Trut032746.1
Basic Information
- Insect
- Toxorhynchites rutilus
- Gene Symbol
- -
- Assembly
- GCA_029784135.1
- Location
- CM056649.1:6627056-6637576[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 3e-05 0.0034 19.4 0.8 1 23 176 198 176 198 0.97 2 15 0.039 4.4 9.6 3.0 1 23 204 226 204 226 0.96 3 15 3.9e-05 0.0044 19.0 0.2 1 23 346 368 346 368 0.98 4 15 0.074 8.4 8.7 0.4 1 23 374 397 374 397 0.97 5 15 0.0025 0.28 13.3 1.4 1 23 439 462 439 462 0.96 6 15 2.2 2.5e+02 4.1 0.0 2 23 514 535 513 535 0.93 7 15 0.098 11 8.3 2.8 1 23 541 564 541 564 0.95 8 15 0.058 6.6 9.0 1.2 2 19 572 589 571 590 0.95 9 15 0.0022 0.25 13.5 8.6 1 23 603 625 603 625 0.95 10 15 0.037 4.2 9.6 0.6 2 23 631 652 630 652 0.97 11 15 1e-05 0.0012 20.8 1.3 1 23 658 680 658 680 0.98 12 15 0.0085 0.97 11.6 0.2 3 23 688 708 686 708 0.97 13 15 0.00062 0.071 15.2 0.5 3 23 716 736 714 737 0.95 14 15 0.03 3.4 9.9 0.2 1 23 751 773 751 773 0.96 15 15 0.025 2.8 10.2 0.1 1 20 1244 1263 1244 1266 0.93
Sequence Information
- Coding Sequence
- ATGGAACCGTCCACATTCACAATCTGGGATCCTTCACAGTCCAGTGCTAAGATGAAGATAATAAATATTCCGGGACAGGGTCCTACGCAAATGATTGAAAGCGTTTCCGGTATTGGTAGCACTGGAATATCTACGTCGGCTGAACAAATAATCCTGCAGACTCATGACGGGCGGGAATATCTTGTGGACGGGATTGGTCATATCGATCAAAGTCCCCCGGAAAACTTGATCTACATGGCAGCCGACGATGGTTCGCTCATCCAAGGTGAAGTAATCCATGTGCAGGGAGAGAACAGTACCACTGGTGCTGAAGTAGGAGGAGAGATAGTTCAGCAGGATCAGGAGTACATGGAATGTGAGGTCACCGAGGAAGTTATTACCGACGATTGGGTCCAGACGGATGGACAAGAGTGTGTTCAAGTCACCGTTGACCAACTGGGAGCAATGGCTGTAATTGGAGCACAGGACGATGATATCACAGTGCCGCTTCCCACCGATCAAGACGAGTACACGACGTTGCGTCCGTATCCATGTGATTTCTGCAGCCGGAGGTTTCGCAAGAAAGCGAATTTGATGAATCACATGATTGCTCACTCTAACGATAGACCACATATTTGTAATTTGTGTGGTGCACGGTACATGAGACGATGCGACTTGTTAAATCATCTTAAGTTGCACGCGTACACTGCGGATGACCATGAAGAACCTCTGCCCCAGAGTGATCCAGAGGATGACTATGATTACGACTTCACAAACTCATCACCGACAACGCTTCAAAAACGTTCGGATTCTACGGAAGAAGCCGAGGGCTTGTTGGTACCAGCGCCTTCTCAGTACAGGGCACCAGCGGCGAGAGTTGTTCCCAAAAAAAGTCGGACCAAACAAGTTCCGAAATCGCAGAAAAGAGTCCCTACCTCAATCATTCGTTCGCGCGTTCCGCCATCCAAACCTGCAACGGAGAACAAATTCAGTGTCCCAGTAGAACCATACGTCGATATTCCTCCTAGGTTCCCGGTTACGGATGAACGGAAACCTTTCGTCTGTCAAAAATGTGGAGTTTCTTTTGCAAGAGAGAAAGCACTCGCATCGCACTACCGCATCCATGGCGGAGATTCGCCGTTTGAGTGCGAAACGTGCGGTGATAAATTCTGGGATCGTACAATGCTACAGGACCACATTAGACAGCGACACGCGGCGAATTTCATGGCTCCATCGATCGAGCAAACATCGTCTTTTACATATAGTCCACAAATTCATAACCCACAGGATCAGGTGGAAGATGAACATTCTGAGGATGAATCCATTGAGCAGTACTTCTATTGTGACAGTTGTGGTTTATCGTTTTTAAAACAGGAACAGCTCAAGCGTCACATAAAACAAACTCACGGTATTAAAGAGCAGAAATATGAACCAATTAGTCAGATTGTCCGGCAGCGgcaacagcatcaacagcaggtGATTGCCGAGGAAGATTACAACGATGAAGAGGAAGAATATAACGACAACAACGGCAACGAGAACGAACCGCAGCGGCCCTTGTCTTGTAATGTATGTGGTGACATCTTTGCTGAAGCACTGGATTTGCTCGCACATGCTGAAATACACGCTCGATTCGAGCCACACAGATGCCAGTTGTGTCCTTTGACGTTTGTGGACGAGAAAACTATCAAAGAGCACATTCAACAATGCCATAGTCACGAGTTGACGGACACTTCCTGTGTGATTTGTGGGAAATTCTGCAAAAATCATGCTGCTCTGCTGAAACACGCCTGGGAACATTCGCGAGAGCGCGCCAATTATGGTTCCCATTGCTGTTCGAAGTGTGGAAAAACGTTTCACAACAAAGCTCGCCTCAAGCGGCATATGGTCTCACATCGGAACAAATCTGTCAAGTGTGAGGTTTGTTCGGAGGAATTTCCAGACGGGAGAAGTTTAATGAACCACAGACATTCGCACACCAAAACGAGACAATTCCCATGCCACGAGTGTGGAAAGACGTTTGGTTCCAGATCGTCGCAGCAAATCCATTTGCGTATACACTCCGGAGAACGACCTTACGGATGCAGATTCTGTTGGAAAGCGTTTGCGGACGGAGGAACGCTTCGAAAGCACGAGCGAGTGCACACCGGCGAGAAACCATACGGTTGCTCAGTATGCCCGCGAGCATTTAACCAGCGAGTTGTGCTGAGGGAACACATTCGATCTCATCATTCGGCTCCGGACACCAAGCGAGGCACCGCCATCCAGCCATACTTTTGCTCCGTATGCACCCAACTGTTCGAAACATCGATCGAACTCATTCAACACTTGATTCAGCACAGTGACACGAATACGGCGATGAAAAGACAACCCCCGACCTTCCCGAGGAAGTACAAACGCAGGAGGAAACTCAAACCGGACGAGGTTGAGAAAATGGGCAACAGTAAAGGCAGGATGAAAAATAACACCGTGGTGACTCACACAGAAACCGTACAGAATCTAATGAAAATAGTGGAAGACGAGGaactgttgaaaaatcctgCAGAAGTTTTGCTCGAGTATGGTGCCGGAAACTCGGATAGGAAACTTGTAGCCTCGTCAAAGTATGTGAATTCCTATGAGCTGTTAGCCTCGGCATCTGCCAGCCACACAAAACCTGCAAACTTGGATGACAGCGGTATAAACCTACTGAGCAACGTTGTCTTAGTGAGTAATCCGAGTTCCAGTGGTGAGAAGAAAGTGAAACCTATAAAAACCGAATCTCCCAAGCGTCGAGGGGGAAAACAGACATCTCCATCAAATGCTTCCAGAGCACTGGGTGGCCAAACGAGTTCTTCCGCATCCGGATCACGTCCTCGTATGATACACACTCAAAAAACTCGTGTCCCAGTGACAGACGGCAAACGCAGGACCAGAACGGTTATAACCAAAGACATAAAAAGCCAACCAAGCAGCAATTTCTCTCCGTTGGAATTTGAACGGTCAAGAAACCGTCCCGTTCTTACGTATCGAGAAATTCCTTCGGAAAGAATTTCATCCGAAAGTTTTCCACTGCTAGACGACGGTCGAGAGGTTGACGCTGACGTAGATGATAGAAATCAGGAAGCACTTGATGTTCTTACTACCAGCACCAATAAGCTGCACCAACATGAGGTACCCAGCTATGAGGATCTGTTgaatcaaaatttgttgatggAGATTTCACGTAAGGATAAGTTTATTGACAAGTTCAATAGCGATATCGTGAACGACTTGGAAGAGATTCTTCGTTCACCTATTAAATGTGCCAGCAATAGTGGACCACCAGCAGTTATAATGGCCACACCCAAAGCCAATCGATACAATAATGTTAGTCATCAGAAGGAACTATACGATCAACCGACTGCAGAAGATGATACAAACTTTACTGCTGAAGAAGAGGATCCGAAGCCTTCGAAGACCCCCCGAAAGCAACAGCCGAAGAAAATAACTAAAGAATCTGCCCAGCGTTCTCTGACTTCCGCGTTACGCAGTCAACGTCTCACACGCCGACAACTAGAGCGAGAAGTCAACTTTTTGAGAGAGGCATACGCTCCCGATCTAACAACTGTCAACATAAAACAGGAAAAAGATAGTCCCGATAAACTATCAGCCATGCTTTTGAACGACATTCAAACTCCACAAACCCTACTCAATCCCAAATTGGAACCAACGCAGGATACACAGATGGAAAATGGTGTCTCGACAGTACCACCTCCCCAACCGGAGCAATTCCAGTGCGAAATGTGCTCCGCATTATTCAGTGATCGTTCGCAGCTGCTGCTGCACGTACCAATTCACATTTGA
- Protein Sequence
- MEPSTFTIWDPSQSSAKMKIINIPGQGPTQMIESVSGIGSTGISTSAEQIILQTHDGREYLVDGIGHIDQSPPENLIYMAADDGSLIQGEVIHVQGENSTTGAEVGGEIVQQDQEYMECEVTEEVITDDWVQTDGQECVQVTVDQLGAMAVIGAQDDDITVPLPTDQDEYTTLRPYPCDFCSRRFRKKANLMNHMIAHSNDRPHICNLCGARYMRRCDLLNHLKLHAYTADDHEEPLPQSDPEDDYDYDFTNSSPTTLQKRSDSTEEAEGLLVPAPSQYRAPAARVVPKKSRTKQVPKSQKRVPTSIIRSRVPPSKPATENKFSVPVEPYVDIPPRFPVTDERKPFVCQKCGVSFAREKALASHYRIHGGDSPFECETCGDKFWDRTMLQDHIRQRHAANFMAPSIEQTSSFTYSPQIHNPQDQVEDEHSEDESIEQYFYCDSCGLSFLKQEQLKRHIKQTHGIKEQKYEPISQIVRQRQQHQQQVIAEEDYNDEEEEYNDNNGNENEPQRPLSCNVCGDIFAEALDLLAHAEIHARFEPHRCQLCPLTFVDEKTIKEHIQQCHSHELTDTSCVICGKFCKNHAALLKHAWEHSRERANYGSHCCSKCGKTFHNKARLKRHMVSHRNKSVKCEVCSEEFPDGRSLMNHRHSHTKTRQFPCHECGKTFGSRSSQQIHLRIHSGERPYGCRFCWKAFADGGTLRKHERVHTGEKPYGCSVCPRAFNQRVVLREHIRSHHSAPDTKRGTAIQPYFCSVCTQLFETSIELIQHLIQHSDTNTAMKRQPPTFPRKYKRRRKLKPDEVEKMGNSKGRMKNNTVVTHTETVQNLMKIVEDEELLKNPAEVLLEYGAGNSDRKLVASSKYVNSYELLASASASHTKPANLDDSGINLLSNVVLVSNPSSSGEKKVKPIKTESPKRRGGKQTSPSNASRALGGQTSSSASGSRPRMIHTQKTRVPVTDGKRRTRTVITKDIKSQPSSNFSPLEFERSRNRPVLTYREIPSERISSESFPLLDDGREVDADVDDRNQEALDVLTTSTNKLHQHEVPSYEDLLNQNLLMEISRKDKFIDKFNSDIVNDLEEILRSPIKCASNSGPPAVIMATPKANRYNNVSHQKELYDQPTAEDDTNFTAEEEDPKPSKTPRKQQPKKITKESAQRSLTSALRSQRLTRRQLEREVNFLREAYAPDLTTVNIKQEKDSPDKLSAMLLNDIQTPQTLLNPKLEPTQDTQMENGVSTVPPPQPEQFQCEMCSALFSDRSQLLLHVPIHI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -