3.0 1 23 780 802 780 802 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.024	2.8	10.2	0.2	2	20	454	472	453	475	0.92
2	11	0.09	10	8.4	0.1	2	23	514	536	513	536	0.93
3	11	7.7	8.8e+02	2.3	2.0	1	21	544	564	544	566	0.78
4	11	8.4e-06	0.00095	21.1	1.4	1	23	574	596	574	596	0.99
5	11	5.1e-06	0.00059	21.8	4.4	1	23	602	624	602	624	0.99
6	11	0.00012	0.013	17.5	0.8	1	23	630	653	630	653	0.94
7	11	1.2	1.4e+02	4.9	1.5	2	23	669	692	668	692	0.91
8	11	0.013	1.5	11.0	5.8	1	23	696	718	696	718	0.93
9	11	0.0018	0.21	13.7	5.7	1	23	724	746	724	746	0.97
10	11	5e-06	0.00057	21.8	0.5	1	23	752	774	752	774	0.98
11	11	0.00049	0.056	15.5	3.0	1	23	780	802	780	802	0.99

Sequence Information

Coding Sequence: ATGTTCCGAATATTTGCAGCTATTTGTACTCCAATTGCTGATCAAGTTCCTCCGTTTCAAAAGCCATATCGCTGTGCAGTTGAGGGGTGCTATAACAACAGATGGCGCACAAGAGAAAGGTTGGATTTGACTTACCACCACTTCCCGAAGGATGGAGATCGTCTCCGCGAATGGGTCAATTACTGCCGCCGGGATGACGGCTGGGAGCGCAACCAAAACGATGGGATTTGTTCGATACACTTCGATCCATCATGTTACGAAGAAAGTGATAAAATTCGAAAGGTGTTACGACCTCTGGCTGTTCCTGGCGTCGCGTATGAGCTTAGCAGTGATCCTCATTGGTTTGCACCTAAAGATTCTATGATCCCCCGTCAAAAAGCCGATGACCAAAATAACAGCGTGCAGTATATGAACGAGGAATGCCTCGAGGAGGACATGATCGTAGAAAGGCTAGACGAAgcatttgatgaaactgttacgGAGCTGAAAATCGAACCTAGATCTCCCTCTTCTGTCCCTGAAGACACAGATGATGTTAAAAAAGAAATCGAGGAGGAAGCAGTGGAACTCCCGCTGCCGCAAATCGAGGTACTAGCCGACTCACTGGACATTCCATCCGAAGATCAACTGCTCAATCAGTTTTGCCGCTTGTGCCTTCGGGAGATCCCCAATCTGTTCCCACTTATGTCCCGCATTCAGAATGTGCTCGTTCCGGAGATGTACAAGGCCGTCACCGGACTTGAGCTAGGTTTCGCAGCCAAGCTGTCGAAGAAAGTATGCATAAACTGTCTGATAAGACTCGATTATGCGTACAATATAAGGAAAGAATTTTTGGAGGCTAACCGCACCCTGAAATGCTTCTCGCTGTCGAGGATAATTTCGCTGGTGGAGAATTTGCAAAACTATCAGAAGGCCATTCGGGTCACAACTGAATCTTACGGCGAGAAGGTGCTCCGTCAGCATCGGGATATCATTCGGATGCGTCTGATCAAGAAGCAGGAGCACTTGGAGAAAATGGTGGGGGACGAAGGTATTGAAGTGTTGAAGAACAATACGCTGGTTGGAAAGTATACGAGTCGATCAGCTCGGGATCAGCCTGATTTGCCCAGTGATGTGGAAGTGGCTTCCGAAGCAGATTCACGCTTGGAACAATCCGTTGAGCTAGTGGAGATATTAGACGAGGAAAGTTTGGAAGATAGGACCGCGGAAGACATCACATTTGAGCACATCATTGATGGGGCTTACGTAGAAGAACAGGAATCTACACCACAGCATCCTATACAGTATGTAACAAAAAGAAATAGTCGGAAAGGCAATCGCTATCATATAGAACTGAGAGAAACGAAACCTGATCCGAACAAATGTTACatttgtgaaaaagtgttcgAGAACACCGAAGCACTGGAGTTGCATAAGCCGTCTCACGTTGGCATGATTCCTTACACATGCGAACGATGCGTCGAAGAAGGTGGAAGGGAGAAAGAGATCACTTCACTCATCTTGCTCCATCGGCACTTCCGGATGCACGCTGGATCGATCAAGTGTCCGAAATGTCCTATGCGCACATTCACTTCCACTGCGCTGTACGGACATATTGCATCATACCACAGGGCCGACTCGACAACGAAATACACGTGCGAAATTTGTGGCCATCAGATGGTGAACATCAAGCGGTTTCATATACACATGGGATTTCACCGAGCGGTTGAGCAAGGACGATACAAGTGCAATCAGTGCGATAAAAAGTTCGGCACGAAGGCACGGCTGGAACGCCACGAACGGATCCACACCCAGGTGAGACCGTACAGATGCAAATACTGCGACAAGTCCTTCACGAACGAAACCACGCTTCACATCCACGAGCGCACCCACACCGGCGAAAAGGGTTTCCGGTGCGACATATGTGGAGAGTGTTTTCAAAGCACGAAGAACCTCATCTACCACATTGAGGAGGCCCATGACGGTCCCAGTGGGGAACAAGGCTCGGCTGAATGCTACGAGATCAAGTGCGCAGTGAAAGGCTGCAATTATAGAACCAAAAATAGGTACAAGTATTATAACCACAAGGCAAGACACGCGCTGAGATTCCACTGCTCGTATTGCACGAAGCAGTTCGGCACCAAACAACAACTCCAGCATCATGAGACTGGTCACACCGGTGTCAAACCCTATTGCTGCGAGCAATGCGGGAAAGGTTTTCGCTATCGGcACTGTCTAATTGATCACGTGAATGTTCACAATAACATTCGGCCGTATTCGTGCGAGATATGTGGGCTGAGCTTCGTCCGTGAAAGAAATTTGAGGGAACATCGTTTGAAACATTCGGATAAATTGTCATACAAGTGTCGTTTCTGTGGCAAAAAGTTTAAGTATCGTGCGGATCAGTCAAGACATGAACGGATCCACAGAGAAACACCGGCTGACCAACCAGACATCGGAAACATCGACGAACAGGATGCGATGATGACTGTGATGGAGATTGATATGGGAGCAGATGAGTAA
Protein Sequence: MFRIFAAICTPIADQVPPFQKPYRCAVEGCYNNRWRTRERLDLTYHHFPKDGDRLREWVNYCRRDDGWERNQNDGICSIHFDPSCYEESDKIRKVLRPLAVPGVAYELSSDPHWFAPKDSMIPRQKADDQNNSVQYMNEECLEEDMIVERLDEAFDETVTELKIEPRSPSSVPEDTDDVKKEIEEEAVELPLPQIEVLADSLDIPSEDQLLNQFCRLCLREIPNLFPLMSRIQNVLVPEMYKAVTGLELGFAAKLSKKVCINCLIRLDYAYNIRKEFLEANRTLKCFSLSRIISLVENLQNYQKAIRVTTESYGEKVLRQHRDIIRMRLIKKQEHLEKMVGDEGIEVLKNNTLVGKYTSRSARDQPDLPSDVEVASEADSRLEQSVELVEILDEESLEDRTAEDITFEHIIDGAYVEEQESTPQHPIQYVTKRNSRKGNRYHIELRETKPDPNKCYICEKVFENTEALELHKPSHVGMIPYTCERCVEEGGREKEITSLILLHRHFRMHAGSIKCPKCPMRTFTSTALYGHIASYHRADSTTKYTCEICGHQMVNIKRFHIHMGFHRAVEQGRYKCNQCDKKFGTKARLERHERIHTQVRPYRCKYCDKSFTNETTLHIHERTHTGEKGFRCDICGECFQSTKNLIYHIEEAHDGPSGEQGSAECYEIKCAVKGCNYRTKNRYKYYNHKARHALRFHCSYCTKQFGTKQQLQHHETGHTGVKPYCCEQCGKGFRYRHCLIDHVNVHNNIRPYSCEICGLSFVRERNLREHRLKHSDKLSYKCRFCGKKFKYRADQSRHERIHRETPADQPDIGNIDEQDAMMTVMEIDMGADE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01471492;
90% Identity: iTF_01471492;
80% Identity: iTF_01471492;