Basic Information

Insect: Topomyia yanbarensis
Gene Symbol: -
Assembly: GCA_030247195.1
Location: CM058068.1:187797090-187799643[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.24 24 7.6 1.2 2 23 215 237 214 237 0.96

2 14 0.28 29 7.4 0.7 6 23 246 263 246 263 0.98

3 14 0.57 58 6.4 0.1 2 21 276 297 275 300 0.88

4 14 0.00036 0.037 16.5 1.0 1 23 307 329 307 329 0.95

5 14 0.0031 0.32 13.6 4.8 2 23 338 359 337 360 0.94

6 14 0.02 2.1 11.0 0.5 2 23 445 467 444 467 0.96

7 14 4.5e-05 0.0046 19.3 0.7 1 23 499 522 499 522 0.94

8 14 0.00015 0.015 17.7 0.9 1 23 530 552 530 552 0.98

9 14 3.8e-06 0.00039 22.7 0.3 1 23 560 583 560 583 0.97

10 14 8.9e-05 0.0091 18.4 0.4 2 23 590 611 589 611 0.96

11 14 1.5 1.5e+02 5.1 1.5 2 21 622 641 621 642 0.94

12 14 0.37 37 7.0 0.1 2 23 650 672 649 672 0.93

13 14 0.007 0.71 12.5 0.7 1 23 678 700 678 700 0.92

14 14 0.00027 0.027 16.9 2.5 1 23 706 729 706 729 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.24	24	7.6	1.2	2	23	215	237	214	237	0.96
2	14	0.28	29	7.4	0.7	6	23	246	263	246	263	0.98
3	14	0.57	58	6.4	0.1	2	21	276	297	275	300	0.88
4	14	0.00036	0.037	16.5	1.0	1	23	307	329	307	329	0.95
5	14	0.0031	0.32	13.6	4.8	2	23	338	359	337	360	0.94
6	14	0.02	2.1	11.0	0.5	2	23	445	467	444	467	0.96
7	14	4.5e-05	0.0046	19.3	0.7	1	23	499	522	499	522	0.94
8	14	0.00015	0.015	17.7	0.9	1	23	530	552	530	552	0.98
9	14	3.8e-06	0.00039	22.7	0.3	1	23	560	583	560	583	0.97
10	14	8.9e-05	0.0091	18.4	0.4	2	23	590	611	589	611	0.96
11	14	1.5	1.5e+02	5.1	1.5	2	21	622	641	621	642	0.94
12	14	0.37	37	7.0	0.1	2	23	650	672	649	672	0.93
13	14	0.007	0.71	12.5	0.7	1	23	678	700	678	700	0.92
14	14	0.00027	0.027	16.9	2.5	1	23	706	729	706	729	0.97

