Basic Information

Insect: Toxorhynchites rutilus
Gene Symbol: -
Assembly: GCA_029784135.1
Location: CM056649.1:21219509-21235942[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.31 35 6.7 3.6 1 23 46 69 46 69 0.86

2 20 0.0077 0.88 11.8 0.4 2 23 87 109 86 109 0.91

3 20 0.024 2.8 10.2 0.1 2 23 133 155 132 155 0.93

4 20 1.1e-06 0.00012 23.9 0.3 1 23 161 183 161 183 0.99

5 20 0.0015 0.17 14.0 0.1 1 20 188 207 188 209 0.93

6 20 0.00036 0.041 16.0 0.5 3 23 220 241 218 241 0.92

7 20 0.0016 0.19 13.9 3.3 1 23 246 268 246 268 0.96

8 20 0.0013 0.15 14.2 2.4 1 23 272 295 272 295 0.97

9 20 5.1e-06 0.00058 21.8 0.7 1 23 537 560 537 560 0.96

10 20 0.0031 0.35 13.0 1.2 1 23 576 599 576 599 0.95

11 20 0.036 4.1 9.7 1.0 2 19 610 627 609 630 0.92

12 20 9.5e-05 0.011 17.8 1.4 1 23 641 663 641 663 0.98

13 20 0.003 0.34 13.0 0.2 2 23 670 692 669 692 0.96

14 20 1.3e-05 0.0015 20.5 0.2 1 23 697 719 697 719 0.98

15 20 2.7e-05 0.0031 19.5 1.9 1 23 725 748 725 748 0.97

16 20 0.0042 0.48 12.6 2.9 2 23 763 784 762 784 0.97

17 20 0.0013 0.15 14.2 0.7 1 23 790 812 790 812 0.98

18 20 0.56 64 5.9 1.5 1 23 818 841 818 841 0.91

19 20 0.00063 0.071 15.2 0.2 1 23 853 875 853 875 0.95

20 20 0.0024 0.27 13.4 2.5 2 23 882 903 881 904 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.31	35	6.7	3.6	1	23	46	69	46	69	0.86
2	20	0.0077	0.88	11.8	0.4	2	23	87	109	86	109	0.91
3	20	0.024	2.8	10.2	0.1	2	23	133	155	132	155	0.93
4	20	1.1e-06	0.00012	23.9	0.3	1	23	161	183	161	183	0.99
5	20	0.0015	0.17	14.0	0.1	1	20	188	207	188	209	0.93
6	20	0.00036	0.041	16.0	0.5	3	23	220	241	218	241	0.92
7	20	0.0016	0.19	13.9	3.3	1	23	246	268	246	268	0.96
8	20	0.0013	0.15	14.2	2.4	1	23	272	295	272	295	0.97
9	20	5.1e-06	0.00058	21.8	0.7	1	23	537	560	537	560	0.96
10	20	0.0031	0.35	13.0	1.2	1	23	576	599	576	599	0.95
11	20	0.036	4.1	9.7	1.0	2	19	610	627	609	630	0.92
12	20	9.5e-05	0.011	17.8	1.4	1	23	641	663	641	663	0.98
13	20	0.003	0.34	13.0	0.2	2	23	670	692	669	692	0.96
14	20	1.3e-05	0.0015	20.5	0.2	1	23	697	719	697	719	0.98
15	20	2.7e-05	0.0031	19.5	1.9	1	23	725	748	725	748	0.97
16	20	0.0042	0.48	12.6	2.9	2	23	763	784	762	784	0.97
17	20	0.0013	0.15	14.2	0.7	1	23	790	812	790	812	0.98
18	20	0.56	64	5.9	1.5	1	23	818	841	818	841	0.91
19	20	0.00063	0.071	15.2	0.2	1	23	853	875	853	875	0.95
20	20	0.0024	0.27	13.4	2.5	2	23	882	903	881	904	0.94

Sequence Information

Coding Sequence: ATGAGTGTATCTAATCCTGACGATAGCTGGAGCACTGGGAGAAATAGATCTGTTCCGAGTGATGAACCCAATGAAGATGCAGAATCGGTGGACGAAGCATTTGAAATCGTCTTTGAAGAGAAGGGTTCGAAATTGTTCTCATGCAAACAGTGTAGAAAGCGGTTCCGCTCGGAGACGCTTTGTATGCGTCACAGAGCTGCAGAACACAATGGGAAGATCCGGTCACATTTGAAACGACACAACAATGAGCGGAAACTGGAATGTGAAGCATGCGGAGCATGCTTTCGACGAATTGAAACTCTCAATAAGCATTGGCTTGCCAAGCATGGTTCACCACAAATTGAGAATGAACATATTAATAAATCCACCGGTACCGAATCTAAGAAGGATACCCTTTCCTGTGGCATGTGTGATGCGGTTTTCAAAAGTCGAGAAGGCAGACGAATTCATATGATTTTGAAACACAATGCCGGCAAGACGTACAAATGTGAGGAGTGTCCGATGATTTTTGCCCGGAAGGGGAACCTGCGTTTGCATATGACAACCCATGGGGTACGACTGCACGTGTGCAGTGTTTGTGGGAGATCCTACGCACGGATTGAAAGCTTGCGGAATCACGAACAGGCCTGCGCGGAGGGAAGCAACGGGGGGCTGTTTTGTGAGGTTTGCGGTCAGCGGTTTCGGAAGCAAGAACTGCTGGAAAAGCACAAATTGCAGGGTCACTCGGAGAAGGAGTATCTGTGTAATCATTGTAGCCAAGGATTCGAGACAAAGCGAGCGCTAAGTCATCACGTGCGGGTTCACGAAGGGACATTTCAGTGCGAGCACTGTTCGCTTAAATTTGTCACGGAGAACGCGCTGAAGAATCATGAGAAGAGTCGGCATTGGGAGATTCTGGGAATCGAACGTAAACAGGGCAGGCAAGGAAAGCGGAGAGATGCTATGGAGGGAACAAAAGAGCCGAAGGTGAGGGTGAGAAGGAACAAATATAATCCATTCATCGGAATGGAACATTTAGCGGCGCAATCGGAGAAGACCGGGGATGTTGAGAAGAAATCCGAGGGCATCAGTGATCAATCAGTTAATATTTGTACAAAGGAAGGCACGTCCAGAAGTACATTCGAAACAGTACCTGACAAACCAGAAACGTTAGAATCAAACCTAGATTCAACTTTTCAGGAGGATGACGATAGAATTCCTAACAACAAACCGACTGACGAAAAGCTTGAAATTGAAAACTTGTCTAGGTTACATTCGAATCTTGAGTACACAATTACTGCACCATCGAAAAGTGGAATTGAAGTGGAGACCCCTGGCGCTATATTAAGCCATGAGCAGGATAATGTCCAACAGCGGGATACCATAACAATTTCCTCGCATGAAGTATATTTGAAGGAAACATTTAATGAATCAGAATCATCCGACTGCACCATTGATAGTGTGGACGGGCATCGTGATGATCCAGATTCGCCCAATGATGAGGGAGATGGCGATGAGGGGAGTTCACAAAATGCTCTGACGCCAATTGAAGAAAAACCAAAAGGCCGACGGAAACGAACAACGTCAAACGGTGACAAACGCGTGGCGGAGAAACCCTTCCCGAAAAAGTATCGCTGCGAAGATTGCGGCAAAACATTTGCCCATCGACCCTGGCTAACATCGCACCGGGCGAAGGCACACGGGATTGAGGAAAAGGATGTTCCACCGCCCAAGAAGAATCGCATTCATTTCTGTGATAAGTGCAACGCAAGTTTGAGCGATTGGCGCAATCTGCTTTATCACCTGAGAAACGTTCACAACGAGACAATCAATGAGGATGATTTGACCAAGTGTGATACTTGCAAGAAGAGATTCATCAGTGCGGAAGGGCTGAAGGGACATTCCTGCGTGAAGGGCATCTATTTGAATCGAAAGGCTCACTACAAGTGTGAGCTGTGCGGGAAAGCTTACTACAGTCAGCATGGTTTGGACAGACATCGTTCGGTGCATCCGGAGAATCATAAAGTGAAATGTGACATCTGTGAGAAGCCTTTCGCCGACGAGAAGGATGTGAAATATCACAAAAAGCGAGTGCACGTGGATGCTAGGTTTGTTTGCGATGTGTGCGGGAAGTCGTTCAAGCTGCTAACTCAGTTGAGGATACACGTTCAAGTGCATCAGGAGCTGAAGCGTCATCAGTGCGAGTTCTGTGGGAAGTCATTTTCACAGCGCAATGGAATGACTACTCACCTGAAGATAGCACATGCCGAACAGCTTGGAGAGCAAGCGATGGCGGAGCGGGAGCTGACGTGTGAGATTTGTGACAAAAAACTGAAGGGAAAAGTGTGCTACAAACTTCACATGAAGACTCACACGAATGAGCGCAACTTCCCTTGCTCGTACTGTGACAGGTCATTCGTGGCGAAACAGGACAAAATTCGGCACGAGCAAACACATACGAAAAACTATCGGTTCAAGTGTCGTTTCTGCGATAAGGGATCGACCAGAAGGAAGTTGATATTGTTGCACGAGGCTAAGAAGCACAACTATGTTAGTGCGGAATCGATTGGTCCGTCGCACAAATGCTCCATCTGTGGCAAAAGCATGAGCTCACCGTCCGCACTGGCAATCCACGAATCGCTTCACAGCGACGACCTCACGGTGAAGTGTGAGCAGTGCGATAAGATGTTTAAAAATGTGAAATATATGAAATATCATTTGAATGCTCATCATCTAAAAAAGGTGGGTAGCGTCAAGGGGTCCAGGAATAGAAAAGCTGATGACTTACAGAATCTACAGACAGTCGAGAGTGTGCAGCATCAGGATCAAACGAGTGAACGCTTGAGCGAAGGTGTGAGGTGA
Protein Sequence: MSVSNPDDSWSTGRNRSVPSDEPNEDAESVDEAFEIVFEEKGSKLFSCKQCRKRFRSETLCMRHRAAEHNGKIRSHLKRHNNERKLECEACGACFRRIETLNKHWLAKHGSPQIENEHINKSTGTESKKDTLSCGMCDAVFKSREGRRIHMILKHNAGKTYKCEECPMIFARKGNLRLHMTTHGVRLHVCSVCGRSYARIESLRNHEQACAEGSNGGLFCEVCGQRFRKQELLEKHKLQGHSEKEYLCNHCSQGFETKRALSHHVRVHEGTFQCEHCSLKFVTENALKNHEKSRHWEILGIERKQGRQGKRRDAMEGTKEPKVRVRRNKYNPFIGMEHLAAQSEKTGDVEKKSEGISDQSVNICTKEGTSRSTFETVPDKPETLESNLDSTFQEDDDRIPNNKPTDEKLEIENLSRLHSNLEYTITAPSKSGIEVETPGAILSHEQDNVQQRDTITISSHEVYLKETFNESESSDCTIDSVDGHRDDPDSPNDEGDGDEGSSQNALTPIEEKPKGRRKRTTSNGDKRVAEKPFPKKYRCEDCGKTFAHRPWLTSHRAKAHGIEEKDVPPPKKNRIHFCDKCNASLSDWRNLLYHLRNVHNETINEDDLTKCDTCKKRFISAEGLKGHSCVKGIYLNRKAHYKCELCGKAYYSQHGLDRHRSVHPENHKVKCDICEKPFADEKDVKYHKKRVHVDARFVCDVCGKSFKLLTQLRIHVQVHQELKRHQCEFCGKSFSQRNGMTTHLKIAHAEQLGEQAMAERELTCEICDKKLKGKVCYKLHMKTHTNERNFPCSYCDRSFVAKQDKIRHEQTHTKNYRFKCRFCDKGSTRRKLILLHEAKKHNYVSAESIGPSHKCSICGKSMSSPSALAIHESLHSDDLTVKCEQCDKMFKNVKYMKYHLNAHHLKKVGSVKGSRNRKADDLQNLQTVESVQHQDQTSERLSEGVR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -