Tyan051242.1
Basic Information
- Insect
- Topomyia yanbarensis
- Gene Symbol
- -
- Assembly
- GCA_030247195.1
- Location
- CM058070.1:140439038-140441431[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.004 0.41 13.2 1.6 2 20 156 174 155 178 0.89 2 17 0.064 6.5 9.4 0.3 1 19 191 209 191 211 0.93 3 17 4.9 5e+02 3.5 0.1 2 23 221 243 220 243 0.94 4 17 0.057 5.8 9.6 3.1 1 23 248 270 248 270 0.98 5 17 1 1e+02 5.6 0.8 1 20 288 307 288 309 0.94 6 17 0.0075 0.76 12.4 0.6 3 23 330 351 329 351 0.94 7 17 0.024 2.4 10.8 0.4 2 21 364 383 363 384 0.95 8 17 0.11 11 8.7 0.2 1 23 391 413 391 413 0.98 9 17 0.071 7.2 9.3 2.6 1 23 419 441 419 441 0.94 10 17 2.9 2.9e+02 4.2 8.1 1 21 458 478 458 479 0.93 11 17 5.3e-06 0.00054 22.3 0.7 1 23 486 508 486 508 0.97 12 17 0.24 24 7.6 2.9 1 12 514 525 514 538 0.88 13 17 7.3e-05 0.0074 18.7 0.8 1 23 542 564 542 564 0.98 14 17 1.1e-05 0.0011 21.2 3.9 1 23 570 592 570 592 0.98 15 17 1.5 1.6e+02 5.1 0.6 1 23 598 620 598 620 0.96 16 17 0.023 2.4 10.8 2.4 1 23 626 648 626 648 0.98 17 17 0.65 66 6.3 5.6 1 23 656 679 656 679 0.94
Sequence Information
- Coding Sequence
- atgaataaaagtgaACCTATGTGCCGAATTTGTCTGTTTGAAGACAAAACCGGCTCCCGTTCACGGTTTGTCAGTATATTTAAACAGAATGAACAATTTAGCCAATTGAATTCCGAGTTTACAACCATTGAAGCCTTATTCGATATTTGCGGAATAAAGGTATTATTTGAAGACGTATATCCAAAAGTACTATGCGCCGCGTGCCATTTCAAGCTGGTTAAGGCATATAACCTTCGTAAGCAAGCGCAGCGCTCCCAACAAACGCTGACCAATATGCTGAATGAACAGCACCAACAAGATGCAAAGTCTGCCATACCGCTTCAAGATAAGCTGGATATGGCATGGGCGCAACCGGAATCGGACGAATTTATCGAAGAGGACTTAAATACTGACGAGGAAGCGGGACTGAATTGGAAACCTGAGGTCTTCGACGGTCAAGTGGAAGGTTCGATTGATGGACAGATTCGTTGTTGCGGTTGCGATGCGACGTTCGATAGAAAGGCACAGTTGCGAAAACATTCTTTTGAAGAGCATCGGCAATTAAGGCCAGCGGTGGTGGAAGGAAGTGAATATCAATGTAACATCTGTTATGCTCATTTTACTAGTAAGGCCTTGGTGGTGGCTCATAAGACCGGTAAAAATAATGCTCGACCACCGAAGAAGTGTGCTTTCTGCAAAGCTCTTTTTCGCACCGTACCGGAATTGGATGATCACGTGAGGGACATTCATTCGGACAACATGTTCAAATGTTGCGGTTGTGACTTGAGCACAACCAGTCGACAGAGGCTTGAAAATCATTCGAATATGCACAAGGAAGCTGATAAGAGAAAATGGAACCGCAAGCGAGTGACATTAAATAAGTACCAATGTTTCATTTGTTACGATCGGTTTAAGAATTTCGAAACATACCGTGCTCATGAACTTCTACCCTATGGTATATCTCGGAAGCAGCAATTTGAAAAAGATTTGTCTGCCACATTATCCCTATGCTGTGGTTGTAAGAAAGTTTTTGAAACAATTGGCGAGCTTAAAATTCACCAGGAGCAGGTACATAAACCGGACGCCTTCGAAGACGAGACACTTCCGATTGAATGTTCCGGTTGTTTCAAACGCTACCAAACTTCGTTCAAGTTGAAAGAGCATCTTCGTGCGTCAAAAAGTAGTCACTCTTTTGAATGCAGTAAATGCGTATCGGCCAGGCGTACACTTGAAGAGTTGTTGGAACACATGAAAATACATAAAGGGCCAAGAGGTTTTAGGTGCTGTGGGTGCTTTGAAGAATTCGATTCTCAGGAAAAACTTAAGCAACATTCTGAGGAACATGCCCGAACACCCAAAGTATATGAAGATGAGACAGAAATCGAACGTCCTTTCAAATGCCACATTTGTCACAAGAAATACAAATGTAAAGTAGATATTCGTCACCATCAACAGAACGTGTACTACGATAAGGTACATGTCTGCGACATCTGCGGCAAAGGATTTAGACATCCGCAAACATTAACCGTACATATAGCATCACATAAAGACAAATCCGAGCATAAATGTCCTGAATGTGGAAAAAAGTACAAACATGAACTGCTCGTCCGCAGCTGTCTAAGGCGGCACAAAAATCCTCGTGAGTAtcgttgtaaaatttgtaaaggaACCTTCAAGGCCCGAGGCAACTTAACTTCGCACATGATTTCGCACTCCGATGAACGAAAGTACGAATGCTGCATTTGTAATTTTTCCTTCAAACGCCCCGGTCACCTCAAAGATCATATGCTGATGCATACGAGCGAGCAAAGATTTCCCTGCCGATTTTGCTCACTAGTTTTGCGCTCACAATCGGAGAGGAGCACTCACGAGATTCGACACAGCGGACAATATCCGTATCAGTGCGAAATATGTGGCAAACAGCACACAAGACGTATGTTATACATCCAGCACTACGAAACGCATAAGGAAGACTCGACCAAGGTGCATGCATGTCATATGTGTACTCAACGGTACAGTCAGGACCATTTTTTGGCCAATCATCTCAAGTACGTGCATCGCATCGAATCTGCTGACCGAAGCTGGGATGCTAAGTTTCAACGACTAAATCATCGAAAAAAATCCGTCCGAACGACTTCAACAGACGTTGACAATGCAGGGGATGAAGAAATGGTTGCTGTTGAAACTACCAACGATAGTATGGTTTTGGATGACAAATAA
- Protein Sequence
- MNKSEPMCRICLFEDKTGSRSRFVSIFKQNEQFSQLNSEFTTIEALFDICGIKVLFEDVYPKVLCAACHFKLVKAYNLRKQAQRSQQTLTNMLNEQHQQDAKSAIPLQDKLDMAWAQPESDEFIEEDLNTDEEAGLNWKPEVFDGQVEGSIDGQIRCCGCDATFDRKAQLRKHSFEEHRQLRPAVVEGSEYQCNICYAHFTSKALVVAHKTGKNNARPPKKCAFCKALFRTVPELDDHVRDIHSDNMFKCCGCDLSTTSRQRLENHSNMHKEADKRKWNRKRVTLNKYQCFICYDRFKNFETYRAHELLPYGISRKQQFEKDLSATLSLCCGCKKVFETIGELKIHQEQVHKPDAFEDETLPIECSGCFKRYQTSFKLKEHLRASKSSHSFECSKCVSARRTLEELLEHMKIHKGPRGFRCCGCFEEFDSQEKLKQHSEEHARTPKVYEDETEIERPFKCHICHKKYKCKVDIRHHQQNVYYDKVHVCDICGKGFRHPQTLTVHIASHKDKSEHKCPECGKKYKHELLVRSCLRRHKNPREYRCKICKGTFKARGNLTSHMISHSDERKYECCICNFSFKRPGHLKDHMLMHTSEQRFPCRFCSLVLRSQSERSTHEIRHSGQYPYQCEICGKQHTRRMLYIQHYETHKEDSTKVHACHMCTQRYSQDHFLANHLKYVHRIESADRSWDAKFQRLNHRKKSVRTTSTDVDNAGDEEMVAVETTNDSMVLDDK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01462535;
- 90% Identity
- iTF_01462535;
- 80% Identity
- -