Basic Information

Insect: Toxorhynchites rutilus
Gene Symbol: -
Assembly: GCA_029784135.1
Location: CM056649.1:38642486-38644177[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.001 0.12 14.5 2.6 1 21 162 182 162 183 0.96

2 12 0.087 10 8.4 2.2 1 23 201 224 201 224 0.90

3 12 0.00051 0.058 15.5 1.3 1 21 236 256 236 257 0.95

4 12 0.0057 0.65 12.2 2.5 2 23 274 296 273 296 0.96

5 12 0.031 3.5 9.9 1.4 1 22 310 331 310 333 0.90

6 12 0.0005 0.057 15.5 2.2 1 23 338 361 338 361 0.98

7 12 2e-06 0.00023 23.0 4.3 1 23 372 394 372 395 0.96

8 12 0.012 1.4 11.2 1.7 1 23 400 422 400 422 0.97

9 12 6.4e-05 0.0073 18.3 1.4 1 23 433 455 433 455 0.99

10 12 0.0042 0.48 12.6 5.6 1 23 461 483 461 483 0.99

11 12 0.0014 0.16 14.1 3.8 1 23 489 511 489 511 0.97

12 12 6.7e-05 0.0076 18.2 2.8 2 23 518 539 518 539 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.001	0.12	14.5	2.6	1	21	162	182	162	183	0.96
2	12	0.087	10	8.4	2.2	1	23	201	224	201	224	0.90
3	12	0.00051	0.058	15.5	1.3	1	21	236	256	236	257	0.95
4	12	0.0057	0.65	12.2	2.5	2	23	274	296	273	296	0.96
5	12	0.031	3.5	9.9	1.4	1	22	310	331	310	333	0.90
6	12	0.0005	0.057	15.5	2.2	1	23	338	361	338	361	0.98
7	12	2e-06	0.00023	23.0	4.3	1	23	372	394	372	395	0.96
8	12	0.012	1.4	11.2	1.7	1	23	400	422	400	422	0.97
9	12	6.4e-05	0.0073	18.3	1.4	1	23	433	455	433	455	0.99
10	12	0.0042	0.48	12.6	5.6	1	23	461	483	461	483	0.99
11	12	0.0014	0.16	14.1	3.8	1	23	489	511	489	511	0.97
12	12	6.7e-05	0.0076	18.2	2.8	2	23	518	539	518	539	0.98

Sequence Information

Coding Sequence: ATGGACCATTGGTGCCGCGTTTGTCTGGATGAAACAAAGGGAGAACTTCTGTCCATCGAGCATGAAGTGGAAGGCTTGTCGATTGATCTGTTGATTACCAGCTGTAGCGGGATTACGGTTGAAAAATCGGACTCGTTACCCGGAAAGTGCTGTGAGCGATGCGTGAAAAGTTTATACATCGCATACAGTATAGCGGAACAATGTCGTGTTTCGGACGAGAAGCTGCGTAATCTCAACAAACTCTCAACCGAATCGAACAAAGCGGAAACAGTACACGATGTCTGCGCCGAGATTTCCAACGACTCTAGTGATGATGCTGAGAATCACGGCGAGAATAATACACATACTGACACTGAGAAAACATGTAAATTAATAACCACATGTTGTGCATGCAGGGCTGACTTTGAAACGGTTGAAGCTCTTGCTGATCATGTTGTGAAAGTCCATGAGCCAGACAAAACAGACAATGATAGCAAAAAACCGTATCAATGCGATATTTGCTATAAGAGGTATTTTAAAAAGACTTCTTTGAATCGCCACAAAAGACTGGGTACTTCAGGTCTAGGGATTCGAATCGCGCAAATAGAACAACCCATCGATTATCGATGCTGTGGATGTAGGAAAGATTTTCTCACCAAAGAAGAACTTCAGAATCATTCTGTGTCAGAGCACAGCTTAGATAAAGTTCATGATGAATCGAAGCCGTTTCAGTGTGATATTTGCTTTAAACGGTATTCTAACAAAACGTCTCTTGGAAGACATTTCCGTGAGCGTCTCGTGAATAGACGCCCTCGCTCTATTCGGAGACTCGCTAGTAATCAGTGCTGTGGATGTCGGCAAACCTTCAATAGCAAGGAATTGCTCAGTCAACATGCCAGGCAAATCCACGAACCAGACCGAATGGAGGATCTGGGTGGACTAAAACCATTCGAATGCAGCGTCTGCTTCAGCAGATACTCCACTCAGGAAGCATTCAATCGTCATAAGGCGTTCCTCCATCTGGATCAACTGTACCAGTGCCAACAATGCGAGAAATTCTTCGTGAAACGTATTATGCTTCGAATACACGAGCGAAAGTTTCACAATGGCATCCAGCAGGATGTTGTTGGTCCCTATCAGTGTACCCGTTGTGGGAAAACGTTCATGCAATCGAGTTCTCTCACCAATCACGAGAAAACACATCACAGCGATGAACGATTCGAATGCTACATTTGCCAAAAACTCTTCCTTAGTAAAGGTAATCTACAAACTCATTTCAAGCTGCACTCTAAGCCAACCGCACAACGTAAAGCACAATACGAATGCCCGATCTGCCGATGTCGGTTCAAAACTCCCAACTACCTGGATATACATGCAAGAACTCACAGCGGAGAGAAACCATACACATGTAAGTACTGCTCGAAGCAGTTCGCACATGCTTCCGGCCACAAGCGTCATCTGCTCACTCACACTGGGTTGAAGCCATTCTCGTGTCGATTCTGTGGAAGGGAGTTCTCAAACCGAACGAATATGCACATCCACGAGAAAAGCCATGGGACGGAACGAAATGCAAAGTGCGATGTGTGCGGGAAGGAATTCGTTCACGATCGATATCTACGAAAGCATTTGAAACGGCACTCGAGTTCATGA
Protein Sequence: MDHWCRVCLDETKGELLSIEHEVEGLSIDLLITSCSGITVEKSDSLPGKCCERCVKSLYIAYSIAEQCRVSDEKLRNLNKLSTESNKAETVHDVCAEISNDSSDDAENHGENNTHTDTEKTCKLITTCCACRADFETVEALADHVVKVHEPDKTDNDSKKPYQCDICYKRYFKKTSLNRHKRLGTSGLGIRIAQIEQPIDYRCCGCRKDFLTKEELQNHSVSEHSLDKVHDESKPFQCDICFKRYSNKTSLGRHFRERLVNRRPRSIRRLASNQCCGCRQTFNSKELLSQHARQIHEPDRMEDLGGLKPFECSVCFSRYSTQEAFNRHKAFLHLDQLYQCQQCEKFFVKRIMLRIHERKFHNGIQQDVVGPYQCTRCGKTFMQSSSLTNHEKTHHSDERFECYICQKLFLSKGNLQTHFKLHSKPTAQRKAQYECPICRCRFKTPNYLDIHARTHSGEKPYTCKYCSKQFAHASGHKRHLLTHTGLKPFSCRFCGREFSNRTNMHIHEKSHGTERNAKCDVCGKEFVHDRYLRKHLKRHSSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -