Basic Information

Gene Symbol
-
Assembly
GCA_029784135.1
Location
CM056649.1:38598798-38601393[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.0073 0.84 11.8 0.3 2 23 130 152 129 152 0.91
2 17 0.014 1.7 10.9 0.0 3 20 164 181 162 183 0.91
3 17 8.3 9.5e+02 2.2 2.9 2 19 313 330 313 335 0.93
4 17 0.00015 0.018 17.1 3.0 1 21 345 365 345 366 0.95
5 17 0.23 27 7.1 0.1 1 20 373 392 373 394 0.96
6 17 0.11 13 8.1 0.8 3 23 421 442 421 442 0.94
7 17 0.66 76 5.7 3.2 1 20 455 474 455 476 0.94
8 17 0.22 25 7.2 0.3 1 21 483 505 483 510 0.92
9 17 0.15 18 7.7 0.4 4 23 534 556 532 556 0.87
10 17 0.077 8.8 8.6 0.1 3 21 574 592 572 593 0.93
11 17 0.0032 0.37 13.0 0.2 1 21 599 619 599 620 0.94
12 17 1.7e-05 0.0019 20.1 0.2 1 23 628 650 628 650 0.98
13 17 4.9e-05 0.0056 18.7 0.1 1 23 656 679 656 679 0.98
14 17 0.00072 0.082 15.0 1.4 1 23 685 707 685 707 0.98
15 17 0.097 11 8.3 2.6 1 23 713 736 713 736 0.92
16 17 0.37 43 6.5 1.6 1 23 742 764 742 764 0.98
17 17 0.14 16 7.8 0.7 1 23 770 793 770 793 0.93

Sequence Information

Coding Sequence
ATGGCCAGCATGGATGCCTACTGCCGAGTTTGTATGACCAAGGATTCTGTGGAATTAGTATCGCTGTTTCAAATTCATAACGGCGAGGAAGAAGTTATTGCTAACATGATTATAGACTGTACTGAAGTAATGATATCTGACGACGATAAACTACCACAAAATATTTGCACAGAATGCTTGATTCGCCTAGATAATGCGTTCGAACTGCGGAAGCAGTGCCAACGCTCGGATGTGGCTTTCCGTAATATGCTAACCCAGACCAAACATGTTAAGGAAGAAGGTGGAATGAAAATAACAATAGACATGAAGTTGACTGACCTTACAGAAAACCTATATAGATTTGTTGAAACTGGTAAGTACCACGATGTGGTACAAATAACAGGTATTCGTTGTTGCGGTTGCAATGCAGTTTTCAATACGGAGTCAGAACTAGAAATACATTCGTTGAACGCCCACAAGAAACAGGAAAAAAACCCCGCTCCACATCTGTGTCCCATTTGCGGGCAAATTTACCCTAATCGTAATGATCTGATGGATCATGGAAAAGATGTACCATACAGTTATAATGTATGTCGCTTGTGTGGACTAATGTTAGGATCGAAGATCGATATTTTCGGGCATTTAGAAACCAGTCATAACATCATTGAAATGCGTGCGGAATCAAACCATAAAGTTATTTCATTCGATGCTGCAGATATAGTTTGCCCACAAACCGATGAAGAGCATGAGATAGAATATCttgatgaagcagaagattTAGAGTTTGTCGACAAAGTAAATGAAGAACGAACCGATGAACAACAAACAGCAGATGATGGGGAGGACGCTCTCACGGACAGAGCAGATTCAGAACACGAATCAAAAATGCCCAACAACGTGTTCATAGATTCCATTGATGACTTACCATGCCACAAAGTTTACCATTTACGTGGCGAACGATGCTGTGGTTGTTACGAAATGTTTGATGACATCGAAAAGCTCAAAAACCATTGCGAACTTGAGCACTCCATTTCGTATTCGAATAAACAAAAGCATCAATGTAAAGCATGTAACCGGTGTTTCAAAAACAATGCGCAATTAGAAAAACATATCCAATCAGCTAATCAAAAAACAATTTACTATTGCAAACTTTGTGATTTGATACTGACAGATGATAGTAAATTTACAAGTCATATAGTGCTTACCAATGATCATGATGAGGCGATTAGCAGTAGTAAAATCGGTGATAAATTCGAAGAGATTTCAGCTGGAAGTACTGGATGCTGCGGTTGTGATGTGGTATGCGACAGCGAAGTTGAATTGCGTAGACATATCGAAGAGGAACATAGTCAGAAATTGTCTTCTATTGATAATGAAGATCAGTTTGAATGCAACCGCTGTTTCGATTGTTTTCCTACGTCCCACCAACTTACACTGCACAAGGCACAAGCCCAGAATAGGTTGTACTACCAATGTCGCACTGAGGATTGTGGGTATAGAACACCAGATAAGAAACAAATAGTTAAACACGTCACCACGACTAATGCCCATAGAGACCTCTCGCATAAGCAACCAACGAAACGGAAGAAAAAACAGCCGAAGGACGACAATATGACTTGTTGTGTTGCACGTTGCTATGAAACTTTCAACTCCTATGAAGAACTTCAAATCCATGCAGAGACTGCTCATGAACTTCTGCGTATTCAGCACACACAGAGCCGAAAATCGGAAAACACGGCATGTGATATTTGTTTCAAAGGTTTCGAAAATGTACAGGCTTACACGCGACACCGAATGGTCGACAGAACTCGTAAACATGTTTGCCTAACTTGTGGTGCGCAATATGTTTCTAAATCGAACCTTATTCAGCACGAGAGAAGTAATTGCGGAAAGATAGCCACATTCCAATGTACGCAGTGTGATAAAGCCTTCGTTACAGTTGGTGGTCTCAAAAATCACCAAGAGGTACACGGTAACAAGAGATCGTTTGTTTGTGACATATGTGGGCGTGCGTTTCTTCGCAAAAGCGTTTTGAATGATCATATGAACACGGTTCATTCTACGTTGCGCCTTTTCAAGTGTTCGCTTTGCCCGAAATCATTCGCGAGCCGGAATATCTTCCAGTCACATCAGCTAACTCACACAAAGGAGAGACCTTATCAATGTAGATATTGTGATAAGCGTTACTTCAAAACCAGCGACAGAACATTACACGAGAATCAAGTGCATCTCGGAATAAGGCCCTTCCAGTGCAGTTTCTGCTCTTCTTCTTTTATTCGAGATCGCGAGAGGAGGCTTCACGAACGTATACACACAAAATCAAAACTGTACACATGTGACATATGTTCTGGAGGATATAATAAGTTTTCAGAATTCAAGCAACATCGGCTGGATGAACATGGTATTGAAACTCTGCGTGACCTAGGGCCCACTGTGATGGCCGCATTGAATGGGGATTCCGTGGGTGAAATCGATAATGATTCGTGTATCGAAGATGTTGAGCAAAGCGGGTTCAAAATGGAGATCGATATTCACGAGTCCGTTTACAAAGATGAATAA
Protein Sequence
MASMDAYCRVCMTKDSVELVSLFQIHNGEEEVIANMIIDCTEVMISDDDKLPQNICTECLIRLDNAFELRKQCQRSDVAFRNMLTQTKHVKEEGGMKITIDMKLTDLTENLYRFVETGKYHDVVQITGIRCCGCNAVFNTESELEIHSLNAHKKQEKNPAPHLCPICGQIYPNRNDLMDHGKDVPYSYNVCRLCGLMLGSKIDIFGHLETSHNIIEMRAESNHKVISFDAADIVCPQTDEEHEIEYLDEAEDLEFVDKVNEERTDEQQTADDGEDALTDRADSEHESKMPNNVFIDSIDDLPCHKVYHLRGERCCGCYEMFDDIEKLKNHCELEHSISYSNKQKHQCKACNRCFKNNAQLEKHIQSANQKTIYYCKLCDLILTDDSKFTSHIVLTNDHDEAISSSKIGDKFEEISAGSTGCCGCDVVCDSEVELRRHIEEEHSQKLSSIDNEDQFECNRCFDCFPTSHQLTLHKAQAQNRLYYQCRTEDCGYRTPDKKQIVKHVTTTNAHRDLSHKQPTKRKKKQPKDDNMTCCVARCYETFNSYEELQIHAETAHELLRIQHTQSRKSENTACDICFKGFENVQAYTRHRMVDRTRKHVCLTCGAQYVSKSNLIQHERSNCGKIATFQCTQCDKAFVTVGGLKNHQEVHGNKRSFVCDICGRAFLRKSVLNDHMNTVHSTLRLFKCSLCPKSFASRNIFQSHQLTHTKERPYQCRYCDKRYFKTSDRTLHENQVHLGIRPFQCSFCSSSFIRDRERRLHERIHTKSKLYTCDICSGGYNKFSEFKQHRLDEHGIETLRDLGPTVMAALNGDSVGEIDNDSCIEDVEQSGFKMEIDIHESVYKDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-