Basic Information

Gene Symbol
-
Assembly
GCA_030522985.1
Location
JAPYZP010006397.1:5094-8133[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.018 4.2 9.9 0.3 6 21 12 27 6 28 0.86
2 14 0.91 2.1e+02 4.5 0.0 2 21 34 53 33 54 0.91
3 14 0.15 34 7.0 0.2 1 12 229 240 229 249 0.88
4 14 0.092 21 7.7 0.7 1 20 368 387 368 389 0.94
5 14 0.00017 0.039 16.3 0.4 2 23 394 415 394 415 0.98
6 14 0.036 8.2 8.9 2.4 1 23 426 448 426 448 0.95
7 14 0.14 32 7.1 0.2 1 23 467 488 467 488 0.93
8 14 0.0081 1.9 11.0 0.0 2 23 494 515 493 515 0.95
9 14 6.4e-05 0.015 17.6 4.8 1 23 589 611 589 611 0.99
10 14 7.2e-06 0.0016 20.6 4.0 1 23 617 639 617 639 0.96
11 14 0.00017 0.039 16.3 4.6 1 23 645 667 645 667 0.98
12 14 9.1e-06 0.0021 20.3 0.8 1 23 673 695 673 695 0.98
13 14 0.00012 0.028 16.7 0.2 1 23 699 721 699 721 0.99
14 14 0.00013 0.029 16.7 0.2 1 23 729 751 729 751 0.97

