Basic Information

Insect: Topomyia yanbarensis
Gene Symbol: L
Assembly: GCA_030247195.1
Location: CM058070.1:10321053-10337402[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 1.2 1.2e+02 5.4 5.7 1 23 3 25 3 25 0.98

2 16 6.5e-07 6.6e-05 25.1 3.1 1 23 31 53 31 53 0.99

3 16 3e-05 0.003 19.9 0.3 1 23 59 81 59 81 0.98

4 16 0.29 29 7.4 0.5 2 23 185 207 184 207 0.96

5 16 0.47 48 6.7 0.2 1 23 347 369 347 369 0.95

6 16 0.38 39 7.0 0.3 1 23 379 401 379 401 0.94

7 16 0.014 1.5 11.5 1.4 1 23 409 433 409 433 0.92

8 16 0.08 8.2 9.1 0.1 1 23 438 461 438 461 0.93

9 16 0.0022 0.22 14.0 3.6 1 23 468 491 468 491 0.98

10 16 0.0037 0.38 13.3 2.0 1 23 523 545 523 546 0.96

11 16 0.0039 0.4 13.3 0.4 2 23 786 808 785 808 0.96

12 16 0.0087 0.89 12.1 0.1 1 23 814 836 814 836 0.98

13 16 0.71 73 6.1 5.7 2 23 844 865 844 866 0.94

14 16 0.36 37 7.1 1.6 2 23 998 1019 997 1019 0.95

15 16 0.029 3 10.5 0.2 1 23 1029 1051 1029 1051 0.96

16 16 0.0027 0.28 13.7 1.6 1 23 1058 1080 1058 1080 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	1.2	1.2e+02	5.4	5.7	1	23	3	25	3	25	0.98
2	16	6.5e-07	6.6e-05	25.1	3.1	1	23	31	53	31	53	0.99
3	16	3e-05	0.003	19.9	0.3	1	23	59	81	59	81	0.98
4	16	0.29	29	7.4	0.5	2	23	185	207	184	207	0.96
5	16	0.47	48	6.7	0.2	1	23	347	369	347	369	0.95
6	16	0.38	39	7.0	0.3	1	23	379	401	379	401	0.94
7	16	0.014	1.5	11.5	1.4	1	23	409	433	409	433	0.92
8	16	0.08	8.2	9.1	0.1	1	23	438	461	438	461	0.93
9	16	0.0022	0.22	14.0	3.6	1	23	468	491	468	491	0.98
10	16	0.0037	0.38	13.3	2.0	1	23	523	545	523	546	0.96
11	16	0.0039	0.4	13.3	0.4	2	23	786	808	785	808	0.96
12	16	0.0087	0.89	12.1	0.1	1	23	814	836	814	836	0.98
13	16	0.71	73	6.1	5.7	2	23	844	865	844	866	0.94
14	16	0.36	37	7.1	1.6	2	23	998	1019	997	1019	0.95
15	16	0.029	3	10.5	0.2	1	23	1029	1051	1029	1051	0.96
16	16	0.0027	0.28	13.7	1.6	1	23	1058	1080	1058	1080	0.95

Sequence Information

Coding Sequence: ATGCCATTCAAGTGTGAATACTGCGCTCGTTTGTTCAAACACAAGAGGTCAAGAGATCGCCATACCAAACTGCATACGGGAGATCGGCGATACCGGTGTCCTCACTGCGAAGCGGCTTTTTCAAGAAGTGATCATCTGAAAATTCACATGAAAACCCACGACAACCAGaagccttttcagtgcactatcTGCAACCGTGGCTACAATACGGCGGCAGCACTAACGAGCCACATGCAGAACCACAAGAAGCAAATTGCTCTAACCGGTAGTCCCAACTTGACCTACAGTCCCCGTTCGACCAGTTCGCTTTCTAGCAACGCATCCAATCCCAAAAGAAAATTCTCCCCGTACGAGCAGAACCTGATGATGATTAACCGTTCCAAGCTGTTAAAATCCGGCGATCTCACCTGCATATATTGCACACGGACGGATTTCGCTAACGTCGAGCAACTGGGAGCTCACGTTCAAACAATGCACAGCAATTTGCTTCTCAACGAAAACAACTTCCATCGCCATGCTTCACCGGACTCGTTGGTTCCCTATCCACCCATTTCTTGCGAATTTTGCACCATGAAGTTCCCGACTGTTCCGATGATGTTTAACCATCTCAAAACTACGCATTTGGACAGAATCAACAGTCCAAACAGTTACCTGGAACAGTTCAATAAGAACCTGATGAGTACATATACTTCGTTCTACGGGGCTGCACTGTTCGAGGACAAACATGAAACCGAAGGACGTGGTCAGGTCAAGAGTGAACGCCCCACCAGTCGGAAAAGTGTTCGGGATGAAAATGGAAACGAGAAAAGTCCCACCGTCGTCGATTCCAAATCCATCAAGCTGGAGAAAAAAGATGAAAATGATAATTCCCAGGAAGCACAGGAACAACTGGCGCCCACGGATTTGAGTCAACCTCGCATAAAAAAGCTAAAGATGGAGCATGAGAACCACTCGACTTCTAGTCCGGATAGTAAAGACACGGAAAAGGACAGTTCACCAAACGGGTCGAGTTCGATACTACCGACCCCACCCGGGGCCTATCTTTGCAACCAATGCAACGCCGCCCTCCCGGATTTTGAATCATTCCGAAGTCATCTGAAGGCTCACCTCGAGCAAGGATCGACCGCATCATCGTTCGTGTGTCAACAGTGTGGTGCCACACTTGGTGACCACCAGGAGTACGAAAAACACGTAACCGGCCATTATCTGGTTACCGGTGCGGAGTATCAGTGCGAAGCAAGCTGCAGCAAAAAGTTTGCCAAAGCGGATGAACTGCACAAACATCTGTACGATTCGCATACACAGGTGCTGTATAAATGTGCCCTCTGTAGCGAAACATTCGACAGTAAGGTGACTATTCAGGTGCACTTTGCAGTGGCGCATTCTACCGAGGTCAAGCTGTACCGGTGTTCGGCGTGTACGGAGATGTTCCGTTCGGAGCGAGAGTTCAGGCACCACATCCGCACACGGCACATCACAACTGGAGCGGTACAGTGTGTCTTCTGTCGGGTTGTCTGCTCATCCGAGTTGGAAATGCAATTTCATCTAGCCGCGCACGCCAGAAAATTCAAATGTCCAGCATGCCCAGAATCCTTCCACGTGGAGTTCCTACTGGATCGCCATATGCAAACCCATCACAGTCAGAAAGAGATAACCAATGCAGCAGCTGCTGCTGCAACCATCTCCAACAGTACTGGTAGCGGCGGTAACGCCAACAACAGCAATAATCTCGAATACTTGCAACTGCATGGCCAAATGGCTGCAGCCGCCGCTGgatggcaaaatttgtatgcGGCTAACAAGTTCTACAATCCTCTTCATGTCGACACACTAAACTCGATGAAGCACCCTAACTTCCTGCACGGATTCTACGACAGCCTGAATAAGACCCAAGCTCAGCGCTATTTGGAACAGGCCAAAAAAGGATTCGTTAGTCCAAACAACGTGACCCAATCGAAGGCACTGCTAAATCTGTACAATCAACGAACGGCTGCCATGAATGGACTGTACTCTCCTGACCACATCGGTGCTGGAAGTGCCGGTGTTGGTAATCAGCAAGCTACCGGTGGTAACTGTCCATCCAATACACCCGTTTCCGCCAAACCCACACAAACTTTTTCTCCAACCACGTTGCTGCATCGCTATGGAATTAATCCTTCAGGTAACACGCCCAATTCGAACAGCTCAGCAGGGCAGCCGAACCCGCCGGACAAATCAACATCGGTTAGTGCCAAAAATGGCACAACAAACAATTATTACAGTTGCGGCATTTGCGAGAGAAACGATTTCGGCACGGAAAATGAAGTTCAAACTCATAGAAAAATCGTGCACAATTTGAAGACTGGAGTCAGCCTTCGGTGCGCCTATTGCAGTGGAGATTTCCGGTCAAGAAACGAACTGGAGAACCATATGAAGATTACTCACAACACCGGTGGCAAGCACAAGTGCTTGATATGCGACGAAATCTTCCCCTCTCCAGCGGTCCTCGCCGAGCACAAGCTAACCCACTGCAAGGTCGGAGCGTCGGGACGTTGTTCACACTGTCCTACCACTTTGCCCGATGCGCACAGCTTCAAAACCCATCTCACACAGCATCATCAGCAACAATCTGCGAGCTCCGCACCGAACTCCAGTTCGATTGCCAGCAGTGGTAGCGGTTCTGGTCCAGGTCAGGAGCAGGAACGCTTCCCAATCCAGTGTATCTGCTGCCGGCAAACGCTCAACTCGGAATTCGAAATAAGTTTGCACGCAAAATTCCACACAAAGTCcattgaaacaaatgaaaaaacgTGCGCCCTCTGCTTAGAACCTTTGGCCCACGGACAAGAGGCTAAAATCTGTGAAAGTTGTTTAAAACGTCACAATTTCCCTTCGAAACTGCTTTCTATCAACAACTTTATCAAATCATCAGCAGCATCCTCAGCTTCAGCTGTTCCACCTCAAGAAGAGACGAACCACCAACAACTGCAGCAATCCACCAAAACCACTACCCAGTGTAACCTCTGCAAGAAACATCTCGTTGATACTCAAAAACTACAGGAGCATCTAATCGATCATACCTTCGCCGGGTGCGAGGATCGTGGCTATATATGCTATCTCTGTTCCTCCGTGTTCACGTCGTCGATGGGACTGCAAGTGCACATCACCGAGCACGGATCACAGGCTAAGCCGTACGACTGTAACCACTGTGATGAAGCGTTCTTCTTCCGGGCAGAACTTGAACACCATCTTATCGACCACGAGCTGGGTAAAGTTCATCTAGTTCCTAGAACCGACAGTGATCCACCGCACGAAGCTTCACTGCACATCAAGTCGGAAAAAATAGAGCACAGCACGGGAAAAGATGAAGATCACAGCCAAGATAGACAGGAAGCTTTGAAAGGAGAGCTGAACGAGCCGAAAGCAGGCTCACCCAGTGTGGACAGTGTGAACAGTGGCAACGGAAGCAGCTACCCGGAGCAGGAAGATTGCGATGAAGATGATGATGAGTATATAGAGGTAGAGCACAACGTTGAGGAGAGCGGAAAGGAATCGGCCGTTTCCAGTCGGGATGGCATTGAACGACCCGGTAAATAA
Protein Sequence: MPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQIALTGSPNLTYSPRSTSSLSSNASNPKRKFSPYEQNLMMINRSKLLKSGDLTCIYCTRTDFANVEQLGAHVQTMHSNLLLNENNFHRHASPDSLVPYPPISCEFCTMKFPTVPMMFNHLKTTHLDRINSPNSYLEQFNKNLMSTYTSFYGAALFEDKHETEGRGQVKSERPTSRKSVRDENGNEKSPTVVDSKSIKLEKKDENDNSQEAQEQLAPTDLSQPRIKKLKMEHENHSTSSPDSKDTEKDSSPNGSSSILPTPPGAYLCNQCNAALPDFESFRSHLKAHLEQGSTASSFVCQQCGATLGDHQEYEKHVTGHYLVTGAEYQCEASCSKKFAKADELHKHLYDSHTQVLYKCALCSETFDSKVTIQVHFAVAHSTEVKLYRCSACTEMFRSEREFRHHIRTRHITTGAVQCVFCRVVCSSELEMQFHLAAHARKFKCPACPESFHVEFLLDRHMQTHHSQKEITNAAAAAATISNSTGSGGNANNSNNLEYLQLHGQMAAAAAGWQNLYAANKFYNPLHVDTLNSMKHPNFLHGFYDSLNKTQAQRYLEQAKKGFVSPNNVTQSKALLNLYNQRTAAMNGLYSPDHIGAGSAGVGNQQATGGNCPSNTPVSAKPTQTFSPTTLLHRYGINPSGNTPNSNSSAGQPNPPDKSTSVSAKNGTTNNYYSCGICERNDFGTENEVQTHRKIVHNLKTGVSLRCAYCSGDFRSRNELENHMKITHNTGGKHKCLICDEIFPSPAVLAEHKLTHCKVGASGRCSHCPTTLPDAHSFKTHLTQHHQQQSASSAPNSSSIASSGSGSGPGQEQERFPIQCICCRQTLNSEFEISLHAKFHTKSIETNEKTCALCLEPLAHGQEAKICESCLKRHNFPSKLLSINNFIKSSAASSASAVPPQEETNHQQLQQSTKTTTQCNLCKKHLVDTQKLQEHLIDHTFAGCEDRGYICYLCSSVFTSSMGLQVHITEHGSQAKPYDCNHCDEAFFFRAELEHHLIDHELGKVHLVPRTDSDPPHEASLHIKSEKIEHSTGKDEDHSQDRQEALKGELNEPKAGSPSVDSVNSGNGSSYPEQEDCDEDDDEYIEVEHNVEESGKESAVSSRDGIERPGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00949134;
90% Identity: -
80% Identity: -