Basic Information

Insect: Toxorhynchites rutilus
Gene Symbol: -
Assembly: GCA_029784135.1
Location: CM056649.1:21909550-21924158[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 9.5e-05 0.011 17.8 0.9 1 21 510 530 510 531 0.94

2 8 8.4e-07 9.6e-05 24.2 2.9 1 23 562 584 562 584 0.98

3 8 0.00051 0.058 15.5 2.5 1 19 598 616 598 620 0.93

4 8 1.9e-06 0.00022 23.1 2.2 1 23 626 648 626 648 0.99

5 8 0.0001 0.012 17.7 6.1 1 23 654 676 654 676 0.98

6 8 1.1e-06 0.00012 23.9 0.8 1 23 682 704 682 704 0.98

7 8 2.3e-07 2.6e-05 26.0 1.0 1 23 710 732 710 732 0.99

8 8 1.5e-05 0.0017 20.3 6.7 1 23 738 760 738 761 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	9.5e-05	0.011	17.8	0.9	1	21	510	530	510	531	0.94
2	8	8.4e-07	9.6e-05	24.2	2.9	1	23	562	584	562	584	0.98
3	8	0.00051	0.058	15.5	2.5	1	19	598	616	598	620	0.93
4	8	1.9e-06	0.00022	23.1	2.2	1	23	626	648	626	648	0.99
5	8	0.0001	0.012	17.7	6.1	1	23	654	676	654	676	0.98
6	8	1.1e-06	0.00012	23.9	0.8	1	23	682	704	682	704	0.98
7	8	2.3e-07	2.6e-05	26.0	1.0	1	23	710	732	710	732	0.99
8	8	1.5e-05	0.0017	20.3	6.7	1	23	738	760	738	761	0.96

Sequence Information

Coding Sequence: ATGGATCGACTCCGCATCAGACTATTCGCTGCGGTCAGACGTTTGCAGAACATCGCTACAAGAGTCAACACACCGGATCACGATTCAACCAGCTGCGATTACCTCAACGCTGAACGAGAAAGTCTGGTTGAAGCATGGGGAGACTACTTCATCATCTTCGATGAGCTTCTTGAGCAACGTGGCGGCGATATCTTCTCCTTCGAGTTAGTGAAAAATAAGCGTGAAATGGAGAGACTGTACAAGTCTACGGAGGCTGCGATCGACGAGCGACATCGCATTGCCTATCCCAGCGACAGTACAATCTTTTCTTCATCACCGGCGGAGGCAGCGACGGACGAGCGAAATCGCTTAGCCTCCCATCGAGACGACGCACAATCGACTACAGATCCTTACGGCGACTCTGATCAGGTGACAGTTACGACAACCTCAACAACGACCACTCAATGGTATGCAGGCCGACTCACATTGTATAGTAAAGTTTCTGATCCTGCATACATTGTGGTTGCCGAGCAATACAAGCTATCATCCACCAATCCAATCAAGTCAACGGCTGCAGCGATGGACCAGCGAAGTCGCTCATCCTACCAACACGACAGCAATTTTCACCCTACGAAATCTCCAATGCATACAAAGGCAGCGATGGACAAGCTATATCGCTTAGCTCTTCATCTAGACCACGTATCGTACACATCAGCTTACTCACAGCAGGACATCAAGCCTTCGGCATTCTGCCTAGCTGCCGCAAAAGAGAGGCCAACATCGTCTACGACGTTGGCGTTCGATCCAGGCGGACAGAACACATCGCAATGGGAAGCAACGGAACAAAATTTAACGCTCTACAAATCAACGCAAACCAATTGCATCGCATCGAACGCCACTCAAATTGACGATACGAGCACACATGAAGGCCATGTAAGTCTACGCAGCACACGAAACCTCGAATCAATTTGCAACGCCTCGAATCAACTCAAGCTCATCAGTTCTTCACGGGACAAATGTAGTTTTTGTTCCGATGAATGCAATAAGAAATTCCAATACGCGCTGATACCCCCTCGCCAAGAGCCGAAACTAAAAACTGTGCTGCAGAAACTTAGCAGTTCCGCTTCCGAGTTAAGTAGTTATCCTACATGCGACAAATGCCACCAAGAATTAATGACCGTCTACAAGATTCCTGAAAGTTGCTTCCAGATTGTGCCCAATGCCAAACCTACACATCACATCAAGATGGAACCGGAGTTAATGATTGATGACCACGAACTGTCGAAAACTGGCAAAATTTTTGAAGGAGATTCAACAGTGGACTTTGGCTCGATTGAACCGGAAGACCAAATGGGTATCGAGGGACAAAATGGAGAAGTATTCTTCATCAGTGAAATAGACGAAGACGCAAGAACAAATACACAAAAAACAGGGGAATTGGAACAGAATGAATTTCACCCATCTTCAGAACGTCATAAATGTAAGAAGCGATTGGCGGACGAAAATTTGATTAAAGATCCCATACGGTTACGCATGGAAGGAAAACGGTTCAAATGTGAAAAGTGTGAAAAAACATTTAGCACTAATTACAGGCTAAAAGAGCACGCGAACGTCCTTATTCTTGCCCAGATTGTTCAACATCCTTCGCAAACGCTTCAGCATTTCGACGTCACATTCGAATTCATACAGGTTGGTGAAAGTCCCTTTTCCTGTCAACAATGTCCGAAGACGTTCAAACGATCTACGACGCTCAAAAAGCATATTCTAACTCATCAGGATTCGGGAGATATTTCAGATAACCGAGATAAACCGTTCAAATGTGAAAAGTGTGGAAAGCCATTTGGAACGAAATACAAGcttaaactacacgattttacTCACACGGgtgaacgtccctattcttgtccacattgtctGAAAGCGTATAAGCATCCTTCAGCACTCCGAGAGCACATTCGAACCCATACGGgtgaacgtccaTTTTCCTGTCAACATTGTTCGAGAGCGTTCAGGAATCATCAGACACTCCGAGAccacattcgaactcatacggATGAACGTCCGTTTTCCTGTCCGCACTGTCCGAAAGCGTATAACGATCGTACGACGCTCATAGtgcacattcgaactcatacggGAGAACGTCCCTATTCCTGTCCACATTGTTCCAAAACGTTTACGAACCTTGCTGCGCTGCAGGTGCACATTCGAAGCCACACCAAAGAGAAGCCTTACGTTTGCGAGCATTGTAAGCGAGCTTATGCCCAGTCTCACAATCTTACCAGACACCTTCGTCGTCACCACAGCAGTATACCGAACCATTCGAGCCGTAAACACGATCAGTTCGATACGGATACAGGCGGCTCGGAACAGGAATCACAGGTGACCGTGAAGGAAGAGATAACTGGTTGTTGA
Protein Sequence: MDRLRIRLFAAVRRLQNIATRVNTPDHDSTSCDYLNAERESLVEAWGDYFIIFDELLEQRGGDIFSFELVKNKREMERLYKSTEAAIDERHRIAYPSDSTIFSSSPAEAATDERNRLASHRDDAQSTTDPYGDSDQVTVTTTSTTTTQWYAGRLTLYSKVSDPAYIVVAEQYKLSSTNPIKSTAAAMDQRSRSSYQHDSNFHPTKSPMHTKAAMDKLYRLALHLDHVSYTSAYSQQDIKPSAFCLAAAKERPTSSTTLAFDPGGQNTSQWEATEQNLTLYKSTQTNCIASNATQIDDTSTHEGHVSLRSTRNLESICNASNQLKLISSSRDKCSFCSDECNKKFQYALIPPRQEPKLKTVLQKLSSSASELSSYPTCDKCHQELMTVYKIPESCFQIVPNAKPTHHIKMEPELMIDDHELSKTGKIFEGDSTVDFGSIEPEDQMGIEGQNGEVFFISEIDEDARTNTQKTGELEQNEFHPSSERHKCKKRLADENLIKDPIRLRMEGKRFKCEKCEKTFSTNYRLKEHANVLILAQIVQHPSQTLQHFDVTFEFIQVGESPFSCQQCPKTFKRSTTLKKHILTHQDSGDISDNRDKPFKCEKCGKPFGTKYKLKLHDFTHTGERPYSCPHCLKAYKHPSALREHIRTHTGERPFSCQHCSRAFRNHQTLRDHIRTHTDERPFSCPHCPKAYNDRTTLIVHIRTHTGERPYSCPHCSKTFTNLAALQVHIRSHTKEKPYVCEHCKRAYAQSHNLTRHLRRHHSSIPNHSSRKHDQFDTDTGGSEQESQVTVKEEITGC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -