Basic Information

Insect: Toxonevra muliebris
Gene Symbol: zfh1
Assembly: GCA_963691655.1
Location: OY829327.1:97680932-97686092[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.23 18 6.7 0.2 1 23 25 48 25 48 0.94

2 14 0.00035 0.028 15.5 0.1 1 23 427 450 427 450 0.96

3 14 0.0045 0.36 12.0 1.6 1 23 456 478 456 478 0.98

4 14 0.00022 0.017 16.2 0.5 1 23 484 507 484 507 0.94

5 14 6e-05 0.0048 17.9 0.3 1 23 513 535 513 535 0.96

6 14 0.0036 0.29 12.3 4.1 1 23 541 563 541 563 0.98

7 14 2.5 2e+02 3.4 1.2 5 23 583 602 569 602 0.75

8 14 0.31 25 6.2 4.6 2 23 927 949 926 949 0.93

9 14 1.4e-05 0.0011 19.9 0.2 1 23 956 979 956 979 0.97

10 14 0.0037 0.3 12.3 3.3 3 23 987 1007 985 1007 0.98

11 14 0.00014 0.011 16.8 1.3 1 23 1013 1036 1013 1036 0.92

12 14 6e-05 0.0048 17.9 0.3 1 23 1042 1064 1042 1064 0.96

13 14 0.0036 0.29 12.3 4.1 1 23 1070 1092 1070 1092 0.98

14 14 0.0084 0.67 11.2 1.9 1 23 1098 1121 1098 1121 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.23	18	6.7	0.2	1	23	25	48	25	48	0.94
2	14	0.00035	0.028	15.5	0.1	1	23	427	450	427	450	0.96
3	14	0.0045	0.36	12.0	1.6	1	23	456	478	456	478	0.98
4	14	0.00022	0.017	16.2	0.5	1	23	484	507	484	507	0.94
5	14	6e-05	0.0048	17.9	0.3	1	23	513	535	513	535	0.96
6	14	0.0036	0.29	12.3	4.1	1	23	541	563	541	563	0.98
7	14	2.5	2e+02	3.4	1.2	5	23	583	602	569	602	0.75
8	14	0.31	25	6.2	4.6	2	23	927	949	926	949	0.93
9	14	1.4e-05	0.0011	19.9	0.2	1	23	956	979	956	979	0.97
10	14	0.0037	0.3	12.3	3.3	3	23	987	1007	985	1007	0.98
11	14	0.00014	0.011	16.8	1.3	1	23	1013	1036	1013	1036	0.92
12	14	6e-05	0.0048	17.9	0.3	1	23	1042	1064	1042	1064	0.96
13	14	0.0036	0.29	12.3	4.1	1	23	1070	1092	1070	1092	0.98
14	14	0.0084	0.67	11.2	1.9	1	23	1098	1121	1098	1121	0.96

