Basic Information

Insect: Toxorhynchites rutilus
Gene Symbol: ZBTB41
Assembly: GCA_029784135.1
Location: CM056647.1:15582600-15586820[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.0014 0.16 14.1 1.6 1 23 245 268 245 268 0.98

2 18 0.0028 0.31 13.2 2.2 1 23 275 297 275 297 0.97

3 18 0.0015 0.17 14.0 0.8 1 23 303 326 303 326 0.96

4 18 6.8 7.8e+02 2.5 1.0 1 21 338 358 338 361 0.76

5 18 0.02 2.3 10.5 2.3 3 23 382 402 380 403 0.94

6 18 9.6e-05 0.011 17.8 2.5 1 23 422 445 422 445 0.97

7 18 0.0035 0.4 12.8 5.5 1 23 450 473 450 473 0.96

8 18 0.0091 1 11.5 1.8 1 23 485 508 485 508 0.96

9 18 0.041 4.7 9.5 1.6 1 23 527 550 527 550 0.90

10 18 0.00026 0.03 16.4 4.0 1 23 557 579 557 579 0.98

11 18 0.007 0.8 11.9 0.4 3 23 587 608 585 608 0.92

12 18 4.8e-05 0.0055 18.7 1.8 2 23 663 684 662 684 0.95

13 18 0.0027 0.31 13.2 1.2 1 23 690 713 690 713 0.97

14 18 0.016 1.8 10.8 3.0 1 23 725 748 725 748 0.95

15 18 0.061 7 8.9 0.7 1 23 774 796 774 797 0.95

16 18 0.0008 0.091 14.9 5.1 1 23 804 826 804 826 0.99

17 18 0.02 2.2 10.5 0.8 1 23 832 855 832 855 0.95

18 18 0.0074 0.85 11.8 0.3 1 23 865 888 865 888 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.0014	0.16	14.1	1.6	1	23	245	268	245	268	0.98
2	18	0.0028	0.31	13.2	2.2	1	23	275	297	275	297	0.97
3	18	0.0015	0.17	14.0	0.8	1	23	303	326	303	326	0.96
4	18	6.8	7.8e+02	2.5	1.0	1	21	338	358	338	361	0.76
5	18	0.02	2.3	10.5	2.3	3	23	382	402	380	403	0.94
6	18	9.6e-05	0.011	17.8	2.5	1	23	422	445	422	445	0.97
7	18	0.0035	0.4	12.8	5.5	1	23	450	473	450	473	0.96
8	18	0.0091	1	11.5	1.8	1	23	485	508	485	508	0.96
9	18	0.041	4.7	9.5	1.6	1	23	527	550	527	550	0.90
10	18	0.00026	0.03	16.4	4.0	1	23	557	579	557	579	0.98
11	18	0.007	0.8	11.9	0.4	3	23	587	608	585	608	0.92
12	18	4.8e-05	0.0055	18.7	1.8	2	23	663	684	662	684	0.95
13	18	0.0027	0.31	13.2	1.2	1	23	690	713	690	713	0.97
14	18	0.016	1.8	10.8	3.0	1	23	725	748	725	748	0.95
15	18	0.061	7	8.9	0.7	1	23	774	796	774	797	0.95
16	18	0.0008	0.091	14.9	5.1	1	23	804	826	804	826	0.99
17	18	0.02	2.2	10.5	0.8	1	23	832	855	832	855	0.95
18	18	0.0074	0.85	11.8	0.3	1	23	865	888	865	888	0.93

Sequence Information

Coding Sequence: ATGGACAATGAAGCCATTCCGGATGTCCCGAATGATGATCCGGAAACATACTGCCGGTTGTGTTTTTCTGGATTCTACGTGGAACCCGTGTTTCCGCACGATGCCGAACCCAAACAGGATCTGCTCGATTTGATAGCGAAGCATGTCGAGATACATATCACGCCCGAAGCCGACTATCCGTGTTCGGTGTGTCGGATGTGTCAAATGACACTGGAGGGATTCCACAAGTATCGGGAGCGCTGCCGCAGACTCGATGAAGTGCTGCAGCAGAAACGGCTTGAGATGATCCACATGCGGGTGAAGGTCGAACATCAGGAGCAGCTCGCTCAAAATGCGGTGGGTTTCGAGGACAATACGATTTACTGTCTCAGCGATACCGATGATGAAGATCTGGGGGAGGAGGTGATGGACGGGGTACATGGAGATTTGGGCGAAGACCATCAGGATGAACTTCTAGATGAGGAGGTTGAAGAGGAACTGATTAAGGGGGATATATTGCTTAAACCAGAACCGTACGATATGGATGAGTATGGACAGACTTCTCACGGCGTGGCCAGTACGCACCCGGTGGAATCATACGGCAAGGACGACGTTGTAGTGCTTGATTCCGAGGAGGATGAAGAACAGTCGATGGAAGCATCCACTAGGGCTAGTAGTGAGGCACATGGTGAAGATTATGCTAAAGATGAACCCACGAAATCTTTACCATTTGAAGTCACCTCCGAcggagcatatcgttgtacgATTTGTAAGGAAACAtttagactaatgaaggaaatTAAGACACACATCCGTAAGGACCATCCACAGGAATCACAAATTTATTCTTGCCGATTTTGTGCAAAAAAGTTTTCGGACACGGGATCGCTACGTGTGCACACCAGGTTTCATACGATGGATTTTCCATACTCCTGTGATGAGTGTGGTGCTAAATTCACTATGAAAAACCGCCTCGAGAAACACACGGCTCGTTATCATGACAAGGATTCGCCAAGTTACACAGACAAACGGTTCACTTGTTCACTCTGTCCGCGAATTTTTCTTCAGGAACAAGCCCGCAATATGCATATTACTCATTTCCACGACGTCAAGCTCACCGATGTTCCGGTAGAAGCCAATCTTTCATTACAGCAGGTGTTGttctgtgaacagtgtaatgaATCGTTCGATTCGAATGGCACTTTCAACGAGCACAACCAGAAGCATCATCAGACGGAAAGCGAGGAAACcaacgaaaaatcaaaaacaaaggTAGCGAAAAGGTACAAATGTCCAGATTGCAGTAAGCTGTTCCGTCATCGCACAGCCTTTCGGTCACACATTATGATAAATCACGGTACGATGCCTCACAAGTGTGACGTTTGCGGAAGCTGCTTCGAGCGGAAAACTAAGCTCACGAAGCACAAGGAGCGATGGCACGGAGAGAACGCCAAGAACAAAGTTTTAGAGCGGTATAAATGCGATCATTGTGAACGGTACTTTGTGCGTAATCAAGATCGTGTTCGGCACGAACAAATTGTTCACAGCATTGAGTCCCCTGCGAAATTGCCAGCGGTTTGGGAGGGCAGGAAGAGTAACTTCCCATGTTCCAAGTGCGACAGGAAGTTCCCCTCCATGAAAACCATGAGAATACACTTCTCGTTGAAGCATCCGGAGGTTCCGGTGCGATTTAAATGTACGGTCTGTTCCAAGCTGTTCAAGCACAAAACTTCCCTGCGTGATCACATGGCGAACCACACCGGACAGCAGCCATACGGATGTGTGCACTGTGAAGAAAGGTTTGTTCGTAAAAAGGATATGGAGCGGCATCTGGAGGCCGCCCATGGTGCGGATGGAGCGACTATCGAACATAAGGAAACATTCGCTTGTGGGTATTGCCCGAGAAAGCTACTTTCGAAGACAGCTAGAGCACTCCACATACGGCACCACCACTCAGACAAGGAGGATTTCACGAAACAAGTTTTGCTTTCCCTTCCGGATTCGCTAGTTTGTTCACATTGCGACAAGGTATTCACCAACAGAAATACCCTCAAGTTGCATGTTCTCAATCATTTGGGTAAGCTCCCACATCAATGCGATCAATGCGATGCCGGTTTCTATAAACCGGCCGATCTCCTAAAGCACAAACAGCGCTATCACACCGGAGGATCCTCGCTAAGTTTGGCGAGTCGCTTCAAATGTGCTTACTGTCCACGTATCTTCATCCGGAAGTCAGCCCGCCGCTACCACCACACCGTGTTCCACGGTATGCTGTCAAAGAAAAATGTTCCTGCAAAACCGGGAGCGAAAAAACGCATCAAGCCCGACCCAGATATGGAGTATCCTTGTGCACTTTGTTCGCTCGTTTTCGTTACCGTTCCGATGCTCGAGACCCACCATCAACAGCACCACTCCGACCAGGAATTCTTCTACAAGTGCCCCCACTGTCCAAAACGAACGACTCATCGAAACACTTACCTGTCCCATATAAAGGTCCACGTCGGAGGCTACCGACATCCGTGCGACGAATGTAATGCCCAATTCGATCGGAGGATCCTTCTGGTGAGTCACAAAAGACTGTACCACAGCACGTCGGGCAAGGAAACCCCTCGTTTCCAGTGTTCCCTGTGCCCGCGGGAGTTTATCCGCAATCAGGATCGCGTACGACATCAGGTCAATGCGCATAACTACCGAGTGCAAGGGAGTAATGCACAAAGCCCGGGACCTTCAAAGCCTACGGTCAAAGGCAAGGGGAAGATAAAGCTTAAGATTAAGAAGGAAAGAATGGTCCACGAGAGTACGACGCAAGACGGGGAGAGTCAACAGCAGCAACAAGTTGATGCGAAAACGGAAGCAGTTGTCGAAAGGTCACGGGATGGTTTTTATGTCTCGAGTGATGTGGAGGAATATGAAATACCGGATGACGACGAGGAGGATGCGACGCAGGATGGAGCACAGCAAAATCCAAAAGAAGGGGATGCCGAGACAGAAAGTCAGGCATCGGTGCCCACCATTTCCAATGTGGTGTCAATCAAGCAGGAAGCGATTTCGGCGCGTAGAGGATACATTTACAGTAGAAGGAAGGAGGAATCTCTGAAAAAGCAGTTCGAAAAAAAGGACGATACGAGTTTGTGTGACGCCGGCCAAAAATTTCGCTGCTCCTATTCCTACATCCACAAAACCCTCAAGCAGGAGGGCATCGTCTGTAAGAAGAAGACTATGTCCCCAGAGTACACGGGCGAGCTAATAGCGACCGTGAAATCTCCGGCCGGCACACCGGCACGAATGACGAAGAATGATCACGGGACATCGTTCGTGCTGGACGACGAgagttattttccgctgtcaaagTTCCACATTCCCGGCAATGACCGGTACTATACCAGCGACAAGGTGTTCACACTCCCCGGGGTGAAGTACAAATACAAGCATAAGTTAGAGAAGAAAGTTATGCTGTATATTGCAATCTCCGACAAATGGATTCCAAAGCCAtggtcttctggccggacaagccGTCTTCcaattacgccaagaagacgttggCGTACCTCGAGGGAAAACAGATACCGTACGTTCCCCGAGGAACGGAACCCGACCAGCTTGGCTCAGTGCCGTCCGATCGAGGATTTTCTCGGCTTCCTCAGTGCTGTCAttcactga
Protein Sequence: MDNEAIPDVPNDDPETYCRLCFSGFYVEPVFPHDAEPKQDLLDLIAKHVEIHITPEADYPCSVCRMCQMTLEGFHKYRERCRRLDEVLQQKRLEMIHMRVKVEHQEQLAQNAVGFEDNTIYCLSDTDDEDLGEEVMDGVHGDLGEDHQDELLDEEVEEELIKGDILLKPEPYDMDEYGQTSHGVASTHPVESYGKDDVVVLDSEEDEEQSMEASTRASSEAHGEDYAKDEPTKSLPFEVTSDGAYRCTICKETFRLMKEIKTHIRKDHPQESQIYSCRFCAKKFSDTGSLRVHTRFHTMDFPYSCDECGAKFTMKNRLEKHTARYHDKDSPSYTDKRFTCSLCPRIFLQEQARNMHITHFHDVKLTDVPVEANLSLQQVLFCEQCNESFDSNGTFNEHNQKHHQTESEETNEKSKTKVAKRYKCPDCSKLFRHRTAFRSHIMINHGTMPHKCDVCGSCFERKTKLTKHKERWHGENAKNKVLERYKCDHCERYFVRNQDRVRHEQIVHSIESPAKLPAVWEGRKSNFPCSKCDRKFPSMKTMRIHFSLKHPEVPVRFKCTVCSKLFKHKTSLRDHMANHTGQQPYGCVHCEERFVRKKDMERHLEAAHGADGATIEHKETFACGYCPRKLLSKTARALHIRHHHSDKEDFTKQVLLSLPDSLVCSHCDKVFTNRNTLKLHVLNHLGKLPHQCDQCDAGFYKPADLLKHKQRYHTGGSSLSLASRFKCAYCPRIFIRKSARRYHHTVFHGMLSKKNVPAKPGAKKRIKPDPDMEYPCALCSLVFVTVPMLETHHQQHHSDQEFFYKCPHCPKRTTHRNTYLSHIKVHVGGYRHPCDECNAQFDRRILLVSHKRLYHSTSGKETPRFQCSLCPREFIRNQDRVRHQVNAHNYRVQGSNAQSPGPSKPTVKGKGKIKLKIKKERMVHESTTQDGESQQQQQVDAKTEAVVERSRDGFYVSSDVEEYEIPDDDEEDATQDGAQQNPKEGDAETESQASVPTISNVVSIKQEAISARRGYIYSRRKEESLKKQFEKKDDTSLCDAGQKFRCSYSYIHKTLKQEGIVCKKKTMSPEYTGELIATVKSPAGTPARMTKNDHGTSFVLDDESYFPLSKFHIPGNDRYYTSDKVFTLPGVKYKYKHKLEKKVMLYIAISDKWIPKPWSSGRTSRLPITPRRRWRTSRENRYRTFPEERNPTSLAQCRPIEDFLGFLSAVIH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -