Tyan040202.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Topomyia yanbarensis
Gene Symbol
-
Assembly
GCA_030247195.1
Location
CM058069.1:430027790-430030729[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.0042 0.43 13.1 0.3 1 23 239 261 239 261 0.97
2 14 2.2e-06 0.00022 23.5 1.9 2 23 268 289 267 289 0.98
3 14 8.7 8.8e+02 2.7 3.8 2 12 294 304 293 318 0.73
4 14 0.0007 0.071 15.6 0.1 3 23 356 376 355 376 0.97
5 14 0.8 82 6.0 0.4 3 23 456 477 454 477 0.92
6 14 0.033 3.4 10.3 0.3 3 21 485 503 485 504 0.96
7 14 0.59 60 6.4 2.7 1 23 513 536 513 536 0.95
8 14 1.8e-05 0.0018 20.6 1.1 1 23 560 582 560 582 0.98
9 14 1.4e-06 0.00014 24.1 5.2 1 23 589 611 589 611 0.98
10 14 6.4e-07 6.5e-05 25.2 1.2 3 23 625 645 623 645 0.96
11 14 1.3e-05 0.0014 21.0 2.5 1 23 651 673 651 673 0.99
12 14 2.5e-06 0.00026 23.3 2.2 3 23 681 701 679 701 0.97
13 14 4.3e-07 4.4e-05 25.7 1.3 1 23 707 729 707 729 0.99
14 14 0.0011 0.11 15.0 0.1 1 23 735 759 735 759 0.93

Sequence Information

Coding Sequence
ATGGAAGCAATGGATATGAACATCGAATACGATCTGACCAAGATATGTCGCTCGTGTCGCAGGGATGATCAGCAGCTGCAGTCCATATTCCATTGCGTGGGAACCGGAGGCATAACGCTGCATGAAATGCTCACCAATTGTACCCAGATTCAGGTTCACTATAATGACGGAATGCCGCACAATTTGTGTTCCACCTGCGTCACCGACATCAATACGGCGTACAACTTTCGAAGGCGTTACGAGCAGAGCGATATGATGTTGAGAGAATACATCGCTCGTCGGAGGGTTGTAGCCGGTGACAGTACGGACGATGGATCCGGAGTGGTTAAAGTAGAAATTTTCGACATTAAACCTGAGATCACGTACATCGAGGCAGACCCGTTGATCGGAGAGAAGTGCTTTGTATCGTCACTGGCGAAAATAGGAGCGTCAACCAGTTTGATACCGAACGACGAAGAGCACATCGAAGAACTGATCGAGGAAATCAACGACGAAGATGATTACACGGAACCCGATGTTGTTCAGGCTGAAATTGTGGACAATAGtgaagatgatgatgatgacgatgagaTAGATGAGGTGGAGAGCGATGGTGGGGTGGTGGATTACGTCGAAGACAGTTTGGATGATCTGATCGAGGAACTGGATGAAGCGAAACCCAGGAGGCAGGTTCACCACAAAAATAAAGGTTATTCGAAGATTAAAGGAGGACGGTTCATATGCGATGTATGCGAAAGAATTTTCATGGATAAGCGTGGCATTACGAATCATATGAAACTGCACGAACCGAAAGATTTGAAGCAGTGTTCCATCTGTGATCGAGGATTTGCCACAAATTACCACCTGGCTCGACATATGAAGAGCCACGAGAACGATACACAGTGTGAATATTGCGAGAAGAAATTTTCCTTTATGGCTTACAGTGATTACAGCAGACATATGGCATTAATGCATCCAGGTAAAGATCTGGTTCCTCAGAGGAAAACCGAAAAGCCCGAGCGTGAGATGGCACTAACAACGTTAACGGCAGAAATGGTTGAAGATAAAGGCAAAATGGAAGCCATCTGCCGGATTTGTGACATTACTTTCGATCGAATAGCTGAACTAAGGAATCACCTGAAAATTCATGCGGATCCAAAATCATACGCCAGCGTGAATATTCAAACGAAACCTTATCTGTTTGAGGAAGGTTACGTTCTGGAAAACTATCTGGATTATCTGGTCCAACAGGTCTGCAAATGGGATGTGCTTCGGTTCTATCAGATTGTGCAACCAGATGGCGAAGAGCTAGAGTTGAGTGACTCCGATTCTGAACCAGGCGAGGATGCTACCCCGGTGGAAGGCATCGTGCGCAGAAATCACCTTTGTGCTCTTTGCAATCAGAACTTTCCCAGGATAAGTAGTATCATGGAACATGCGAGAGAGCAGCACCCGGTGGAGGAGTTACTCGGATGTCGACACTGTGCAAAAGGATTTCCAAACAGTGCTCTTCTAGTGCGTCATTTGAAACAGCAGTGTGAGAATCACCAGAAGAAATTCTTTTGCACTTTCTGCAACGAGAAATTCATGTGGCAAACAAGCTTGAACAAACACGCCCAACGGAAGCACAAGCCATCGAAACCTCTGTGGGAGAAGCCAGACGATTCGAATGACACAAACGAAGGTAAGGAAAAGCAATACGTCTGTCAGGTATGCAGTAAAGGCTTCCAGCGGCTGGAACATCTGGAGCGTCACATCAAGATCCACATTCCGTCGGAGAAGAAATTCGAATGTACTCAGTGCCATAAGAAGTTCAACCGGAAGGACAACCTCCGGTCGCACATGAAAATCCACAAGAAAGACCCGCAGTTGGATATCAAGCAGAACCATTTGTGCGTCTACTGTGGTCGAGGTTTCTCCAATTCGTCAAACTTGATTGTGCACATGAGGCGGCACACTGGCGAGCGACCGTACAAGTGTGACATTTGTGATAAGGGATTCCCGCGGTCATCTGATTTGCAGTGCCATCGTAGAACACACACCGGTGAGAAACCTTGTCTGTGCACCATCTGTGGCAAAGGTTTTTCCAGATCCAACAAACTCGTTCGACACATGCGAATTCATACTGGAGCCAGACCATACACCTGCACCTACTGCGACCGTGCTTTCACCCAGTCGAACGACCTAACGTTGCACATCCGCCGACACACCGGCGAAAAGCCGTACGTCTGCGGTGTGTGTAACGAGCGCTTCATCCAGGGCACCGCACTGAAAGCTCATCAACGGGTGACAGGCCACTTCGATGACGGCAGTAATCAACCGGAACGGTTCGCAAGTATCAGCGTAAACAACCCGAACCGGCTTGGAATTAACGGGCCGAAGGCAGTTCGCCAGGGATCTTCCTCCGGCATTTCTCCTGACGATTTACCGAAAGTGGTTAAACCCGTTAAATCGAGGAAAAAAGCAACTGCCGCCAACAGTCGATCGTCCAGATCCCAACCAGCGCCAGCTGTTGAACCATCACGAGTCGAGTCGACTTCGGTTCATCCGACATCTGCCACCAATTCAGCACCTACTTCACCCACAATTGTGGACCATAGTAGAACTAATCTACAAAATCTTACTGGCCCGCCACATAGTTACGGTGCTGTGCCGTACATTATGCAAAACTATGACCTCGCGTCAACGGGTCTATTCTCGCAGAACTTCAATCAGCAGTAG
Protein Sequence
MEAMDMNIEYDLTKICRSCRRDDQQLQSIFHCVGTGGITLHEMLTNCTQIQVHYNDGMPHNLCSTCVTDINTAYNFRRRYEQSDMMLREYIARRRVVAGDSTDDGSGVVKVEIFDIKPEITYIEADPLIGEKCFVSSLAKIGASTSLIPNDEEHIEELIEEINDEDDYTEPDVVQAEIVDNSEDDDDDDEIDEVESDGGVVDYVEDSLDDLIEELDEAKPRRQVHHKNKGYSKIKGGRFICDVCERIFMDKRGITNHMKLHEPKDLKQCSICDRGFATNYHLARHMKSHENDTQCEYCEKKFSFMAYSDYSRHMALMHPGKDLVPQRKTEKPEREMALTTLTAEMVEDKGKMEAICRICDITFDRIAELRNHLKIHADPKSYASVNIQTKPYLFEEGYVLENYLDYLVQQVCKWDVLRFYQIVQPDGEELELSDSDSEPGEDATPVEGIVRRNHLCALCNQNFPRISSIMEHAREQHPVEELLGCRHCAKGFPNSALLVRHLKQQCENHQKKFFCTFCNEKFMWQTSLNKHAQRKHKPSKPLWEKPDDSNDTNEGKEKQYVCQVCSKGFQRLEHLERHIKIHIPSEKKFECTQCHKKFNRKDNLRSHMKIHKKDPQLDIKQNHLCVYCGRGFSNSSNLIVHMRRHTGERPYKCDICDKGFPRSSDLQCHRRTHTGEKPCLCTICGKGFSRSNKLVRHMRIHTGARPYTCTYCDRAFTQSNDLTLHIRRHTGEKPYVCGVCNERFIQGTALKAHQRVTGHFDDGSNQPERFASISVNNPNRLGINGPKAVRQGSSSGISPDDLPKVVKPVKSRKKATAANSRSSRSQPAPAVEPSRVESTSVHPTSATNSAPTSPTIVDHSRTNLQNLTGPPHSYGAVPYIMQNYDLASTGLFSQNFNQQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00949031;
90% Identity
-
80% Identity
-