Basic Information

Insect: Toxorhynchites rutilus
Gene Symbol: Zfx
Assembly: GCA_029784135.1
Location: CM056649.1:103340115-103345342[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.27 31 6.9 0.1 1 23 365 387 365 387 0.95

2 11 0.022 2.5 10.3 1.0 1 23 393 420 393 420 0.98

3 11 0.026 3 10.1 0.5 1 21 424 444 424 445 0.95

4 11 0.0031 0.35 13.0 3.9 1 23 455 477 455 477 0.97

5 11 2.2e-07 2.5e-05 26.1 1.8 1 23 485 507 485 507 0.99

6 11 2.3e-05 0.0026 19.7 5.8 1 23 513 535 513 535 0.98

7 11 0.00033 0.038 16.1 0.7 1 23 541 563 541 563 0.98

8 11 1.8e-06 0.00021 23.2 0.3 1 23 602 625 602 625 0.98

9 11 0.0064 0.73 12.0 2.9 2 23 634 655 633 655 0.94

10 11 0.00049 0.055 15.5 2.8 1 23 661 683 661 683 0.98

11 11 0.00083 0.095 14.8 0.7 1 23 689 711 689 711 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.27	31	6.9	0.1	1	23	365	387	365	387	0.95
2	11	0.022	2.5	10.3	1.0	1	23	393	420	393	420	0.98
3	11	0.026	3	10.1	0.5	1	21	424	444	424	445	0.95
4	11	0.0031	0.35	13.0	3.9	1	23	455	477	455	477	0.97
5	11	2.2e-07	2.5e-05	26.1	1.8	1	23	485	507	485	507	0.99
6	11	2.3e-05	0.0026	19.7	5.8	1	23	513	535	513	535	0.98
7	11	0.00033	0.038	16.1	0.7	1	23	541	563	541	563	0.98
8	11	1.8e-06	0.00021	23.2	0.3	1	23	602	625	602	625	0.98
9	11	0.0064	0.73	12.0	2.9	2	23	634	655	633	655	0.94
10	11	0.00049	0.055	15.5	2.8	1	23	661	683	661	683	0.98
11	11	0.00083	0.095	14.8	0.7	1	23	689	711	689	711	0.98