Sequence Information

Coding Sequence: ATGACCGATAATTTGCAGAACTGTTTAACCTGCCGCCGACAAACAGAAAATTTCCTTCAAATACTGGATGAATCAAATGTGGAAAATGTAGAGGCTATACTAACAAAGCATTTCTGGTTTAAGACGGCAGAATACGAACATAGGGTTctttgcatcagctgctgggaGAAGATTGATGAATTTCACAAGTTTTACTGTGAAGTTGAGGAACGTTGGTGCAGCAAATCTGACTTGTTGGAGTCTGTTGTAAAGACTGAGCAACTTTTCGACGAGAATGAAGCACAGAGTGAGCTGTTTACTTGCGAACTGATAAAGGTGGAAGAAGAGAACACAAAATTGAAATCTGTTATCGATGGTAGCGAATCAGAGGAAAACAATATTGATGGGAATGTTAcagatgacgatgatgatgatgattatcTGCCAATCGGTGAGGACGCTATCGATTCAGAGTTTAAACAGGAAGATGAATCGTCGGAGGTTTCCACCGAAGAATCGTCCATGCCAATTGGAAAACGACGAAATATTACTCGTATGATGTCAGCCAGCCTAAAGGAACCGGCCCAAAAGAAACGGCATGTTAAATCTCTAAAAAGCATGAACCTCAAGAGAAACGCTTTGATAGCGAAATACGTTCAGCTTGTTTGCGATTTGTGTGGACACAAGTCGGAAACTTTTTCACGTTTACTCTTGCACTATCGAAGAATACACGAAATTCAAGGATATGTAACCTGTTGCAATCGGGCCTTCCAGAAGAAGTCTGGATTGTTCGAGCACTTGAGCCGGCACGAATCTGGGGCAAGGGAACCATCGCCGCCACAGATCCGTTGCGAGCTATGTGACGCTTCGAAAACGTTCAAGGACGAAGAAGGGCTACAGCTGCACAATGTGATATATCACTCCAAACAGGAGAAAACCTTCCAATGTGACCAGTGTGATAAGGCTTTCAGCAGTGAGTGGCATCTTTCGGGGCACAAAAGTTGGCATCAGAATGTGGCTAGTTTGAATATTCATTGTGACAAGTGTAATAAGTAtttCAATTCGATTCGTACACTCAACACGCACATGCGGGCACACCACGCAAAAGTAACCACAGCTTTGACAACATCAGCCAATTTATCCAACACAGTCAGCGTCACAGCTGAATCAACTATTCCGGAACCAATTATAGCTTGTGAAGAGCAAGACTCTACAATGGAGTATGCCACGCTAAAGCCATCCAATGTGATACCTATAGCCGCGAGTGTAACTTCAGAACCCCCCAAGAAAGGGGGAAAATCCGCAGAAGAAGTTGCAAAGGAAGATGAGTTCATTCGCCGGTTCTGTACTCTTGTTTGCGACAAGTGTGACTTTGCAGGAAGAAACTACTACCAACTCGATAAACACTTTAGAACCGATCATAATATGCGCGGCTATGCGATTTGCTGTGGGCGTAAATTTTGTAAGAAACGACGACTGTATGAGCATTGCCAGCGACACATCAATCCGGACATGTTTCGTTGTGAGATATGCAATAAATCGTTTACCGAGAGTAAGGGTTTAGAAAAGCACAATAAATGGGTTCACACGCCTGACTCGGAAAAGCCATTCAAGTGTGAAATTTGTGATGCTGCATTCTATAAAGACTATCTACTGCGAAATCATATGAAGTATCACATATCGATGGagcagaaaattttcaaatgcaaGGAATGTGACAAGTCatttggTACAGCAGTCCTACTTCGTGCTCATCAGCAAAATATTCATGGCGCTGTGTCCAGCTGGGTCTGTGATATTTGCGCCAAGGGATTCGTACACAAATCACTGTTGGAGAGACACAGAATCTCCCATTCGCCGGAGGGTGCGGCTAGTTTGAAAATGCAGTGTGAAAATTGTAAAAAGTGGTTGAAAAATAGAGACACCTATCAAAATCATCGGAAACGTTGTCTCGCTGGTGGTCCCGTGACGTGCGACGTTTGCGGCAAGGAAGCAGTGAACGAACTGGCTCTGGCTAGTCATAAACGGTTCAATCACGAAGAGCGACCCGCATTCGCGTGCAGCTATTGTGGAAAGCAGTTCAAACGAATCCTACGGTTAAAGGAGCACGAGGCGAACCATCGGGGTGAGGTACTGTACTCGTGTCCGTACTGTCCCAGAACGTGTAATTCCAGTTCCAACATGTACACCCACAAGAAGGTGGCCCATCCGGAGCTGTGGGCGGCCAAAGTGGCCGAGCGATTCTACAAGAAGTAA
Protein Sequence: MTDNLQNCLTCRRQTENFLQILDESNVENVEAILTKHFWFKTAEYEHRVLCISCWEKIDEFHKFYCEVEERWCSKSDLLESVVKTEQLFDENEAQSELFTCELIKVEEENTKLKSVIDGSESEENNIDGNVTDDDDDDDYLPIGEDAIDSEFKQEDESSEVSTEESSMPIGKRRNITRMMSASLKEPAQKKRHVKSLKSMNLKRNALIAKYVQLVCDLCGHKSETFSRLLLHYRRIHEIQGYVTCCNRAFQKKSGLFEHLSRHESGAREPSPPQIRCELCDASKTFKDEEGLQLHNVIYHSKQEKTFQCDQCDKAFSSEWHLSGHKSWHQNVASLNIHCDKCNKYFNSIRTLNTHMRAHHAKVTTALTTSANLSNTVSVTAESTIPEPIIACEEQDSTMEYATLKPSNVIPIAASVTSEPPKKGGKSAEEVAKEDEFIRRFCTLVCDKCDFAGRNYYQLDKHFRTDHNMRGYAICCGRKFCKKRRLYEHCQRHINPDMFRCEICNKSFTESKGLEKHNKWVHTPDSEKPFKCEICDAAFYKDYLLRNHMKYHISMEQKIFKCKECDKSFGTAVLLRAHQQNIHGAVSSWVCDICAKGFVHKSLLERHRISHSPEGAASLKMQCENCKKWLKNRDTYQNHRKRCLAGGPVTCDVCGKEAVNELALASHKRFNHEERPAFACSYCGKQFKRILRLKEHEANHRGEVLYSCPYCPRTCNSSSNMYTHKKVAHPELWAAKVAERFYKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00949095; iTF_01462431;
90% Identity: iTF_01462431;
80% Identity: -