Basic Information

Insect: Toxorhynchites rutilus
Gene Symbol: -
Assembly: GCA_029784135.1
Location: CM056648.1:67061002-67095471[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 4.3e-05 0.005 18.8 1.8 1 23 301 323 301 323 0.94

2 11 2.8e-06 0.00032 22.6 1.0 1 23 329 351 329 351 0.98

3 11 0.0005 0.057 15.5 0.1 1 23 357 380 357 380 0.91

4 11 0.0013 0.15 14.2 5.3 1 23 386 408 386 408 0.98

5 11 0.016 1.8 10.8 3.8 1 23 414 436 414 436 0.99

6 11 3.6e-05 0.0041 19.1 1.9 1 23 442 464 442 464 0.97

7 11 4.3e-05 0.0049 18.9 1.0 2 23 471 492 470 492 0.95

8 11 2.7e-06 0.00031 22.6 2.9 1 23 498 520 498 520 0.98

9 11 1.1e-05 0.0012 20.7 2.8 1 23 526 548 526 548 0.99

10 11 3e-06 0.00034 22.5 0.3 1 23 554 576 554 576 0.98

11 11 6.5e-06 0.00075 21.4 3.7 1 23 582 604 582 604 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	4.3e-05	0.005	18.8	1.8	1	23	301	323	301	323	0.94
2	11	2.8e-06	0.00032	22.6	1.0	1	23	329	351	329	351	0.98
3	11	0.0005	0.057	15.5	0.1	1	23	357	380	357	380	0.91
4	11	0.0013	0.15	14.2	5.3	1	23	386	408	386	408	0.98
5	11	0.016	1.8	10.8	3.8	1	23	414	436	414	436	0.99
6	11	3.6e-05	0.0041	19.1	1.9	1	23	442	464	442	464	0.97
7	11	4.3e-05	0.0049	18.9	1.0	2	23	471	492	470	492	0.95
8	11	2.7e-06	0.00031	22.6	2.9	1	23	498	520	498	520	0.98
9	11	1.1e-05	0.0012	20.7	2.8	1	23	526	548	526	548	0.99
10	11	3e-06	0.00034	22.5	0.3	1	23	554	576	554	576	0.98
11	11	6.5e-06	0.00075	21.4	3.7	1	23	582	604	582	604	0.98

Sequence Information

Coding Sequence: ATGGCCAAATCGACCGTGTGCAGCGTTCTCAAACGTTTCCGTGAGATGCATACTATCGATCGGCAGGTTCATACCAGGCGTCATAGTGGAACTAAGGATCGGAAACTGCatttgaaggtgttgagaacGATCAAGGCAAACACAGGGCAGTCGGACTATGACATCGCCAAGAAATTCAATGCCGACCGGTGCACCGTCCGGTGTCTGCGCCAAGGAATACGATCTTATCGGACCAGTAAGCAACCAAACAGGACATTGAAGCAGAATGTAGTAGCCAAAGGACGTGCCCGGAAGTTATACAACAAGGTTCTAACGAAGTACGACGGATGCATcctcatggatgacgaaacgtacgtgaagatggattttgggcaGCTTCCAGGCCAAAAATTTTATAATGCCACTGGCCGGGGTGATGTCCCCGGCAAGTTCAAATTCATTTTTGCCGATAAGTTTGCGAAAAGCTTCAACCTGGACATTGGTGATCAAGCATTGGACATTGGATCCCTCATATCGGACGACTCCATATTCGGCACATTGTTTCAATCCGGCGACATAAACGAGCACCTGGAGCAAACATCATTCTCATCATCGTCCTTGTCGTCATCGCCGTCGTCGTCGTCAGACTTTGGGACCACAGCATCACTAACGACTTACCCTTCGTCACCGTCGCCATTGCTGTTTCAATTGGACACGTTTACCCAGCAGCAGCACCAACAACCGACAGTGCTGAAACCGCACAAATGCACATTGTTCAACGATGACAAGTTGAGTGACCTGGATTCGGGAATTTCAAGCGGCGCTTCTGTGGACTGCGAGGAGTTGGATTGTGAGGCATCGCCCTCGGAAGAGTCAACTAACGGTAGCGATGCTGAAAATGATGAACCCGAGTTCAGACCGTTCAATTGCTCCGAATGTGGCAAAAGCTACACCCGGAAGCTGTACCTAATGCGACATTATGTCCAGCATACCCGGGAGCAGCCCTATCGGTGTGAGGTGTGCGACAAAAGCTTTGCCTACGCGAGTTCACTGTCCACACACAGAAAGCAACACCTGGTCAGCCACGAGTTTAGGTGTGAAATTTGCAGTCGAACTTTCCCCTCGGAGGATCTGTTGGTGGCCCACAAAACGGCCGCACATTACAGCGATCGGCCATTCAAGTGTAAGCTTTGCAAAAAGACGTTCGTTCTGCAGCATGCATACAAAAATCACAAGAGATGGCATCAGCAGTTCAACCCTTACAAATGCATGGTGTGCGATAAGCAGTTTATGAAGAAAATCAGTTTGAAGTGTCACCTGAGGGTACACACGGGTGAAAAACCATTTTCTTGTGATATCTGCAATAAAAGTTTCACTTTGTCCTCCACGCTGTCATCCCATAAGAAGCTACACGGTGAAAAGCCCGCTCTGCAGTGTGAAACATGCGGTAGAGTTTTCACCCAAGCTAGCGCTCTTTCAACACACAAGCATCTGCACACGGAAACTCGGCCCCACAGTTGTGACCTCTGTGGCAAACGATTTATAAGATTACACGCCCTGAAAATCCACATTCGAACCCACTCCAATGAGCGACCCTACCGATGCGATACCTGTCCGAAAACTTTCTCCGAGAAGCATGTTTTGATTAGGCATCTCAAGACACATACCAACGAGCGGCCATACAGCTGTGACACCTGTGGGAAGGCATTCAAGGAGAAGTACGATCTCTTGCGGCACGTTCTCATCCATTCCGGCGTAAGGCCCCACAAATGTGACGTGTGCTCGAAAACTTTTGTGCAGTCTAACGCCTTGACCAAACATCGGAGGAGACACGCGCGGGTTGAGACGGTGGCTGACAAGGAGATGACTGTTACAGTAATGGAAGATAGGTGCGATACTCCACTCAGTACGCAAATGCTGGATGGTGAGGTGTTAGATACATAA
Protein Sequence: MAKSTVCSVLKRFREMHTIDRQVHTRRHSGTKDRKLHLKVLRTIKANTGQSDYDIAKKFNADRCTVRCLRQGIRSYRTSKQPNRTLKQNVVAKGRARKLYNKVLTKYDGCILMDDETYVKMDFGQLPGQKFYNATGRGDVPGKFKFIFADKFAKSFNLDIGDQALDIGSLISDDSIFGTLFQSGDINEHLEQTSFSSSSLSSSPSSSSDFGTTASLTTYPSSPSPLLFQLDTFTQQQHQQPTVLKPHKCTLFNDDKLSDLDSGISSGASVDCEELDCEASPSEESTNGSDAENDEPEFRPFNCSECGKSYTRKLYLMRHYVQHTREQPYRCEVCDKSFAYASSLSTHRKQHLVSHEFRCEICSRTFPSEDLLVAHKTAAHYSDRPFKCKLCKKTFVLQHAYKNHKRWHQQFNPYKCMVCDKQFMKKISLKCHLRVHTGEKPFSCDICNKSFTLSSTLSSHKKLHGEKPALQCETCGRVFTQASALSTHKHLHTETRPHSCDLCGKRFIRLHALKIHIRTHSNERPYRCDTCPKTFSEKHVLIRHLKTHTNERPYSCDTCGKAFKEKYDLLRHVLIHSGVRPHKCDVCSKTFVQSNALTKHRRRHARVETVADKEMTVTVMEDRCDTPLSTQMLDGEVLDT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -