Basic Information

Insect: Topomyia yanbarensis
Gene Symbol: ZBTB46_1
Assembly: GCA_030247195.1
Location: CM058070.1:10044537-10046033[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.12 12 8.6 0.1 3 23 11 30 9 30 0.95

2 17 2.6e-08 2.6e-06 29.5 0.9 1 23 36 58 36 58 0.99

3 17 0.00046 0.047 16.2 0.1 1 23 64 86 64 86 0.93

4 17 0.00093 0.094 15.2 5.2 1 23 92 115 92 115 0.96

5 17 3.1e-06 0.00031 23.0 1.6 1 23 121 143 121 143 0.98

6 17 0.00087 0.088 15.3 3.2 1 23 149 171 149 171 0.98

7 17 0.00015 0.015 17.7 3.2 1 23 177 199 177 199 0.96

8 17 0.0031 0.31 13.6 1.4 1 23 205 227 205 227 0.97

9 17 0.0014 0.14 14.7 0.8 1 23 233 255 233 255 0.97

10 17 2.2e-07 2.3e-05 26.6 1.0 1 23 261 283 261 283 0.98

11 17 0.00022 0.023 17.2 5.6 1 20 289 308 289 311 0.95

12 17 6e-07 6.1e-05 25.2 0.9 1 23 317 339 317 339 0.99

13 17 0.00011 0.011 18.1 2.4 1 23 345 367 345 367 0.97

14 17 6.5e-05 0.0066 18.8 4.7 1 23 372 394 372 394 0.98

15 17 4.3e-06 0.00044 22.6 0.4 1 23 400 422 400 422 0.98

16 17 1.2e-07 1.2e-05 27.4 1.1 1 23 430 452 430 452 0.98

17 17 0.00015 0.015 17.7 3.0 1 23 458 480 458 480 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.12	12	8.6	0.1	3	23	11	30	9	30	0.95
2	17	2.6e-08	2.6e-06	29.5	0.9	1	23	36	58	36	58	0.99
3	17	0.00046	0.047	16.2	0.1	1	23	64	86	64	86	0.93
4	17	0.00093	0.094	15.2	5.2	1	23	92	115	92	115	0.96
5	17	3.1e-06	0.00031	23.0	1.6	1	23	121	143	121	143	0.98
6	17	0.00087	0.088	15.3	3.2	1	23	149	171	149	171	0.98
7	17	0.00015	0.015	17.7	3.2	1	23	177	199	177	199	0.96
8	17	0.0031	0.31	13.6	1.4	1	23	205	227	205	227	0.97
9	17	0.0014	0.14	14.7	0.8	1	23	233	255	233	255	0.97
10	17	2.2e-07	2.3e-05	26.6	1.0	1	23	261	283	261	283	0.98
11	17	0.00022	0.023	17.2	5.6	1	20	289	308	289	311	0.95
12	17	6e-07	6.1e-05	25.2	0.9	1	23	317	339	317	339	0.99
13	17	0.00011	0.011	18.1	2.4	1	23	345	367	345	367	0.97
14	17	6.5e-05	0.0066	18.8	4.7	1	23	372	394	372	394	0.98
15	17	4.3e-06	0.00044	22.6	0.4	1	23	400	422	400	422	0.98
16	17	1.2e-07	1.2e-05	27.4	1.1	1	23	430	452	430	452	0.98
17	17	0.00015	0.015	17.7	3.0	1	23	458	480	458	480	0.97

Sequence Information

Coding Sequence: ATGTCTTCGAAGCAGCAGAAGCGAACAGACTGTGAggtatgtggccaaaaagtccTTCGGGCGCTGCTGAAGCGACACATGGCCAGCCACACAGGCGAGCGGCCATACAAATGTGAAATATGTGGCAAAGTATTTATCCAAAAGAGAGACCTGCAGCGTCACACGATGACTCACACTGGTGAGCGGCCATACAAATGTGGGATATGTGACAAAATATTCGCCCAGCCCGATTACTTAACTTTTCATGAACTTATTCACAGTGGTGATCGTCCGCATAAATGTGAAATGTGTGGCAAACAATTTACGCTGAAGCATCGCCTGCAGCGACACGTTTCTATGACCCATACTGCCGAGCGACTGTACAAATGTAAGATATGTGACAAAGCATATAAACAGCAGTATGATCTGAACTTGCACAAACTCAGTCACAGTAATGAACGACAGCATAAGTGCGAAGTATGCGATAAAGAATACCTCCACAAAAAGTCCCTGCAATGGCACATGGCAACCCACGTTGGCGAGCGTCCGCACAGGTGTGATGTTTGCGGCAAAGCATTTATCCATCAGCGTTACTTGACAATACATAAATTCATTCACAGTAGTGATTTGCCGCATACGTGTGAGGTGTGTGGCAAACAATACGCACTGAAGAATCGCCTGAAGCTACACATATCCAGCCACACTGGCGAGAAACCGCACAAATGTGAAATATGTGACAAAGTATTTCTTCGTCGGGATCGCCTAGTTGCGCACAAACTTGTGCACACTAGTAGGCTGCCGCATAAGTGCGAAGTGTGTGGCAAAGTATTCTTTCAGGAGGGTGACCTGCAGCGACACATGTTGACTCACACTAGCGAGCGGCCGTATAAATGTGAAATATGTGACAAGGCGTTTCATCATAACACTAACCTGCAGAAACACGTGTTATGTCACACTGGCAAGCGGCCATATAAATGTGAAACGTGTAGCAAAGTATTTGTTCAAAAGGCTGACCTGCAACGACACAGGATTACTCACACTAGTGAACGTCCGTTTAAATGTGGAACATGTGACAAAACATTTGCCCGGAAAAATTATTTACATTTACATGAACTTATTCATGGTGATCGTCCGCATAAATGTGAAGTGTGCGGCAAACAATTCACACTGAAGCATCGCCTTCAGCGGCACATTGAAACCCACACTAGTGAGCGCCCGTACAAATGTGATGTATGTGGCAAAGCATATAAACAGCAGTCTGTTTTGAACTCGCACAGACTCATTCATAGTAATAAAGACGAGTATCCGTACAAATGTGACATATGTGGCAAAGCATTCAACCACCGGAGTAGCTTAAAGTTGCACATACTCATTCACAATGGTGAACGTTCGCATAAGTGCGATATGTGTGGCAAAACATTTTTACGCAAACAGACCCTTCAGCGGCACGTTGTAACTCACACTGGCAAGCGTACACTAAAAGATACAACAAGTGCAAGTGTGATACTATGTGGATGA
Protein Sequence: MSSKQQKRTDCEVCGQKVLRALLKRHMASHTGERPYKCEICGKVFIQKRDLQRHTMTHTGERPYKCGICDKIFAQPDYLTFHELIHSGDRPHKCEMCGKQFTLKHRLQRHVSMTHTAERLYKCKICDKAYKQQYDLNLHKLSHSNERQHKCEVCDKEYLHKKSLQWHMATHVGERPHRCDVCGKAFIHQRYLTIHKFIHSSDLPHTCEVCGKQYALKNRLKLHISSHTGEKPHKCEICDKVFLRRDRLVAHKLVHTSRLPHKCEVCGKVFFQEGDLQRHMLTHTSERPYKCEICDKAFHHNTNLQKHVLCHTGKRPYKCETCSKVFVQKADLQRHRITHTSERPFKCGTCDKTFARKNYLHLHELIHGDRPHKCEVCGKQFTLKHRLQRHIETHTSERPYKCDVCGKAYKQQSVLNSHRLIHSNKDEYPYKCDICGKAFNHRSSLKLHILIHNGERSHKCDMCGKTFLRKQTLQRHVVTHTGKRTLKDTTSASVILCG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -