Trut014310.1
Basic Information
- Insect
- Toxorhynchites rutilus
- Gene Symbol
- Zfp646
- Assembly
- GCA_029784135.1
- Location
- CM056648.1:28408068-28410741[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 4.5 5.2e+02 3.1 0.2 1 19 175 193 175 197 0.72 2 15 0.31 35 6.7 4.9 1 23 208 230 208 230 0.96 3 15 0.0023 0.27 13.4 0.2 1 20 235 254 235 256 0.93 4 15 0.0037 0.43 12.8 4.2 1 23 281 303 281 303 0.96 5 15 0.014 1.6 11.0 0.3 1 20 309 328 309 330 0.94 6 15 1.8e-06 0.0002 23.2 4.0 1 23 537 559 537 559 0.99 7 15 0.0025 0.29 13.3 0.0 1 23 565 587 565 587 0.93 8 15 1.3e-05 0.0015 20.5 0.3 1 23 593 615 593 615 0.97 9 15 0.00018 0.021 16.9 0.7 2 23 619 640 618 640 0.96 10 15 5.6e-06 0.00064 21.6 0.5 1 23 646 668 646 668 0.96 11 15 0.0039 0.45 12.7 3.0 1 23 674 696 674 696 0.98 12 15 1.2e-05 0.0013 20.7 0.2 2 23 704 725 704 725 0.96 13 15 2.7e-05 0.0031 19.5 5.1 1 23 731 753 731 753 0.99 14 15 2.9e-06 0.00033 22.5 0.8 1 23 759 781 759 781 0.98 15 15 0.0024 0.27 13.4 0.1 1 22 787 808 787 811 0.91
Sequence Information
- Coding Sequence
- ATGAACAATTCTCAAAATATTGTTGTGTATGGTTACACTCTTGGGGACCAGATATACCAAATCAAGCAAGGTAATGTGCAATCAAATTCCGTCCCAACGAGAACAATTAGCACCATACTTTGTCCGGATAACATCGTTCAAATTGTACCAGCATGCACAGGGACTATTATTCAAGCTCAGCCACCAATCATCCGATTTGTGGAAAATGTACAACATCAGGAAGTTATCCACCAGATTGAAGTGAATCACGAAAAGGTGCCTACAATCCATTCTTCGGCCAACAATTATACAATTCTCAATACAGCAACAGTAACAATTGAAAATGATAGCATCAATGGTGAACAACCATCATCTGTTTCTGGCCCAAAACTAGATTCTGTTCAGATCGGCGAAGCTACAGCAGAAGCCCCACAAAAGTCTAATCAGATCTCCGTAAACCATGAGAGAACCAAGAAAAGGAAACATTTGACAAAATCTCCTACAGCGAAGCCTGTCACCccgaaaacgaaaaaagatTTCATCTACGAATGCGACATCTGTGACAGTCGCTTCCTGGCCGTCACATCGCTGAAGTTGCACAAAACCGGCCACCGATACGTCTCGGTGGAGGAGAAGAAAGCCTTCTGCTGTCGGTTCTGTGGGCGCCAGTTTTCCCACATGCAAACGCTGGGCGACCACGAGAAGGTGCACATCGATGATCGGTACAATTGTGGCGCCTGCGGTACGAAGTACAGCTCGAAAAGTGGCCTCCGAAATCATCTGGCGAAAAACGGGGAATGTGATGCCCACTACCAGCAAAGCAAACTACAGCGGAAGCGGCAAGACGAGGAATTCAAGGAGCATGAGTGCGAAATTTGCGGGAAGAAGTATCGGCACCGGAAGTCGATGCTGGAGCATCGCAGTTTGCACTTCCGGAACAAGCAGCATAAGTGCGAGCGTTGCGGGGCAATGTTCGAGACGAGCGGCGGTTGGAGGAAGCATACTACGAACGGAAGGTGTGAGTTTTCGAAGAGTAAGTTCAAAGATCCGGGCGGTAGCGATGAGGTTTTTATTCCCGAGGAGCGGAAGAAATTTTTGGAACAGATGCAAGAAACGAAGAAGAAGGAGCGGAGAACGGAGATAATCAAGAAACGTAAAAGTAGACtgaaggaaaatgtgaaaaatagcAGCAGTGACAACGAAGACGAATCTGTTAGCTTTGGTACAGATCATAATGAGTCATCTGGAGAGGAGGAAGTAAGTCCAAACCCGACTATAGAGCTTGTAACAGTGCCGGAAATCTCTTCGAAAATAGTTCCCGAATCCAAAGAGGAAGTCCAAGATGAGCAAGAAATCGCAATTGATTCGATTGATGTTGATTTCGAGATCAAAGAGGAAGTTCCAAGCGATGAGGAAGCGACCAGTCTACAAAAGGCGAAAGATGAGAAGGAACAGAGTGACGTGCAATTATCAGAAAATGAATGTTTTAATCAAAATGAGCAATCCGCCGAAATTGAGGATGAATCTCACAAAGATGACAAACAATTAGAATCGCAACCTACCGAAGATGTGTTGGGCGATGGACAACCAAAGCTGAAACCTCCAAGAGGTcataaaaactcgaaaaattatgAGTGTCCAACCTGTCACAAATCATTCTCCCGGAAGTTTGTGCTCACAAACCACCTACGAACTCACACAGGCGAACGACCCTATCTCTGCGATAGCTGTCCAAAATCCTTCGGGGACGCGGCATCGTTGAAAATGCACGTCGTTATTCACACCGGAGAGAAGCCGTTCCAATGCAGCGAGTGTCCTGCGCGATTCGCTCGAAAAAGTGGTCTCCGCAATCACATCACGCTTCACTTCAATCTTCCCTGTGACGAGTGCGACCAGAAGTTCCCATCACGCAAAACGCTGATGCGTCATAAGATCAAGCACCAGGGAGTTCGACCGTTCCTTTGTGAAATTTGCTCCAAAGACTTTCGCACCAAAGCCGACATGAAGGCCCACATGCGGATCCACTCGAACGAAAAACGCTACAGCTGTAAAATCTGCTCGGCCCGCTTCAACTGTCCGTCAACGCTGCGAAGGCATAGGAACGTTCATGCTCCACCGGAAACGCGCCCGGTTTGTGAAACGTGCGGGAAGCCTTTCTCTTCCCAGCAAGCCCTTCGGAAGCACGAGAATATCCACAAGGATTTGAAACCCTTTCAGTGTTATATTTGTTTCAAGCGCTTTCGGGTGAAGGATCACCTGAAAATTCACCAGCGATCGCATTCGGGTGAGAAACCGTTCTCGTGTGATGTCTGCGAGAAGAGGTTCGTCACGAATGGAGACCTCAAAGTTCACTACCGGCGGCACACGGGAGAGAAGCCCTTCAGCTGTGAGGAATGCGGACAGGCCTTCGTAGTTACGGCTGGGCTTTACAGACACCAACAGCAAACGGGTCATAAAAGTGGTAAACCGCAAGCAATCATCGTGGCGGAGTACACGCGGGCTACGTGA
- Protein Sequence
- MNNSQNIVVYGYTLGDQIYQIKQGNVQSNSVPTRTISTILCPDNIVQIVPACTGTIIQAQPPIIRFVENVQHQEVIHQIEVNHEKVPTIHSSANNYTILNTATVTIENDSINGEQPSSVSGPKLDSVQIGEATAEAPQKSNQISVNHERTKKRKHLTKSPTAKPVTPKTKKDFIYECDICDSRFLAVTSLKLHKTGHRYVSVEEKKAFCCRFCGRQFSHMQTLGDHEKVHIDDRYNCGACGTKYSSKSGLRNHLAKNGECDAHYQQSKLQRKRQDEEFKEHECEICGKKYRHRKSMLEHRSLHFRNKQHKCERCGAMFETSGGWRKHTTNGRCEFSKSKFKDPGGSDEVFIPEERKKFLEQMQETKKKERRTEIIKKRKSRLKENVKNSSSDNEDESVSFGTDHNESSGEEEVSPNPTIELVTVPEISSKIVPESKEEVQDEQEIAIDSIDVDFEIKEEVPSDEEATSLQKAKDEKEQSDVQLSENECFNQNEQSAEIEDESHKDDKQLESQPTEDVLGDGQPKLKPPRGHKNSKNYECPTCHKSFSRKFVLTNHLRTHTGERPYLCDSCPKSFGDAASLKMHVVIHTGEKPFQCSECPARFARKSGLRNHITLHFNLPCDECDQKFPSRKTLMRHKIKHQGVRPFLCEICSKDFRTKADMKAHMRIHSNEKRYSCKICSARFNCPSTLRRHRNVHAPPETRPVCETCGKPFSSQQALRKHENIHKDLKPFQCYICFKRFRVKDHLKIHQRSHSGEKPFSCDVCEKRFVTNGDLKVHYRRHTGEKPFSCEECGQAFVVTAGLYRHQQQTGHKSGKPQAIIVAEYTRAT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -