Basic Information

Insect: Topomyia yanbarensis
Gene Symbol: ZNF646
Assembly: GCA_030247195.1
Location: CM058070.1:60485686-60488679[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 0.42 42 6.9 0.1 1 23 23 49 23 49 0.89

2 22 0.00014 0.015 17.8 0.7 2 20 63 81 62 83 0.94

3 22 3.6e-07 3.7e-05 25.9 0.8 1 23 153 175 153 175 0.99

4 22 0.51 52 6.6 0.1 3 23 309 330 307 330 0.91

5 22 2.2e-05 0.0022 20.4 1.5 1 23 337 360 337 360 0.98

6 22 1.7e-05 0.0017 20.7 0.6 1 23 365 387 365 387 0.97

7 22 0.0043 0.44 13.1 1.2 1 23 392 415 392 415 0.97

8 22 0.0027 0.27 13.8 0.1 1 23 422 444 422 444 0.97

9 22 1e-05 0.001 21.4 2.2 2 23 451 472 450 472 0.97

10 22 0.0011 0.11 15.0 0.3 1 23 481 505 481 505 0.96

11 22 0.0014 0.14 14.6 2.4 3 23 510 531 508 531 0.93

12 22 0.22 22 7.7 2.8 2 23 541 563 540 563 0.91

13 22 0.00055 0.055 15.9 0.1 2 23 570 591 569 591 0.96

14 22 0.00078 0.08 15.4 0.3 1 23 597 620 597 620 0.96

15 22 0.05 5.1 9.8 0.6 1 23 626 648 626 648 0.96

16 22 0.00025 0.025 17.0 1.2 1 23 663 686 663 686 0.93

17 22 5.2e-05 0.0053 19.2 0.1 1 23 692 714 692 714 0.99

18 22 2.6e-05 0.0026 20.1 0.2 2 23 721 742 720 742 0.96

19 22 5.8e-05 0.0059 19.0 1.8 2 23 750 771 749 771 0.97

20 22 0.00073 0.074 15.5 0.4 2 23 805 826 805 826 0.98

21 22 0.073 7.4 9.2 3.0 1 23 832 854 832 854 0.98

22 22 0.67 68 6.2 0.6 2 23 860 882 859 882 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	0.42	42	6.9	0.1	1	23	23	49	23	49	0.89
2	22	0.00014	0.015	17.8	0.7	2	20	63	81	62	83	0.94
3	22	3.6e-07	3.7e-05	25.9	0.8	1	23	153	175	153	175	0.99
4	22	0.51	52	6.6	0.1	3	23	309	330	307	330	0.91
5	22	2.2e-05	0.0022	20.4	1.5	1	23	337	360	337	360	0.98
6	22	1.7e-05	0.0017	20.7	0.6	1	23	365	387	365	387	0.97
7	22	0.0043	0.44	13.1	1.2	1	23	392	415	392	415	0.97
8	22	0.0027	0.27	13.8	0.1	1	23	422	444	422	444	0.97
9	22	1e-05	0.001	21.4	2.2	2	23	451	472	450	472	0.97
10	22	0.0011	0.11	15.0	0.3	1	23	481	505	481	505	0.96
11	22	0.0014	0.14	14.6	2.4	3	23	510	531	508	531	0.93
12	22	0.22	22	7.7	2.8	2	23	541	563	540	563	0.91
13	22	0.00055	0.055	15.9	0.1	2	23	570	591	569	591	0.96
14	22	0.00078	0.08	15.4	0.3	1	23	597	620	597	620	0.96
15	22	0.05	5.1	9.8	0.6	1	23	626	648	626	648	0.96
16	22	0.00025	0.025	17.0	1.2	1	23	663	686	663	686	0.93
17	22	5.2e-05	0.0053	19.2	0.1	1	23	692	714	692	714	0.99
18	22	2.6e-05	0.0026	20.1	0.2	2	23	721	742	720	742	0.96
19	22	5.8e-05	0.0059	19.0	1.8	2	23	750	771	749	771	0.97
20	22	0.00073	0.074	15.5	0.4	2	23	805	826	805	826	0.98
21	22	0.073	7.4	9.2	3.0	1	23	832	854	832	854	0.98
22	22	0.67	68	6.2	0.6	2	23	860	882	859	882	0.91

Sequence Information

Coding Sequence: ATGTTGCCAGTCCACGGTTTGCAGTCCATGTTCGAAACGATCGACTATCTGATCGTCCACGATGGTTACCAGTGTGCGGCCTGCCCGCAGGAGAAGCGCCGAAGCTTCCCCGATATGCCCGAACTCCGGCGGCACATGGTGAAACACGTCAACGGTGGTCGTACGTCGGGACGGCACTCGGAAATACGATGCAACCATTGCAATCAAACGTTCGACCGAGTGGATAACCTCCGGAAGCATCTGCTGGAGGCACTGAACAAAGAGTACGGTCGGGTAATCGACAGTGATGATATGGATGATGAAAAGCATTGTGTTAGCGATGCTCCAGTGAACTACATCATCAAGAATGGTTGTTTGACGTGTTCGGTGTGTGAAGCCGAATTCGGAGCACCCACCCGGTGGAACAAGGAGAAGTTTAAGATGCACGTCGGCAAGGAGCACTGGAAGACGCCGGCGTTCAGGTGTGACGATTGCGGAAAACGATTCAGCGAGGCTGGGAAGTTGGAGAAGCATATGAAGCGACACCTCGAACTGATGGATGTAGCGTGGATGGGTGCTGAACCATCTACGTCAAGCGgtgtcaaaataaaaaagagcTCAGATTCGGATTCCGATGATGCATTTTACGCGAAAGATCCTGTGGAATTGCAGCTAGATGAGATGCCATTACCTGAGGTTCACATCAAGGTCGAACCGGACGAAGAACAAAATCCGTTAGAGGAAGACAGGAGGGATGGTGAAGAGTCTTCCGTTTCAAATAGTTCCAGTGCATCTTCCGACTCGAGCGCGGGATCGGAATCTGACGTGCCGTATGTCGAAAAGACTAGAAAATACAAACCCAATCGAAAAGCCCGTAAATTGCGACACATTAAAGCTTCGTGTCGCGCGATTCCCGGTGCCAACGACGGTTCCATTATTCTAGCTTGCAATATATGTGACGAAGGATTTCTACTGCAAGATCTTCTCGATCGTCATATGGTTCAGAAACATGACGATCGCGATCGGCCGTACAGATGCTCGCACTGTGCGAAAACCTACATGACCAACGGGAACCTACAGGAGCACATACGAATGGTCCACGCGGGTGTCAAGTTCCCCTGCAAGGACTGTGGCATTAAACTGTCCACCAAGAGTTCCTGGAAGCGTCACATGAAGGGTCACACGGATGAAGGGTTCAGTTGCGCCATCTGCGCGGAAAAGTTTTCTTCTCATTCGGTGTTGGCCAAACACAAACGACGCGTTCACGAGAAGGCCGCCAACAATTTTATTTGCGTGGATTGCGGTAATACCTACGATACAAATGCTGCTCTGCGGGAACACCGTATTTCTCACACCGACGAACGGAGATGGGAGTGCAAGGTGTGtggtatgaaatttaaacgaaatCACAATTTGATAAACCACAGAAAGATTCATCTGGTTGATAAGCCAGTTGTCAAGTTCAAATGTCAGGAGGAAGATTGCAACCAAGAGTTTATAACGAAATCGGCTCTTGCTACCCACCGTTCCGCTCATGGAAGAGTGTGCTGCCGGTTGTGCTCTCGCACGTTCGAATCTCAAAGCGACCTGATGCAGCATCGCCGAGAGGATCACAAAATAACAGGAAAAGAAGCAGGTATCAGTTGTCGAACATGTCATAAACGCTGCGCTGATCACGATGCATTGCTAGCACATCGAGCCGAGGAACATCCGATGGAAGTTCCATTGGAGTGTGATATTTGCAAGGCTACATTTGCCTCGACGGTGGCACTACGAGCCCACCAGCGCGAACATCAGCGCGTTATCCTTTATAACTGTCCAAACTGTTCGGAAACGTACAACTCACAGCTGCTGCTGGAAACACACATGAAGGAAGTACACGCGGACTGTAAAAATCACGTGTGCTATATGTGCGGTAGTGGATACCCGACCCGGAAGCAGCTGGTTTCTCATCTGGGCAGGCATCGAAATCCTCAGAGGAAAACAAATTCCAACATGCCCGGTAACTACATGTGCGATATCTGCGGGAAGGAATTTAATTTCCGAATTACGCTGAAGAGGCATGTCTACAATTTCCATGATCACGACAGAAAGTTCCAGTGCGAGGTTTGCGAGAAAACGCTAGTGTCAGCGGAGGGATTGAAGTTGCATATGCGAAGCCACTCCGAGGATCAATTGGTGATGTGCGAACTTTGCGGAAAAGGTTTCTCCCAGCCGTACCGGCTGCGTGAGCATATGATTCGTCATTCCCGCGAAGCAAACGAACAACGATGCCATATCTGTAACCGCGCCTTCCGCGACCCAAATAAACTCGAGCTACACCTCAAATCCCACACCGGTGAGACGGAATTCTGCTGCATTCCATGTCAGCGTTATTTTGCTACCGATCGGCACTACCGGCTTCACGTGAAGCGTATGCACGAATCGGAAGCAACCTGTCCAATATGTGATAAGCTTTTTCCCACGGAGAAGAAAATGAAGAGCCACGTTCGGATTCACGAGAATCCGCACATGTTTGAATGTCCCACGTGCTTTGCCTGCATCAAGGAAAAGAAACAATTCGATCGTCATATGCGACTGCACACTGGCGTACGATTACCGTGCCAGTTTTGTCCGTTGACATTCTCGATGCCCAAGACGAGAAGAACACACGAGGCCCGGTTCCACAAGGATCAGCGGGGGACGATACTGGAGAAAGATGCTGACGGGGAGAAGGATAAGGAAAGTCCCAGCAAAAAATCAGTAGATGATACGGCTTTACTAGAGGTTCAGAGTGATTTCAGGGCTATACCCGTCAGAGAGGATGAGGTTAGCGTCGGGTAA
Protein Sequence: MLPVHGLQSMFETIDYLIVHDGYQCAACPQEKRRSFPDMPELRRHMVKHVNGGRTSGRHSEIRCNHCNQTFDRVDNLRKHLLEALNKEYGRVIDSDDMDDEKHCVSDAPVNYIIKNGCLTCSVCEAEFGAPTRWNKEKFKMHVGKEHWKTPAFRCDDCGKRFSEAGKLEKHMKRHLELMDVAWMGAEPSTSSGVKIKKSSDSDSDDAFYAKDPVELQLDEMPLPEVHIKVEPDEEQNPLEEDRRDGEESSVSNSSSASSDSSAGSESDVPYVEKTRKYKPNRKARKLRHIKASCRAIPGANDGSIILACNICDEGFLLQDLLDRHMVQKHDDRDRPYRCSHCAKTYMTNGNLQEHIRMVHAGVKFPCKDCGIKLSTKSSWKRHMKGHTDEGFSCAICAEKFSSHSVLAKHKRRVHEKAANNFICVDCGNTYDTNAALREHRISHTDERRWECKVCGMKFKRNHNLINHRKIHLVDKPVVKFKCQEEDCNQEFITKSALATHRSAHGRVCCRLCSRTFESQSDLMQHRREDHKITGKEAGISCRTCHKRCADHDALLAHRAEEHPMEVPLECDICKATFASTVALRAHQREHQRVILYNCPNCSETYNSQLLLETHMKEVHADCKNHVCYMCGSGYPTRKQLVSHLGRHRNPQRKTNSNMPGNYMCDICGKEFNFRITLKRHVYNFHDHDRKFQCEVCEKTLVSAEGLKLHMRSHSEDQLVMCELCGKGFSQPYRLREHMIRHSREANEQRCHICNRAFRDPNKLELHLKSHTGETEFCCIPCQRYFATDRHYRLHVKRMHESEATCPICDKLFPTEKKMKSHVRIHENPHMFECPTCFACIKEKKQFDRHMRLHTGVRLPCQFCPLTFSMPKTRRTHEARFHKDQRGTILEKDADGEKDKESPSKKSVDDTALLEVQSDFRAIPVREDEVSVG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00948997;
90% Identity: -
80% Identity: -