Basic Information

Gene Symbol
-
Assembly
GCA_036873485.1
Location
JAYJLV010000027.1:12288502-12289676[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.00098 0.26 13.8 0.1 3 23 83 104 81 104 0.95
2 9 0.001 0.27 13.7 2.1 1 23 108 130 108 130 0.99
3 9 0.089 23 7.6 4.0 1 23 136 159 136 159 0.90
4 9 9.7e-05 0.025 16.9 1.1 2 23 167 189 166 189 0.95
5 9 4.3 1.1e+03 2.3 0.3 3 13 196 206 194 215 0.77
6 9 8.4e-06 0.0022 20.3 1.7 1 23 226 248 226 248 0.98
7 9 3e-05 0.0078 18.5 0.2 1 23 252 274 252 274 0.98
8 9 6.5e-06 0.0017 20.6 0.6 2 23 279 300 278 300 0.97
9 9 1.9e-06 0.00051 22.3 6.7 1 23 306 328 306 328 0.99

Sequence Information

Coding Sequence
ATGCGAACTAACACaaatttttctaCTCCTTCCTACTCTACGTATAAGAACGGCACTACCACCAACGGTGTTTCTtctgttgctgctactactactaccaacGGCACTACCACCAATAGTATTATTATCAGCACCAATGGTACAacttctactgctgctactgcaaaTGGTAAAAGCTCGCGCACACGTCGACGTCCAAGCTGGCTAAAAGACACAGTGACTGATTTTGATGCTCTCCGCGACATCTGTCCCTACTGCGACCGTCGCTTCGAGGACGAGTACAGAGTGGCTCAACACGTGCGCAATGCTCACAAGAAGCCCTTCAAGTGCGACCTTTGCCGTCGTCAGTATTTCAGTCAGGAGGTGCTTGCGCGTCACCGCAAGACCCACAACACCGATTCACACTTCGAGTGCAGTATCTGCCATCTGAAGTACAAAAGGGAGGAGACACTCCAGTGTCATTACGTGCGCGTGCACAGCGACATCGAAGCCTCGATCACGTGCGATCATTGCGGCAAGAAGTACAAGCTGAAGCAGGACCTGCTGCTGCACATCAATCAGGTGCACATGTGCAGCTACCAGATCTGCCGGTTCTGCGGCAAGGCTGTAAAGAACGTGAAGGCGCACGAATGGCATCACCAACAAAAGCTCGAGCACGTGAAGAAGGAGATCAGATATCCGTGCAGCCTCTGCTTCAAGAAATTCCGCAGCGAGTCCAAGCTTGAGAACCATCTGATGCGTCACGTGCAGCGCTACAAGTGCTCGACCTGCGGTGAGAATTTCCCGGGTCCCGGGCAGCTGATGAATCACAAGTCGAAGCACAGGCCTGGCGTCACCTGCACCATCTGTGACAAGTTCTTCGCATCGCGCAGCAACTATTATCAGCACGTGCTGATGCACGCCAAGGTACGGCCGTACAAGTGCGACGTCTGCCACGAGTGCTTTACTCAGCGCTCAACATTGGTGCGCCACAGGAAGACCCATCCGGGTCCGATGCCCACGGAGATAAAGGTGGTTCCGATCGCCAATTTGGCCAGGAAGGTCCTGGAGAACTGGTCCTAA
Protein Sequence
MRTNTNFSTPSYSTYKNGTTTNGVSSVAATTTTNGTTTNSIIISTNGTTSTAATANGKSSRTRRRPSWLKDTVTDFDALRDICPYCDRRFEDEYRVAQHVRNAHKKPFKCDLCRRQYFSQEVLARHRKTHNTDSHFECSICHLKYKREETLQCHYVRVHSDIEASITCDHCGKKYKLKQDLLLHINQVHMCSYQICRFCGKAVKNVKAHEWHHQQKLEHVKKEIRYPCSLCFKKFRSESKLENHLMRHVQRYKCSTCGENFPGPGQLMNHKSKHRPGVTCTICDKFFASRSNYYQHVLMHAKVRPYKCDVCHECFTQRSTLVRHRKTHPGPMPTEIKVVPIANLARKVLENWS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00464170;
90% Identity
iTF_01469966;
80% Identity
-