Tmul001254.1
Basic Information
- Insect
- Toxonevra muliebris
- Gene Symbol
- -
- Assembly
- GCA_963691655.1
- Location
- OY829326.1:6455902-6458388[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.029 2.3 9.5 5.2 2 23 279 300 278 300 0.96 2 12 0.28 23 6.3 3.1 1 23 306 331 306 331 0.93 3 12 0.00072 0.057 14.5 0.1 1 23 338 363 338 363 0.97 4 12 0.00035 0.028 15.5 2.0 1 23 375 397 375 397 0.98 5 12 3.2e-06 0.00026 21.9 0.2 1 23 404 426 404 426 0.98 6 12 0.0053 0.43 11.8 0.1 1 23 432 454 432 454 0.98 7 12 0.024 1.9 9.7 4.9 1 23 460 483 460 483 0.97 8 12 0.011 0.88 10.8 2.4 1 23 489 511 489 511 0.95 9 12 0.00045 0.036 15.2 2.8 2 23 518 539 517 539 0.96 10 12 2.5e-06 0.0002 22.2 0.5 1 23 643 666 643 666 0.96 11 12 0.012 1 10.6 5.7 1 23 672 694 672 694 0.97 12 12 8.3e-07 6.7e-05 23.8 1.5 1 23 700 722 700 722 0.96
Sequence Information
- Coding Sequence
- ATGGAAGGCGGGAGTCAATACAGCATTCACTCTATTTGCCGCATATGCTTGGAGTATTTGCAGAATGAGAGCGCTTACGACCTCTTTATTATACCAGGTTTGGCGAAGAAGTTGATCGTATGTACATCTTTGTCGGTGGAGCCGCAAGATGGATTCCCTAAGAACATTTGCGGAGTTTGTTATACCCGTCTCAACGATTTAcacgaatttcaaaaattatgtgtAGACTCTGTGCAAAAGTTTCAGGATATGGTAACAAATAACACGTTTAGCGGTCCAGTGAACGCTTTTGATGTACTGGAGGCGGATGCTGTGGATGCGCAAAATGCTGCAGCTAATGAAGATGATGAACgtctaaattttgatccacTGTTAAATCATAAAATGGAATTGATTGAAAACGAGGAGGATGTATTTAAAATGCTGGAGCATGTCGGCAAAGAGGTAGATGAGGAGGGGGCACCACAAAAGGAGGAGTTTGAAGTGGAACAGCAAGAAAAATCTTTCAATGAGAAAGACTTTTTCAGCAGCGATTCATCAACCAGCGTGTCCGATAACGATAATGACTTCGCACCAGATTTAGGAAAGTATGATAATGATGCTGATAGCGAAAAAGAGGAGAAAGTAGAAGTAGAGAAGGAAGATAACAGCGAAAGTGATGACGACAAACCATTGGCGTTACGGTTACGGTTGCGTAAACGAGTTCCAAGGCTTccaattaaagaagaaaattccgACGGTGAGCCAATAGAAGATAAGGATAAGGGAGAAACTAAGCCCAAACCGAAACGTAAAAGAATACCAGCCACCGAACGTCATTTACATCGCATAATTGAGTGTCATATTTGccacaaaaaattcaagaaagtaGAGCGTTATGATAGCCATATGAAATACCATAACGATAAGCTGCCACACCAGTGTACTGTCGCAACATGTCTGAAAGGTTTCACTACAGCAAATGGACTTCGTCTACACGTAGAGCATTGCCACGCCGACACACTTGAGAGTTTCCCTTGTCCGGAAGAGGGCTGCGGACGTTTATTCCCTCGTACCCGCCTGCTAAACTGGCATCTGAAAAAGGTGCACAAAATTGTAAAGGAGCTAAACGAACCTAAGTGCTATCCATGCACCGAATGCGAGAAAGTTTTCCGTTGTCCAATGGCTCTCAAGAAACACATGTATAAGCACGACGGCAAGGAACTACCATTCCCCTGCAACATTTGCGGAAAACGATTCGTTATTAACAGCGCTCTCAAGGATCATCTAATGCGTCATGCAGGCATCAAGAACTACGTATGTCCATACTGTGGTGTCGGCAAGACTACACGTCAGGAGTGGAACACtcacataaatacacatacacaagaAAAAAAGTTCAAGTGTCATTTGTGCCCTCATGCCTCACACAACAAGCAAAATCTTCGGATGCATGTAAAAATTGTGCATGAAAAGATCAAGGACTACGCCTGTCAGTACTGTGGCAAAACTTTTGGCAAATCGAATGCATGCAAAATGCACGAAATGACACATACCGGTGAGAAGCGGTGCGAATGTAAGGTGTGCGGCAAGCGTTTTCTGTACGCTAAAGGCTTAACGAAACATCTGAAGACACATGAAAAACGTGTGCTGCGTGCAATAGAGGTTTATCGTAAGCGGCAGATAGAAGGAGGTGCTACTGAAGAACAGCCTCCGCCAATACCAGAATTACCGGAACCGGAGAATCACTCAAGAGAGACTCATCAAAAGGTTGCCGATGAAATATTGAAGGTATGTGCCGAGTCAGCGGCCTCCATTCCAAAAGATCCACGGCGTGTCGAACGAGTAGATATTGCGCAACTAGCTGGTACTGCTGTTAATCCGATACCTTCTGTAGCGGTGCCATCGTGGTCGCCACAAATCAACTTTATGATGAAAGAAGGACCGCACATTTGCCCTGATTGTGGACAGGGCTTCAACGGGCCTGGAAATTTGAAACGGCATCATCGTATCGTACACGAAGGAGTCAAGGACTTTGCTTGTCGCTTCTGCCACCGTCGTTTTGCCAAAGCGCAAACACTCAAACATCACGAAATGACCCACACCGGAGAAAAGCCACATGCATGCAAAAATTGCGGCAAGAGTTTCATTCAATATGTCGCTCTTAAACGACACATGAAGGTGCACATGAATAAACCACCGCCCGTGATTCCGGCAAGTGTATATCACGCTAGGGAAGAGCTTCAACTGCAAGAACGCCAAAAATTGGAGGCCAAACGTAAAGCTCAAGAAGCGAAAGCAGCTATTGCTGAGGCCGCCAGAGAGcaattaaatgaaatgcaaCTGCAGCAGGAAGAAATACAAAAAGGACAAGATGAAAGTGATGGTTTGATAGCTGATGGTGGTGATATTGCCACAACCAGTAGCAATTCAGGTCTTGGTGATTTCCCTCATATAAATACAAGCACCATGGGTATTCGCACTGTCGGCGTCAATGATGCATCATAA
- Protein Sequence
- MEGGSQYSIHSICRICLEYLQNESAYDLFIIPGLAKKLIVCTSLSVEPQDGFPKNICGVCYTRLNDLHEFQKLCVDSVQKFQDMVTNNTFSGPVNAFDVLEADAVDAQNAAANEDDERLNFDPLLNHKMELIENEEDVFKMLEHVGKEVDEEGAPQKEEFEVEQQEKSFNEKDFFSSDSSTSVSDNDNDFAPDLGKYDNDADSEKEEKVEVEKEDNSESDDDKPLALRLRLRKRVPRLPIKEENSDGEPIEDKDKGETKPKPKRKRIPATERHLHRIIECHICHKKFKKVERYDSHMKYHNDKLPHQCTVATCLKGFTTANGLRLHVEHCHADTLESFPCPEEGCGRLFPRTRLLNWHLKKVHKIVKELNEPKCYPCTECEKVFRCPMALKKHMYKHDGKELPFPCNICGKRFVINSALKDHLMRHAGIKNYVCPYCGVGKTTRQEWNTHINTHTQEKKFKCHLCPHASHNKQNLRMHVKIVHEKIKDYACQYCGKTFGKSNACKMHEMTHTGEKRCECKVCGKRFLYAKGLTKHLKTHEKRVLRAIEVYRKRQIEGGATEEQPPPIPELPEPENHSRETHQKVADEILKVCAESAASIPKDPRRVERVDIAQLAGTAVNPIPSVAVPSWSPQINFMMKEGPHICPDCGQGFNGPGNLKRHHRIVHEGVKDFACRFCHRRFAKAQTLKHHEMTHTGEKPHACKNCGKSFIQYVALKRHMKVHMNKPPPVIPASVYHAREELQLQERQKLEAKRKAQEAKAAIAEAAREQLNEMQLQQEEIQKGQDESDGLIADGGDIATTSSNSGLGDFPHINTSTMGIRTVGVNDAS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01133104;
- 90% Identity
- iTF_01133104;
- 80% Identity
- -