Sequence Information

Coding Sequence: ATGGTACGTTTGTGCTGTATTCCAATCTGTCGCAACGCGAAAGCTAGCTGCGATAACGGAGCGGGCTTACACCGTTTCCCAGCAGATCCTGAGTTACGTAGAAAGTGGATTGAATTTGTCGGTGCCGATCCAAACAAATTCCGCTGGAGGACTAAATGTATCTGTTCGGATCATTTCTCCCACTCCGAACTTATAGAAGAAAATGGGCAGATAAAGCTGCTAACGGGGGCCGTACCTATGGCATTCTCCTGCGAAGACAACGAAGAAGATGACAGCGTTATGCGGGAAGATGTGATGACATCGGAAGAACCTTCCACTGCGAGTATTGCAGAAGACGGAACAGCAATTGAGGAGATTGAACTGAGATCGTTGTTTTGTCGAATTTGCTTAAGGAAACAGCCCGTTTTGTTGCCTCTCAATTCAAAGCTACACAACGCGACACTAACCGATATCATCTACACAATCTCCGGAACAAAGCTCGATTGCAGTGGTATGGTTCCTACGAAAATTTGTATGGGATGCGTTTCGAAAGCTGATCTAGCTTTCAAAGTTCGCATTGAGTTCATACATAATGAACGAATATTACAAAATTTGCTAAACAACGGAAAACTGGAACACCATTATATATCTTATGAGGCTAATGGATGTGCCCCCAAGGATGTAAATGAAACGTACTTGAATGATTTGATTTCGGCTGTCAAACACGAAGTCACGGAACAGCCGCTCGAAATTCAACAGCCCAAAAAGGGAGGAAAGGGTCGCAAGCAGAGCCCTAAGAAGCAGCTATCAACCACACATGTTGAGATTGACACAACGGATCCATCGGAAGATACCGAAGAATTCTTCCTGGAAGAACATTTAAATGAGGAACTTGAACAGGAACCGGAACTAGAGGAAAAAGATGTACCATATATAGAACATGCTAGTTCTGCGAACATATTGAAGCAGGAAATAGTGTCGGATTCTGAGAACGAAAGTGATAGTaccacgaaaaagtacgtttacTCGTGGACGGAATTGTGTAAGCCAAAAGCAGCTCCCAAACCGAAGAAGCTTGTTATCGAAGACCGTCCGAAGCCCAAGTTTGTTCCATACACCTGCTACATCTGCGACACATCGCACGCCGATGCCGATGCACTTGATATACACCTGGAAGAGCACGTTGGTTTGCTGCCATACACCTGCGATGATTGCAACACGCCAACGCATCCTTTTGTCTACAAATCGCTGACTGCGCTCAACAAGCATCTCCAAACCCATTTGTATCCGTACAAGTGTCATGAATGTCCGCTGCGTTTCCTGGACAAAACTGCCCTTGGAACACATTTACGCTACAAACGTGATGATGAAAACAAGGATGGCCACACGTGTGATTACTGTGGACAATTCTTCACTATGAAGCGACGATTTAAGATACATATCGCGAAGCATATCGCGTTGGAAAAGGGTAAATACAAATGTGAACACTGCGGCAAGACGTTCGGTGACAGTAATCTTCTTAGGCGGCATGTTAGGATACACACAGgCGAGAAACCGTTCGAGTGCAAGAAGTGTGGCCGCCGGTTCAACCATGAGGATAACTTTAAAAACCACAAACGTTCCCACATTGGAGAAAAGGCATACATCTGTGatgtttgcaaaaaaaatttcgttaaTGGAACCTATCTGCGTTATCACATGGCGAAGCACTACCCGGATGATCCGAAATATAGGGTTCAGAAGAGGGCCCCACCGAGGCCCCGCTACGATACTGAGGGTCAGGAGACTACCACACATTCGAATCGGAGAAAGGCACAGAAGATATTCCAATGTGAAGAGTGCGATAGGCcgttttcattcaaatatttaCTGACCGAACACATGGCAACCGTGCACGGGATTACACCGGAGCGAAGCCTAGAGTGTCCGTACTGTTCGAAGTCATTCAAGAACAGGCAGAGACTCAATTGCCACATAGACAGCCACGAAAACAACCGACGCTACAAATGCAAGTTCTGCGACAAGTCCTTCGTACAGAAGGTGAATTGTGTGGCTCATGAACGGATTCACACTGGTGAAAAACCGCACGTCTGTAGGATTTGCCCGGCTGCATTTGTCACCTCCTCCGGGAGGAAGAAACACGAAAGAACACATCAGGGGGTAGAAATCATTCTGGCGGATAGTGTTCCAGAAGAACAACTCGAGGAAGTAATTAAGGATGAAGATGATAAAGAAATTGTTTCAACAATTTAA
Protein Sequence: MVRLCCIPICRNAKASCDNGAGLHRFPADPELRRKWIEFVGADPNKFRWRTKCICSDHFSHSELIEENGQIKLLTGAVPMAFSCEDNEEDDSVMREDVMTSEEPSTASIAEDGTAIEEIELRSLFCRICLRKQPVLLPLNSKLHNATLTDIIYTISGTKLDCSGMVPTKICMGCVSKADLAFKVRIEFIHNERILQNLLNNGKLEHHYISYEANGCAPKDVNETYLNDLISAVKHEVTEQPLEIQQPKKGGKGRKQSPKKQLSTTHVEIDTTDPSEDTEEFFLEEHLNEELEQEPELEEKDVPYIEHASSANILKQEIVSDSENESDSTTKKYVYSWTELCKPKAAPKPKKLVIEDRPKPKFVPYTCYICDTSHADADALDIHLEEHVGLLPYTCDDCNTPTHPFVYKSLTALNKHLQTHLYPYKCHECPLRFLDKTALGTHLRYKRDDENKDGHTCDYCGQFFTMKRRFKIHIAKHIALEKGKYKCEHCGKTFGDSNLLRRHVRIHTGEKPFECKKCGRRFNHEDNFKNHKRSHIGEKAYICDVCKKNFVNGTYLRYHMAKHYPDDPKYRVQKRAPPRPRYDTEGQETTTHSNRRKAQKIFQCEECDRPFSFKYLLTEHMATVHGITPERSLECPYCSKSFKNRQRLNCHIDSHENNRRYKCKFCDKSFVQKVNCVAHERIHTGEKPHVCRICPAAFVTSSGRKKHERTHQGVEIILADSVPEEQLEEVIKDEDDKEIVSTI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01471491;
90% Identity: iTF_01471491;
80% Identity: iTF_01471491;