Sequence Information

Coding Sequence: ATGAGTAACGAGACGGAATCACTGCACATATGTGGGAACATATTAAGTACGAAAAATTACAGTATCTTTACATTCCGCTGCACGGATTGCGCTGACAGCTTCGGTCAATGGTTAGCATTCATCAAACATTTAGAACTAAAACACGGTGGTGGAAACGATGATAGTCTTAGAAATTCTGTAAAATGTGAATTTGTTGATGAAGAATTTATTGAGGAAGgtggtattaaaaattcactgGAGAATGTATGGGAAGGTGAAGATCTTCATGAACTTAGTAGTAGCGAAAACAAAGATGACGATGAAGTGGAAATAGATTATCCAGAATCCGATTCTCAAAAGgaTGAAGAAAAACCTGCCAAAGCAATAACAAACCAAGGAGATAAGTCAAAGCAGGAGGATGAACAATTGAAAACGttttattttgatatacGTGATGCTGAGTCTAAAAAACTTGCACtggaatttctaaaaatattggaAGAAAATTCATTACTTTGGGATTACAAGCATAAAGACTATCGTAAAACACGATCAAGAGCAAAAGTATTTCCACGAatgaaattgcatttaaaaaaaatgggatacACTGTCGAAGATTCGACATTACTCCGAATAATAACAGACATTTTACGCGATTACCGTAAAGCTAAAGAAGAGTTTGCTCTCCAGCGAAAATTGGATAAACGTTTACAATTTCTATTGAATAAATGCAAGTTTTTAGATGAACCCGACGTTGGCTTTAAAATGGACACTGTAATTAACGACAATGATGCAGAAACCGAAGATgaAAGCGACTCAGATAGCTCGGAAAATGCTGTTAAAAATCCAGAACTAGCAAAAATTCTTATATGCAAACCTAATGGTCGCTTTAAACGATTGCGTTTCCATGTTGCTTCCAATAAACTAGCCATCGATCTCATAGAGCTATGGCGAGAGAACCCACTTCTATGGGACACAAACCTTCAGGGTCATAACAATATAAACCATCGTAAGCGTATAATCATGTCATGGATTCCTATTTATAAAGAGCGACATGATGTAATGTTTACCTATGAGGACctttctgaaaatttaaaattattacgtCGTTACTACAATAAGCTAAATACGCGTAAAGTAATGAATGAAgcagcaaaatatataaaagaaaaatgcagcTTTCTAcctaaatcaaacaaatttggAAAGATTAAATGTGACCATTGTAACAGTTTCTGTCTCACCGAAATCAATTACAAGGCGCATTTGTATAATGAACATCAAATTGGGGAGAACCCATTCAAATGTGAGGAATGTGGTAAAACATttcccattgcgtttaagcttGATGCGCACGTACAATCAATACATAAAAAGGAGTTTAATTTTAGTTGTACGGTGTGCGATAAACAATTTCTTCAGAAATGTGTTTTGGCAGCTCATATGAGATTACATACGGGAGAGAAAACGTTTGTTTGTGAAACGTGTGGCAAAAGTTTTCGGCGAATAGACCTGATGAAAATGCATGAAACACGAATACATTTGCGACAACGTAATTTCCCTTGTACTATGTGCCCGAAAGCATTCTACACAAAACAGTTACTGAAGGATCATGTCAATGCGCATTTGGATATACGTAATTTTAAATGCCCTTTTTGCGATAAAGCATTCCACAGTGCACACGCTAGAATGCGCCATAAACAAATCCATTCCGAGGTGAAGCGATATGCGTGCAAATTATGTGATGCAAAGTTTCATCAATTTGTTGATTGCGGAGACAGCTTTGACCAATGGCTAGAATTCATCAAACATTTGGAACTAAAACACAGCGGTGGAAACGATGACAGCCTGAGAGATTTAGTAAAATGTGAATTTAGTGATGAAGAATTGATTGAAgaagaaagtataaaaaatgaacTGGAAAGCGTGTGGGAAGGCGAAAATCTTCAAGAGTTTGGTAGTAGCGAAATCAAAGACGAATCTGAAATGGAAGTAGATAATGCAGAATCGGATTCTCAAGAGttttattttaatatacatgATGCTGAATCTAAACAAATTTCATTGGAATTCCTAAAAATATTAGAAGAAAATTCATTACTTTGGGATTATAAGCATAAAGATTATCGAAAAATACGAGCAAGGGCAAAATTATTTCCACAAATGAAATTGCATTTAAAGAAAATGGGGTACACTGTCGAAGATTCGGCATTGCTCCGAATAACAACAGAAATATTACGAGATTACCGTAAAGCTAAAGAAGAGTTTGCACTCCAGCGAAAATTGGATAAACGTTTACAATTTCTATTGAATAAATGCAAGTTTTTAGATGAACCCGATATTGGCTCTAAAATGGGCACTGTAATTAACGACAATGATGCAGAAACCGAAGATgaAAGCGATTCGGATAGCTCGGAAAATGCTGTTGAAAATCCAGAATTAGCAAAAATTCTTATATGCAAACCTAATGGTCGCTTTAAACGATTGCGTTTTCATGTTGCTTCCAATAAACTAGTCATAGATCTCATAGAGCTATGGCGAGAGAACCCACTTCTATGGGACACAAACCTTCAGGGTCATAACAATATAAACCATCGTAAGCGTATAATCATGTCATGGATTCCTATTTATAAAGAGCGACATGATGTAACGTTCACCTATGAagattttgttgaaaacttaaaattattacgTCTTTACTACAATAAGCTTAATACGCGTAAAGTGATAGATGAAgcagcaaaatatataaaagagaaaTGCAGCTTTCTATCTAAATCAAAGAAATGTGGAAAGATAAAATGTGACCATTGCAATAGTTTCTGTCGCACTGAAACCAATTACAAGGCGCATTTATATAATGAACATCAAATTGGGGAGAGCCCATTTAAATGTGAGGAATGTGGCAAAACATATCCCAATGCTTCGAAACTTGATACTCACGTGCAATCAatacacaaaaagaaatttgattttggcTGTACGGTATGCGATAAACGATTTCTTCAGAAATGCCTTTTAACAACACATATGAGATTACATACGGGAGAGAAAACGTTTGTTTGTGAAACTTGTGGGAAGGGTTTTCGACGTATTGATCATTTCAAAAATCATGAAGTACGCATACATTTGCGACAACGTAATTTCCCCTGTACTATGTGCCCGAAAGCATTCTACACAAAACAGTTACTGAAGGATCATGTCAATGCGCATTTGGATATACGTAATTTTAAATGTCCATTTTGTGATAAAGCATTCCACAGTGCACACGCTAGAATGCGCCATAAACAAATCCATTCCGAGGTAAAGCGATATGCGTGCAAATTATGTGATGCAAAGTTTCATCAATTTGTTGGTTTGAATTCGCACATGAAGAATCGTCATAGCACCGAATAA
Protein Sequence: MSNETESLHICGNILSTKNYSIFTFRCTDCADSFGQWLAFIKHLELKHGGGNDDSLRNSVKCEFVDEEFIEEGGIKNSLENVWEGEDLHELSSSENKDDDEVEIDYPESDSQKDEEKPAKAITNQGDKSKQEDEQLKTFYFDIRDAESKKLALEFLKILEENSLLWDYKHKDYRKTRSRAKVFPRMKLHLKKMGYTVEDSTLLRIITDILRDYRKAKEEFALQRKLDKRLQFLLNKCKFLDEPDVGFKMDTVINDNDAETEDESDSDSSENAVKNPELAKILICKPNGRFKRLRFHVASNKLAIDLIELWRENPLLWDTNLQGHNNINHRKRIIMSWIPIYKERHDVMFTYEDLSENLKLLRRYYNKLNTRKVMNEAAKYIKEKCSFLPKSNKFGKIKCDHCNSFCLTEINYKAHLYNEHQIGENPFKCEECGKTFPIAFKLDAHVQSIHKKEFNFSCTVCDKQFLQKCVLAAHMRLHTGEKTFVCETCGKSFRRIDLMKMHETRIHLRQRNFPCTMCPKAFYTKQLLKDHVNAHLDIRNFKCPFCDKAFHSAHARMRHKQIHSEVKRYACKLCDAKFHQFVDCGDSFDQWLEFIKHLELKHSGGNDDSLRDLVKCEFSDEELIEEESIKNELESVWEGENLQEFGSSEIKDESEMEVDNAESDSQEFYFNIHDAESKQISLEFLKILEENSLLWDYKHKDYRKIRARAKLFPQMKLHLKKMGYTVEDSALLRITTEILRDYRKAKEEFALQRKLDKRLQFLLNKCKFLDEPDIGSKMGTVINDNDAETEDESDSDSSENAVENPELAKILICKPNGRFKRLRFHVASNKLVIDLIELWRENPLLWDTNLQGHNNINHRKRIIMSWIPIYKERHDVTFTYEDFVENLKLLRLYYNKLNTRKVIDEAAKYIKEKCSFLSKSKKCGKIKCDHCNSFCRTETNYKAHLYNEHQIGESPFKCEECGKTYPNASKLDTHVQSIHKKKFDFGCTVCDKRFLQKCLLTTHMRLHTGEKTFVCETCGKGFRRIDHFKNHEVRIHLRQRNFPCTMCPKAFYTKQLLKDHVNAHLDIRNFKCPFCDKAFHSAHARMRHKQIHSEVKRYACKLCDAKFHQFVGLNSHMKNRHSTE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -