Basic Information

Insect: Toxorhynchites rutilus
Gene Symbol: ZNF219
Assembly: GCA_029784135.1
Location: CM056648.1:12564127-12569213[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0044 0.51 12.5 1.5 1 23 99 121 99 121 0.96

2 11 0.0018 0.2 13.8 2.7 3 23 129 150 127 150 0.95

3 11 8.8e-06 0.001 21.0 0.3 1 23 156 178 156 178 0.99

4 11 8e-07 9.1e-05 24.3 0.2 1 23 184 206 184 206 0.99

5 11 0.03 3.5 9.9 5.3 1 23 212 234 212 234 0.98

6 11 8.2e-06 0.00093 21.1 3.3 1 20 240 259 240 263 0.95

7 11 0.079 9 8.6 6.1 1 23 269 289 269 289 0.97

8 11 1.4e-05 0.0016 20.4 0.0 3 23 297 317 296 317 0.98

9 11 2.9e-05 0.0033 19.4 1.1 1 23 323 345 323 345 0.99

10 11 7.2e-06 0.00082 21.3 0.3 1 23 351 374 351 374 0.97

11 11 2.1 2.3e+02 4.1 1.3 1 19 380 398 380 401 0.81

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0044	0.51	12.5	1.5	1	23	99	121	99	121	0.96
2	11	0.0018	0.2	13.8	2.7	3	23	129	150	127	150	0.95
3	11	8.8e-06	0.001	21.0	0.3	1	23	156	178	156	178	0.99
4	11	8e-07	9.1e-05	24.3	0.2	1	23	184	206	184	206	0.99
5	11	0.03	3.5	9.9	5.3	1	23	212	234	212	234	0.98
6	11	8.2e-06	0.00093	21.1	3.3	1	20	240	259	240	263	0.95
7	11	0.079	9	8.6	6.1	1	23	269	289	269	289	0.97
8	11	1.4e-05	0.0016	20.4	0.0	3	23	297	317	296	317	0.98
9	11	2.9e-05	0.0033	19.4	1.1	1	23	323	345	323	345	0.99
10	11	7.2e-06	0.00082	21.3	0.3	1	23	351	374	351	374	0.97
11	11	2.1	2.3e+02	4.1	1.3	1	19	380	398	380	401	0.81

Sequence Information

Coding Sequence: ATGAAGCGGGCTCGTCAAAGTAAGGCTACTACCAAATCGACTTCAGAGGCCGCTAAACGGAAAACCAGGAAATCGGACATCCAAAGAGAGAACAATAACAACGAACCGGTGATTTCAAATGAATCAGAAGCAACAAAACCGATTGATGAACCAATTCAGCCAGAGATAGAGGAGGATCTGGAAAACAGTGTAGTCGAGTCGGCTGTCGATAACGAAGCTGCCGCTGGTGCTGCATCATCCGTATCGGAGTCCGAGAATGAAAAACAATCCGGTAAGAAAAAGGAACGAAAAGTGTACCTCTGTCAGGTGTGCCATAAGAATTTCCTAGGCATCAGTGATTTACGGAAACATCTTCGGATACACAACGACGAACGGCCGTACGGTTGTCAGCACTGTGGAAGCCGGTTCCGGCAAGCTGGCTGTCTGAAGAATCACATTGCTTCCCAACATGGAACGGACACGTTGTATACATGCGATCTTTGTGGGAGGTCGTTCCCGATCAAGGAGCGGTTGCGGTTGCACATGAGAGTTCATACTGGGGAAAAACCCTACAAATGCCCGAAATGTCCGAAGACGTTCGCGCGTGGTGGTCAGTTAACTCAGCATCTTGCCACTCATAACGGTGTACGGAAGCATAAATGTCCCCACTGCACGTCTGCATTTTCGTGTGCTGCCAATTTGAGGATGCACTTGAAGAGCCATTTCGACATTCGGGATTACACGTGTCATATCTGTGGCAAAGGATTCTACCGGCCGGATGCACTGAAGAAACACCTCCTGTGCTATCATGCAAACCTCAAGGCTTTCCACTGTAAAATATGCAACAAAATGTTCAAAGGTCATCTTCCGCAGCACATGAGAACCCACAAGATGATTCGTCCGCACGGCTGTGCCGTTTGTGGTGCTGTTTTCTCCCAGCGGTCGCAGCTGGTGGTTCATCAGCGTATCCACACGGGTGAGAGACCCTATCGGTGTCAGGTTTGCTGGCAAGCCTTCGCTCACTCGAGCGTTCTCAAGCTGCACATTCGCAAACACACCGGAGAGAAACCGTTCGAATGTCCCATTTGCAGTGTGGGCTTTTCGCAACTTCCACACTTGAAGAAACATATGCTCTCTATACACAATCAGGATAAATCGTATCTATGTAAGAATTGCAATgtctttttcaaaacaaaactagaCCATCAAAATCACGTTACATCGTGTGCACCGGAAACAGCACAAACGCCAACCAGTGTTGAAGAGATTATTGATCGAAATGTTAAAGCAGCTAACAGTGGAGTCGATCCCCCAATGCCACTGTCTAACATGAGATTCCTGGTAGCGATACTGCTTAAAAAAATTTCGACCGAAGAGCGATTGAAAGATTTAGGATTTGATAAGCGTTTAATCGATAACGTTTTAGTTGACTCGTTGAAATGCGCTGGTCGCAAGGTATACGAAGATAAAACAATGGATCCGGCTCTTCGTCTGAAACAAAACGTCCAAGAACTGCTCGAGTGGACCGTTCCGGTCAAGTATATGGAAGAGTTCAAAAAAGCTAATCGAAGTACCGAGGAGTTGTTGGAGGATTTGACCAATTAA
Protein Sequence: MKRARQSKATTKSTSEAAKRKTRKSDIQRENNNNEPVISNESEATKPIDEPIQPEIEEDLENSVVESAVDNEAAAGAASSVSESENEKQSGKKKERKVYLCQVCHKNFLGISDLRKHLRIHNDERPYGCQHCGSRFRQAGCLKNHIASQHGTDTLYTCDLCGRSFPIKERLRLHMRVHTGEKPYKCPKCPKTFARGGQLTQHLATHNGVRKHKCPHCTSAFSCAANLRMHLKSHFDIRDYTCHICGKGFYRPDALKKHLLCYHANLKAFHCKICNKMFKGHLPQHMRTHKMIRPHGCAVCGAVFSQRSQLVVHQRIHTGERPYRCQVCWQAFAHSSVLKLHIRKHTGEKPFECPICSVGFSQLPHLKKHMLSIHNQDKSYLCKNCNVFFKTKLDHQNHVTSCAPETAQTPTSVEEIIDRNVKAANSGVDPPMPLSNMRFLVAILLKKISTEERLKDLGFDKRLIDNVLVDSLKCAGRKVYEDKTMDPALRLKQNVQELLEWTVPVKYMEEFKKANRSTEELLEDLTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00400850;
90% Identity: -
80% Identity: -