Sequence Information

Coding Sequence
ATGGGTTCGATGACCCTGATATGTCCTATGTGCTGTGGAGAGACTTTTAATAATTCGGAGTCTCTCAAGTATCACTTACTGAGTATGACTGATAATTTGTATTGCCCTGGTTGTTCTTTGAGAACATACTCCGTGGCTGCGTTGATACAGCACTTGGATACTTGTGGGAAGGATTCAGAGCAAGAGGAGCTGGAGCAGAGAAATAGTCAAACTGATAGTAAATTAGAAGATAATATTAATGATGATAAAGGGGGACCAGATATTTTAATGGATGATGGTGATGATCCTATGAGCGACAGTTTTTTGGCAACTGTCAATGAAGAAGGTATCATGATTGTTGGAGAAGGCAGGACTATTCAAGTGGATGAAAAtggTGATATTCAAGTTTTAGAGAAGGGTAGTCATTTGCAGGATGAATCTTTTATTACTATCAATGATACAGATAATTCAAATGACAACACCATTAAATCTTCCAAAATTTCTGCTGCAATTCAACATGATCACTCAATGGCAAAAAAacctataataataaatgaatctaATGCTTCGGAATTCCTGAATAGCAACTCTGATTCTCTAATTAATATGTCACAAATTGATGATATTCAAATGGATCATTGTAATAcgcttataaaaaaagaatctgAAATGATACTAGAAAATGACCAGGAAGCAGAAATCATGTACAGCTGCAGTACTTGTGGTTTGAGTTTTAGTTCTGTATTAGAACATATACAAGAGTATCATAATGGACAAGAAGTTATACTAGAAATGGCAGAACAACAATTAGATGAAATAGAAACATCAACAGATGTTGCAATTCCAACTCCAGTTGTTACAAGCCCGTTACCACCGAACAAAATTCTTCAAACGCCTATACAAACAAAACATAGACAGTCTATGAACACTTTAAGAACTGAAGAATGTGTTGATAGTGAAGGTAGACTGTACACAAGGAAAGTTGTACAAATTGAAAGGTTTAGTGATAGAACCCCAGTTACTTTGTCATCTACAAAAGCAccaatgattgaaaaatttttttctaatgttGAGGGAGTTAAggTCAGGGATAAAAGCGTCACCGTTGCCCCAACTCGGATGTATAGGTGCAACCAGTGTCTAGAACAATTTGCAAAATTAGGCGATTTTCGCGTTCACGTGTGCCTTCAAGGGAACAACCGATGCGACCAATGCGAACAAACCTTTGCTACTGTAAAAGCGTTACAATTGCACATGAAAGTTCACGAAAACAGTGAATTTCCTTCACAGAAGATATTCCTCTGCACCGTATGCGGGACCGAATTCTTAACGCACAAAAGTCTACGATTGCACTCGCGGATGCACCTTCCCGTCAAAGCGCGACACGTCGACGCACCCGAAGGCACGGAAGAAGAGACATTCGATTGTAGCGAGTGCGGCACAACGCTGTCGGAATCGTATAGAACAGCGCACATGGCCTTGCACACCGGCGACTCGATCACCTGCGCGGTGTGCAATCGGAAATTTGACTCGGAGGAGAGTTTGGCGATGCACGCGGCAGTGCACACCGAAGCTGCCAACATACAACATGGCTCGCcgaacgcagcagcagcagcagcatccgcCGCGGCGGCGGTAGCGGCGAACGATCTCGTTGCCGCGAGCGGGCAAGATAACGCACAAGAATTGGAATTCATCAGTACGGGTATGACACCGGGGACGACTCCCGGGAACACTGCAACGAACGCGACGCAGGATCCTGTGGAGGTGCAGATACAGAAGCCTTATCAGTGCCAGCACTGCGGGCGGAGGTTCACGCGGCCCCACGAAAAAGTGAAGCACGAAAGGATACATACGGGAGAGAAGCCGCATGCTTGCGAGGTCTGTGGTAAAAAGTTCCGAGTATCCTACTGCCTGACTCTGCACATGCGAACGCACACGGGTGTGCGGCCGTATGAGTGCCAACACTGTGGCAAGCGCTTCAAAGCTTCGTCGGTTTACAACCATCATCTTTTAACCCACGGTGACGAGCGCGCCTACACTTGTCCATTCTGCCCAAAGACCTTCAAGACGCGGGTGCAGCTCGCCGGCCACAAGAACAGCCATACGAAGCCGTTTCGCTGCACCGAGTGCTCGCGGCCGTTCGCCTCGCTCTACGCGGCACGTGCTCACATACAAACTCATCGGAAGGACAACAACCTGAAGTTCAGCTGTAACATCTGCGGAGCATCATACGGCCGTGCATTCGCCCTCAAGGATCACCTCAAGCAGCACGAGGGCGAGACTACGCTGCTATTGCCGCCGGAGCCCGCGCACGAGGAAGAAGTAGTGCAGCAGGTTGATTCTTTCTTTGAGAGTGAGGAACTCATCGTGCCGTCACCGCCACGTGGTGAGCTCATACACACGGTGCTCGACGATGACGAATAA
Protein Sequence
MGSMTLICPMCCGETFNNSESLKYHLLSMTDNLYCPGCSLRTYSVAALIQHLDTCGKDSEQEELEQRNSQTDSKLEDNINDDKGGPDILMDDGDDPMSDSFLATVNEEGIMIVGEGRTIQVDENGDIQVLEKGSHLQDESFITINDTDNSNDNTIKSSKISAAIQHDHSMAKKPIIINESNASEFLNSNSDSLINMSQIDDIQMDHCNTLIKKESEMILENDQEAEIMYSCSTCGLSFSSVLEHIQEYHNGQEVILEMAEQQLDEIETSTDVAIPTPVVTSPLPPNKILQTPIQTKHRQSMNTLRTEECVDSEGRLYTRKVVQIERFSDRTPVTLSSTKAPMIEKFFSNVEGVKVRDKSVTVAPTRMYRCNQCLEQFAKLGDFRVHVCLQGNNRCDQCEQTFATVKALQLHMKVHENSEFPSQKIFLCTVCGTEFLTHKSLRLHSRMHLPVKARHVDAPEGTEEETFDCSECGTTLSESYRTAHMALHTGDSITCAVCNRKFDSEESLAMHAAVHTEAANIQHGSPNAAAAAASAAAAVAANDLVAASGQDNAQELEFISTGMTPGTTPGNTATNATQDPVEVQIQKPYQCQHCGRRFTRPHEKVKHERIHTGEKPHACEVCGKKFRVSYCLTLHMRTHTGVRPYECQHCGKRFKASSVYNHHLLTHGDERAYTCPFCPKTFKTRVQLAGHKNSHTKPFRCTECSRPFASLYAARAHIQTHRKDNNLKFSCNICGASYGRAFALKDHLKQHEGETTLLLPPEPAHEEEVVQQVDSFFESEELIVPSPPRGELIHTVLDDDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01466525;
90% Identity
iTF_01466525;
80% Identity
-